Four new colchicinoids, gloriosamines A-D, from Gloriosa rothschildiana

Tetrahedron Letters

Volumn 49, Issue 2, 2008, Pages 257-260

  Kitajima, Mariko ^a   Tanaka, Akiko ^a   Kogure, Noriyuki ^a   Takayama, Hiromitsu ^a  

^a CHIBA UNIVERSITY   (Japan)

Author keywords

Alkaloid; Chemical conversion; Colchicine; Gloriosa; Structure elucidation

Indexed keywords

COLCHICINE DERIVATIVE; COLCHICINOID; GLORIOSAMINE A; GLORIOSAMINE B; GLORIOSAMINE C; GLORIOSAMINE D; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG ACTIVITY; DRUG ISOLATION; DRUG STRUCTURE; DRUG SYNTHESIS; GLORIOSA ROTHSCHILDIANA; HUMAN; HUMAN CELL; IC 50; NONHUMAN; PLANT; PROTON NUCLEAR MAGNETIC RESONANCE;

GLORIOSA; GLORIOSA ROTHSCHILDIANA;

EID: 36849066221     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2007.11.061     Document Type: Article

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5. 7 414.1553). CD (c 0.45 mmol/L, MeOH, 25 °C) Δε (λ nm): 0 (396), -7.0 (346), -3.5 (294), -6.8 (262), 0 (251), +11.7 (237), +1.5 (216).
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13. 7 414.1553). CD (c 0.23 mmol/L, MeOH, 25 °C) Δε (λ nm): 0 (381), -5.3 (346), -1.2 (285), -3.9 (264), 0 (251), +6.6 (239), 0 (226), -4.5 (217), 0 (210).
14. 8 430.1502). CD (c 0.17 mmol/L, MeOH, 22 °C) Δε (λ nm): 0 (393), -3.2 (347), -2.1 (316), -4.0 (291), 0 (252), +4.5 (232), 0 (219), -0.4 (215), 0 (212).
15. 8 432.1658). CD (c 0.24 mmol/L, MeOH, 25 °C) Δε (λ nm): 0 (396), -7.7 (353), -4.2 (318), -8.7 (289), -6.0 (262), 0 (247), +12.2 (234), 0 (225), -6.3 (217), 0 (208).
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