Syntheses and biological evaluation of ring-C modified colchicine analogs

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 12, 2010, Pages 3831-3833

  Yang, Baiyuan ^a   Zhu, Zhiqing C ^a   Goodson, Holly V ^a   Miller, Marvin J ^a  

^a UNIVERSITY OF NOTRE DAME   (United States)

Author keywords

2 Nitrosopyridine; Colchicine; Cytotoxicity; Microtubule; Nitroso Diels Alder

Indexed keywords

COLCHICINE; COLCHICINE DERIVATIVE; ISOCOLCHICINE; TUBULIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; BREAST CANCER; CANCER CELL CULTURE; CELL STRAIN MCF 7; CHEMICAL MODIFICATION; CONTROLLED STUDY; DIELS ALDER REACTION; DRUG CYTOTOXICITY; DRUG PROTEIN BINDING; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MICROTUBULE ASSEMBLY; PROSTATE CANCER; STEREOCHEMISTRY;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; COLCHICINE; CYTOTOXINS; HUMANS; PRODRUGS; STRUCTURE-ACTIVITY RELATIONSHIP; TUBULIN;

ALNUS;

EID: 77954212976     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.03.056     Document Type: Article

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