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Volumn 107, Issue 4, 2012, Pages 735-747

Peroxisome deficient aP2-Pex5 knockout mice display impaired white adipocyte and muscle function concomitant with reduced adrenergic tone

Author keywords

Adipose tissue; Adrenergic signaling; Insulin resistance; Peroxisomes; Shivering thermogenesis

Indexed keywords

ADRENALIN; CARNITINE PALMITOYLTRANSFERASE I; CATECHOLAMINE; CD36 ANTIGEN; DOPAMINE BETA MONOOXYGENASE; GLUCOSE TRANSPORTER 4; GLYCOGEN PHOSPHORYLASE; ISOPRENALINE; LEPTIN; MESSENGER RNA; NORADRENALIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHENYLETHANOLAMINE N METHYLTRANSFERASE; PROTEIN KINASE B; TYROSINE 3 MONOOXYGENASE;

EID: 84869878404     PISSN: 10967192     EISSN: 10967206     Source Type: Journal    
DOI: 10.1016/j.ymgme.2012.10.015     Document Type: Article
Times cited : (19)

References (66)
  • 1
    • 77956867734 scopus 로고    scopus 로고
    • Biochemistry and genetics of inherited disorders of peroxisomal fatty acid metabolism
    • Van Veldhoven P.P. Biochemistry and genetics of inherited disorders of peroxisomal fatty acid metabolism. J. Lipid Res. 2010, 51:2863-2895.
    • (2010) J. Lipid Res. , vol.51 , pp. 2863-2895
    • Van Veldhoven, P.P.1
  • 2
    • 33746366462 scopus 로고    scopus 로고
    • Biochemistry of mammalian peroxisomes revisited
    • Wanders R.J.A., Waterham H.R. Biochemistry of mammalian peroxisomes revisited. Annu. Rev. Biochem. 2006, 75:295-332.
    • (2006) Annu. Rev. Biochem. , vol.75 , pp. 295-332
    • Wanders, R.J.A.1    Waterham, H.R.2
  • 4
    • 33845304296 scopus 로고    scopus 로고
    • Peroxisomal disorders: the single peroxisomal enzyme deficiencies
    • Wanders R.J., Waterham H.R. Peroxisomal disorders: the single peroxisomal enzyme deficiencies. Biochim. Biophys. Acta 2006, 1763:1707-1720.
    • (2006) Biochim. Biophys. Acta , vol.1763 , pp. 1707-1720
    • Wanders, R.J.1    Waterham, H.R.2
  • 5
    • 19444371845 scopus 로고    scopus 로고
    • Peroxisome biogenesis disorders: the role of peroxisomes and metabolic dysfunction in developing brain
    • Faust P.L., Banka D., Siriratsivawong R., Ng V.G., Wikander T.M. Peroxisome biogenesis disorders: the role of peroxisomes and metabolic dysfunction in developing brain. J. Inherit. Metab. Dis. 2005, 28:369-383.
    • (2005) J. Inherit. Metab. Dis. , vol.28 , pp. 369-383
    • Faust, P.L.1    Banka, D.2    Siriratsivawong, R.3    Ng, V.G.4    Wikander, T.M.5
  • 6
    • 33845462129 scopus 로고    scopus 로고
    • Generalised and conditional inactivation of Pex genes in mice
    • Baes M., Van Veldhoven P.P. Generalised and conditional inactivation of Pex genes in mice. Biochim. Biophys. Acta 2006, 1763:1785-1793.
    • (2006) Biochim. Biophys. Acta , vol.1763 , pp. 1785-1793
    • Baes, M.1    Van Veldhoven, P.P.2
  • 7
    • 68949151976 scopus 로고    scopus 로고
    • Peroxisomes, myelination, and axonal integrity in the CNS
    • Baes M., Aubourg P. Peroxisomes, myelination, and axonal integrity in the CNS. Neuroscientist 2009, 15:367-379.
    • (2009) Neuroscientist , vol.15 , pp. 367-379
    • Baes, M.1    Aubourg, P.2
  • 8
    • 84864046565 scopus 로고    scopus 로고
    • Mouse models for peroxisome biogenesis defects and beta-oxidation enzyme deficiencies
    • Baes M., Van Veldhoven P.P. Mouse models for peroxisome biogenesis defects and beta-oxidation enzyme deficiencies. Biochim. Biophys. Acta 2012, 1822:1489-1500.
    • (2012) Biochim. Biophys. Acta , vol.1822 , pp. 1489-1500
    • Baes, M.1    Van Veldhoven, P.P.2
  • 9
    • 33645877112 scopus 로고    scopus 로고
    • Peroxisomal multifunctional protein 2 is essential for lipid homeostasis in Sertoli cells and for male fertility in mice
    • Huyghe S., Schmalbruch H., De Gendt K., Verhoeven G., Guillou F., Van Veldhoven P.P., Baes M. Peroxisomal multifunctional protein 2 is essential for lipid homeostasis in Sertoli cells and for male fertility in mice. Endocrinology 2006, 147:2228-2236.
    • (2006) Endocrinology , vol.147 , pp. 2228-2236
    • Huyghe, S.1    Schmalbruch, H.2    De Gendt, K.3    Verhoeven, G.4    Guillou, F.5    Van Veldhoven, P.P.6    Baes, M.7
  • 11
    • 2142652105 scopus 로고    scopus 로고
    • Sequential ordered fatty acid α-oxidation and delta 9 desaturation are major determinants of lipid storage and utilization in differentiating adipocytes
    • Su X., Han X., Yang J., Mancuso D.J., Chen J., Bickel P.E., Gross R.W. Sequential ordered fatty acid α-oxidation and delta 9 desaturation are major determinants of lipid storage and utilization in differentiating adipocytes. Biochemistry 2004, 43:5033-5044.
    • (2004) Biochemistry , vol.43 , pp. 5033-5044
    • Su, X.1    Han, X.2    Yang, J.3    Mancuso, D.J.4    Chen, J.5    Bickel, P.E.6    Gross, R.W.7
  • 13
    • 33748657539 scopus 로고    scopus 로고
    • Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs
    • Hunt M.C., Rautanen A., Westin M.A.K., Svensson L.T., Alexson S.E.H. Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs. FASEB J. 2006, 20:1855-1864.
    • (2006) FASEB J. , vol.20 , pp. 1855-1864
    • Hunt, M.C.1    Rautanen, A.2    Westin, M.A.K.3    Svensson, L.T.4    Alexson, S.E.H.5
  • 14
    • 34848817129 scopus 로고    scopus 로고
    • Peroxisomes contain a specific phytanoyl-CoA/pristanoyl-CoA thioesterase acting as a novel auxiliary enzyme in alpha-and beta-oxidation of methyl-branched fatty acids in mouse
    • Westin M.A.K., Hunt M.C., Alexson S.E.H. Peroxisomes contain a specific phytanoyl-CoA/pristanoyl-CoA thioesterase acting as a novel auxiliary enzyme in alpha-and beta-oxidation of methyl-branched fatty acids in mouse. JBC 2007, 282:26707-26716.
    • (2007) JBC , vol.282 , pp. 26707-26716
    • Westin, M.A.K.1    Hunt, M.C.2    Alexson, S.E.H.3
  • 15
    • 73149109060 scopus 로고    scopus 로고
    • ABCD2 is abundant in adipose tissue and opposes the accumulation of dietary erucic acid (C22:1) in fat
    • Liu J., Sabeva N.S., Bhatnagar S., Li X., Pujol A., Graf G.A. ABCD2 is abundant in adipose tissue and opposes the accumulation of dietary erucic acid (C22:1) in fat. J. Lipid Res. 2010, 51:162-168.
    • (2010) J. Lipid Res. , vol.51 , pp. 162-168
    • Liu, J.1    Sabeva, N.S.2    Bhatnagar, S.3    Li, X.4    Pujol, A.5    Graf, G.A.6
  • 16
    • 0034737640 scopus 로고    scopus 로고
    • Induction of the peroxisomal glycerolipid-synthesizing enzymes during differentiation of 3T3-L1 adipocytes. Role in triacylglycerol synthesis
    • Hajra A.K., Larkins L.K., Das A.K., Hemati N., Erickson R.L., MacDougald O.A. Induction of the peroxisomal glycerolipid-synthesizing enzymes during differentiation of 3T3-L1 adipocytes. Role in triacylglycerol synthesis. J. Biol. Chem. 2000, 275:9441-9446.
    • (2000) J. Biol. Chem. , vol.275 , pp. 9441-9446
    • Hajra, A.K.1    Larkins, L.K.2    Das, A.K.3    Hemati, N.4    Erickson, R.L.5    MacDougald, O.A.6
  • 19
    • 0015151575 scopus 로고
    • Observations on peroxisomes in brown adipose tissue of the rat
    • Ahlabo I., Barnard T. Observations on peroxisomes in brown adipose tissue of the rat. J. Histochem. Cytochem. 1971, 19:670-675.
    • (1971) J. Histochem. Cytochem. , vol.19 , pp. 670-675
    • Ahlabo, I.1    Barnard, T.2
  • 20
    • 0017369252 scopus 로고
    • Enzymic and morphological studies on catalase positive particles from brown fat of cold adapted rats
    • Pavelka M., Goldenberg H., Huttinger M., Kramar R. Enzymic and morphological studies on catalase positive particles from brown fat of cold adapted rats. Histochemistry 1976, 50:47-55.
    • (1976) Histochemistry , vol.50 , pp. 47-55
    • Pavelka, M.1    Goldenberg, H.2    Huttinger, M.3    Kramar, R.4
  • 21
    • 0018249838 scopus 로고
    • Beta-oxidation in peroxisomes of brown adipose tissue
    • Kramar R., Huttinger M., Gmeiner B., Goldenberg H. Beta-oxidation in peroxisomes of brown adipose tissue. BBA 1978, 531:353-356.
    • (1978) BBA , vol.531 , pp. 353-356
    • Kramar, R.1    Huttinger, M.2    Gmeiner, B.3    Goldenberg, H.4
  • 22
    • 78650575544 scopus 로고    scopus 로고
    • Transcriptional coactivator PGC-1alpha promotes peroxisomal remodeling and biogenesis
    • Bagattin A., Hugendubler L., Mueller E. Transcriptional coactivator PGC-1alpha promotes peroxisomal remodeling and biogenesis. Proc. Natl. Acad. Sci. U. S. A. 2010, 107:20376-20381.
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 20376-20381
    • Bagattin, A.1    Hugendubler, L.2    Mueller, E.3
  • 23
    • 69249219335 scopus 로고    scopus 로고
    • Peroxisome matrix and membrane protein biogenesis
    • Ma C., Subramani S. Peroxisome matrix and membrane protein biogenesis. IUBMB Life 2009, 61:713-722.
    • (2009) IUBMB Life , vol.61 , pp. 713-722
    • Ma, C.1    Subramani, S.2
  • 24
    • 76749118930 scopus 로고    scopus 로고
    • Ectopic recombination in the central and peripheral nervous system by aP2/FABP4-Cre mice: implications for metabolism research
    • Martens K., Bottelbergs A., Baes M. Ectopic recombination in the central and peripheral nervous system by aP2/FABP4-Cre mice: implications for metabolism research. FEBS Lett. 2010, 584:1054-1058.
    • (2010) FEBS Lett. , vol.584 , pp. 1054-1058
    • Martens, K.1    Bottelbergs, A.2    Baes, M.3
  • 25
    • 33748747113 scopus 로고    scopus 로고
    • Selective expression of an aP2/Fatty acid binding protein 4-Cre transgene in non-adipogenic tissues during embryonic development
    • Urs S., Harrington A., Liaw L., Small D. Selective expression of an aP2/Fatty acid binding protein 4-Cre transgene in non-adipogenic tissues during embryonic development. Transgenic Res. 2006, 15:647-653.
    • (2006) Transgenic Res. , vol.15 , pp. 647-653
    • Urs, S.1    Harrington, A.2    Liaw, L.3    Small, D.4
  • 26
    • 38749106909 scopus 로고    scopus 로고
    • d.Van aP2-Cre-mediated expression activation of an oncogenic PLAG1 transgene results in cavernous angiomatosis in mice
    • (V)
    • Van D.F., Scroyen I., Declercq J., Sciot R., Kahn B., Lijnen R., d.Van aP2-Cre-mediated expression activation of an oncogenic PLAG1 transgene results in cavernous angiomatosis in mice. Int. J. Oncol. 2008, 32:33-40. (V).
    • (2008) Int. J. Oncol. , vol.32 , pp. 33-40
    • Van, D.F.1    Scroyen, I.2    Declercq, J.3    Sciot, R.4    Kahn, B.5    Lijnen, R.6
  • 28
  • 29
    • 0036198394 scopus 로고    scopus 로고
    • Generation of Pex5-IoxP mice allowing the conditional elimination of peroxisomes
    • Baes M., Dewerchin M., Janssen A., Collen D., Carmeliet P. Generation of Pex5-IoxP mice allowing the conditional elimination of peroxisomes. Genesis 2002, 32:177-178.
    • (2002) Genesis , vol.32 , pp. 177-178
    • Baes, M.1    Dewerchin, M.2    Janssen, A.3    Collen, D.4    Carmeliet, P.5
  • 32
    • 0037090881 scopus 로고    scopus 로고
    • Efficient recombination in diverse tissues by a tamoxifen-iniducible form of Cre: a tool for temporally regulated Cre activation/inactivation in the mouse
    • Hayashi S., McMahon A.P. Efficient recombination in diverse tissues by a tamoxifen-iniducible form of Cre: a tool for temporally regulated Cre activation/inactivation in the mouse. Dev. Biol. 2002, 244:305-318.
    • (2002) Dev. Biol. , vol.244 , pp. 305-318
    • Hayashi, S.1    McMahon, A.P.2
  • 33
    • 0031664399 scopus 로고    scopus 로고
    • Evaluation of dual-energy X-ray absorptiometry for body-composition assessment in rats
    • Bertin E., Ruiz J.C., Mourot J., Peiniau P., Portha B. Evaluation of dual-energy X-ray absorptiometry for body-composition assessment in rats. J. Nutr. 1998, 128:1550-1554.
    • (1998) J. Nutr. , vol.128 , pp. 1550-1554
    • Bertin, E.1    Ruiz, J.C.2    Mourot, J.3    Peiniau, P.4    Portha, B.5
  • 37
    • 0023158563 scopus 로고
    • Inorganic and organic phosphate measurement in the nanomolar range
    • Van Veldhoven P., Mannaerts G. Inorganic and organic phosphate measurement in the nanomolar range. Anal. Biochem. 1987, 161:45-48.
    • (1987) Anal. Biochem. , vol.161 , pp. 45-48
    • Van Veldhoven, P.1    Mannaerts, G.2
  • 38
    • 0021918744 scopus 로고
    • Rapid separation of lipid classes in high yield and purity using bonded phase columns
    • Kaluzny M.A., Duncan L.A., Merritt M.V., Epps D.E. Rapid separation of lipid classes in high yield and purity using bonded phase columns. J. Lipid Res. 1985, 26:135-140.
    • (1985) J. Lipid Res. , vol.26 , pp. 135-140
    • Kaluzny, M.A.1    Duncan, L.A.2    Merritt, M.V.3    Epps, D.E.4
  • 39
    • 0031445663 scopus 로고    scopus 로고
    • Lipase-based quantitation of triacylglycerols in cellular lipid extracts: requirement for presence of detergent and prior separation by thin-layer chromatography
    • Van Veldhoven P.P., Swinnen J.V., Esquenet M., Verhoeven G. Lipase-based quantitation of triacylglycerols in cellular lipid extracts: requirement for presence of detergent and prior separation by thin-layer chromatography. Lipids 1997, 32:1297-1300.
    • (1997) Lipids , vol.32 , pp. 1297-1300
    • Van Veldhoven, P.P.1    Swinnen, J.V.2    Esquenet, M.3    Verhoeven, G.4
  • 40
    • 0002364641 scopus 로고
    • Colorimetric ultramicro method for the determination of free fatty acids
    • NOVAK M. Colorimetric ultramicro method for the determination of free fatty acids. J. Lipid Res. 1965, 6:431-433.
    • (1965) J. Lipid Res. , vol.6 , pp. 431-433
    • Novak, M.1
  • 41
    • 0036217052 scopus 로고    scopus 로고
    • Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes
    • Lewis G.F., Carpentier A., Adeli K., Giacca A. Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes. Endocr. Rev. 2002, 23:201-229.
    • (2002) Endocr. Rev. , vol.23 , pp. 201-229
    • Lewis, G.F.1    Carpentier, A.2    Adeli, K.3    Giacca, A.4
  • 42
    • 58749091645 scopus 로고    scopus 로고
    • UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality
    • Feldmann H.M., Golozoubova V., Cannon B., Nedergaard J. UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality. Cell Metab. 2009, 9:203-209.
    • (2009) Cell Metab. , vol.9 , pp. 203-209
    • Feldmann, H.M.1    Golozoubova, V.2    Cannon, B.3    Nedergaard, J.4
  • 43
    • 0347989317 scopus 로고    scopus 로고
    • Brown adipose tissue: function and physiological significance
    • Cannon B., Nedergaard J. Brown adipose tissue: function and physiological significance. Physiol. Rev. 2004, 84:277-359.
    • (2004) Physiol. Rev. , vol.84 , pp. 277-359
    • Cannon, B.1    Nedergaard, J.2
  • 45
    • 0035088908 scopus 로고    scopus 로고
    • Regulation of leptin production: sympathetic nervous system interactions
    • Rayner D.V., Trayhurn P. Regulation of leptin production: sympathetic nervous system interactions. J. Mol. Med. 2001, 79:8-20.
    • (2001) J. Mol. Med. , vol.79 , pp. 8-20
    • Rayner, D.V.1    Trayhurn, P.2
  • 47
    • 51549107903 scopus 로고    scopus 로고
    • Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism
    • Cao H., Gerhold K., Mayers J.R., Wiest M.M., Watkins S.M., Hotamisligil G.S. Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism. Cell 2008, 134:933-944.
    • (2008) Cell , vol.134 , pp. 933-944
    • Cao, H.1    Gerhold, K.2    Mayers, J.R.3    Wiest, M.M.4    Watkins, S.M.5    Hotamisligil, G.S.6
  • 48
    • 0027443368 scopus 로고
    • Local sympathetic denervation of white adipose tissue in rats induces preadipocyte proliferation without noticeable changes in metabolism
    • Cousin B., Casteilla L., Lafontan M., Ambid L., Langin D., Berthault M.F., Penicaud L. Local sympathetic denervation of white adipose tissue in rats induces preadipocyte proliferation without noticeable changes in metabolism. Endocrinology 1993, 133:2255-2262.
    • (1993) Endocrinology , vol.133 , pp. 2255-2262
    • Cousin, B.1    Casteilla, L.2    Lafontan, M.3    Ambid, L.4    Langin, D.5    Berthault, M.F.6    Penicaud, L.7
  • 49
    • 0030991928 scopus 로고    scopus 로고
    • Thermoregulatory and metabolic phenotypes of mice lacking noradrenaline and adrenaline
    • Thomas S.A., Palmiter R.D. Thermoregulatory and metabolic phenotypes of mice lacking noradrenaline and adrenaline. Nature 1997, 387:94-97.
    • (1997) Nature , vol.387 , pp. 94-97
    • Thomas, S.A.1    Palmiter, R.D.2
  • 50
    • 0042131525 scopus 로고    scopus 로고
    • Inactivation of ether lipid biosynthesis causes male infertility, defects in eye development and optic nerve hypoplasia in mice
    • Rodemer C., Thai T.P., Brugger B., Kaercher T., Werner H., Nave K.-A., Wieland F., Gorgas K., Just W.W. Inactivation of ether lipid biosynthesis causes male infertility, defects in eye development and optic nerve hypoplasia in mice. Hum. Mol. Genet. 2003, 12:1881-1895.
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 1881-1895
    • Rodemer, C.1    Thai, T.P.2    Brugger, B.3    Kaercher, T.4    Werner, H.5    Nave, K.-A.6    Wieland, F.7    Gorgas, K.8    Just, W.W.9
  • 51
    • 0034880780 scopus 로고    scopus 로고
    • The sympathetic nervous system in white adipose tissue regulation
    • Rayner D.V. The sympathetic nervous system in white adipose tissue regulation. Proc. Nutr. Soc. 2001, 60:357-364.
    • (2001) Proc. Nutr. Soc. , vol.60 , pp. 357-364
    • Rayner, D.V.1
  • 53
    • 34548169165 scopus 로고    scopus 로고
    • Thematic review series: adipocyte biology. Sympathetic and sensory innervation of white adipose tissue
    • Bartness T.J., Song C.K. Thematic review series: adipocyte biology. Sympathetic and sensory innervation of white adipose tissue. J. Lipid Res. 2007, 48:1655-1672.
    • (2007) J. Lipid Res. , vol.48 , pp. 1655-1672
    • Bartness, T.J.1    Song, C.K.2
  • 57
    • 33845969892 scopus 로고    scopus 로고
    • UCP1-independent thermogenesis in white adipose tissue of cold-acclimated Ucp1-/- mice
    • Ukropec J., Anunciado R.P., Ravussin Y., Hulver M.W., Kozak L.P. UCP1-independent thermogenesis in white adipose tissue of cold-acclimated Ucp1-/- mice. J. Biol. Chem. 2006, 281:31894-31908.
    • (2006) J. Biol. Chem. , vol.281 , pp. 31894-31908
    • Ukropec, J.1    Anunciado, R.P.2    Ravussin, Y.3    Hulver, M.W.4    Kozak, L.P.5
  • 58
    • 77649106681 scopus 로고    scopus 로고
    • A novel role for beta-adrenoceptor signalling in skeletal muscle growth, development and regeneration
    • Ryall J.G., Church J.E., Lynch G.S. A novel role for beta-adrenoceptor signalling in skeletal muscle growth, development and regeneration. Clin. Exp. Pharmacol. Physiol. 2010, 37:397-401.
    • (2010) Clin. Exp. Pharmacol. Physiol. , vol.37 , pp. 397-401
    • Ryall, J.G.1    Church, J.E.2    Lynch, G.S.3
  • 60
    • 50449102941 scopus 로고    scopus 로고
    • Isoform-specific increases in murine skeletal muscle peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) mRNA in response to beta2-adrenergic receptor activation and exercise
    • Miura S., Kai Y., Kamei Y., Ezaki O. Isoform-specific increases in murine skeletal muscle peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) mRNA in response to beta2-adrenergic receptor activation and exercise. Endocrinology 2008, 149:4527-4533.
    • (2008) Endocrinology , vol.149 , pp. 4527-4533
    • Miura, S.1    Kai, Y.2    Kamei, Y.3    Ezaki, O.4
  • 61
    • 34347237611 scopus 로고    scopus 로고
    • An increase in murine skeletal muscle peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) mRNA in response to exercise is mediated by beta-adrenergic receptor activation
    • Miura S., Kawanaka K., Kai Y., Tamura M., Goto M., Shiuchi T., Minokoshi Y., Ezaki O. An increase in murine skeletal muscle peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) mRNA in response to exercise is mediated by beta-adrenergic receptor activation. Endocrinology 2007, 148:3441-3448.
    • (2007) Endocrinology , vol.148 , pp. 3441-3448
    • Miura, S.1    Kawanaka, K.2    Kai, Y.3    Tamura, M.4    Goto, M.5    Shiuchi, T.6    Minokoshi, Y.7    Ezaki, O.8
  • 62
    • 0024240436 scopus 로고
    • Muscle glycogen utilization during shivering thermogenesis in humans
    • Martineau L., Jacobs I. Muscle glycogen utilization during shivering thermogenesis in humans. J. Appl. Physiol. 1988, 65:2046-2050.
    • (1988) J. Appl. Physiol. , vol.65 , pp. 2046-2050
    • Martineau, L.1    Jacobs, I.2
  • 63
    • 19244386613 scopus 로고
    • Dissociation of sympathetic nervous system and adrenal medullary responses
    • Young J.B., Rosa R.M., Landsberg L. Dissociation of sympathetic nervous system and adrenal medullary responses. Am. J. Physiol. 1984, 247:E35-E40.
    • (1984) Am. J. Physiol. , vol.247
    • Young, J.B.1    Rosa, R.M.2    Landsberg, L.3
  • 65
    • 0028281432 scopus 로고
    • Impaired expression and functional activity of the beta 3- and beta 1-adrenergic receptors in adipose tissue of congenitally obese (C57BL/6J ob/ob) mice
    • Collins S., Daniel K.W., Rohlfs E.M., Ramkumar V., Taylor I.L., Gettys T.W. Impaired expression and functional activity of the beta 3- and beta 1-adrenergic receptors in adipose tissue of congenitally obese (C57BL/6J ob/ob) mice. Mol. Endocrinol. 1994, 8:518-527.
    • (1994) Mol. Endocrinol. , vol.8 , pp. 518-527
    • Collins, S.1    Daniel, K.W.2    Rohlfs, E.M.3    Ramkumar, V.4    Taylor, I.L.5    Gettys, T.W.6


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