메뉴 건너뛰기




Volumn 1781, Issue 11-12, 2008, Pages 694-702

Coordinate induction of PPARα and SREBP2 in multifunctional protein 2 deficient mice

Author keywords

Cholesterol synthesis; Multifunctional protein 2; Peroxisome; PPAR ; SREBP2

Indexed keywords

BILE ACID; CHOLESTEROL; FATTY ACID; GLUCOSE; HIGH DENSITY LIPOPROTEIN; MULTIFUNCTIONAL PROTEIN 2; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 56049092992     PISSN: 13881981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbalip.2008.07.010     Document Type: Article
Times cited : (34)

References (47)
  • 1
    • 4744371532 scopus 로고    scopus 로고
    • Peroxisomes, lipid metabolism, and peroxisomal disorders
    • Wanders R.J. Peroxisomes, lipid metabolism, and peroxisomal disorders. Mol. Genet. Metab. 83 (2004) 16-27
    • (2004) Mol. Genet. Metab. , vol.83 , pp. 16-27
    • Wanders, R.J.1
  • 2
    • 0034939632 scopus 로고    scopus 로고
    • Peroxisomal β-oxidation and peroxisome proliferator-activated receptor α: an adaptive metabolic system
    • Reddy J.K., and Hashimoto T. Peroxisomal β-oxidation and peroxisome proliferator-activated receptor α: an adaptive metabolic system. Annu. Rev. Nutr. 21 (2001) 193-230
    • (2001) Annu. Rev. Nutr. , vol.21 , pp. 193-230
    • Reddy, J.K.1    Hashimoto, T.2
  • 3
    • 2542489070 scopus 로고    scopus 로고
    • Identification of the peroxisomal β-oxidation enzymes involved in the degradation of long-chain dicarboxylic acids
    • Ferdinandusse S., Denis M., van Roermund C.W., Wanders R.J.A., and Dacremont G. Identification of the peroxisomal β-oxidation enzymes involved in the degradation of long-chain dicarboxylic acids. J. Lipid Res. 45 (2004) 1104-1111
    • (2004) J. Lipid Res. , vol.45 , pp. 1104-1111
    • Ferdinandusse, S.1    Denis, M.2    van Roermund, C.W.3    Wanders, R.J.A.4    Dacremont, G.5
  • 5
    • 0034717058 scopus 로고    scopus 로고
    • Inactivation of the peroxisomal multifunctional protein-2 in mice impedes the degradation of not only 2-methyl branched fatty acids and bile acid intermediates but also of very long chain fatty acids
    • Baes M., Huyghe S., Carmeliet P., Declercq P.E., Collen D., Mannaerts G.P., and Van Veldhoven P.P. Inactivation of the peroxisomal multifunctional protein-2 in mice impedes the degradation of not only 2-methyl branched fatty acids and bile acid intermediates but also of very long chain fatty acids. J. Biol. Chem. 275 (2000) 16329-16336
    • (2000) J. Biol. Chem. , vol.275 , pp. 16329-16336
    • Baes, M.1    Huyghe, S.2    Carmeliet, P.3    Declercq, P.E.4    Collen, D.5    Mannaerts, G.P.6    Van Veldhoven, P.P.7
  • 6
    • 33748594955 scopus 로고    scopus 로고
    • Peroxisomal multifunctional protein-2: the enzyme, the patients and the knockout mouse model
    • Huyghe S., Mannaerts G.P., Baes M., and Van Veldhoven P.P. Peroxisomal multifunctional protein-2: the enzyme, the patients and the knockout mouse model. Biochim. Biophys. Acta 1761 (2006) 973-994
    • (2006) Biochim. Biophys. Acta , vol.1761 , pp. 973-994
    • Huyghe, S.1    Mannaerts, G.P.2    Baes, M.3    Van Veldhoven, P.P.4
  • 10
    • 0028997684 scopus 로고
    • Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators
    • Lee S.S., Pineau T., Drago J., Lee E.J., Owens J.W., Kroetz D.L., Fernandez-Salguero P.M., Westphal H., and Gonzalez F.J. Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Mol. Cell. Biol. 15 (1995) 3012-3022
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3012-3022
    • Lee, S.S.1    Pineau, T.2    Drago, J.3    Lee, E.J.4    Owens, J.W.5    Kroetz, D.L.6    Fernandez-Salguero, P.M.7    Westphal, H.8    Gonzalez, F.J.9
  • 12
    • 0036081355 scopus 로고    scopus 로고
    • Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
    • Edgar R., Domrachev M., and Lash A.E. Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res. 30 (2002) 207-210
    • (2002) Nucleic Acids Res. , vol.30 , pp. 207-210
    • Edgar, R.1    Domrachev, M.2    Lash, A.E.3
  • 13
    • 0030305457 scopus 로고    scopus 로고
    • R: a language for data analysis and graphics
    • Ihaka R., and Gentleman R. R: a language for data analysis and graphics. J. Comput. Graph. Stat. 3 (1996) 299314
    • (1996) J. Comput. Graph. Stat. , vol.3 , pp. 299314
    • Ihaka, R.1    Gentleman, R.2
  • 15
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh E.G., and Dyer W.J. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37 (1959) 911-917
    • (1959) Can. J. Biochem. Physiol. , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 16
    • 0032502911 scopus 로고    scopus 로고
    • Enzymatic quantitation of cholesterol esters in lipid extracts
    • Van Veldhoven P.P., Meyhi E., and Mannaerts G.P. Enzymatic quantitation of cholesterol esters in lipid extracts. Anal. Biochem. 258 (1998) 152-155
    • (1998) Anal. Biochem. , vol.258 , pp. 152-155
    • Van Veldhoven, P.P.1    Meyhi, E.2    Mannaerts, G.P.3
  • 17
    • 39749108962 scopus 로고    scopus 로고
    • Meta-analysis of primary target genes of peroxisome proliferator-activated receptors
    • Heinäniemi M., Uski J.O., Degenhardt T., and Carlberg C. Meta-analysis of primary target genes of peroxisome proliferator-activated receptors. Genome Biol. 8 (2007) R147
    • (2007) Genome Biol. , vol.8
    • Heinäniemi, M.1    Uski, J.O.2    Degenhardt, T.3    Carlberg, C.4
  • 19
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: a practical and powerful approach to multiple testing
    • Benjamini Y., and Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J. Royal Stat. Society B 57 (1995) 289-300
    • (1995) J. Royal Stat. Society B , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 20
    • 0033982936 scopus 로고    scopus 로고
    • KEGG: kyoto encyclopedia of genes and genomes
    • Kanehisa M., and Goto S. KEGG: kyoto encyclopedia of genes and genomes. Nucleic Acids Res. 28 (2000) 27-30
    • (2000) Nucleic Acids Res. , vol.28 , pp. 27-30
    • Kanehisa, M.1    Goto, S.2
  • 21
    • 1542283630 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha target genes
    • Mandard S., Muller M., and Kersten S. Peroxisome proliferator-activated receptor alpha target genes. Cell Mol. Life Sci. 61 (2004) 393-416
    • (2004) Cell Mol. Life Sci. , vol.61 , pp. 393-416
    • Mandard, S.1    Muller, M.2    Kersten, S.3
  • 22
    • 0025806284 scopus 로고
    • Superfamily of steroid nuclear receptors: positive and negative regulators of gene expression
    • Wahli W., and Martinez E. Superfamily of steroid nuclear receptors: positive and negative regulators of gene expression. FASEB J. 5 (1991) 2243-2249
    • (1991) FASEB J. , vol.5 , pp. 2243-2249
    • Wahli, W.1    Martinez, E.2
  • 23
    • 0036251153 scopus 로고    scopus 로고
    • SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver
    • Horton J.D., Goldstein J.L., and Brown M.S. SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J. Clin. Invest. 109 (2002) 1125-1131
    • (2002) J. Clin. Invest. , vol.109 , pp. 1125-1131
    • Horton, J.D.1    Goldstein, J.L.2    Brown, M.S.3
  • 24
    • 33645731353 scopus 로고    scopus 로고
    • SREBPs: sterol-regulated transcription factors
    • Espenshade P.J. SREBPs: sterol-regulated transcription factors. J. Cell Sci. 119 (2006) 973-976
    • (2006) J. Cell Sci. , vol.119 , pp. 973-976
    • Espenshade, P.J.1
  • 25
    • 0037040184 scopus 로고    scopus 로고
    • Control of cholesterol turnover in the mouse
    • Dietschy J.M., and Turley S.D. Control of cholesterol turnover in the mouse. J. Biol. Chem. 277 (2002) 3801-3804
    • (2002) J. Biol. Chem. , vol.277 , pp. 3801-3804
    • Dietschy, J.M.1    Turley, S.D.2
  • 26
    • 0036012793 scopus 로고    scopus 로고
    • Nuclear hormone receptors and cholesterol trafficking: the orphans find a new home
    • Fitzgerald M.L., Moore K.J., and Freeman M.W. Nuclear hormone receptors and cholesterol trafficking: the orphans find a new home. J. Mol. Med. 80 (2002) 271-281
    • (2002) J. Mol. Med. , vol.80 , pp. 271-281
    • Fitzgerald, M.L.1    Moore, K.J.2    Freeman, M.W.3
  • 27
    • 10744224980 scopus 로고    scopus 로고
    • Overexpression of peroxisome proliferator-activated receptor-alpha (PPARalpha)-regulated genes in liver in the absence of peroxisome proliferation in mice deficient in both L- and D-forms of enoyl-CoA hydratase/dehydrogenase enzymes of peroxisomal beta-oxidation system
    • Jia Y., Qi C., Zhang Z., Hashimoto T., Rao M.S., Huyghe S., Suzuki Y., Van Veldhoven P.P., Baes M., and Reddy J.K. Overexpression of peroxisome proliferator-activated receptor-alpha (PPARalpha)-regulated genes in liver in the absence of peroxisome proliferation in mice deficient in both L- and D-forms of enoyl-CoA hydratase/dehydrogenase enzymes of peroxisomal beta-oxidation system. J. Biol. Chem. 278 (2003) 47232-47239
    • (2003) J. Biol. Chem. , vol.278 , pp. 47232-47239
    • Jia, Y.1    Qi, C.2    Zhang, Z.3    Hashimoto, T.4    Rao, M.S.5    Huyghe, S.6    Suzuki, Y.7    Van Veldhoven, P.P.8    Baes, M.9    Reddy, J.K.10
  • 30
    • 0033613869 scopus 로고    scopus 로고
    • Phytanic acid activates the peroxisome proliferator-activated receptor α (PPARα) in sterol carrier protein 2-/sterol carrier protein x-deficient mice
    • Ellinghaus P., Wolfrum C., Assmann G., Spener F., and Seedorf U. Phytanic acid activates the peroxisome proliferator-activated receptor α (PPARα) in sterol carrier protein 2-/sterol carrier protein x-deficient mice. J. Biol. Chem. 274 (1999) 2766-2772
    • (1999) J. Biol. Chem. , vol.274 , pp. 2766-2772
    • Ellinghaus, P.1    Wolfrum, C.2    Assmann, G.3    Spener, F.4    Seedorf, U.5
  • 32
    • 0033739281 scopus 로고    scopus 로고
    • Pristanic acid and phytanic acid: naturally occurring ligands for the nuclear receptor peroxisome proliferator-activated receptor a
    • Zomer A.W.M., van der Burg B., Jansen G.A., Wanders R.J.A., Poll-The B.T., and van der Saag P.T. Pristanic acid and phytanic acid: naturally occurring ligands for the nuclear receptor peroxisome proliferator-activated receptor a. J. Lipid Res. 41 (2000) 1801-1807
    • (2000) J. Lipid Res. , vol.41 , pp. 1801-1807
    • Zomer, A.W.M.1    van der Burg, B.2    Jansen, G.A.3    Wanders, R.J.A.4    Poll-The, B.T.5    van der Saag, P.T.6
  • 34
    • 0036582710 scopus 로고    scopus 로고
    • Phytanic acid, a natural peroxisome proliferator-activated receptor agonist, regulates glucose metabolism in rat primary hepatocytes
    • Heim M., Johnson J., Boess F., Bendik I., Weber P., Hunziker W., and Flühmann B. Phytanic acid, a natural peroxisome proliferator-activated receptor agonist, regulates glucose metabolism in rat primary hepatocytes. FASEB J. 16 (2002) 718-720
    • (2002) FASEB J. , vol.16 , pp. 718-720
    • Heim, M.1    Johnson, J.2    Boess, F.3    Bendik, I.4    Weber, P.5    Hunziker, W.6    Flühmann, B.7
  • 35
    • 0035065450 scopus 로고    scopus 로고
    • Disturbances in the normal regulation of SREBP-sensitive genes in PPAR alpha-deficient mice
    • Patel D.D., Knight B.L., Wiggins D., Humphreys S.M., and Gibbons G.F. Disturbances in the normal regulation of SREBP-sensitive genes in PPAR alpha-deficient mice. J. Lipid Res. 42 (2001) 328-337
    • (2001) J. Lipid Res. , vol.42 , pp. 328-337
    • Patel, D.D.1    Knight, B.L.2    Wiggins, D.3    Humphreys, S.M.4    Gibbons, G.F.5
  • 36
    • 0034658445 scopus 로고    scopus 로고
    • Changes in isoprenoid lipid synthesis by gemfibrozil and clofibric acid in rat hepatocytes
    • Hashimoto F., Taira S., and Hayashi H. Changes in isoprenoid lipid synthesis by gemfibrozil and clofibric acid in rat hepatocytes. Biochem. Pharmacol. 59 (2000) 1203-1210
    • (2000) Biochem. Pharmacol. , vol.59 , pp. 1203-1210
    • Hashimoto, F.1    Taira, S.2    Hayashi, H.3
  • 38
    • 0141703318 scopus 로고    scopus 로고
    • Effects of peroxisome proliferators gemfibrozil and clofibrate on syntheses of dolichol and cholesterol in rat liver
    • Shiota Y., Ikeda M., Hashimoto F., and Hayashi H. Effects of peroxisome proliferators gemfibrozil and clofibrate on syntheses of dolichol and cholesterol in rat liver. J. Biochem. 134 (2003) 197-202
    • (2003) J. Biochem. , vol.134 , pp. 197-202
    • Shiota, Y.1    Ikeda, M.2    Hashimoto, F.3    Hayashi, H.4
  • 39
    • 3042519202 scopus 로고    scopus 로고
    • Effects of peroxisome proliferator-activated receptor alpha activation on pathways contributing to cholesterol homeostasis in rat hepatocytes
    • Le Jossic-Corcos C., Duclos S., Ramirez L.C., Zaghini I., Chevillard G., Martin P., Pineau T., and Bournot P. Effects of peroxisome proliferator-activated receptor alpha activation on pathways contributing to cholesterol homeostasis in rat hepatocytes. Biochim. Biophys. Acta 1683 (2004) 49-58
    • (2004) Biochim. Biophys. Acta , vol.1683 , pp. 49-58
    • Le Jossic-Corcos, C.1    Duclos, S.2    Ramirez, L.C.3    Zaghini, I.4    Chevillard, G.5    Martin, P.6    Pineau, T.7    Bournot, P.8
  • 41
    • 0036018142 scopus 로고    scopus 로고
    • Central role of peroxisomes in isoprenoid biosynthesis
    • Kovacs W.J., Olivier L.M., and Krisans S.K. Central role of peroxisomes in isoprenoid biosynthesis. Prog. Lipid Res. 41 (2002) 369-391
    • (2002) Prog. Lipid Res. , vol.41 , pp. 369-391
    • Kovacs, W.J.1    Olivier, L.M.2    Krisans, S.K.3
  • 42
    • 1542329066 scopus 로고    scopus 로고
    • Cholesterol biosynthesis and regulation: role of peroxisomes
    • Kovacs W.J., and Krisans S. Cholesterol biosynthesis and regulation: role of peroxisomes. Adv. Exp. Med. Biol. 544 (2003) 315-327
    • (2003) Adv. Exp. Med. Biol. , vol.544 , pp. 315-327
    • Kovacs, W.J.1    Krisans, S.2
  • 43
  • 46
    • 0036021212 scopus 로고    scopus 로고
    • Profiling of acyl-CoA oxidase-deficient and peroxisome proliferator Wy14,643-treated mouse liver protein by surface-enhanced laser desorption/ionization ProteinChip Biology System
    • Chu R., Zhang W., Lim H., Yeldandi A.V., Herring C., Brumfield L., Reddy J.K., and Davison M. Profiling of acyl-CoA oxidase-deficient and peroxisome proliferator Wy14,643-treated mouse liver protein by surface-enhanced laser desorption/ionization ProteinChip Biology System. Gene Expr. 10 (2002) 165-177
    • (2002) Gene Expr. , vol.10 , pp. 165-177
    • Chu, R.1    Zhang, W.2    Lim, H.3    Yeldandi, A.V.4    Herring, C.5    Brumfield, L.6    Reddy, J.K.7    Davison, M.8
  • 47
    • 0031705644 scopus 로고    scopus 로고
    • Marked reduction in bile acid synthesis in cholesterol 7α-hydroxylase-deficient mice does not lead to diminished tissue cholesterol turnover or to hypercholesterolemia
    • Schwarz M., Russell D.W., Dietschy J.M., and Turley S.D. Marked reduction in bile acid synthesis in cholesterol 7α-hydroxylase-deficient mice does not lead to diminished tissue cholesterol turnover or to hypercholesterolemia. J. Lipid Res. 39 (1998) 1833-1843
    • (1998) J. Lipid Res. , vol.39 , pp. 1833-1843
    • Schwarz, M.1    Russell, D.W.2    Dietschy, J.M.3    Turley, S.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.