Effects of chronic guanosine treatment on hippocampal damage and cognitive impairment of rats submitted to chronic cerebral hypoperfusion

Neurological Sciences

Volumn 33, Issue 5, 2012, Pages 985-997

  Ganzella, Marcelo ^a   De Oliveira, Enderson Dias Alves ^a   Comassetto, Daniel Diniz ^a   Cechetti, Fernanda ^a   Cereser, Victor Hermes ^a   Moreira, Júlia Dubois ^a   Hansel, Gisele ^a   Almeida, Roberto Farina ^a   Ramos, Denise Barbosa ^a   Figueredo, Yanier Nuñes ^b   Souza, Debora Guerini ^a   Oses, Jean Pierre ^a,c   Worm, Paulo Valdeci ^a   Achaval, Matilde ^a   Netto, Carlos Alexandre ^a   Souza, Diogo Onofre ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b CENTRO DE INVESTIGACIÓN Y DESARROLLO DE MEDICAMENTOS CIDEM   (Cuba)

^c CATHOLIC UNIVERSITY OF PELOTAS   (Brazil)

Author keywords

Cerebral hypoperfusion; Cognitive impairment; Guanosine; Hippocampal damage; Neuroprotection

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; GUANOSINE; PROTEIN S100B; PURINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; CAROTID ARTERY OBSTRUCTION; CELL LABELING; CEREBRAL HYPOPERFUSION; CEREBROSPINAL FLUID LEVEL; CEREBROVASCULAR DISEASE; CHRONIC DRUG ADMINISTRATION; COGNITIVE DEFECT; CONTROLLED STUDY; GLIA CELL; HIPPOCAMPAL CA1 REGION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; MALE; MAZE TEST; MENTAL TASK; NEUROPROTECTION; NONHUMAN; PROTEIN BLOOD LEVEL; PYRAMIDAL NERVE CELL; RAT; SPATIAL MEMORY; TREATMENT OUTCOME;

ANIMALS; BRAIN ISCHEMIA; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COGNITION; COGNITION DISORDERS; GUANOSINE; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; MAZE LEARNING; NEUROPROTECTIVE AGENTS; PURINES; RATS; RATS, WISTAR;

EID: 84869228041     PISSN: 15901874     EISSN: 15903478     Source Type: Journal    
DOI: 10.1007/s10072-011-0872-1     Document Type: Article

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