Increased plasma levels of brain derived neurotrophic factor (BDNF) in patients with fibromyalgia

Neurochemical Research

Volumn 35, Issue 5, 2010, Pages 830-834

  Haas, Lisete ^a   Portela, Luis V C ^b   Böhmer, Ana Elisa ^b   Oses, Jean Pierre ^c   Lara, Diogo R ^a  

^a PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b Instituto de Ciencias Biologicas e da Saude Pontifical Catholic University of Minas Gerais   (Brazil)

^c CATHOLIC UNIVERSITY OF PELOTAS   (Brazil)

Author keywords

Antidepressant; BDNF; Depression; Fibromyalgia; Pain

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR;

ADULT; AGE; ARTICLE; BLOOD ANALYSIS; CLINICAL ARTICLE; CONTROLLED STUDY; DEPRESSION; DISEASE DURATION; ENZYME IMMUNOASSAY; FEMALE; FIBROMYALGIA; HAMILTON SCALE; HUMAN; PAIN ASSESSMENT; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL;

EID: 77953286313     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-010-0129-z     Document Type: Article

References (29)

1. Mease P (2005) Fibromyalgia syndrome: review of clinical presentation, pathogenesis, outcome measures, and treatment. J Rheumatol Suppl 75:6-21
2. Gran JT (2003) The epidemiology of chronic generalized musculoskeletal pain. Best Pract Res Clin Rheumatol 17:547-561
3. Katz RS, Wolfe F, Michaud K (2006) Fibromyalgia diagnosis: a comparison of clinical, survey, and American College of Rheumatology criteria. Arthritis Rheum 54:169-176
4. Meeus M, Nijs J (2007) Central sensitization: a biopsychosocial explanation for chronic widespread pain in patients with fibromyalgia and chronic fatigue syndrome. Clin Rheumatol 26: 465-473
5. Schwarz MJ, Spath M, Muller-Bardorff H (1999) Relationship of substance P, 5-hydroxyindole acetic acid and tryptophan in serum of fibromyalgia patients. Neurosci Lett 259:196-198
6. Julien N, Goffaux P, Arsenault P (2005) Widespread pain in fibromyalgia is related to a deficit of endogenous pain inhibition. Pain 114:295-302
7. Kassam A, Patten SB (2006) Major depression, fibromyalgia and labour force participation: a population-based cross-sectional study. BMC Musculoskelet Disord 7:4
8. Laske C, Stransky E, Eschweiler GW (2007) Increased BDNF serum concentration in fibromyalgia with or without depression or antidepressants. J Psychiatr Res 41:600-605
9. Suhr JA (2003) Neuropsychological impairment in fibromyalgia: relation to depression, fatigue, and pain. J Psychosom Res 55:321-329
10. Wu YJ, Kruttgen A, Moller JC, Len G, McAuliffe G, Ma C, Tai JP, Xu F (2004) Nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 are sorted to dense-core vesicles and released via the regulated pathway in primary rat cortical neurons. J Neurosci Res 75:825-834
11. Malcangio M, Lessmann V (2003) A common thread for pain and memory synapses? Brain-derived neurotrophic factor and trkB receptors. Trends Pharmacol Sci 24:116-121
12. Delafoy L, Gelot A, Ardid D (2006) Interactive involvement of brain derived neurotrophic factor, nerve growth factor, and calcitonin gene related peptide in colonic hypersensitivity in the rat. Gut 55:940-945
13. Groth R, Aanonsen L (2002) Spinal brain-derived neurotrophic factor (BDNF) produces hyperalgesia in normal mice while antisense directed against either BDNF or trkB, prevent inflammation- induced hyperalgesia. Pain 100:171-181
14. Wu K, Len GW, McAuliffe G (2004) Brain-derived neurotrophic factor acutely enhances tyrosine phosphorylation of the AMPA receptor subunit GluR1 via NMDA receptor-dependent mechanisms. Brain Res Mol Brain Res 130:178-186
15. Yoshimura R, Mitoma M, Sugita A et al (2007) Effects of paroxetine or milnacipran on serum brain-derived neurotrophic factor in depressed patients. Prog Neuropsychopharmacol Biol Psychiatry 31:1034-1037
16. Karege F, Perret G, Bondolfi G (2002) Decreased serum brainderived neurotrophic factor levels in major depressed patients. Psychiatry Res 109:143-148
17. Aydemir O, Deveci A, Taneli F (2005) The effect of chronic antidepressant treatment on serum brain-derived neurotrophic factor levels in depressed patients: a preliminary study. Prog Neuropsychopharmacol Biol Psychiatry 29:261-265
18. Shimizu E, Hashimoto K, Okamura N, Koike K, Komatsu N, Kumakiri C, Nakazato M, Watanabe H, Shinoda N, Okada S, Iyo M (2003) Alterations of serum levels of brain-derived neurotrophic factor (BDNF) in depressed patients with or without antidepressants. Biol Psychiatry 54:70-75 (Pubitemid 36776725)
19. Piccinni A, Marazziti D, Catena M et al (2007) Plasma and serum brain-derived neurotrophic factor (BDNF) in depressed patients during 1 year of antidepressant treatments. J Affect Disord 105:279-283
20. Chen B, Dowlatshahi D, MacQueen GM (2001) Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication. Biol Psychiatry 50:260-265
21. Sarchielli P, Mancini ML, Floridi A et al (2007) Increased levels of neurotrophins are not specific for chronic migraine: evidence from primary fibromyalgia syndrome. J Pain 8:737-745
22. Hamilton M (1960) A rating scale for depression. J Neurol Neurosurg Psychiatry 23:56-62
23. Duric V, McCarson KE (2006) Effects of analgesic or antidepressant drugs on pain- or stress-evoked hippocampal and spinal neurokinin-1 receptor and brain-derived neurotrophic factor gene expression in the rat. J Pharmacol Exp Ther 319:1235-1243
24. Duric V, McCarson KE (2006) Persistent pain produces stresslike alterations in hippocampal neurogenesis and gene expression. J Pain 7:544-555
25. Nibuya M, Morinobu S, Duman RS (1995) Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments. J Neurosci 15:7539-7547
26. Lee J, Duan W, Mattson MP (2002) Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice. J Neurochem 82:1367-1375
27. Sairanen M, Lucas G, Ernfors P (2005) Brain-derived neurotrophic factor and antidepressant drugs have different but coordinated effects on neuronal turnover, proliferation, and survival in the adult dentate gyrus. J Neurosci 25:1089-1094
28. Pezet S, Cunningham J, Patel J (2002) BDNF modulates sensory neuron synaptic activity by a facilitation of GABA transmission in the dorsal horn. Mol Cell Neurosci 21:51-62
29. Pezet S, Malcangio M, Lever IJ (2002) Noxious stimulation induces Trk receptor and downstream ERK phosphorylation in spinal dorsal horn. Mol Cell Neurosci 21:684-695