Identification and functional characterization of a novel UDP-glucuronosyltransferase 2A1 splice variant: Potential importance in tobacco-related cancer susceptibility

Journal of Pharmacology and Experimental Therapeutics

Volumn 343, Issue 3, 2012, Pages 713-724

  Bushey, Ryan T ^a   Lazarus, Philip ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 HYDROXYPYRENE; 3 HYDROXYBENZO[A]PYRENE; 7,8 DIHYDRO 7,8 DIHYDROXYBENZO[A]PYRENE; GLUCURONOSYLTRANSFERASE; GLUCURONOSYLTRANSFERASE 1A10; GLUCURONOSYLTRANSFERASE 1A7; GLUCURONOSYLTRANSFERASE 2A1 I1 SPLICE VARIANT; GLUCURONOSYLTRANSFERASE 2A1 I2 SPLICE VARIANT; MESSENGER RNA; UNCLASSIFIED DRUG; CARCINOGEN; GLUCURONIDE; ISOPROTEIN; POLYCYCLIC AROMATIC HYDROCARBON; UGT2A1 PROTEIN, HUMAN;

ARTICLE; CANCER SUSCEPTIBILITY; CELL STRAIN HEK293; CHEMICAL CARCINOGENESIS; COLON; CONTROLLED STUDY; DISEASE ASSOCIATION; EMBRYO; ENZYME ACTIVITY; ENZYME INHIBITION; EXON; GLUCURONIDATION; HETERO OLIGOMERIZATION; HOMO OLIGOMERIZATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOPRECIPITATION; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; LUNG; NUCLEOTIDE SEQUENCE; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TOBACCO CARCINOGENESIS; ULTRA PRESSURE LIQUID CHROMATOGRAPHY; ALTERNATIVE RNA SPLICING; ANTIBODY SPECIFICITY; CHEMICALLY INDUCED DISORDER; DISEASE PREDISPOSITION; ENZYMOLOGY; GENETICS; METABOLISM; NEOPLASM; PHYSIOLOGY; TOBACCO; WESTERN BLOTTING;

ALTERNATIVE SPLICING; BLOTTING, WESTERN; CARCINOGENS; DISEASE SUSCEPTIBILITY; EXONS; GLUCURONIDES; GLUCURONOSYLTRANSFERASE; HEK293 CELLS; HUMANS; NEOPLASMS; ORGAN SPECIFICITY; POLYCYCLIC HYDROCARBONS, AROMATIC; PROTEIN ISOFORMS; REAL-TIME POLYMERASE CHAIN REACTION; TOBACCO;

EID: 84869208721     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.112198770     Document Type: Article

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