-
1
-
-
34548680964
-
Plasma level and tissue expression of vascular endothelial growth factor in renal cell carcinoma: A prospective study of 50 cases
-
DOI 10.1016/j.humpath.2007.02.014, PII S0046817707001037
-
Rioux-Leclercq, N. et al. Plasma level and tissue expression of vascular endothelial growth factor in renal cell carcinoma: a prospective study of 50 cases. Hum Pathol 38, 1489-1495 (2007). (Pubitemid 47418959)
-
(2007)
Human Pathology
, vol.38
, Issue.10
, pp. 1489-1495
-
-
Rioux-Leclercq, N.1
Fergelot, P.2
Zerrouki, S.3
Leray, E.4
Jouan, F.5
Bellaud, P.6
Epstein, J.I.7
Patard, J.-J.8
-
2
-
-
34848898470
-
Hypoxia-inducible factors and cancer
-
Calzada, M. J. & del Peso, L. Hypoxia-inducible factors and cancer. Clin Transl Oncol 9, 278-289 (2007).
-
(2007)
Clin Transl Oncol
, vol.9
, pp. 278-289
-
-
Calzada, M.J.1
Del Peso, L.2
-
3
-
-
0035834409
-
A conserved family of prolyl-4-hydroxylases that modify HIF
-
DOI 10.1126/science.1066373
-
Bruick, R. K. &McKnight, S. L. A conserved family of prolyl-4-hydroxylases that modify HIF. Science 294, 1337-1340 (2001). (Pubitemid 33063099)
-
(2001)
Science
, vol.294
, Issue.5545
, pp. 1337-1340
-
-
Bruick, R.K.1
McKnight, S.L.2
-
4
-
-
17944375360
-
C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
-
DOI 10.1016/S0092-8674(01)00507-4
-
Epstein, A. C. et al. C. elegans EGL-9 andmammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. Cell 107, 43-54 (2001). (Pubitemid 32972036)
-
(2001)
Cell
, vol.107
, Issue.1
, pp. 43-54
-
-
Epstein, A.C.R.1
Gleadle, J.M.2
McNeill, L.A.3
Hewitson, K.S.4
O'Rourke, J.5
Mole, D.R.6
Mukherji, M.7
Metzen, E.8
Wilson, M.I.9
Dhanda, A.10
Tian, Y.-M.11
Masson, N.12
Hamilton, D.L.13
Jaakkola, P.14
Barstead, R.15
Hodgkin, J.16
Maxwell, P.H.17
Pugh, C.W.18
Schofield, C.J.19
Ratcliffe, P.J.20
more..
-
5
-
-
0035917313
-
2 sensing
-
Ivan, M. et al. HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing. Science. 292, 464-468 (2001). (Pubitemid 32335941)
-
(2001)
Science
, vol.292
, Issue.5516
, pp. 464-468
-
-
Ivan, M.1
Kondo, K.2
Yang, H.3
Kim, W.4
Valiando, J.5
Ohh, M.6
Salic, A.7
Asara, J.M.8
Lane, W.S.9
Kaelin Jr., W.G.10
-
6
-
-
0035917808
-
2-regulated prolyl hydroxylation
-
Jaakkola, P. et al. Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. Science. 292, 468-472 (2001). (Pubitemid 32335942)
-
(2001)
Science
, vol.292
, Issue.5516
, pp. 468-472
-
-
Jaakkola, P.1
Mole, D.R.2
Tian, Y.-M.3
Wilson, M.I.4
Gielbert, J.5
Gaskell, S.J.6
Von Kriegsheim, A.7
Hebestreit, H.F.8
Mukherji, M.9
Schofield, C.J.10
Maxwell, P.H.11
Pugh, C.W.12
Ratcliffe, P.J.13
-
7
-
-
67650531089
-
Genome-wide association of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxiainducible transcripts
-
Mole, D. R. et al. Genome-wide association of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxiainducible transcripts. J Biol Chem 284, 16767-16775 (2009).
-
(2009)
J Biol Chem
, vol.284
, pp. 16767-16775
-
-
Mole, D.R.1
-
8
-
-
77952300971
-
Genomewide identification of hypoxia-inducible factor binding sites and target genes by a probabilistic model integrating transcription-profiling data and in silico binding site prediction
-
Ortiz-Barahona, A., Villar, D., Pescador, N., Amigo, J. & del Peso, L. Genomewide identification of hypoxia-inducible factor binding sites and target genes by a probabilistic model integrating transcription-profiling data and in silico binding site prediction. Nucleic Acids Res 38, 2332-2345 (2010).
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 2332-2345
-
-
Ortiz-Barahona, A.1
Villar, D.2
Pescador, N.3
Amigo, J.4
Del Peso, L.5
-
9
-
-
77952510108
-
Hypoxia-regulated angiogenic inhibitors
-
Messmer-Blust, A., An, X. & Li, J. Hypoxia-regulated angiogenic inhibitors. Trends Cardiovasc Med 19, 252-256 (2009).
-
(2009)
Trends Cardiovasc Med
, vol.19
, pp. 252-256
-
-
Messmer-Blust, A.1
An, X.2
Li, J.3
-
10
-
-
0025147371
-
A tumour suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin
-
Good, D. J. et al. A tumour suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin. Proc Natl Acad Sci USA 87, 6624-6628 (1990).
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 6624-6628
-
-
Good, D.J.1
-
11
-
-
0036362236
-
Thrombospondin-1 as an endogenous inhibitor of angiogenesis and tumor growth
-
Lawler, J. Thrombospondin-1 as an endogenous inhibitor of angiogenesis and tumour growth. J Cell Mol Med 6, 1-12 (2002). (Pubitemid 44133979)
-
(2002)
Journal of Cellular and Molecular Medicine
, vol.6
, Issue.1
, pp. 1-12
-
-
Lawler, J.1
-
12
-
-
0035049231
-
Thrombospondins as matricellular modulators of cell function
-
Bornstein, P. Thrombospondins as matricellular modulators of cell function. J Clin Invest 107, 929-934 (2001). (Pubitemid 32323400)
-
(2001)
Journal of Clinical Investigation
, vol.107
, Issue.8
, pp. 929-934
-
-
Bornstein, P.1
-
14
-
-
0026006134
-
Antisense-mediated reduction in thrombospondin reverses the malignant phenotype of a human squamous carcinoma
-
Castle, V., Varani, J., Fligiel, S., Prochownik, E. V. & Dixit, V. Antisense-mediated reduction in thrombospondin reverses the malignant phenotype of a human squamous carcinoma. J Clin Invest 87, 1883-1888 (1991).
-
(1991)
J Clin Invest
, vol.87
, pp. 1883-1888
-
-
Castle, V.1
Varani, J.2
Fligiel, S.3
Prochownik, E.V.4
Dixit, V.5
-
15
-
-
0023270616
-
Thrombospondin, a potentiator of tumor cell metastasis
-
Tuszynski, G. P., Gasic, T. B., Rothman, V. L., Knudsen, K. A. & Gasic, G. J. Thrombospondin, a potentiator of tumour cell metastasis. Cancer Res 47, 4130-4133 (1987). (Pubitemid 17108482)
-
(1987)
Cancer Research
, vol.47
, Issue.15
, pp. 4130-4133
-
-
Tuszynski, G.P.1
Gasic, T.B.2
Rothman, V.L.3
-
16
-
-
0026570066
-
Biological activities of peptides and peptide analogues derived from common sequences present in thrombospondin, properdin, and malarial proteins
-
Tuszynski, G. P., Rothman, V. L., Deutch, A. H., Hamilton, B. K. & Eyal, J. Biological activities of peptides and peptide analogues derived from common sequences present in thrombospondin, properdin, and malarial proteins. J Cell Biol 116, 209-217 (1992).
-
(1992)
J Cell Biol
, vol.116
, pp. 209-217
-
-
Tuszynski, G.P.1
Rothman, V.L.2
Deutch, A.H.3
Hamilton, B.K.4
Eyal, J.5
-
18
-
-
3242772439
-
The thrombospondin type 1 repeat superfamily
-
DOI 10.1016/j.biocel.2003.12.011, PII S135727250300428X
-
Tucker, R. P. The thrombospondin type 1 repeat superfamily. Int J Biochem Cell Biol 36, 969-974 (2004). (Pubitemid 38501547)
-
(2004)
International Journal of Biochemistry and Cell Biology
, vol.36
, Issue.6
, pp. 969-974
-
-
Tucker, R.P.1
-
19
-
-
52049083001
-
Thrombospondin 1 promotes tumour macrophage recruitment and enhances tumour cell cytotoxicity of differentiated U937 cells
-
Martin-Manso, G. et al. Thrombospondin 1 promotes tumour macrophage recruitment and enhances tumour cell cytotoxicity of differentiated U937 cells. Cancer Res 68, 7090-7099 (2008).
-
(2008)
Cancer Res
, vol.68
, pp. 7090-7099
-
-
Martin-Manso, G.1
-
20
-
-
48249107523
-
Thrombospondin 1 and vasoactive agents indirectly alter tumour blood flow
-
Isenberg, J. S. et al. Thrombospondin 1 and vasoactive agents indirectly alter tumour blood flow. Neoplasia 10, 886-896 (2008).
-
(2008)
Neoplasia
, vol.10
, pp. 886-896
-
-
Isenberg, J.S.1
-
21
-
-
0028672529
-
The p53 tumour suppressor gene inhibits angiogenesis by stimulating the production of thrombospondin
-
Dameron, K. M., Volpert, O. V., Tainsky, M. A. & Bouck, N. The p53 tumour suppressor gene inhibits angiogenesis by stimulating the production of thrombospondin. Cold Spring Harb Symp Quant Biol 59, 483-489 (1994).
-
(1994)
Cold Spring Harb Symp Quant Biol
, vol.59
, pp. 483-489
-
-
Dameron, K.M.1
Volpert, O.V.2
Tainsky, M.A.3
Bouck, N.4
-
22
-
-
0035836627
-
PTEN controls tumour-induced angiogenesis
-
Wen, S. et al. PTEN controls tumour-induced angiogenesis. Proc Natl Acad Sci USA 98, 4622-4627 (2001).
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 4622-4627
-
-
Wen, S.1
-
23
-
-
0034209874
-
Activation of the Myc oncoprotein leads to increased turnover of thrombospondin-1 mRNA
-
Janz, A., Sevignani, C., Kenyon, K., Ngo, C. V. & Thomas-Tikhonenko, A. Activation of the myc oncoprotein leads to increased turnover of thrombospondin-1 mRNA. Nucleic Acids Res 28, 2268-2275 (2000). (Pubitemid 30639360)
-
(2000)
Nucleic Acids Research
, vol.28
, Issue.11
, pp. 2268-2275
-
-
Janz, A.1
Sevignani, C.2
Kenyon, K.3
Ngo, C.V.4
Thomas-Tikhonenko, A.5
-
24
-
-
0028138632
-
SPARC and thrombospondin genes are repressed by the c-jun oncogene in rat embryo fibroblasts
-
Mettouchi, A. et al. SPARC and thrombospondin genes are repressed by the c-jun oncogene in rat embryo fibroblasts. EMBO J 13, 5668-5678 (1994). (Pubitemid 24363035)
-
(1994)
EMBO Journal
, vol.13
, Issue.23
, pp. 5668-5678
-
-
Mettouchi, A.1
Cabon, F.2
Montreau, N.3
Vernier, P.4
Mercier, G.5
Blangy, D.6
Tricoire, H.7
Vigier, P.8
Binetruy, B.9
-
25
-
-
0028037536
-
Transformation by v-src causes transient induction followed by repression of mouse thrombospondin-1
-
Slack, J. L. & Bornstein, P. Transformation by v-src causes transient induction followed by repression of mouse thrombospondin-1. Cell Growth Differ 5, 1373-1380 (1994). (Pubitemid 24381526)
-
(1994)
Cell Growth and Differentiation
, vol.5
, Issue.12
, pp. 1373-1380
-
-
Slack, J.L.1
Bornstein, P.2
-
26
-
-
19044388761
-
Id1 regulates angiogenesis through transcriptional repression of thrombospondin-1
-
DOI 10.1016/S1535-6108(02)00209-X
-
Volpert, O. V. et al. Id1 regulates angiogenesis through transcriptional repression of thrombospondin-1. Cancer Cell. 2, 473-483 (2002). (Pubitemid 41043952)
-
(2002)
Cancer Cell
, vol.2
, Issue.6
, pp. 473-483
-
-
Volpert, O.V.1
Pili, R.2
Sikder, H.A.3
Nelius, T.4
Zaichuk, T.5
Morris, C.6
Shiflett, C.B.7
Devlin, M.K.8
Conant, K.9
Alani, R.M.10
-
27
-
-
33750584030
-
HER2 signalling modulates the equilibrium between pro-and antiangiogenic factors via distinct pathways: Implications for HER2-targeted antibody therapy
-
Wen, X. F. et al. HER2 signalling modulates the equilibrium between pro-and antiangiogenic factors via distinct pathways: implications for HER2-targeted antibody therapy. Oncogene 25, 6986-6996 (2006).
-
(2006)
Oncogene
, vol.25
, pp. 6986-6996
-
-
Wen, X.F.1
-
28
-
-
0042972556
-
Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumor angiogenesis
-
DOI 10.1016/S1535-6108(03)00030-8
-
Watnick, R. S., Cheng, Y. N., Rangarajan, A., Ince, T. A. & Weinberg, R. A. Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumour angiogenesis. Cancer Cell 3, 219-231 (2003). (Pubitemid 37443878)
-
(2003)
Cancer Cell
, vol.3
, Issue.3
, pp. 219-231
-
-
Watnick, R.S.1
Cheng, Y.-N.2
Rangarajan, A.3
Ince, T.A.4
Weinberg, R.A.5
-
29
-
-
0033609371
-
Methylation and silencing of the Thrombospondin-1 promoter in human cancer
-
DOI 10.1038/sj.onc.1202663
-
Li, Q., Ahuja, N., Burger, P. C. & Issa, J. P. Methylation and silencing of the Thrombospondin-1 promoter in human cancer. Oncogene 18, 3284-3289 (1999). (Pubitemid 29286973)
-
(1999)
Oncogene
, vol.18
, Issue.21
, pp. 3284-3289
-
-
Li, Q.1
Ahuja, N.2
Burger, P.C.3
Issa, J.-P.J.4
-
30
-
-
37149006718
-
Hypoxia-induced increase in the production of extracellular matrix proteins in systemic sclerosis
-
DOI 10.1002/art.23074
-
Distler, J. H. et al. Hypoxia-induced increase in the production of extracellular matrix proteins in systemic sclerosis. Arthritis Rheum 56, 4203-4215 (2007). (Pubitemid 350262349)
-
(2007)
Arthritis and Rheumatism
, vol.56
, Issue.12
, pp. 4203-4215
-
-
Distler, J.H.W.1
Jungel, A.2
Pileckyte, M.3
Zwerina, J.4
Michel, B.A.5
Gay, R.E.6
Kowal-Bielecka, O.7
Matucci-Cerinic, M.8
Schett, G.9
Marti, H.H.10
Gay, S.11
Distler, O.12
-
31
-
-
0033924882
-
Opposing effects of hypoxia on expression of the angiogenic inhibitor thrombospondin 1 and the angiogenic inducer vascular endothelial growth factor
-
Laderoute, K. R. et al.Opposing effects of hypoxia on expression of the angiogenic inhibitor thrombospondin 1 and the angiogenic inducer vascular endothelial growth factor. Clin Cancer Res 6, 2941-2950 (2000). (Pubitemid 30482137)
-
(2000)
Clinical Cancer Research
, vol.6
, Issue.7
, pp. 2941-2950
-
-
Laderoute, K.R.1
Alarcon, R.M.2
Brody, M.D.3
Calaoagan, J.M.4
Chen, E.Y.5
Knapp, A.M.6
Yun, Z.7
Denko, N.C.8
Giaccia, A.J.9
-
32
-
-
50249128071
-
Hypoxia stimulates the autocrine regulation of migration of vascular smooth muscle cells via HIF-1alphadependent expression of thrombospondin-1
-
Osada-Oka, M., Ikeda, T., Akiba, S. & Sato, T. Hypoxia stimulates the autocrine regulation of migration of vascular smooth muscle cells via HIF-1alphadependent expression of thrombospondin-1. J Cell Biochem 104, 1918-1926 (2008).
-
(2008)
J Cell Biochem
, vol.104
, pp. 1918-1926
-
-
Osada-Oka, M.1
Ikeda, T.2
Akiba, S.3
Sato, T.4
-
33
-
-
77953142134
-
Hypoxic tumour cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes
-
Park, J. E. et al. Hypoxic tumour cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. Mol Cell Proteomics 9, 1085-1099 (2010).
-
(2010)
Mol Cell Proteomics
, vol.9
, pp. 1085-1099
-
-
Park, J.E.1
-
34
-
-
0032387693
-
Hypoxia increases thrombospondin-1 transcript and protein in cultured endothelial cells
-
Phelan, M. W., Forman, L. W., Perrine, S. P. & Faller, D. V. Hypoxia increases thrombospondin-1 transcript and protein in cultured endothelial cells. J Lab Clin Med 132, 519-529 (1998). (Pubitemid 28564710)
-
(1998)
Journal of Laboratory and Clinical Medicine
, vol.132
, Issue.6
, pp. 519-529
-
-
Phelan, M.W.1
Forman, L.W.2
Perrine, S.R.3
Faller, D.V.4
-
35
-
-
77952923001
-
Intermittent and sustained hypoxia induce a similar gene expression profile in the human aortic endothelial cells
-
Polotsky, V. Y. et al. Intermittent and Sustained Hypoxia Induce a Similar Gene Expression Profile in the Human Aortic Endothelial Cells. Physiol Genomics (2010).
-
(2010)
Physiol Genomics
-
-
Polotsky, V.Y.1
-
36
-
-
0034658412
-
Thrombospondin-1 is downregulated by anoxia and suppresses tumourigenicity of human glioblastoma cells
-
Tenan, M. et al. Thrombospondin-1 is downregulated by anoxia and suppresses tumourigenicity of human glioblastoma cells. J Exp Med 191, 1789-1798 (2000).
-
(2000)
J Exp Med
, vol.191
, pp. 1789-1798
-
-
Tenan, M.1
-
37
-
-
33751328746
-
Promoter region methylation and reduced expression of thrombospondin-1 after oxygen-glucose deprivation in murine cerebral endothelial cells
-
Hu, C. J. et al. Promoter region methylation and reduced expression of thrombospondin-1 after oxygen-glucose deprivation in murine cerebral endothelial cells. J Cereb Blood Flow Metab 26, 1519-1526 (2006).
-
(2006)
J Cereb Blood Flow Metab
, vol.26
, pp. 1519-1526
-
-
Hu, C.J.1
-
38
-
-
70350438226
-
The expression of thrombospondin-1 and p53 in clear cell renal cell carcinoma: Its relationship to angiogenesis, cell proliferation and cancer specific survival
-
Zubac, D. P. et al. The expression of thrombospondin-1 and p53 in clear cell renal cell carcinoma: its relationship to angiogenesis, cell proliferation and cancer specific survival. J Urol 182, 2144-2149 (2009).
-
(2009)
J Urol
, vol.182
, pp. 2144-2149
-
-
Zubac, D.P.1
-
39
-
-
36749060817
-
Transient potential receptor channel 4 controls thrombospondin-1 secretion and angiogenesis in renal cell carcinoma
-
DOI 10.1111/j.1742-4658.2007.06159.x
-
Veliceasa, D. et al. Transient potential receptor channel 4 controls thrombospondin-1 secretion and angiogenesis in renal cell carcinoma. FEBS J 274, 6365-6377 (2007). (Pubitemid 350215931)
-
(2007)
FEBS Journal
, vol.274
, Issue.24
, pp. 6365-6377
-
-
Veliceasa, D.1
Ivanovic, M.2
Hoepfner, F.T.-S.3
Thumbikat, P.4
Volpert, O.V.5
Smith, N.D.6
-
40
-
-
33749172017
-
The proangiogenic phenotype of human tumor-derived endothelial cells depends on thrombospondin-1 downregulation via phosphatidylinositol 3-kinase/Akt pathway
-
DOI 10.1007/s00109-006-0075-z
-
Bussolati, B., Assenzio, B., Deregibus, M. C. & Camussi, G. The proangiogenic phenotype of human tumour-derived endothelial cells depends on thrombospondin-1 downregulation via phosphatidylinositol 3-kinase/Akt pathway. J Mol Med 84, 852-863 (2006). (Pubitemid 44477419)
-
(2006)
Journal of Molecular Medicine
, vol.84
, Issue.10
, pp. 852-863
-
-
Bussolati, B.1
Assenzio, B.2
Deregibus, M.C.3
Camussi, G.4
-
41
-
-
33749670528
-
Signal transduction of MEK/ERK and PI3K/Akt activation by hypoxia/reoxygenation in renal epithelial cells
-
DOI 10.1016/j.ejcb.2006.06.001, PII S0171933506001166
-
Kwon, D. S. et al. Signal transduction of MEK/ERK and PI3K/Akt activation by hypoxia/reoxygenation in renal epithelial cells. Eur J Cell Biol 85, 1189-1199 (2006). (Pubitemid 44548871)
-
(2006)
European Journal of Cell Biology
, vol.85
, Issue.11
, pp. 1189-1199
-
-
Kwon, D.S.1
Kwon, C.H.2
Kim, J.H.3
Woo, J.S.4
Jung, J.S.5
Kim, Y.K.6
-
42
-
-
0035933726
-
Hypoxia induces the activation of the phosphatidylinositol 3-kinase/Akt cell survival pathway in PC12 cells: Protective role in apoptosis
-
Alvarez-Tejado, M. et al. Hypoxia induces the activation of the phosphatidylinositol 3-kinase/Akt cell survival pathway in PC12 cells: protective role in apoptosis. J Biol Chem 276, 22368-22374 (2001).
-
(2001)
J Biol Chem
, vol.276
, pp. 22368-22374
-
-
Alvarez-Tejado, M.1
-
43
-
-
0035812772
-
2, and the 3 PHDs: How animal cells signal hypoxia to the nucleus
-
DOI 10.1016/S0092-8674(01)00518-9
-
Semenza, G. L. HIF-1, O(2), and the 3 PHDs: how animal cells signal hypoxia to the nucleus. Cell 107, 1-3 (2001). (Pubitemid 32972030)
-
(2001)
Cell
, vol.107
, Issue.1
, pp. 1-3
-
-
Semenza, G.L.1
-
44
-
-
25144457125
-
Transcriptional repression of human cad gene by hypoxia inducible factor-1alpha
-
DOI 10.1093/nar/gki839
-
Chen, K. F., Lai, Y. Y., Sun, H. S. & Tsai, S. J. Transcriptional repression of human cad gene by hypoxia inducible factor-1alpha. Nucleic Acids Res 33, 5190-5198 (2005). (Pubitemid 41487827)
-
(2005)
Nucleic Acids Research
, vol.33
, Issue.16
, pp. 5190-5198
-
-
Chen, K.-F.1
Lai, Y.-Y.2
Sun, H.S.3
Tsai, S.-J.4
-
45
-
-
77950207236
-
Suppression of cyclin D1 by hypoxia-inducible factor-1 via direct mechanism inhibits the proliferation and 5-fluorouracil-induced apoptosis of A549 cells
-
Wen, W. et al. Suppression of cyclin D1 by hypoxia-inducible factor-1 via direct mechanism inhibits the proliferation and 5-fluorouracil-induced apoptosis of A549 cells. Cancer Res 70, 2010-2019 (2010).
-
(2010)
Cancer Res
, vol.70
, pp. 2010-2019
-
-
Wen, W.1
-
46
-
-
79955544394
-
Regulation of thrombospondin-1 expression through AU-rich elements in the 39UTR of the mRNA
-
McGray, A. J., Gingerich, T., Petrik, J. J. & Lamarre, J. Regulation of thrombospondin-1 expression through AU-rich elements in the 39UTR of the mRNA. Cell Mol Biol Lett 16, 55-68 (2011).
-
(2011)
Cell Mol Biol Lett
, vol.16
, pp. 55-68
-
-
McGray, A.J.1
Gingerich, T.2
Petrik, J.J.3
Lamarre, J.4
-
47
-
-
41949133416
-
Cell type-specific post-transcriptional regulation of production of the potent antiangiogenic and proatherogenic protein thrombospondin-1 by high glucose
-
Bhattacharyya, S., Marinic, T. E., Krukovets, I., Hoppe, G. & Stenina, O. I. Cell type-specific post-transcriptional regulation of production of the potent antiangiogenic and proatherogenic protein thrombospondin-1 by high glucose. J Biol Chem 283, 5699-5707 (2008).
-
(2008)
J Biol Chem
, vol.283
, pp. 5699-5707
-
-
Bhattacharyya, S.1
Marinic, T.E.2
Krukovets, I.3
Hoppe, G.4
Stenina, O.I.5
-
48
-
-
33748302836
-
Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster
-
DOI 10.1038/ng1855, PII NG1855
-
Dews, M. et al. Augmentation of tumour angiogenesis by a Myc-activated microRNA cluster. Nat Genet 38, 1060-1065 (2006). (Pubitemid 44325933)
-
(2006)
Nature Genetics
, vol.38
, Issue.9
, pp. 1060-1065
-
-
Dews, M.1
Homayouni, A.2
Yu, D.3
Murphy, D.4
Sevignani, C.5
Wentzel, E.6
Furth, E.E.7
Lee, W.M.8
Enders, G.H.9
Mendell, J.T.10
Thomas-Tikhonenko, A.11
-
49
-
-
79955534639
-
MiR-21 induced angiogenesis through AKT and ERK activation and HIF-1alpha expression
-
Liu, L. Z. et al. MiR-21 induced angiogenesis through AKT and ERK activation and HIF-1alpha expression. PLoS One 6, e19139 (2011).
-
(2011)
PLoS One
, vol.6
-
-
Liu, L.Z.1
-
50
-
-
79959906720
-
Akt2 regulates all Akt isoforms and promotes resistance to hypoxia through induction of miR-21 upon oxygen deprivation
-
Polytarchou, C. et al. Akt2 regulates all Akt isoforms and promotes resistance to hypoxia through induction of miR-21 upon oxygen deprivation. Cancer Res 71, 4720-4731 (2011).
-
(2011)
Cancer Res
, vol.71
, pp. 4720-4731
-
-
Polytarchou, C.1
-
51
-
-
7244253411
-
Inhibition of Tie-2 signaling induces endothelial cell apoptosis, decreases Akt signaling and induces endothelial cell expression of the endogenous anti-angiogenic molecule, thrombospondin-1
-
Niu, Q. et al. Inhibition of Tie-2 signalling induces endothelial cell apoptosis, decreases Akt signalling, and induces endothelial cell expression of the endogenous anti-angiogenic molecule, thrombospondin-1. Cancer Biol Ther 3, 402-405 (2004). (Pubitemid 41350872)
-
(2004)
Cancer Biology and Therapy
, vol.3
, Issue.4
, pp. 402-405
-
-
Niu, Q.1
Perruzzi, C.2
Voskas, D.3
Lawler, J.4
Dumont, D.J.5
Benjamin, L.E.6
-
52
-
-
30744432102
-
Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo
-
DOI 10.1038/nm1307, PII NM1307
-
Chen, J. et al. Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo. Nat Med. 11, 1188-1196 (2005). (Pubitemid 43093666)
-
(2005)
Nature Medicine
, vol.11
, Issue.11
, pp. 1188-1196
-
-
Chen, J.1
Somanath, P.R.2
Razorenova, O.3
Chen, W.S.4
Hay, N.5
Bornstein, P.6
Byzova, T.V.7
-
53
-
-
78649879269
-
Thrombospondin-1 inhibits VEGF receptor-2 signalling by disrupting its association with CD47
-
Kaur, S. et al. Thrombospondin-1 inhibits VEGF receptor-2 signalling by disrupting its association with CD47. J Biol Chem 285, 38923-38932 (2010).
-
(2010)
J Biol Chem
, vol.285
, pp. 38923-38932
-
-
Kaur, S.1
-
54
-
-
77953954331
-
The role of HIF prolyl hydroxylases in tumour growth
-
Jokilehto, T. & Jaakkola, P. M. The role of HIF prolyl hydroxylases in tumour growth. J Cell Mol Med 14, 758-770 (2010).
-
(2010)
J Cell Mol Med
, vol.14
, pp. 758-770
-
-
Jokilehto, T.1
Jaakkola, P.M.2
-
55
-
-
0033587146
-
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
-
DOI 10.1038/20459
-
Maxwell, P. H. et al. The tumour suppressor protein VHL targets hypoxiainducible factors for oxygen-dependent proteolysis. Nature 399, 271-275 (1999). (Pubitemid 29246458)
-
(1999)
Nature
, vol.399
, Issue.6733
, pp. 271-275
-
-
Maxwell, P.H.1
Wlesener, M.S.2
Chang, G.-W.3
Clifford, S.C.4
Vaux, E.C.5
Cockman, M.E.6
Wykoff, C.C.7
Pugh, C.W.8
Maher, E.R.9
Ratcliffe, P.J.10
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