메뉴 건너뛰기




Volumn 2, Issue , 2012, Pages

Autocrine stimulation of clear-cell renal carcinoma cell migration in hypoxia via HIF-independent suppression of thrombospondin-1

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84869155165     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep00788     Document Type: Article
Times cited : (31)

References (55)
  • 1
    • 34548680964 scopus 로고    scopus 로고
    • Plasma level and tissue expression of vascular endothelial growth factor in renal cell carcinoma: A prospective study of 50 cases
    • DOI 10.1016/j.humpath.2007.02.014, PII S0046817707001037
    • Rioux-Leclercq, N. et al. Plasma level and tissue expression of vascular endothelial growth factor in renal cell carcinoma: a prospective study of 50 cases. Hum Pathol 38, 1489-1495 (2007). (Pubitemid 47418959)
    • (2007) Human Pathology , vol.38 , Issue.10 , pp. 1489-1495
    • Rioux-Leclercq, N.1    Fergelot, P.2    Zerrouki, S.3    Leray, E.4    Jouan, F.5    Bellaud, P.6    Epstein, J.I.7    Patard, J.-J.8
  • 2
    • 34848898470 scopus 로고    scopus 로고
    • Hypoxia-inducible factors and cancer
    • Calzada, M. J. & del Peso, L. Hypoxia-inducible factors and cancer. Clin Transl Oncol 9, 278-289 (2007).
    • (2007) Clin Transl Oncol , vol.9 , pp. 278-289
    • Calzada, M.J.1    Del Peso, L.2
  • 3
    • 0035834409 scopus 로고    scopus 로고
    • A conserved family of prolyl-4-hydroxylases that modify HIF
    • DOI 10.1126/science.1066373
    • Bruick, R. K. &McKnight, S. L. A conserved family of prolyl-4-hydroxylases that modify HIF. Science 294, 1337-1340 (2001). (Pubitemid 33063099)
    • (2001) Science , vol.294 , Issue.5545 , pp. 1337-1340
    • Bruick, R.K.1    McKnight, S.L.2
  • 7
    • 67650531089 scopus 로고    scopus 로고
    • Genome-wide association of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxiainducible transcripts
    • Mole, D. R. et al. Genome-wide association of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxiainducible transcripts. J Biol Chem 284, 16767-16775 (2009).
    • (2009) J Biol Chem , vol.284 , pp. 16767-16775
    • Mole, D.R.1
  • 8
    • 77952300971 scopus 로고    scopus 로고
    • Genomewide identification of hypoxia-inducible factor binding sites and target genes by a probabilistic model integrating transcription-profiling data and in silico binding site prediction
    • Ortiz-Barahona, A., Villar, D., Pescador, N., Amigo, J. & del Peso, L. Genomewide identification of hypoxia-inducible factor binding sites and target genes by a probabilistic model integrating transcription-profiling data and in silico binding site prediction. Nucleic Acids Res 38, 2332-2345 (2010).
    • (2010) Nucleic Acids Res , vol.38 , pp. 2332-2345
    • Ortiz-Barahona, A.1    Villar, D.2    Pescador, N.3    Amigo, J.4    Del Peso, L.5
  • 9
  • 10
    • 0025147371 scopus 로고
    • A tumour suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin
    • Good, D. J. et al. A tumour suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin. Proc Natl Acad Sci USA 87, 6624-6628 (1990).
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 6624-6628
    • Good, D.J.1
  • 11
    • 0036362236 scopus 로고    scopus 로고
    • Thrombospondin-1 as an endogenous inhibitor of angiogenesis and tumor growth
    • Lawler, J. Thrombospondin-1 as an endogenous inhibitor of angiogenesis and tumour growth. J Cell Mol Med 6, 1-12 (2002). (Pubitemid 44133979)
    • (2002) Journal of Cellular and Molecular Medicine , vol.6 , Issue.1 , pp. 1-12
    • Lawler, J.1
  • 12
    • 0035049231 scopus 로고    scopus 로고
    • Thrombospondins as matricellular modulators of cell function
    • Bornstein, P. Thrombospondins as matricellular modulators of cell function. J Clin Invest 107, 929-934 (2001). (Pubitemid 32323400)
    • (2001) Journal of Clinical Investigation , vol.107 , Issue.8 , pp. 929-934
    • Bornstein, P.1
  • 14
    • 0026006134 scopus 로고
    • Antisense-mediated reduction in thrombospondin reverses the malignant phenotype of a human squamous carcinoma
    • Castle, V., Varani, J., Fligiel, S., Prochownik, E. V. & Dixit, V. Antisense-mediated reduction in thrombospondin reverses the malignant phenotype of a human squamous carcinoma. J Clin Invest 87, 1883-1888 (1991).
    • (1991) J Clin Invest , vol.87 , pp. 1883-1888
    • Castle, V.1    Varani, J.2    Fligiel, S.3    Prochownik, E.V.4    Dixit, V.5
  • 15
    • 0023270616 scopus 로고
    • Thrombospondin, a potentiator of tumor cell metastasis
    • Tuszynski, G. P., Gasic, T. B., Rothman, V. L., Knudsen, K. A. & Gasic, G. J. Thrombospondin, a potentiator of tumour cell metastasis. Cancer Res 47, 4130-4133 (1987). (Pubitemid 17108482)
    • (1987) Cancer Research , vol.47 , Issue.15 , pp. 4130-4133
    • Tuszynski, G.P.1    Gasic, T.B.2    Rothman, V.L.3
  • 16
    • 0026570066 scopus 로고
    • Biological activities of peptides and peptide analogues derived from common sequences present in thrombospondin, properdin, and malarial proteins
    • Tuszynski, G. P., Rothman, V. L., Deutch, A. H., Hamilton, B. K. & Eyal, J. Biological activities of peptides and peptide analogues derived from common sequences present in thrombospondin, properdin, and malarial proteins. J Cell Biol 116, 209-217 (1992).
    • (1992) J Cell Biol , vol.116 , pp. 209-217
    • Tuszynski, G.P.1    Rothman, V.L.2    Deutch, A.H.3    Hamilton, B.K.4    Eyal, J.5
  • 18
    • 3242772439 scopus 로고    scopus 로고
    • The thrombospondin type 1 repeat superfamily
    • DOI 10.1016/j.biocel.2003.12.011, PII S135727250300428X
    • Tucker, R. P. The thrombospondin type 1 repeat superfamily. Int J Biochem Cell Biol 36, 969-974 (2004). (Pubitemid 38501547)
    • (2004) International Journal of Biochemistry and Cell Biology , vol.36 , Issue.6 , pp. 969-974
    • Tucker, R.P.1
  • 19
    • 52049083001 scopus 로고    scopus 로고
    • Thrombospondin 1 promotes tumour macrophage recruitment and enhances tumour cell cytotoxicity of differentiated U937 cells
    • Martin-Manso, G. et al. Thrombospondin 1 promotes tumour macrophage recruitment and enhances tumour cell cytotoxicity of differentiated U937 cells. Cancer Res 68, 7090-7099 (2008).
    • (2008) Cancer Res , vol.68 , pp. 7090-7099
    • Martin-Manso, G.1
  • 20
    • 48249107523 scopus 로고    scopus 로고
    • Thrombospondin 1 and vasoactive agents indirectly alter tumour blood flow
    • Isenberg, J. S. et al. Thrombospondin 1 and vasoactive agents indirectly alter tumour blood flow. Neoplasia 10, 886-896 (2008).
    • (2008) Neoplasia , vol.10 , pp. 886-896
    • Isenberg, J.S.1
  • 21
    • 0028672529 scopus 로고
    • The p53 tumour suppressor gene inhibits angiogenesis by stimulating the production of thrombospondin
    • Dameron, K. M., Volpert, O. V., Tainsky, M. A. & Bouck, N. The p53 tumour suppressor gene inhibits angiogenesis by stimulating the production of thrombospondin. Cold Spring Harb Symp Quant Biol 59, 483-489 (1994).
    • (1994) Cold Spring Harb Symp Quant Biol , vol.59 , pp. 483-489
    • Dameron, K.M.1    Volpert, O.V.2    Tainsky, M.A.3    Bouck, N.4
  • 22
    • 0035836627 scopus 로고    scopus 로고
    • PTEN controls tumour-induced angiogenesis
    • Wen, S. et al. PTEN controls tumour-induced angiogenesis. Proc Natl Acad Sci USA 98, 4622-4627 (2001).
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 4622-4627
    • Wen, S.1
  • 23
    • 0034209874 scopus 로고    scopus 로고
    • Activation of the Myc oncoprotein leads to increased turnover of thrombospondin-1 mRNA
    • Janz, A., Sevignani, C., Kenyon, K., Ngo, C. V. & Thomas-Tikhonenko, A. Activation of the myc oncoprotein leads to increased turnover of thrombospondin-1 mRNA. Nucleic Acids Res 28, 2268-2275 (2000). (Pubitemid 30639360)
    • (2000) Nucleic Acids Research , vol.28 , Issue.11 , pp. 2268-2275
    • Janz, A.1    Sevignani, C.2    Kenyon, K.3    Ngo, C.V.4    Thomas-Tikhonenko, A.5
  • 25
    • 0028037536 scopus 로고
    • Transformation by v-src causes transient induction followed by repression of mouse thrombospondin-1
    • Slack, J. L. & Bornstein, P. Transformation by v-src causes transient induction followed by repression of mouse thrombospondin-1. Cell Growth Differ 5, 1373-1380 (1994). (Pubitemid 24381526)
    • (1994) Cell Growth and Differentiation , vol.5 , Issue.12 , pp. 1373-1380
    • Slack, J.L.1    Bornstein, P.2
  • 27
    • 33750584030 scopus 로고    scopus 로고
    • HER2 signalling modulates the equilibrium between pro-and antiangiogenic factors via distinct pathways: Implications for HER2-targeted antibody therapy
    • Wen, X. F. et al. HER2 signalling modulates the equilibrium between pro-and antiangiogenic factors via distinct pathways: implications for HER2-targeted antibody therapy. Oncogene 25, 6986-6996 (2006).
    • (2006) Oncogene , vol.25 , pp. 6986-6996
    • Wen, X.F.1
  • 28
    • 0042972556 scopus 로고    scopus 로고
    • Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumor angiogenesis
    • DOI 10.1016/S1535-6108(03)00030-8
    • Watnick, R. S., Cheng, Y. N., Rangarajan, A., Ince, T. A. & Weinberg, R. A. Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumour angiogenesis. Cancer Cell 3, 219-231 (2003). (Pubitemid 37443878)
    • (2003) Cancer Cell , vol.3 , Issue.3 , pp. 219-231
    • Watnick, R.S.1    Cheng, Y.-N.2    Rangarajan, A.3    Ince, T.A.4    Weinberg, R.A.5
  • 29
    • 0033609371 scopus 로고    scopus 로고
    • Methylation and silencing of the Thrombospondin-1 promoter in human cancer
    • DOI 10.1038/sj.onc.1202663
    • Li, Q., Ahuja, N., Burger, P. C. & Issa, J. P. Methylation and silencing of the Thrombospondin-1 promoter in human cancer. Oncogene 18, 3284-3289 (1999). (Pubitemid 29286973)
    • (1999) Oncogene , vol.18 , Issue.21 , pp. 3284-3289
    • Li, Q.1    Ahuja, N.2    Burger, P.C.3    Issa, J.-P.J.4
  • 32
    • 50249128071 scopus 로고    scopus 로고
    • Hypoxia stimulates the autocrine regulation of migration of vascular smooth muscle cells via HIF-1alphadependent expression of thrombospondin-1
    • Osada-Oka, M., Ikeda, T., Akiba, S. & Sato, T. Hypoxia stimulates the autocrine regulation of migration of vascular smooth muscle cells via HIF-1alphadependent expression of thrombospondin-1. J Cell Biochem 104, 1918-1926 (2008).
    • (2008) J Cell Biochem , vol.104 , pp. 1918-1926
    • Osada-Oka, M.1    Ikeda, T.2    Akiba, S.3    Sato, T.4
  • 33
    • 77953142134 scopus 로고    scopus 로고
    • Hypoxic tumour cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes
    • Park, J. E. et al. Hypoxic tumour cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. Mol Cell Proteomics 9, 1085-1099 (2010).
    • (2010) Mol Cell Proteomics , vol.9 , pp. 1085-1099
    • Park, J.E.1
  • 35
    • 77952923001 scopus 로고    scopus 로고
    • Intermittent and sustained hypoxia induce a similar gene expression profile in the human aortic endothelial cells
    • Polotsky, V. Y. et al. Intermittent and Sustained Hypoxia Induce a Similar Gene Expression Profile in the Human Aortic Endothelial Cells. Physiol Genomics (2010).
    • (2010) Physiol Genomics
    • Polotsky, V.Y.1
  • 36
    • 0034658412 scopus 로고    scopus 로고
    • Thrombospondin-1 is downregulated by anoxia and suppresses tumourigenicity of human glioblastoma cells
    • Tenan, M. et al. Thrombospondin-1 is downregulated by anoxia and suppresses tumourigenicity of human glioblastoma cells. J Exp Med 191, 1789-1798 (2000).
    • (2000) J Exp Med , vol.191 , pp. 1789-1798
    • Tenan, M.1
  • 37
    • 33751328746 scopus 로고    scopus 로고
    • Promoter region methylation and reduced expression of thrombospondin-1 after oxygen-glucose deprivation in murine cerebral endothelial cells
    • Hu, C. J. et al. Promoter region methylation and reduced expression of thrombospondin-1 after oxygen-glucose deprivation in murine cerebral endothelial cells. J Cereb Blood Flow Metab 26, 1519-1526 (2006).
    • (2006) J Cereb Blood Flow Metab , vol.26 , pp. 1519-1526
    • Hu, C.J.1
  • 38
    • 70350438226 scopus 로고    scopus 로고
    • The expression of thrombospondin-1 and p53 in clear cell renal cell carcinoma: Its relationship to angiogenesis, cell proliferation and cancer specific survival
    • Zubac, D. P. et al. The expression of thrombospondin-1 and p53 in clear cell renal cell carcinoma: its relationship to angiogenesis, cell proliferation and cancer specific survival. J Urol 182, 2144-2149 (2009).
    • (2009) J Urol , vol.182 , pp. 2144-2149
    • Zubac, D.P.1
  • 39
    • 36749060817 scopus 로고    scopus 로고
    • Transient potential receptor channel 4 controls thrombospondin-1 secretion and angiogenesis in renal cell carcinoma
    • DOI 10.1111/j.1742-4658.2007.06159.x
    • Veliceasa, D. et al. Transient potential receptor channel 4 controls thrombospondin-1 secretion and angiogenesis in renal cell carcinoma. FEBS J 274, 6365-6377 (2007). (Pubitemid 350215931)
    • (2007) FEBS Journal , vol.274 , Issue.24 , pp. 6365-6377
    • Veliceasa, D.1    Ivanovic, M.2    Hoepfner, F.T.-S.3    Thumbikat, P.4    Volpert, O.V.5    Smith, N.D.6
  • 40
    • 33749172017 scopus 로고    scopus 로고
    • The proangiogenic phenotype of human tumor-derived endothelial cells depends on thrombospondin-1 downregulation via phosphatidylinositol 3-kinase/Akt pathway
    • DOI 10.1007/s00109-006-0075-z
    • Bussolati, B., Assenzio, B., Deregibus, M. C. & Camussi, G. The proangiogenic phenotype of human tumour-derived endothelial cells depends on thrombospondin-1 downregulation via phosphatidylinositol 3-kinase/Akt pathway. J Mol Med 84, 852-863 (2006). (Pubitemid 44477419)
    • (2006) Journal of Molecular Medicine , vol.84 , Issue.10 , pp. 852-863
    • Bussolati, B.1    Assenzio, B.2    Deregibus, M.C.3    Camussi, G.4
  • 41
    • 33749670528 scopus 로고    scopus 로고
    • Signal transduction of MEK/ERK and PI3K/Akt activation by hypoxia/reoxygenation in renal epithelial cells
    • DOI 10.1016/j.ejcb.2006.06.001, PII S0171933506001166
    • Kwon, D. S. et al. Signal transduction of MEK/ERK and PI3K/Akt activation by hypoxia/reoxygenation in renal epithelial cells. Eur J Cell Biol 85, 1189-1199 (2006). (Pubitemid 44548871)
    • (2006) European Journal of Cell Biology , vol.85 , Issue.11 , pp. 1189-1199
    • Kwon, D.S.1    Kwon, C.H.2    Kim, J.H.3    Woo, J.S.4    Jung, J.S.5    Kim, Y.K.6
  • 42
    • 0035933726 scopus 로고    scopus 로고
    • Hypoxia induces the activation of the phosphatidylinositol 3-kinase/Akt cell survival pathway in PC12 cells: Protective role in apoptosis
    • Alvarez-Tejado, M. et al. Hypoxia induces the activation of the phosphatidylinositol 3-kinase/Akt cell survival pathway in PC12 cells: protective role in apoptosis. J Biol Chem 276, 22368-22374 (2001).
    • (2001) J Biol Chem , vol.276 , pp. 22368-22374
    • Alvarez-Tejado, M.1
  • 43
    • 0035812772 scopus 로고    scopus 로고
    • 2, and the 3 PHDs: How animal cells signal hypoxia to the nucleus
    • DOI 10.1016/S0092-8674(01)00518-9
    • Semenza, G. L. HIF-1, O(2), and the 3 PHDs: how animal cells signal hypoxia to the nucleus. Cell 107, 1-3 (2001). (Pubitemid 32972030)
    • (2001) Cell , vol.107 , Issue.1 , pp. 1-3
    • Semenza, G.L.1
  • 44
    • 25144457125 scopus 로고    scopus 로고
    • Transcriptional repression of human cad gene by hypoxia inducible factor-1alpha
    • DOI 10.1093/nar/gki839
    • Chen, K. F., Lai, Y. Y., Sun, H. S. & Tsai, S. J. Transcriptional repression of human cad gene by hypoxia inducible factor-1alpha. Nucleic Acids Res 33, 5190-5198 (2005). (Pubitemid 41487827)
    • (2005) Nucleic Acids Research , vol.33 , Issue.16 , pp. 5190-5198
    • Chen, K.-F.1    Lai, Y.-Y.2    Sun, H.S.3    Tsai, S.-J.4
  • 45
    • 77950207236 scopus 로고    scopus 로고
    • Suppression of cyclin D1 by hypoxia-inducible factor-1 via direct mechanism inhibits the proliferation and 5-fluorouracil-induced apoptosis of A549 cells
    • Wen, W. et al. Suppression of cyclin D1 by hypoxia-inducible factor-1 via direct mechanism inhibits the proliferation and 5-fluorouracil-induced apoptosis of A549 cells. Cancer Res 70, 2010-2019 (2010).
    • (2010) Cancer Res , vol.70 , pp. 2010-2019
    • Wen, W.1
  • 46
    • 79955544394 scopus 로고    scopus 로고
    • Regulation of thrombospondin-1 expression through AU-rich elements in the 39UTR of the mRNA
    • McGray, A. J., Gingerich, T., Petrik, J. J. & Lamarre, J. Regulation of thrombospondin-1 expression through AU-rich elements in the 39UTR of the mRNA. Cell Mol Biol Lett 16, 55-68 (2011).
    • (2011) Cell Mol Biol Lett , vol.16 , pp. 55-68
    • McGray, A.J.1    Gingerich, T.2    Petrik, J.J.3    Lamarre, J.4
  • 47
    • 41949133416 scopus 로고    scopus 로고
    • Cell type-specific post-transcriptional regulation of production of the potent antiangiogenic and proatherogenic protein thrombospondin-1 by high glucose
    • Bhattacharyya, S., Marinic, T. E., Krukovets, I., Hoppe, G. & Stenina, O. I. Cell type-specific post-transcriptional regulation of production of the potent antiangiogenic and proatherogenic protein thrombospondin-1 by high glucose. J Biol Chem 283, 5699-5707 (2008).
    • (2008) J Biol Chem , vol.283 , pp. 5699-5707
    • Bhattacharyya, S.1    Marinic, T.E.2    Krukovets, I.3    Hoppe, G.4    Stenina, O.I.5
  • 49
    • 79955534639 scopus 로고    scopus 로고
    • MiR-21 induced angiogenesis through AKT and ERK activation and HIF-1alpha expression
    • Liu, L. Z. et al. MiR-21 induced angiogenesis through AKT and ERK activation and HIF-1alpha expression. PLoS One 6, e19139 (2011).
    • (2011) PLoS One , vol.6
    • Liu, L.Z.1
  • 50
    • 79959906720 scopus 로고    scopus 로고
    • Akt2 regulates all Akt isoforms and promotes resistance to hypoxia through induction of miR-21 upon oxygen deprivation
    • Polytarchou, C. et al. Akt2 regulates all Akt isoforms and promotes resistance to hypoxia through induction of miR-21 upon oxygen deprivation. Cancer Res 71, 4720-4731 (2011).
    • (2011) Cancer Res , vol.71 , pp. 4720-4731
    • Polytarchou, C.1
  • 51
    • 7244253411 scopus 로고    scopus 로고
    • Inhibition of Tie-2 signaling induces endothelial cell apoptosis, decreases Akt signaling and induces endothelial cell expression of the endogenous anti-angiogenic molecule, thrombospondin-1
    • Niu, Q. et al. Inhibition of Tie-2 signalling induces endothelial cell apoptosis, decreases Akt signalling, and induces endothelial cell expression of the endogenous anti-angiogenic molecule, thrombospondin-1. Cancer Biol Ther 3, 402-405 (2004). (Pubitemid 41350872)
    • (2004) Cancer Biology and Therapy , vol.3 , Issue.4 , pp. 402-405
    • Niu, Q.1    Perruzzi, C.2    Voskas, D.3    Lawler, J.4    Dumont, D.J.5    Benjamin, L.E.6
  • 53
    • 78649879269 scopus 로고    scopus 로고
    • Thrombospondin-1 inhibits VEGF receptor-2 signalling by disrupting its association with CD47
    • Kaur, S. et al. Thrombospondin-1 inhibits VEGF receptor-2 signalling by disrupting its association with CD47. J Biol Chem 285, 38923-38932 (2010).
    • (2010) J Biol Chem , vol.285 , pp. 38923-38932
    • Kaur, S.1
  • 54
    • 77953954331 scopus 로고    scopus 로고
    • The role of HIF prolyl hydroxylases in tumour growth
    • Jokilehto, T. & Jaakkola, P. M. The role of HIF prolyl hydroxylases in tumour growth. J Cell Mol Med 14, 758-770 (2010).
    • (2010) J Cell Mol Med , vol.14 , pp. 758-770
    • Jokilehto, T.1    Jaakkola, P.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.