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Volumn 85, Issue 11, 2006, Pages 1189-1199

Signal transduction of MEK/ERK and PI3K/Akt activation by hypoxia/reoxygenation in renal epithelial cells

Author keywords

Akt; EGFR; ERK; Hypoxia reoxygenation; Opossum kidney cells; Proliferation; Reactive oxygen species; XIAP

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; 4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; ANTIOXIDANT; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RAF PROTEIN; RAS PROTEIN; REACTIVE OXYGEN METABOLITE; SURVIVIN; X LINKED INHIBITOR OF APOPTOSIS;

EID: 33749670528     PISSN: 01719335     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejcb.2006.06.001     Document Type: Article
Times cited : (80)

References (67)
  • 1
    • 0037165226 scopus 로고    scopus 로고
    • Concomitant activation of the PI3K-Akt and the Ras-ERK signaling pathways is essential for transformation by the V-SEA tyrosine kinase oncogene
    • Agazie Y., Ischenko I., and Hayman M. Concomitant activation of the PI3K-Akt and the Ras-ERK signaling pathways is essential for transformation by the V-SEA tyrosine kinase oncogene. Oncogene 21 (2002) 697-707
    • (2002) Oncogene , vol.21 , pp. 697-707
    • Agazie, Y.1    Ischenko, I.2    Hayman, M.3
  • 3
    • 28244490602 scopus 로고    scopus 로고
    • Survivin expression is regulated by coexpression of human epidermal growth factor receptor 2 and epidermal growth factor receptor via phosphatidylinositol 3-kinase/AKT signaling pathway in breast cancer cells
    • Asanuma H., Torigoe T., Kamiguchi K., Hirohashi Y., Ohmura T., Hirata K., Sato M., and Sato N. Survivin expression is regulated by coexpression of human epidermal growth factor receptor 2 and epidermal growth factor receptor via phosphatidylinositol 3-kinase/AKT signaling pathway in breast cancer cells. Cancer Res. 65 (2005) 11018-11025
    • (2005) Cancer Res. , vol.65 , pp. 11018-11025
    • Asanuma, H.1    Torigoe, T.2    Kamiguchi, K.3    Hirohashi, Y.4    Ohmura, T.5    Hirata, K.6    Sato, M.7    Sato, N.8
  • 4
    • 0020587101 scopus 로고
    • Differentiation of cell types in the mammalian kidney by immunofluorescence microscopy using antibodies to intermediate filament proteins and desmoplakins
    • Bachmann S., Kriz W., Kuhn C., and Franke W.W. Differentiation of cell types in the mammalian kidney by immunofluorescence microscopy using antibodies to intermediate filament proteins and desmoplakins. Histochemistry 77 (1983) 365-394
    • (1983) Histochemistry , vol.77 , pp. 365-394
    • Bachmann, S.1    Kriz, W.2    Kuhn, C.3    Franke, W.W.4
  • 5
    • 0030566872 scopus 로고    scopus 로고
    • The MAP kinase cascades are activated during post-ischemic liver reperfusion
    • Bendinelli P., Piccoletti R., Maroni P., and Bernelli-Zazzera A. The MAP kinase cascades are activated during post-ischemic liver reperfusion. FEBS Lett. 398 (1996) 193-197
    • (1996) FEBS Lett. , vol.398 , pp. 193-197
    • Bendinelli, P.1    Piccoletti, R.2    Maroni, P.3    Bernelli-Zazzera, A.4
  • 7
    • 2442587705 scopus 로고    scopus 로고
    • Phosphatidylinositol-3-kinase signaling is required for erythropoietin-mediated acute protection against myocardial ischemia/reperfusion injury
    • Cai Z., and Semenza G.L. Phosphatidylinositol-3-kinase signaling is required for erythropoietin-mediated acute protection against myocardial ischemia/reperfusion injury. Circulation 109 (2004) 2050-2053
    • (2004) Circulation , vol.109 , pp. 2050-2053
    • Cai, Z.1    Semenza, G.L.2
  • 8
    • 1342280338 scopus 로고    scopus 로고
    • In vivo transfection of NF-kappaB decoy oligodeoxynucleotides attenuate renal ischemia/reperfusion injury in rats
    • Cao C.C., Ding X.Q., Ou Z.L., Liu C.F., Li P., Wang L., and Zhu C.F. In vivo transfection of NF-kappaB decoy oligodeoxynucleotides attenuate renal ischemia/reperfusion injury in rats. Kidney Int. 65 (2004) 834-845
    • (2004) Kidney Int. , vol.65 , pp. 834-845
    • Cao, C.C.1    Ding, X.Q.2    Ou, Z.L.3    Liu, C.F.4    Li, P.5    Wang, L.6    Zhu, C.F.7
  • 9
    • 0035353163 scopus 로고    scopus 로고
    • Cytokine-regulated expression of survivin in myeloid leukemia
    • Carter B.Z., Milella M., Altieri D.C., and Andreeff M. Cytokine-regulated expression of survivin in myeloid leukemia. Blood 97 (2001) 2784-2790
    • (2001) Blood , vol.97 , pp. 2784-2790
    • Carter, B.Z.1    Milella, M.2    Altieri, D.C.3    Andreeff, M.4
  • 10
    • 0035866784 scopus 로고    scopus 로고
    • Hypoxia activates a platelet-derived growth factor receptor/phosphatidylinositol 3-kinase/Akt pathway that results in glycogen synthase kinase-3 inactivation
    • Chen E.Y., Mazure N.M., Cooper J.A., and Giaccia A.J. Hypoxia activates a platelet-derived growth factor receptor/phosphatidylinositol 3-kinase/Akt pathway that results in glycogen synthase kinase-3 inactivation. Cancer Res. 61 (2001) 2429-2433
    • (2001) Cancer Res. , vol.61 , pp. 2429-2433
    • Chen, E.Y.1    Mazure, N.M.2    Cooper, J.A.3    Giaccia, A.J.4
  • 12
    • 0032189381 scopus 로고    scopus 로고
    • Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation
    • Coffer P.J., Jin J., and Woodgett J.R. Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation. Biochem. J. 335 (1998) 1-13
    • (1998) Biochem. J. , vol.335 , pp. 1-13
    • Coffer, P.J.1    Jin, J.2    Woodgett, J.R.3
  • 14
    • 0030810926 scopus 로고    scopus 로고
    • X-linked IAP is a direct inhibitor of cell-death proteases
    • Deveraux Q.L., Takahashi R., Salvesen G.S., and Reed J.C. X-linked IAP is a direct inhibitor of cell-death proteases. Nature 388 (1997) 300-304
    • (1997) Nature , vol.388 , pp. 300-304
    • Deveraux, Q.L.1    Takahashi, R.2    Salvesen, G.S.3    Reed, J.C.4
  • 15
    • 0032848771 scopus 로고    scopus 로고
    • MAPK activation determines renal epithelial cell survival during oxidative injury
    • di Mari J.F., Davis R., and Safirstein R.L. MAPK activation determines renal epithelial cell survival during oxidative injury. Am. J. Physiol. 277 (1999) F195-F203
    • (1999) Am. J. Physiol. , vol.277
    • di Mari, J.F.1    Davis, R.2    Safirstein, R.L.3
  • 16
    • 0036086130 scopus 로고    scopus 로고
    • Free radicals in the physiological control of cell function
    • Droge W. Free radicals in the physiological control of cell function. Physiol. Rev. 82 (2002) 47-95
    • (2002) Physiol. Rev. , vol.82 , pp. 47-95
    • Droge, W.1
  • 17
    • 0018697595 scopus 로고
    • Recovery from postischemic acute renal failure in the rat
    • Finn W.F., and Chevalier R.L. Recovery from postischemic acute renal failure in the rat. Kidney Int. 16 (1979) 113-123
    • (1979) Kidney Int. , vol.16 , pp. 113-123
    • Finn, W.F.1    Chevalier, R.L.2
  • 18
    • 0030907987 scopus 로고    scopus 로고
    • PI3K: downstream AKTion blocks apoptosis
    • Franke T.F., Kaplan D.R., and Cantley L.C. PI3K: downstream AKTion blocks apoptosis. Cell 88 (1997) 435-437
    • (1997) Cell , vol.88 , pp. 435-437
    • Franke, T.F.1    Kaplan, D.R.2    Cantley, L.C.3
  • 19
    • 7244243972 scopus 로고    scopus 로고
    • Oxidants inhibit ERK/MAPK and prevent its ability to delay neutrophil apoptosis downstream of mitochondrial changes and at the level of XIAP
    • Gardai S.J., Whitlock B.B., Xiao Y.Q., Bratton D.B., and Henson P.M. Oxidants inhibit ERK/MAPK and prevent its ability to delay neutrophil apoptosis downstream of mitochondrial changes and at the level of XIAP. J. Biol. Chem. 279 (2004) 44695-44703
    • (2004) J. Biol. Chem. , vol.279 , pp. 44695-44703
    • Gardai, S.J.1    Whitlock, B.B.2    Xiao, Y.Q.3    Bratton, D.B.4    Henson, P.M.5
  • 20
    • 0037405098 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase coordinately activates the MEK/ERK and AKT/NFkappaB pathways to maintain osteoclast survival
    • Gingery A., Bradley E., Shaw A., and Oursler M.J. Phosphatidylinositol 3-kinase coordinately activates the MEK/ERK and AKT/NFkappaB pathways to maintain osteoclast survival. J. Cell. Biochem. 89 (2003) 165-179
    • (2003) J. Cell. Biochem. , vol.89 , pp. 165-179
    • Gingery, A.1    Bradley, E.2    Shaw, A.3    Oursler, M.J.4
  • 22
    • 0023618920 scopus 로고
    • Coexpression of keratin and vimentin in damaged and regenerating tubular epithelia of the kidney
    • Grone H.J., Weber K., Grone E., Helmchen U., and Osborn M. Coexpression of keratin and vimentin in damaged and regenerating tubular epithelia of the kidney. Am. J. Pathol. 129 (1987) 1-8
    • (1987) Am. J. Pathol. , vol.129 , pp. 1-8
    • Grone, H.J.1    Weber, K.2    Grone, E.3    Helmchen, U.4    Osborn, M.5
  • 23
    • 0035137324 scopus 로고    scopus 로고
    • Transcription factor-kappaB (NF-kappaB) and renal disease
    • Guijarro C., and Egido J. Transcription factor-kappaB (NF-kappaB) and renal disease. Kidney Int. 59 (2001) 415-424
    • (2001) Kidney Int. , vol.59 , pp. 415-424
    • Guijarro, C.1    Egido, J.2
  • 24
    • 0030049439 scopus 로고    scopus 로고
    • Activation of mitogen-activated protein kinase by H2O2: role in cell survival following oxidant injury
    • Guyton K.Z., Liu Y., Gorospe M., Xu Q., and Holbrook N.J. Activation of mitogen-activated protein kinase by H2O2: role in cell survival following oxidant injury. J. Biol. Chem. 271 (1996) 4138-4142
    • (1996) J. Biol. Chem. , vol.271 , pp. 4138-4142
    • Guyton, K.Z.1    Liu, Y.2    Gorospe, M.3    Xu, Q.4    Holbrook, N.J.5
  • 25
    • 33745043951 scopus 로고    scopus 로고
    • Regulation of late G1/S phase transition and APCCdh1 by reactive oxygen species
    • Havens C.G., Ho A., Yoshioka N., and Dowdy S.F. Regulation of late G1/S phase transition and APCCdh1 by reactive oxygen species. Mol. Cell. Biol. 26 (2006) 4701-4711
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 4701-4711
    • Havens, C.G.1    Ho, A.2    Yoshioka, N.3    Dowdy, S.F.4
  • 26
    • 0021355642 scopus 로고
    • Expression of vimentin and cytokeratin types of intermediate filament proteins in developing and adult human kidneys
    • Holthofer H., Miettinen A., Lehto V.P., Lehtonen E., and Virtanen I. Expression of vimentin and cytokeratin types of intermediate filament proteins in developing and adult human kidneys. Lab. Invest. 50 (1984) 552-559
    • (1984) Lab. Invest. , vol.50 , pp. 552-559
    • Holthofer, H.1    Miettinen, A.2    Lehto, V.P.3    Lehtonen, E.4    Virtanen, I.5
  • 27
    • 10344253840 scopus 로고    scopus 로고
    • Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death
    • Hu P., Han Z., Couvillon A.D., and Exton J.H. Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death. J. Biol. Chem. 279 (2004) 49420-49429
    • (2004) J. Biol. Chem. , vol.279 , pp. 49420-49429
    • Hu, P.1    Han, Z.2    Couvillon, A.D.3    Exton, J.H.4
  • 28
    • 0028884361 scopus 로고
    • FGF-1 in normal and regenerating kidney: expression in mononuclear, interstitial, and regenerating epithelial cells
    • Ichimura T., Maier J.A., Maciag T., Zhang G., and Stevens J.L. FGF-1 in normal and regenerating kidney: expression in mononuclear, interstitial, and regenerating epithelial cells. Am. J. Physiol. 269 (1995) F653-F662
    • (1995) Am. J. Physiol. , vol.269
    • Ichimura, T.1    Maier, J.A.2    Maciag, T.3    Zhang, G.4    Stevens, J.L.5
  • 29
    • 0034658320 scopus 로고    scopus 로고
    • Protein kinase B regulates T lymphocyte survival, nuclear factor kappaB activation, and Bcl-X(L) levels in vivo
    • Jones R.G., Parsons M., Bonnard M., Chan V.S., Yeh W.C., Woodgett J.R., and Ohashi P.S. Protein kinase B regulates T lymphocyte survival, nuclear factor kappaB activation, and Bcl-X(L) levels in vivo. J. Exp. Med. 191 (2000) 1721-1734
    • (2000) J. Exp. Med. , vol.191 , pp. 1721-1734
    • Jones, R.G.1    Parsons, M.2    Bonnard, M.3    Chan, V.S.4    Yeh, W.C.5    Woodgett, J.R.6    Ohashi, P.S.7
  • 30
    • 0033604585 scopus 로고    scopus 로고
    • The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB
    • Kandel E.S., and Hay N. The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB. Exp. Cell Res. 253 (1999) 210-229
    • (1999) Exp. Cell Res. , vol.253 , pp. 210-229
    • Kandel, E.S.1    Hay, N.2
  • 31
    • 0033983568 scopus 로고    scopus 로고
    • Parathyroid hormone stimulates extracellular signal-regulated kinase (ERK) activity through two independent signal transduction pathways: role of ERK in sodium-phosphate cotransport
    • Lederer E.D., Sohi S.S., and McLeish K.R. Parathyroid hormone stimulates extracellular signal-regulated kinase (ERK) activity through two independent signal transduction pathways: role of ERK in sodium-phosphate cotransport. J. Am. Soc. Nephrol. 11 (2000) 222-231
    • (2000) J. Am. Soc. Nephrol. , vol.11 , pp. 222-231
    • Lederer, E.D.1    Sohi, S.S.2    McLeish, K.R.3
  • 32
    • 0036238817 scopus 로고    scopus 로고
    • The Raf/MEK/ERK signal transduction cascade as a target for chemotherapeutic intervention in leukemia
    • Lee Jr. J.T., and McCubrey J.A. The Raf/MEK/ERK signal transduction cascade as a target for chemotherapeutic intervention in leukemia. Leukemia 16 (2002) 486-507
    • (2002) Leukemia , vol.16 , pp. 486-507
    • Lee Jr., J.T.1    McCubrey, J.A.2
  • 33
    • 0000601446 scopus 로고    scopus 로고
    • Life and death decisions: the role of the IAPs in modulating programmed cell death
    • Liston P., Young S.S., Mackenzie A.E., and Korneluk R.G. Life and death decisions: the role of the IAPs in modulating programmed cell death. Apoptosis 2 (1997) 423-441
    • (1997) Apoptosis , vol.2 , pp. 423-441
    • Liston, P.1    Young, S.S.2    Mackenzie, A.E.3    Korneluk, R.G.4
  • 34
    • 0034889062 scopus 로고    scopus 로고
    • Endothelial exposure to hypoxia induces Egr-1 expression involving PKCalpha-mediated Ras/Raf-1/ERK1/2 pathway
    • Lo L.W., Cheng J.J., Chiu J.J., Wung B.S., Liu Y.C., and Wang D.L. Endothelial exposure to hypoxia induces Egr-1 expression involving PKCalpha-mediated Ras/Raf-1/ERK1/2 pathway. J. Cell Physiol. 188 (2001) 304-312
    • (2001) J. Cell Physiol. , vol.188 , pp. 304-312
    • Lo, L.W.1    Cheng, J.J.2    Chiu, J.J.3    Wung, B.S.4    Liu, Y.C.5    Wang, D.L.6
  • 35
    • 0034685915 scopus 로고    scopus 로고
    • A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells
    • Madge L.A., and Pober J.S. A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells. J. Biol. Chem. 275 (2000) 15458-15465
    • (2000) J. Biol. Chem. , vol.275 , pp. 15458-15465
    • Madge, L.A.1    Pober, J.S.2
  • 37
    • 0141590207 scopus 로고    scopus 로고
    • Alpha-lipoic acid preconditioning reduces ischemia-reperfusion injury of the rat liver via the PI3-kinase/Akt pathway
    • Muller C., Dunschede F., Koch E., Vollmar A.M., and Kiemer A.K. Alpha-lipoic acid preconditioning reduces ischemia-reperfusion injury of the rat liver via the PI3-kinase/Akt pathway. Am. J. Physiol. 285 (2003) G769-G778
    • (2003) Am. J. Physiol. , vol.285
    • Muller, C.1    Dunschede, F.2    Koch, E.3    Vollmar, A.M.4    Kiemer, A.K.5
  • 38
    • 0028456132 scopus 로고
    • Proliferative activity of intrinsic cell populations in the normal human kidney
    • Nadasdy T., Laszik Z., Blick K.E., Johnson L.D., and Silva F.G. Proliferative activity of intrinsic cell populations in the normal human kidney. J. Am. Soc. Nephrol. 4 (1994) 2032-2039
    • (1994) J. Am. Soc. Nephrol. , vol.4 , pp. 2032-2039
    • Nadasdy, T.1    Laszik, Z.2    Blick, K.E.3    Johnson, L.D.4    Silva, F.G.5
  • 39
    • 0037371608 scopus 로고    scopus 로고
    • Mechanisms of renal cell repair and regeneration after acute renal failure
    • Nony P.A., and Schnellmann R.G. Mechanisms of renal cell repair and regeneration after acute renal failure. J. Pharmacol. Exp. Ther. 304 (2003) 905-912
    • (2003) J. Pharmacol. Exp. Ther. , vol.304 , pp. 905-912
    • Nony, P.A.1    Schnellmann, R.G.2
  • 41
    • 0028276071 scopus 로고
    • Hyperplasia, hypertrophy, and phenotypic alterations in the distal nephron after acute proximal tubular injury in the rat
    • Nouwen E.J., Verstrepen W.A., Buyssens N., Zhu M.Q., and De Broe M.E. Hyperplasia, hypertrophy, and phenotypic alterations in the distal nephron after acute proximal tubular injury in the rat. Lab. Invest. 70 (1994) 479-493
    • (1994) Lab. Invest. , vol.70 , pp. 479-493
    • Nouwen, E.J.1    Verstrepen, W.A.2    Buyssens, N.3    Zhu, M.Q.4    De Broe, M.E.5
  • 43
    • 0025219272 scopus 로고
    • Expression of two "immediate early" genes, Egr-1 and c-fos, in response to renal ischemia and during compensatory renal hypertrophy in mice
    • Ouellette A.J., Malt R.A., Sukhatme V.P., and Bonventre J.V. Expression of two "immediate early" genes, Egr-1 and c-fos, in response to renal ischemia and during compensatory renal hypertrophy in mice. J. Clin. Invest. 85 (1990) 766-771
    • (1990) J. Clin. Invest. , vol.85 , pp. 766-771
    • Ouellette, A.J.1    Malt, R.A.2    Sukhatme, V.P.3    Bonventre, J.V.4
  • 44
    • 0035853676 scopus 로고    scopus 로고
    • Prevention of kidney ischemia/reperfusion-induced functional injury and JNK, p38, and MAPK kinase activation by remote ischemic pretreatment
    • Park K.M., Chen A., and Bonventre J.V. Prevention of kidney ischemia/reperfusion-induced functional injury and JNK, p38, and MAPK kinase activation by remote ischemic pretreatment. J. Biol. Chem. 276 (2001) 11870-11876
    • (2001) J. Biol. Chem. , vol.276 , pp. 11870-11876
    • Park, K.M.1    Chen, A.2    Bonventre, J.V.3
  • 45
    • 0037127298 scopus 로고    scopus 로고
    • Prevention of kidney ischemia/reperfusion-induced functional injury, MAPK and MAPK kinase activation, and inflammation by remote transient ureteral obstruction
    • Park K.M., Kramers C., Vayssier-Taussat M., Chen A., and Bonventre J.V. Prevention of kidney ischemia/reperfusion-induced functional injury, MAPK and MAPK kinase activation, and inflammation by remote transient ureteral obstruction. J. Biol. Chem. 277 (2002) 2040-2049
    • (2002) J. Biol. Chem. , vol.277 , pp. 2040-2049
    • Park, K.M.1    Kramers, C.2    Vayssier-Taussat, M.3    Chen, A.4    Bonventre, J.V.5
  • 47
    • 0034992521 scopus 로고    scopus 로고
    • The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification
    • Prenzel N., Fischer O.M., Streit S., Hart S., and Ullrich A. The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification. Endocr. Relat. Cancer 8 (2001) 11-31
    • (2001) Endocr. Relat. Cancer , vol.8 , pp. 11-31
    • Prenzel, N.1    Fischer, O.M.2    Streit, S.3    Hart, S.4    Ullrich, A.5
  • 48
    • 0034142254 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase as a mediator of TNF-induced NF-kappa B activation
    • Reddy S.A., Huang J.H., and Liao W.S. Phosphatidylinositol 3-kinase as a mediator of TNF-induced NF-kappa B activation. J. Immunol. 164 (2000) 1355-1363
    • (2000) J. Immunol. , vol.164 , pp. 1355-1363
    • Reddy, S.A.1    Huang, J.H.2    Liao, W.S.3
  • 49
    • 0033517190 scopus 로고    scopus 로고
    • NF-kappaB is a target of Akt in anti-apoptotic PDGF signalling
    • Romashkova J.A., and Makarov S.S. NF-kappaB is a target of Akt in anti-apoptotic PDGF signalling. Nature 401 (1999) 86-90
    • (1999) Nature , vol.401 , pp. 86-90
    • Romashkova, J.A.1    Makarov, S.S.2
  • 51
    • 0031684690 scopus 로고    scopus 로고
    • Mechanisms of renal repair and survival following acute injury
    • Safirstein R., DiMari J., Megyesi J., and Price P. Mechanisms of renal repair and survival following acute injury. Semin. Nephrol. 18 (1998) 519-522
    • (1998) Semin. Nephrol. , vol.18 , pp. 519-522
    • Safirstein, R.1    DiMari, J.2    Megyesi, J.3    Price, P.4
  • 52
    • 0028970465 scopus 로고
    • c-Src phosphorylates epidermal growth factor receptor on tyrosine 845
    • Sato K., Sato A., Aoto M., and Fukami Y. c-Src phosphorylates epidermal growth factor receptor on tyrosine 845. Biochem. Biophys. Res. Commun. 215 (1995) 1078-1087
    • (1995) Biochem. Biophys. Res. Commun. , vol.215 , pp. 1078-1087
    • Sato, K.1    Sato, A.2    Aoto, M.3    Fukami, Y.4
  • 54
    • 0038512499 scopus 로고    scopus 로고
    • The PI3-kinase-Akt pathway promotes mesangial cell survival and inhibits apoptosis in vitro via NF-kappa B and Bad
    • Shimamura H., Terada Y., Okado T., Tanaka H., Inoshita S., and Sasaki S. The PI3-kinase-Akt pathway promotes mesangial cell survival and inhibits apoptosis in vitro via NF-kappa B and Bad. J. Am. Soc. Nephrol. 14 (2003) 1427-1434
    • (2003) J. Am. Soc. Nephrol. , vol.14 , pp. 1427-1434
    • Shimamura, H.1    Terada, Y.2    Okado, T.3    Tanaka, H.4    Inoshita, S.5    Sasaki, S.6
  • 55
    • 9644272539 scopus 로고    scopus 로고
    • Regulation of XIAP and Smac/DIABLO in the rat hippocampus following transient forebrain ischemia
    • Siegelin M.D., Kossatz L.S., Winckler J., and Rami A. Regulation of XIAP and Smac/DIABLO in the rat hippocampus following transient forebrain ischemia. Neurochem. Int. 46 (2005) 41-51
    • (2005) Neurochem. Int. , vol.46 , pp. 41-51
    • Siegelin, M.D.1    Kossatz, L.S.2    Winckler, J.3    Rami, A.4
  • 57
    • 33746425410 scopus 로고    scopus 로고
    • Alteration and clinical relevance of PTEN expression and its correlation with survivin expression in epithelial ovarian tumors
    • Sui L., Dong Y., Watanabe Y., Yamaguchi F., Sugimoto K., and Tokuda M. Alteration and clinical relevance of PTEN expression and its correlation with survivin expression in epithelial ovarian tumors. Oncol. Rep. 15 (2006) 773-778
    • (2006) Oncol. Rep. , vol.15 , pp. 773-778
    • Sui, L.1    Dong, Y.2    Watanabe, Y.3    Yamaguchi, F.4    Sugimoto, K.5    Tokuda, M.6
  • 58
    • 0026585569 scopus 로고
    • Regeneration after acute tubular necrosis
    • Toback F.G. Regeneration after acute tubular necrosis. Kidney Int. 41 (1992) 226-246
    • (1992) Kidney Int. , vol.41 , pp. 226-246
    • Toback, F.G.1
  • 59
    • 0038044666 scopus 로고    scopus 로고
    • Transgenic mice overexpressing XIAP in neurons show better outcome after transient cerebral ischemia
    • Trapp T., Korhonen L., Besselmann M., Martinez R., Mercer E.A., and Lindholm D. Transgenic mice overexpressing XIAP in neurons show better outcome after transient cerebral ischemia. Mol. Cell. Neurosci. 23 (2003) 302-313
    • (2003) Mol. Cell. Neurosci. , vol.23 , pp. 302-313
    • Trapp, T.1    Korhonen, L.2    Besselmann, M.3    Martinez, R.4    Mercer, E.A.5    Lindholm, D.6
  • 60
    • 0026717771 scopus 로고
    • Mechanism of the nephrogenic repair response. Studies on proliferation and vimentin expression after 35S-1,2-dichlorovinyl-l-cysteine nephrotoxicity in vivo and in cultured proximal tubule epithelial cells
    • Wallin A., Zhang G., Jones T.W., Jaken S., and Stevens J.L. Mechanism of the nephrogenic repair response. Studies on proliferation and vimentin expression after 35S-1,2-dichlorovinyl-l-cysteine nephrotoxicity in vivo and in cultured proximal tubule epithelial cells. Lab. Invest. 66 (1992) 474-484
    • (1992) Lab. Invest. , vol.66 , pp. 474-484
    • Wallin, A.1    Zhang, G.2    Jones, T.W.3    Jaken, S.4    Stevens, J.L.5
  • 61
    • 0034640524 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival
    • Wang X., McCullough K.D., Franke T.F., and Holbrook N.J. Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival. J. Biol. Chem. 275 (2000) 14624-14631
    • (2000) J. Biol. Chem. , vol.275 , pp. 14624-14631
    • Wang, X.1    McCullough, K.D.2    Franke, T.F.3    Holbrook, N.J.4
  • 62
    • 0028273536 scopus 로고
    • Localization of proliferating cell nuclear antigen, vimentin, c-Fos, and clusterin in the postischemic kidney: evidence for a heterogenous genetic response among nephron segments, and a large pool of mitotically active and dedifferentiated cells
    • Witzgall R., Brown D., Schwarz C., and Bonventre J.V. Localization of proliferating cell nuclear antigen, vimentin, c-Fos, and clusterin in the postischemic kidney: evidence for a heterogenous genetic response among nephron segments, and a large pool of mitotically active and dedifferentiated cells. J. Clin. Invest. 93 (1994) 2175-2188
    • (1994) J. Clin. Invest. , vol.93 , pp. 2175-2188
    • Witzgall, R.1    Brown, D.2    Schwarz, C.3    Bonventre, J.V.4
  • 63
    • 0028880006 scopus 로고
    • Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
    • Xia Z., Dickens M., Raingeaud J., Davis R.J., and Greenberg M.E. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 270 (1995) 1326-1331
    • (1995) Science , vol.270 , pp. 1326-1331
    • Xia, Z.1    Dickens, M.2    Raingeaud, J.3    Davis, R.J.4    Greenberg, M.E.5
  • 64
    • 0032134380 scopus 로고    scopus 로고
    • Hydrogen peroxide stimulates extracellular signal-regulated protein kinases in pulmonary arterial smooth muscle cells
    • Zhang J., Jin N., Liu Y., and Rhoades R.A. Hydrogen peroxide stimulates extracellular signal-regulated protein kinases in pulmonary arterial smooth muscle cells. Am. J. Respir. Cell Mol. Biol. 19 (1998) 324-332
    • (1998) Am. J. Respir. Cell Mol. Biol. , vol.19 , pp. 324-332
    • Zhang, J.1    Jin, N.2    Liu, Y.3    Rhoades, R.A.4
  • 65
    • 0034698082 scopus 로고    scopus 로고
    • Peroxynitrite targets the epidermal growth factor receptor, Raf-1, and MEK independently to activate MAPK
    • Zhang P., Wang Y.Z., Kagan E., and Bonner J.C. Peroxynitrite targets the epidermal growth factor receptor, Raf-1, and MEK independently to activate MAPK. J. Biol. Chem. 275 (2000) 22479-22486
    • (2000) J. Biol. Chem. , vol.275 , pp. 22479-22486
    • Zhang, P.1    Wang, Y.Z.2    Kagan, E.3    Bonner, J.C.4
  • 66
    • 1642441435 scopus 로고    scopus 로고
    • Neuroprotection by transforming growth factor-beta1 involves activation of nuclear factor-kappaB through phosphatidylinositol-3-OH kinase/Akt and mitogen-activated protein kinase-extracellular-signal regulated kinase1, 2 signaling pathways
    • Zhu Y., Culmsee C., Klumpp S., and Krieglstein J. Neuroprotection by transforming growth factor-beta1 involves activation of nuclear factor-kappaB through phosphatidylinositol-3-OH kinase/Akt and mitogen-activated protein kinase-extracellular-signal regulated kinase1, 2 signaling pathways. Neuroscience 123 (2004) 897-906
    • (2004) Neuroscience , vol.123 , pp. 897-906
    • Zhu, Y.1    Culmsee, C.2    Klumpp, S.3    Krieglstein, J.4
  • 67
    • 1942471141 scopus 로고    scopus 로고
    • H2O2-induced transactivation of EGF receptor requires Src and mediates ERK1/2, but not Akt, activation in renal cells
    • Zhuang S., and Schnellmann R.G. H2O2-induced transactivation of EGF receptor requires Src and mediates ERK1/2, but not Akt, activation in renal cells. Am. J. Physiol. 286 (2004) F858-F865
    • (2004) Am. J. Physiol. , vol.286
    • Zhuang, S.1    Schnellmann, R.G.2


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