Functional and molecular aspects of biotin uptake via SMVT in Human corneal epithelial (HCEC) and retinal pigment epithelial (D407) Cells

AAPS Journal

Volumn 14, Issue 4, 2012, Pages 832-842

  Vadlapudi, Aswani Dutt ^a   Vadlapatla, Ramya Krishna ^a   Pal, Dhananjay ^a   Mitra, Ashim K ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

Author keywords

Biotinylated prodrug; Human corneal epithelial cells (HCEC); Human retinal pigment epithelial cells (D407); In vitro cell culture models; SMVT

Indexed keywords

ACICLOVIR; BIOCYTIN; BIOTIN; BIOTIN DERIVATIVE; CARRIER PROTEIN; DETHIOBIOTIN; MESSENGER RNA; PANTOTHENIC ACID; RNA; SODIUM; SODIUM DEPENDENT MULTIVITAMIN TRANSPORTER; THIOCTIC ACID; TRITIUM; UNCLASSIFIED DRUG; VALERIC ACID;

ARTICLE; BIOTINYLATION; CELL IMMORTALIZATION; CELL PH; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORNEA EPITHELIUM; DRUG TRANSPORT; ENERGY; EPITHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRACELLULAR TRANSPORT; ISOTOPE LABELING; METABOLIC INHIBITION; PIGMENT EPITHELIUM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SODIUM TRANSPORT; TEMPERATURE DEPENDENCE; VITAMIN METABOLISM; VITAMIN UPTAKE;

ACYCLOVIR; BIOTIN; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIUM, CORNEAL; HUMANS; HYDROGEN-ION CONCENTRATION; PRODRUGS; RETINAL PIGMENT EPITHELIUM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SODIUM; SYMPORTERS; TEMPERATURE;

EID: 84869129469     PISSN: 15507416     EISSN: None     Source Type: Journal    
DOI: 10.1208/s12248-012-9399-5     Document Type: Article

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