Evaluation of cytotoxicity of various ophthalmic drugs, eye drop excipients and cyclodextrins in an immortalized human corneal epithelial cell line

Pharmaceutical Research

Volumn 15, Issue 8, 1998, Pages 1275-1280

  Saarinen Savolainen, Paula ^a   Järvinen, Tomi ^a   Araki Sasaki, Kaoru ^b   Watanabe, Hitoshi ^c   Urtti, Arto ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b TOYONAKA MUNICIPAL HOSPITAL   (Japan)

^c OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

Cell culture; Corneal epithelium; Cyclodextrins; Cytotoxicity; Immortalized cell line; Ocular irritation; Ophthalmic drugs

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; BENZALKONIUM CHLORIDE; BETA CYCLODEXTRIN DERIVATIVE; CYCLODEXTRIN DERIVATIVE; DEXAMETHASONE; DIPIVEFRINE; EDETATE SODIUM; EXCIPIENT; EYE DROPS; GAMMA CYCLODEXTRIN; METHYL PARABEN; PILOCARPINE; POLYVINYL ALCOHOL; TIMOLOL;

ARTICLE; CORNEA EPITHELIUM; CYTOTOXICITY TEST; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG SCREENING; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

CELL LINE, TRANSFORMED; CELL SURVIVAL; CORNEA; CYCLODEXTRINS; DRUG EVALUATION; EPITHELIAL CELLS; EXCIPIENTS; HUMANS; OPHTHALMIC SOLUTIONS;

EID: 0031687944     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011956327987     Document Type: Article

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