Systemic inflammation after aortic cross clamping is influenced by Toll-like receptor 2 preconditioning and deficiency

Journal of Surgical Research

Volumn 178, Issue 2, 2012, Pages 833-841

  Koch, Alexander ^a   Pernow, Michelle ^b   Barthuber, Carmen ^c   Mersmann, Jan ^a   Zacharowski, Kai ^a   Grotemeyer, Dirk ^d  

^a UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^b UNITED THERAPEUTICS CORPORATION   (United States)

^c UNIVERSITY HOSPITAL DÜSSELDORF   (Germany)

^d Centre Hospitalier de Kirchberg   (Luxembourg)

Author keywords

Aortic cross clamping; Cytokines; Ischemia reperfusion; Organ dysfunction; Pam3CSK4; Systemic inflammation; Toll like receptor 2

Indexed keywords

ASPARTATE AMINOTRANSFERASE; CREATININE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; LACTATE DEHYDROGENASE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR AGONIST;

ANIMAL EXPERIMENT; AORTA CLAMPING; ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; CYTOKINE RELEASE; INFLAMMATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY; UPREGULATION;

ANIMALS; AORTA, ABDOMINAL; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; INFLAMMATION; ISCHEMIC PRECONDITIONING; LIPOPEPTIDES; MALE; MICE; MICE, INBRED C57BL; TOLL-LIKE RECEPTOR 2;

EID: 84869089129     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2012.04.052     Document Type: Article

References (52)

1. J.A. Cowan Jr., J.B. Dimick, P.K. Henke, J. Rectenwald, J.C. Stanley, and G.R. Upchurch Jr. Epidemiology of aortic aneurysm repair in the United States from 1993 to 2003 Ann N Y Acad Sci 1085 2006 1
2. D. Grotemeyer, K. Strauss, B.T. Weis-Muller, A. Drabik, and W. Sandmann [Ruptured abdominal aortic aneurysm: perioperative indicators for the clinical course following conventional open surgery] Chirurgia 79 2008 745
3. G. Landry, I. Lau, T. Liem, E. Mitchell, and G. Moneta Open abdominal aortic aneurysm repair in the endovascular era: effect of clamp site on outcomes Arch Surg 144 2009 811
4. M.J. Bown, M.L. Nicholson, P.R. Bell, and R.D. Sayers Cytokines and inflammatory pathways in the pathogenesis of multiple organ failure following abdominal aortic aneurysm repair Eur J Vasc Endovasc Surg 22 2001 485
5. O.Y. Kim, A. Monsel, M. Bertrand, J.M. Cavaillon, P. Coriat, and M. Adib-Conquy Translocation of bacterial NOD2 agonist and its link with inflammation Crit Care 13 2009 R124
6. R. Pararajasingam, S.C. Weight, P.R. Bell, M.L. Nicholson, and R.D. Sayers Pulmonary nitric oxide metabolism following infrarenal aortic cross-clamp-induced ischaemia-reperfusion injury Eur J Vasc Endovasc Surg 19 2000 47
7. A. Cabie, J.C. Farkas, and C. Fitting High levels of portal TNF-alpha during abdominal aortic surgery in man Cytokine 5 1993 448
8. J.M. Rodriguez-Lopez, P. Sanchez-Conde, and F.S. Lozano Laboratory investigation: effects of propofol on the systemic inflammatory response during aortic surgery Can J Anaesth 53 2006 701
9. F.S. Lozano, J.M. Lopez-Novoa, and J.M. Rodriguez Exogenous nitric oxide modulates the systemic inflammatory response and improves kidney function after risk-situation abdominal aortic surgery J Vasc Surg 42 2005 129
10. F. Arslan, B. Keogh, P. McGuirk, and A.E. Parker TLR2 and TLR4 in ischemia reperfusion injury Mediators Inflamm 2010 2010 704202
11. A. Koch, P. Zacharowski, O. Boehm, and K. Zacharowski Innate immunity, coagulation and surgery Front Biosci 14 2009 2970
12. K.A. Zarember, and P.J. Godowski Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines J Immunol 168 2002 554
13. S.R. Bornstein, R.R. Schumann, V. Rettori, S.M. McCann, and K. Zacharowski Toll-like receptor 2 and Toll-like receptor 4 expression in human adrenals Horm Metab Res 36 2004 470
14. D.N. Cook, D.S. Pisetsky, and D.A. Schwartz Toll-like receptors in the pathogenesis of human disease Nat Immunol 5 2004 975
15. P. Matzinger Friendly and dangerous signals: is the tissue in control? Nat Immunol 8 2007 11
16. M.E. Bianchi DAMPs, PAMPs and alarmins: all we need to know about danger J Leukoc Biol 81 2007 1
17. J. Kuhlicke, J.S. Frick, J.C. Morote-Garcia, P. Rosenberger, and H.K. Eltzschig Hypoxia inducible factor (HIF)-1 coordinates induction of Toll-like receptors TLR2 and TLR6 during hypoxia PLoS One 2 2007 e1364
18. T.V. Arumugam, E. Okun, S.C. Tang, J. Thundyil, S.M. Taylor, and T.M. Woodruff Toll-like receptors in ischemia-reperfusion injury Shock 32 2009 4
19. E. Lorne, H. Dupont, and E. Abraham Toll-like receptors 2 and 4: initiators of non-septic inflammation in critical care medicine? Intensive Care Med 36 2010 1826
20. P.K. Chatterjee, K. Zacharowski, and S. Cuzzocrea Lipoteichoic acid from Staphylococcus aureus reduces renal ischemia/reperfusion injury Kidney Int 62 2002 1249
21. J. Mersmann, R. Berkels, and P. Zacharowski Preconditioning by toll-like receptor 2 agonist Pam3CSK4 reduces CXCL1-dependent leukocyte recruitment in murine myocardial ischemia/reperfusion injury Crit Care Med 38 2010 903
22. C. Lu, L. Liu, and Y. Chen TLR2 ligand induces protection against cerebral ischemia/reperfusion injury via activation of phosphoinositide 3-kinase/Akt signaling J Immunol 187 2011 1458
23. A. Iwata, V. Morgan-Stevenson, and B. Schwartz Extracellular BCL2 proteins are danger-associated molecular patterns that reduce tissue damage in murine models of ischemia-reperfusion injury PLoS One 5 2010 e9103
24. A.A. Shigeoka, T.D. Holscher, and A.J. King TLR2 is constitutively expressed within the kidney and participates in ischemic renal injury through both MyD88-dependent and -independent pathways J Immunol 178 2007 6252
25. Y. Sakata, J.W. Dong, and J.G. Vallejo Toll-like receptor 2 modulates left ventricular function following ischemia-reperfusion injury Am J Physiol Heart Circ Physiol 292 2007 H503
26. J. Mersmann, A. Koch, and N. Tran Toll-like receptor 2 signaling triggers fatal arrhythmias upon myocardial ischemia-reperfusion Crit Care Med 38 2010 1927
27. S.C. Tang, T.V. Arumugam, and X. Xu Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits Proc Natl Acad Sci U S A 104 2007 13798
28. F. Hua, J. Ma, and T. Ha Differential roles of TLR2 and TLR4 in acute focal cerebral ischemia/reperfusion injury in mice Brain Res 1262 2009 100
29. C.J. Aprahamian, R.G. Lorenz, C.M. Harmon, and R.A. Dimmit Toll-like receptor 2 is protective of ischemia-reperfusion-mediated small-bowel injury in a murine model Pediatr Crit Care Med 9 2008 105
30. X.D. Shen, B. Ke, and Y. Zhai Toll-like receptor and heme oxygenase-1 signaling in hepatic ischemia/reperfusion injury Am J Transplant 5 2005 1793
31. Y. Zhai, X.D. Shen, and R. O'Connell Cutting edge: TLR4 activation mediates liver ischemia/reperfusion inflammatory response via IFN regulatory factor 3-dependent MyD88-independent pathway J Immunol 173 2004 7115
32. A. Koch, L. Hamann, and M. Schott Genetic variation of TLR4 influences immunoendocrine stress response: an observational study in cardiac surgical patients Crit Care 15 2011 R109
33. A. Koch, K. Zacharowski, and O. Boehm Nitric oxide and pro-inflammatory cytokines correlate with pain intensity in chronic pain patients Inflamm Res 56 2007 32
34. M.M. Yassin, D.W. Harkin, A.A. Barros D'Sa, M.I. Halliday, and B.J. Rowlands Lower limb ischemia-reperfusion injury triggers a systemic inflammatory response and multiple organ dysfunction World J Surg 26 2002 115
35. K. Zacharowski, S. Frank, and M. Otto Lipoteichoic acid induces delayed protection in the rat heart: a comparison with endotoxin Arterioscler Thromb Vasc Biol 20 2000 1521
36. T. Ha, Y. Hu, and L. Liu TLR2 ligands induce cardioprotection against ischaemia/reperfusion injury through a PI3K/Akt-dependent mechanism Cardiovasc Res 87 2010 694
37. D.L. Chong, and S. Sriskandan Pro-inflammatory mechanisms in sepsis Contrib Microbiol 17 2011 86
38. M. Khajah, B. Millen, D.C. Cara, C. Waterhouse, and D.M. McCafferty Granulocyte-macrophage colony-stimulating factor (GM-CSF): a chemoattractive agent for murine leukocytes in vivo J Leukoc Biol 89 2011 945
39. S.M. Morris Jr., and T.R. Billiar New insights into the regulation of inducible nitric oxide synthesis Am J Physiol 266 1994 E829
40. C.T. Esmon Does inflammation contribute to thrombotic events? Haemostasis 30 Suppl. 2 2000 34
41. M.B. Welborn III, L.L. Moldawer, J.M. Seeger, R.M. Minter, and T.S. Huber Role of endogenous interleukin-10 in local and distant organ injury after visceral ischemia-reperfusion Shock 20 2003 35
42. R. Essner, K. Rhoades, W.H. McBride, D.L. Morton, and J.S. Economou IL-4 down-regulates IL-1 and TNF gene expression in human monocytes J Immunol 142 1989 3857
43. V.P. Marques, G.M. Goncalves, and C.Q. Feitoza Influence of TH1/TH2 switched immune response on renal ischemia-reperfusion injury Nephron Exp Nephrol 104 2006 e48
44. X.D. Shen, B. Ke, and Y. Zhai Absence of toll-like receptor 4 (TLR4) signaling in the donor organ reduces ischemia and reperfusion injury in a murine liver transplantation model Liver Transpl 13 2007 1435
45. P.J. Sullivan, K.J. Sweeney, K.M. Hirpara, C.B. Malone, W. Curtin, and M.J. Kerin Cyclical ischaemic preconditioning modulates the adaptive immune response in human limb ischaemia-reperfusion injury Br J Surg 96 2009 381
46. G. Ziegler, D. Harhausen, and C. Schepers TLR2 has a detrimental role in mouse transient focal cerebral ischemia Biochem Biophys Res Commun 359 2007 574
47. E. Lorenz, J.P. Mira, K.L. Cornish, N.C. Arbour, and D.A. Schwartz A novel polymorphism in the toll-like receptor 2 gene and its potential association with staphylococcal infection Infect Immun 68 2000 6398
48. N.W. Schroder, C. Hermann, L. Hamann, U.B. Gobel, T. Hartung, and R.R. Schumann High frequency of polymorphism Arg753Gln of the Toll-like receptor-2 gene detected by a novel allele-specific PCR J Mol Med (Berl) 81 2003 368
49. N. Kutukculer, B.S. Yeniay, G. Aksu, and A. Berdeli Arg753Gln polymorphism of the human toll-like receptor-2 gene in children with recurrent febrile infections Biochem Genet 45 2007 507
50. E. Kemna, P. Pickkers, E. Nemeth, H. van der Hoeven, and D. Swinkels Time-course analysis of hepcidin, serum iron, and plasma cytokine levels in humans injected with LPS Blood 106 2005 1864
51. P.R. Forfia, X. Zhang, and F. Ochoa Relationship between plasma NOx and cardiac and vascular dysfunction after LPS injection in anesthetized dogs Am J Physiol 274 1998 H193
52. D.M. Webel, B.N. Finck, D.H. Baker, and R.W. Johnson Time course of increased plasma cytokines, cortisol, and urea nitrogen in pigs following intraperitoneal injection of lipopolysaccharide J Anim Sci 75 1997 1514