Coxsackievirus B4 infection of human fetal thymus cells

Journal of Virology

Volumn 78, Issue 18, 2004, Pages 9854-9861

  Brilot, Fabienne ^a,b   Geenen, Vincent ^b   Hober, Didier ^c   Stoddart, Cheryl A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF LIÈGE   (Belgium)

^c University Lille   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; CD4 ANTIGEN; CD8 ANTIGEN; CHLOROQUINE; LIPOCORTIN 5; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; VIRUS RNA;

ARTICLE; CELL POPULATION; CELL SUSPENSION; CONTROLLED STUDY; CORRELATION ANALYSIS; COXSACKIE VIRUS B4; COXSACKIE VIRUS B4 E2; FETAL THYMUS ORGAN CULTURE; FETUS; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; ORGAN CULTURE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE SUBPOPULATION; THYMOCYTE; TISSUE CULTURE; UPREGULATION; VIROGENESIS; VIRUS INFECTION; VIRUS PARTICLE; VIRUS REPLICATION;

EID: 4444348507     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.78.18.9854-9861.2004     Document Type: Article

References (48)

1. Agol, V. I., G. A. Belov, K. Bienz, D. Egger, M. S. Kolesnikova, N. T. Raikhlin, L. I. Romanova, E. A. Smirnova, and E. A. Tolskaya, 1998. Two types of death of poliovirus-infected cells: caspase involvement in the apoptosis but not cytopathic effect. Virology 252:343-353.
2. Berkowitz, R. D., S. Alexander, C. Bare, V. Linquist-Stepps, M. Bogan, M. E. Moreno, L. Gibson, E. D. Wieder, J. Kosek, C. A. Stoddart, and J. M. McCune. 1998. CCR5- and CXCR4-utilizing strains of human immunodeficiency virus type 1 exhibit differential tropism and pathogenesis in vivo. J. Virol. 72:10108-10117.
3. Blue, M. L., H. Levine, J. F. Daley, K. R. Branton, and S. F. Schlossman. 1989. Expression of CD1 and class I MHC antigens by human thymocytes. J. Immunol. 142:2714-2720.
4. Bonyhadi, M. L., L. Su, J. Auten, J. M. McCune, and H. Kaneshima. 1995. Development of a human thymic organ culture model for the study of HIV pathogenesis. AIDS Res. Hum. Retrovir. 11:1073-1080.
5. Brilot, F., W. Chehadeh, C. Charlet-Renard, H. Martens, V. Geenen, and D. Hober. 2002. Persistent infection of human thymic epithelial cells by coxsackievirus B4. J. Virol. 76:5260-5265.
6. Chatterjee, N. K., J. Hou, P. Dockstader, and T. Charbonneau. 1992. Coxsackievirus B4 infection alters thymic, splenic, and peripheral lymphocyte repertoire preceding onset of hyperglycemia in mice. J. Med. Virol. 38:124-131.
7. Chehadeh, W., A. Bouzidi, G. Alm, P. Wattre, and D. Hober. 2001. Human antibodies isolated from plasma by affinity chromatography increase the coxsackievirus B4-induced synthesis of interferon-alpha by human peripheral blood mononuclear cells in vitro. J. Gen. Virol. 82:1899-1907.
8. Chehadeh, W., J. Kerr-Conte, F. Pattou, G. Alm, J. Lefebvre, P. Wattre, and D. Hober. 2000. Persistent infection of human pancreatic islets by coxsackievirus B is associated with alpha interferon synthesis in beta cells. J. Virol. 74:10153-10164.
9. Chehadeh, W., J. Weill, M. C. Vantyghem, G. Alm, J. Lefebvre, P. Wattre, and D. Hober. 2000. Increased level of interferon-alpha in blood of patients with insulin-dependent diabetes mellitus: relationship with coxsackievirus B infection. J. Infect. Dis. 181:1929-1939.
10. Dahlquist, G. 2000. Fetal virus infection a risk factor of diabetes mellitus type 1 in children. Lakartidningen 97:313-315.
11. Dahlquist, G., G. Frisk, S. A. Ivarsson, L. Svanberg, M. Forsgren, and H. Diderholm. 1995. Indications that maternal coxsackie B virus infection during pregnancy is a risk factor for childhood-onset IDDM. Diabetologia 38:1371-1373.
12. Fohlman, J., and G. Friman. 1993. Is juvenile diabetes a viral disease? Ann. Med. 25:569-574.
13. Geenen, V., and G. Kroemer. 1993. Multiple ways to cellular immune tolerance. Immunol. Today 14:573-575.
14. Ginsberg-Fellner, F., M. E. Witt, S. Yagihashi, M. J. Dobersen, F. Taub, B. Fedun, R. C. McEvoy, S. H. Roman, R. G. Davies, L. Z. Cooper, et al. 1984. Congenital rubella syndrome as a model for type 1 (insulin-dependent) diabetes mellitus: increased prevalence of islet cell surface antibodies. Diabetologia 27(Suppl.):87-89.
15. Hayashi, H., K. Tanaka, F. Jay, G. Khoury, and G. Jay. 1985. Modulation of the tumorigenicity of human adenovirus-12-transformed cells by interferon. Cell 43:263-267.
16. Hober, D., W. Chehadeh, A. Bouzidi, and P. Wattre. 2001. Antibody-dependent enhancement of coxsackievirus B4 infectivity of human peripheral blood mononuclear cells results in increased interferon-alpha synthesis. J. Infect. Dis. 184:1098-1108.
17. Horwitz, M. S., and N. Sarvetnick. 1999. Viruses, host responses, and autoimmunity. Immunol. Rev. 169:241-253.
18. Hyoty, H., M. Hiltunen, M. Knip, M. Laakkonen, P. Vahasalo, J. Karjalainen, P. Koskela, M. Roivainen, P. Leinikki, T. Hovi, et al. 1995. A prospective study of the role of coxsackic B and other enterovirus infections in the pathogenesis of IDDM. Diabetes 44:652-657.
19. Iwasaki, T., N. Monma, R. Satodate, R. Kawana, and T. Kurata. 1985. An immunofluorescent study of generalized coxsackie virus B3 infection in a newborn infant. Acta Pathol. Jpn. 35:741-748.
20. Keir, M. E., C. A. Stoddart, V. Linquist-Stepps, M. E. Moreno, and J. M. McCune. 2002. IFN-alpha secretion by type 2 predendritic cells up-regulates MHC class I in the HIV-1-infected thymus. J. Immunol. 168:325-331.
21. Keskinen, P., T. Ronni, S. Matikainen, A. Lehtonen, and I. Julkunen. 1997. Regulation of HLA class I and II expression by interferons and influenza A virus in human peripheral blood mononuclear cells. Immunology 91:421-429.
22. Kesson, A. M., Y. Cheng, and N. J. King. 2002. Regulation of immune recognition molecules by flavivirus, West Nile. Viral. Immunol. 15:273-283.
23. Klein, L., and B. Kyewski. 2000. Self-antigen presentation by thymic stromal cells: a subtle division of labor. Curr. Opin. Immunol. 12:179-186.
24. Klingel, K., S. Stephan, M. Sauter, R. Zell, B. M. McManus, B. Bultmann, and R. Kandolf. 1996. Pathogenesis of murine enterovirus myocarditis: virus dissemination and immune cell targets. J. Virol, 70:8888-8895.
25. Knip, M., and H. K. Akerblom. 1999. Environmental factors in the pathogenesis of type 1 diabetes mellitus. Exp. Clin. Endocrinol. Diabetes 107(Suppl. 3):S93-S100.
26. Koszinowski, U., and H. Ertl. 1975. Altered serological and cellular reactivity to H-2 antigens after target cell infection with vaccinia virus. Nature 257:596-597.
27. Kovalev, G., K. Duus, L. Wang, R. Lee, M. Bonyhadi, D. Ho, J. M. McCune, H. Kaneshima, and L. Su. 1999. Induction of MHC class I expression on immature thymocytes in HIV-1-infected SCID-hu Thy/Liv mice: evidence of indirect mechanisms. J. Immunol. 162:7555-7562.
28. Lansdown, A. B. 1977. Histological observations on thymic development in fetal and newborn mammals subject to intrauterine growth retardation. Biol. Neonate 31:252-259.
29. Lawlor, D. A., J. Zemmour, P. D. Ennis, and P. Parham. 1990. Evolution of class-I MHC genes and proteins: from natural selection to thymic selection. Annu. Rev. Immunol. 8:23-63.
30. Le, P. T., S. Lazorick, L. P. Whichard, Y. C. Yang, S. C. Clark, B. F. Haynes, and K. H. Singer. 1990. Human thymic epithelial cells produce IL-6, granulocyte-monocyte-CSF, and leukemia inhibitory factor. J. Immunol. 145:3310-3315.
31. Leparc, I., M. Aymard, and F. Fuchs. 1994. Acute, chronic, and persistent enterovirus and poliovirus infections: detection of viral genome y seminested PCR amplification in culture-negative samples. Mol. Cell. Probes 8:487-495.
32. Liu-Wu, Y., A. Svenningsson, S. Stemme, J. Holm, and O. Wiklund. 1997. Identification and analysis of macrophage-derived foam cells from human atherosclerotic lesions by using a "mock" FL3 channel in flow cytometry. Cytometry 29:155-164.
33. Lozovskaia, L. S., S. M. Osipov, I. V. Zubkova, and V. D. Soboleva. 1997. Study of vertical transmission of coxsackie group enteroviruses in the etiology of congenital immunodeficiencies. Vopr. Virusol. 42:175-179.
34. Matteucci, D., M. Paglianti, A. M. Giangregorio, M. R. Capobianchi, F. Dianzani, and M. Bendinelli. 1985. Group B coxsackieviruses readily establish persistent infections in human lymphoid cell lines. J. Virol. 56:651-654.
35. Oldstone, M. B. 1998. Molecular mimicry and immune-mediated diseases. FASEB J. 12:1255-1265.
36. Otonkoski, T., M. Roivainen, O. Vaarala, B. Dinesen, J. A. Leipala, T. Hovi, and M. Knip. 2000. Neonatal type I diabetes associated with maternal echo-virus 6 infection: a case report. Diabetologia 43:1235-1238.
37. Paabo, S., T. Nilsson, and P. A. Peterson. 1986. Adenoviruses of subgenera B, C, D, and E modulate cell-surface expression of major histocompatibility complex class I antigens. Proc. Natl. Acad. Sci. USA 83:9665-9669.
38. Schmidtke, M., B. Gluck, I. Merkle, P. Hofmann, A. Stelzner, and D. Gemsa. 2000. Cytokine profiles in heart, spleen, and thymus during the acute stage of experimental coxsackievirus B3-induced chronic myocarditis. J. Med. Virol. 61:518-526.
39. See, D. M., and J. G. Tilles. 1995. Pathogenesis of virus-induced diabetes in mice. J. Infect. Dis. 171:1131-1138.
40. + T regulatory cells. J. Exp. Med, 199:323-335.
41. Sinha, A. A., M. T. Lopez, and H. O. McDevitt. 1990. Autoimmune diseases: the failure of self tolerance. Science 248:1380-1388.
42. Vermes, I., C. Haanen, H. Steffens-Nakken, and C. Reutelingsperger. 1995. A novel assay for apoptosis: flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein-labeled Annexin V. J. Immunol. Methods 184:39-51.
43. Weijer, K., C. H. Uittenbogaart, A. Voordouw, F. Couwenberg, J. Seppen, B. Blom, F. A. Vyth-Dreese, and H. Spits. 2002. Intrathymic and extrathymic development of human plasmacytoid dendritic cell precursors in vivo. Blood 99:2752-2759.
44. Whitton, J. L., and R. S. Fujinami. 1999. Viruses as triggers of autoimmunity: facts and fantasies. Curr. Opin. Microbiol. 2:392-397.
45. Yewdell, J. W., and J. R. Bennink. 1999. Mechanisms of viral interference with MHC class I antigen processing and presentation. Annu. Rev. Cell. Dev. Biol. 15:579-606.
46. Yewdell, J. W., and A. B. Hill. 2002. Viral interference with antigen presentation. Nat. Immunol. 3:1019-1025.
47. Yin, H., A. K. Berg, T. Tuvemo, and G. Frisk. 2002, Enterovirus RNA is found in peripheral blood mononuclear cells in a majority of type 1 diabetic children at onset. Diabetes 51:1964-1971.
48. Yoon, J. W., M. Austin, T. Onodera, and A. L. Notkins. 1979. Isolation of a virus from the pancreas of a child with diabetic ketoacidosis. N. Engl. J. Med. 300:1173-1179.