메뉴 건너뛰기




Volumn 29, Issue 16, 2012, Pages 2555-2563

Calpastatin overexpression protects axonal transport in an in Vivo model of traumatic axonal injury

Author keywords

axonal injury; axonal transport; head trauma; traumatic brain injury; viral mediated transfection

Indexed keywords

ADENOVIRUS VECTOR; CALPAIN; CALPASTATIN;

EID: 84869048418     PISSN: 08977151     EISSN: 15579042     Source Type: Journal    
DOI: 10.1089/neu.2012.2473     Document Type: Article
Times cited : (20)

References (53)
  • 2
    • 0020369485 scopus 로고
    • Diffuse axonal injury and traumatic coma in the primate
    • DOI 10.1002/ana.410120611
    • Gennarelli, T.A., Thibault, L.E., Adams, J.H., Graham, D.I., Thompson, C.J., and Marcincin, R.P. (1982). Diffuse axonal injury and traumatic coma in the primate. Ann. Neurol. 12, 564-574 (Pubitemid 13250413)
    • (1982) Annals of Neurology , vol.12 , Issue.6 , pp. 564-574
    • Gennarelli, T.A.1    Thibault, L.E.2    Adams, J.H.3
  • 3
    • 0037370914 scopus 로고    scopus 로고
    • Axonal damage: A key predictor of outcome in human CNS diseases
    • DOI 10.1093/brain/awg061
    • Medana, I.M., and Esiri, M.M. (2003). Axonal damage: a key predictor of outcome in human CNS diseases. Brain 126, 515-530 (Pubitemid 36240854)
    • (2003) Brain , vol.126 , Issue.3 , pp. 515-530
    • Medana, I.M.1    Esiri, M.M.2
  • 4
    • 0030925162 scopus 로고    scopus 로고
    • Axonal cytoskeletal changes after non-disruptive axonal injury
    • Jafari, S.S., Maxwell, W.L., Neilson, M., and Graham, D.I. (1997). Axonal cytoskeletal changes after non-disruptive axonal injury. J. Neurocytol. 26, 207-221 (Pubitemid 27261227)
    • (1997) Journal of Neurocytology , vol.26 , Issue.4 , pp. 207-221
    • Jafari, S.S.1    Maxwell, W.L.2    Neilson, M.3    Graham, D.I.4
  • 5
    • 0030756577 scopus 로고    scopus 로고
    • Loss of axonal microtubules and neurofilaments after stretch-injury to guinea pig optic nerve fibers
    • Maxwell, W.L., and Graham, D.I. (1997). Loss of axonal microtubules and neurofilaments after stretch-injury to guinea pig optic nerve fibers. J. Neurotrauma 14, 603-614 (Pubitemid 27424264)
    • (1997) Journal of Neurotrauma , vol.14 , Issue.9 , pp. 603-614
    • Maxwell, W.L.1    Graham, D.I.2
  • 6
    • 13844284198 scopus 로고    scopus 로고
    • Update of neuropathology and neurological recovery after traumatic brain injury
    • Povlishock, J.T., and Katz, D.I. (2005). Update of neuropathology and neurological recovery after traumatic brain injury. J. Head Trauma Rehabil. 20, 76-94 (Pubitemid 40250687)
    • (2005) Journal of Head Trauma Rehabilitation , vol.20 , Issue.1 , pp. 76-94
    • Povlishock, J.T.1    Katz, D.I.2
  • 9
    • 0028788059 scopus 로고
    • Topography of axonal injury as defined by amyloid precursor protein and the sector scoring method in mild and severe closed head injury
    • Blumbergs, P.C., Scott, G., Manavis, J., Wainwright, H., Simpson, D.A., and McLean, A.J. (1995). Topography of axonal injury as defined by amyloid precursor protein and the sector scoring method in mild and severe closed head injury. J. Neurotrauma 12, 565-572
    • (1995) J. Neurotrauma , vol.12 , pp. 565-572
    • Blumbergs, P.C.1    Scott, G.2    Manavis, J.3    Wainwright, H.4    Simpson, D.A.5    McLean, A.J.6
  • 12
    • 84863078886 scopus 로고    scopus 로고
    • Short-duration treatment with the calpain inhibitor MDL-28170 does not protect axonal transport in an in vivo model of traumatic axonal injury
    • Ma, M., Li, L., Wang, X., Bull, D.L., Shofer, F.S., Meaney, D.F., and Neumar, R.W. (2012). Short-duration treatment with the calpain inhibitor MDL-28170 does not protect axonal transport in an in vivo model of traumatic axonal injury. J. Neurotrauma 29, 445-451
    • J. Neurotrauma , vol.29 , pp. 445-451
    • Ma, M.1    Li, L.2    Wang, X.3    Bull, D.L.4    Shofer, F.S.5    Meaney, D.F.6    Neumar, R.W.7
  • 13
    • 79953822054 scopus 로고    scopus 로고
    • Concussive brain trauma in the mouse results in acute cognitive deficits and sustained impairment of axonal function
    • Creed, J.A., DiLeonardi, A.M., Fox, D.P., Tessler, A.R., and Raghupathi, R. (2011). Concussive brain trauma in the mouse results in acute cognitive deficits and sustained impairment of axonal function. J. Neurotrauma 28, 547-563
    • (2011) J. Neurotrauma , vol.28 , pp. 547-563
    • Creed, J.A.1    Dileonardi, A.M.2    Fox, D.P.3    Tessler, A.R.4    Raghupathi, R.5
  • 15
    • 31344482308 scopus 로고    scopus 로고
    • All roads lead to disconnection?- Traumatic axonal injury revisited
    • Buki, A., and Povlishock, J.T. (2006). All roads lead to disconnection?- Traumatic axonal injury revisited. Acta Neurochir. (Wien) 148, 181-194
    • (2006) Acta Neurochir. (Wien) , vol.148 , pp. 181-194
    • Buki, A.1    Povlishock, J.T.2
  • 16
    • 0037350196 scopus 로고    scopus 로고
    • Preinjury administration of the calpain inhibitor MDL-28170 attenuates traumatically induced axonal injury
    • Buki, A., Farkas, O., Doczi, T., and Povlishock, J.T. (2003). Preinjury administration of the calpain inhibitor MDL-28170 attenuates traumatically induced axonal injury. J. Neurotrauma 20, 261-268 (Pubitemid 36373823)
    • (2003) Journal of Neurotrauma , vol.20 , Issue.3 , pp. 261-268
    • Buki, A.1    Farkas, O.2    Doczi, T.3    Povlishock, J.T.4
  • 17
    • 72949093813 scopus 로고    scopus 로고
    • Calpain as a therapeutic target in traumatic brain injury
    • Saatman, K.E., Creed, J., and Raghupathi, R. (2010). Calpain as a therapeutic target in traumatic brain injury. Neurotherapeutics 7, 31-42
    • (2010) Neurotherapeutics , vol.7 , pp. 31-42
    • Saatman, K.E.1    Creed, J.2    Raghupathi, R.3
  • 22
    • 34347351104 scopus 로고    scopus 로고
    • Calpain inhibitor MDL-28170 reduces the functional and structural deterioration of corpus callosum following fluid percussion injury
    • DOI 10.1089/neu.2006.0224
    • Ai, J., Liu, E., Wang, J., Chen, Y., Yu, J., and Baker, A.J. (2007). Calpain inhibitor MDL-28170 reduces the functional and structural deterioration of corpus callosum following fluid percussion injury. J. Neurotrauma 24, 960-978 (Pubitemid 47015431)
    • (2007) Journal of Neurotrauma , vol.24 , Issue.6 , pp. 960-978
    • Ai, J.1    Liu, E.2    Wang, J.3    Chen, Y.4    Yu, J.5    Baker, A.J.6
  • 24
    • 17644393902 scopus 로고    scopus 로고
    • Distinct mechanistic roles of calpain and caspase activation in neurodegeneration as revealed in mice overexpressing their specific inhibitors
    • DOI 10.1074/jbc.M500939200
    • Higuchi, M., Tomioka, M., Takano, J., Shirotani, K., Iwata, N., Masumoto, H., Maki, M., Itohara, S., and Saido, T.C. (2005). Distinct mechanistic roles of calpain and caspase activation in neurodegeneration as revealed in mice overexpressing their specific inhibitors. J. Biol. Chem. 280, 15229-15237 (Pubitemid 40562879)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.15 , pp. 15229-15237
    • Higuchi, M.1    Tomioka, M.2    Takano, J.3    Shirotani, K.4    Iwata, N.5    Masumoto, H.6    Maki, M.7    Itohara, S.8    Saido, T.C.9
  • 26
    • 18144407551 scopus 로고    scopus 로고
    • Calpain mediates excitotoxic DNA fragmentation via mitochondrial pathways in adult brains: Evidence from calpastatin mutant mice
    • DOI 10.1074/jbc.M414552200
    • Takano, J., Tomioka, M., Tsubuki, S., Higuchi, M., Iwata, N., Itohara, S., Maki, M., and Saido, T.C. (2005). Calpain mediates excitotoxic DNA fragmentation via mitochondrial pathways in adult brains: evidence from calpastatin mutant mice. J. Biol. Chem. 280, 16175-16184 (Pubitemid 40616744)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.16 , pp. 16175-16184
    • Takano, J.1    Tomioka, M.2    Tsubuki, S.3    Higuchi, M.4    Iwata, N.5    Itohara, S.6    Maki, M.7    Saido, T.C.8
  • 27
    • 34548431366 scopus 로고    scopus 로고
    • Critical role of calpain I in mitochondrial release of apoptosis-inducing factor in ischemic neuronal injury
    • DOI 10.1523/JNEUROSCI.2826-07.2007
    • Cao, G., Xing, J., Xiao, X., Liou, A.K.F., Gao, Y., Yin, X.-M., Clark, R.S.B., Graham, S.H., and Chen, J. (2007). Critical role of calpain I in mitochondrial release of apoptosis-inducing factor in ischemic neuronal injury. J. Neurosci. 27, 9278-9293 (Pubitemid 47358221)
    • (2007) Journal of Neuroscience , vol.27 , Issue.35 , pp. 9278-9293
    • Cao, G.1    Xing, J.2    Xiao, X.3    Liou, A.K.F.4    Gao, Y.5    Yin, X.-M.6    Clark, R.S.B.7    Graham, S.H.8    Chen, J.9
  • 29
    • 0037285301 scopus 로고    scopus 로고
    • Intraocular elevation of cyclic AMP potentiates ciliary neurotrophic factor-induced regeneration of adult rat retinal ganglion cell axons
    • DOI 10.1016/S1044-7431(02)00037-4
    • Cui, Q., Yip, H.K., Zhao, R.C.H., So, K.-F., and Harvey, A.R. (2003). Intraocular elevation of cyclic AMP potentiates ciliary neurotrophic factor-induced regeneration of adult rat retinal ganglion cell axons. Mol. Cell. Neurosci. 22, 49-61 (Pubitemid 36269115)
    • (2003) Molecular and Cellular Neuroscience , vol.22 , Issue.1 , pp. 49-61
    • Cui, Q.1    Yip, H.K.2    Zhao, R.C.H.3    So, K.-F.4    Harvey, A.R.5
  • 30
    • 57449106456 scopus 로고    scopus 로고
    • Immediate short-duration hypothermia provides long-term protection in an in vivo model of traumatic axonal injury
    • Ma, M., Matthews, B.T., Lampe, J.W., Meaney, D.F., Shofer, F.S., and Neumar, R.W. (2009). Immediate short-duration hypothermia provides long-term protection in an in vivo model of traumatic axonal injury. Exp. Neurol. 215, 119-127
    • (2009) Exp. Neurol , vol.215 , pp. 119-127
    • Ma, M.1    Matthews, B.T.2    Lampe, J.W.3    Meaney, D.F.4    Shofer, F.S.5    Neumar, R.W.6
  • 32
    • 0033103225 scopus 로고    scopus 로고
    • Axon/dendrite targeting of metabotropic glutamate receptors by their cytoplasmic carboxy-terminal domains
    • Stowell, J.N., and Craig, A.M. (1999). Axon/dendrite targeting of metabotropic glutamate receptors by their cytoplasmic carboxy-terminal domains. Neuron 22, 525-536 (Pubitemid 29159851)
    • (1999) Neuron , vol.22 , Issue.3 , pp. 525-536
    • Stowell, J.N.1    Craig, A.M.2
  • 33
    • 16344394331 scopus 로고    scopus 로고
    • Re-establishing the regenerative potential of central nervous system axons in postnatal mice
    • DOI 10.1242/jcs.01658
    • Cho, K.-S., Yang, L., Lu, B., Ma, H.F., Huang, X., Pekny, M., and Chen, D.F. (2005). Re-establishing the regenerative potential of central nervous system axons in postnatal mice. J. Cell Sci. 118, 863-872 (Pubitemid 40484879)
    • (2005) Journal of Cell Science , vol.118 , Issue.5 , pp. 863-872
    • Cho, K.-S.1    Yang, L.2    Lu, B.3    Ma, H.F.4    Huang, X.5    Pekny, M.6    Chen, D.F.7
  • 34
    • 0002105398 scopus 로고
    • The Axon: Structure, Function, and Pathophysiology. S.G. Waxman, J.D. Kocsis, and P.K. Stys (eds Oxford University Press: New York
    • Hirano, A., and Lena, J.F. (1995). Morphology of central nervous system axons, in: The Axon: Structure, Function, and Pathophysiology. S.G. Waxman, J.D. Kocsis, and P.K. Stys (eds). Oxford University Press: New York, pps. 49-67
    • (1995) Morphology of Central Nervous System Axons , pp. 49-67
    • Hirano, A.1    Lena, J.F.2
  • 35
    • 9944226710 scopus 로고    scopus 로고
    • Gene therapy for optic nerve disease
    • DOI 10.1038/sj.eye.6701579
    • Martin, K.R.G., and Quigley, H.A. (2004). Gene therapy for optic nerve disease. Eye (Lond.) 18, 1049-1055 (Pubitemid 39591786)
    • (2004) Eye , vol.18 , Issue.11 , pp. 1049-1055
    • Martin, K.R.G.1    Quigley, H.A.2
  • 36
    • 0016587145 scopus 로고
    • Biochemical studies on the in vitro assembly and disassembly of microtubules
    • Gaskin, F., Cantor, C.R., and Shelanski, M.L. (1975). Biochemical studies on the in vitro assembly and disassembly of microtubules. Ann. NY Acad. Sci. 253, 133-146
    • (1975) Ann. NY Acad. Sci , vol.253 , pp. 133-146
    • Gaskin, F.1    Cantor, C.R.2    Shelanski, M.L.3
  • 38
    • 0021013017 scopus 로고
    • ++-calmodulin causes a localized depolymerization of microtubules
    • Keith, C., DiPaola, M., Maxfield, F.R., and Shelanski, M.L. (1983). Microinjection of Ca+ +-calmodulin causes a localized depolymerization of microtubules. J. Cell Biol. 97, 1918-1924 (Pubitemid 14208916)
    • (1983) Journal of Cell Biology , vol.97 , Issue.6 , pp. 1918-1924
    • Keith, C.1    DiPaola, M.2    Maxfield, F.R.3    Shelanski, M.L.4
  • 39
    • 0030752893 scopus 로고    scopus 로고
    • A mechanistic analysis of nondisruptive axonal injury: A review
    • Maxwell, W.L., Povlishock, J.T., and Graham, D.L. (1997). A mechanistic analysis of nondisruptive axonal injury: a review. J. Neurotrauma 14, 419-440 (Pubitemid 27338081)
    • (1997) Journal of Neurotrauma , vol.14 , Issue.7 , pp. 419-440
    • Maxwell, W.L.1    Povlishock, J.T.2    Graham, D.L.3
  • 40
    • 0034655408 scopus 로고    scopus 로고
    • Cytochrome c release and caspase activation in traumatic axonal injury
    • Buki, A., Okonkwo, D.O., Wang, K.K.W., and Povlishock, J.T. (2000). Cytochrome c release and caspase activation in traumatic axonal injury. J. Neurosci. 20, 2825-2834 (Pubitemid 30220307)
    • (2000) Journal of Neuroscience , vol.20 , Issue.8 , pp. 2825-2834
    • Buki, A.1    Okonkwo, D.O.2    Wang, K.K.W.3    Povlishock, J.T.4
  • 42
    • 0033730926 scopus 로고    scopus 로고
    • Axonal damage in traumatic brain injury
    • Smith, D.H., and Meaney, D.F. (2000). Axonal damage in traumatic brain injury. Neuroscientist 6, 483-495
    • (2000) Neuroscientist , vol.6 , pp. 483-495
    • Smith, D.H.1    Meaney, D.F.2
  • 43
    • 0029736959 scopus 로고    scopus 로고
    • Histopathological changes at central nodes of Ranvier after stretch- injury
    • DOI 10.1002/(SICI)1097-0029(19960815)34:6 <522::AID-JEMT4>3.0.CO;2- L
    • Maxwell, W.L. (1996). Histopathological changes at central nodes of Ranvier after stretch-injury. Microsc. Res. Tech. 34, 522-535 (Pubitemid 26268677)
    • (1996) Microscopy Research and Technique , vol.34 , Issue.6 , pp. 522-535
    • Maxwell, W.L.1
  • 44
    • 0032857975 scopus 로고    scopus 로고
    • Calpain activation and cytoskeletal protein breakdown in the corpus callosum of head-injured patients
    • McCracken, E., Hunter, A.J., Patel, S., Graham, D.I., and Dewar, D. (1999). Calpain activation and cytoskeletal protein breakdown in the corpus callosum of head-injured patients. J. Neurotrauma 16, 749-761 (Pubitemid 29466369)
    • (1999) Journal of Neurotrauma , vol.16 , Issue.9 , pp. 749-761
    • McCracken, E.1    Hunter, A.J.2    Patel, S.3    Graham, D.I.4    Dewar, D.5
  • 45
    • 0023931244 scopus 로고
    • Proteolysis of tubulin and microtubule-associated proteins 1 and 2 by calpain I and II. Difference in sensitivity of assembled and disassembled microtubules
    • DOI 10.1016/0143-4160(88)90036-X
    • Billger, M., Wallin, M., and Karlsson, J.-O. (1988). Proteolysis of tubulin and microtubule-associated proteins 1 and 2 by calpain I and II. Difference in sensitivity of assembled and disassembled microtubules. Cell Calcium 9, 33-44 (Pubitemid 18070339)
    • (1988) Cell Calcium , vol.9 , Issue.1 , pp. 33-44
    • Billger, M.1    Wallin, M.2    Karlsson, J.-O.3
  • 47
    • 0024020782 scopus 로고
    • Excitatory amino acids activate calpain i and induce structural protein breakdown in vivo
    • Siman, R., and Noszek, J.C. (1988). Excitatory amino acids activate calpain I and induce structural protein breakdown in vivo. Neuron 1, 279-287
    • (1988) Neuron , vol.1 , pp. 279-287
    • Siman, R.1    Noszek, J.C.2
  • 48
    • 26844433579 scopus 로고    scopus 로고
    • Microtubules and maps
    • DOI 10.1016/S0065-3233(04)71007-4, PII S0065323304710074
    • Amos, L.A., and Schlieper, D. (2005). Microtubules and MAPs. Adv. Protein Chem. 71, 257-298 (Pubitemid 41446931)
    • (2005) Advances in Protein Chemistry , vol.71 , pp. 257-298
    • Amos, L.A.1    Schlieper, D.2
  • 49
    • 0031041436 scopus 로고    scopus 로고
    • How calcium causes microtubule depolymerization
    • DOI 10.1002/(SICI)1097-0169(1997)36:2 <125::AID-CM3>3.0.CO;2-8
    • O'Brien, E.T., Salmon, E.D., and Erickson, H.P. (1997). How calcium causes microtubule depolymerization. Cell Motil. Cytoskeleton 36, 125-135 (Pubitemid 27063205)
    • (1997) Cell Motility and the Cytoskeleton , vol.36 , Issue.2 , pp. 125-135
    • O'Brien, E.T.1    Salmon, E.D.2    Erickson, H.P.3
  • 50
    • 2442662940 scopus 로고    scopus 로고
    • Traumatic axonal injury induces proteolytic cleavage of the voltage-gated sodium channels modulated by tetrodotoxin and protease inhibitors
    • DOI 10.1523/JNEUROSCI.0515-03.2004
    • Iwata, A., Stys, P.K., Wolf, J.A., Chen, X.-H., Taylor, A.G., Meaney, D.F., and Smith, D.H. (2004). Traumatic axonal injury induces proteolytic cleavage of the voltage-gated sodium channels modulated by tetrodotoxin and protease inhibitors. J. Neurosci. 24, 4605-4613 (Pubitemid 38656616)
    • (2004) Journal of Neuroscience , vol.24 , Issue.19 , pp. 4605-4613
    • Iwata, A.1    Stys, P.K.2    Wolf, J.A.3    Chen, X.-H.4    Taylor, A.G.5    Meaney, D.F.6    Smith, D.H.7
  • 51
    • 75949102425 scopus 로고    scopus 로고
    • Initial calcium release from intracellular stores followed by calcium dysregulation is linked to secondary axotomy following transient axonal stretch injury
    • Staal, J.A., Dickson, T.C., Gasperini, R., Liu, Y., Foa, L., and Vickers, J.C. (2010). Initial calcium release from intracellular stores followed by calcium dysregulation is linked to secondary axotomy following transient axonal stretch injury. J. Neurochem. 112, 1147-1155
    • (2010) J. Neurochem , vol.112 , pp. 1147-1155
    • Staal, J.A.1    Dickson, T.C.2    Gasperini, R.3    Liu, Y.4    Foa, L.5    Vickers, J.C.6
  • 52
    • 0035690458 scopus 로고    scopus 로고
    • Intra-axonal neurofilament compaction does not evoke local axonal swelling in all traumatically injured axons
    • DOI 10.1006/exnr.2001.7818
    • Stone, J.R., Singleton, R.H., and Povlishock, J.T. (2001). Intra-axonal neurofilament compaction does not evoke local axonal swelling in all traumatically injured axons. Exp. Neurol. 172, 320-331 (Pubitemid 34075081)
    • (2001) Experimental Neurology , vol.172 , Issue.2 , pp. 320-331
    • Stone, J.R.1    Singleton, R.H.2    Povlishock, J.T.3
  • 53
    • 0024587013 scopus 로고
    • Protein changes during anterograde-to-retrograde conversion of axonally transported vesicles
    • DOI 10.1016/0006-8993(89)91559-X
    • Sahenk, Z., and Lasek, R.J. (1988). Inhibition of proteolysis blocks anterograde-retrograde conversion of axonally transported vesicles. Brain Res. 460, 199-203. (Pubitemid 19006387)
    • (1989) Brain Research , vol.476 , Issue.1 , pp. 199-203
    • Martz, D.1    Garner, J.2    Lasek, R.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.