Structure-activity relationship (SAR) analysis of a family of steroids acutely controlling steroidogenesis

Steroids

Volumn 77, Issue 13, 2012, Pages 1327-1334

  Midzak, Andrew ^a   Rammouz, Georges ^a,b   Papadopoulos, Vassilios ^a  

^a RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^b American University of Technology   (Lebanon)

Author keywords

Androstenetriol; Cholesterol; CRAC; Steroidogenesis; TSPO

Indexed keywords

3 ANDROSTEN 17,19 DIOL 3 ONE; 4 ANDROSTEN 3,17 DIONE 19 ALDEHYDE; 4 ANDROSTEN 3BETA,17BETA DIOL 11 ONE; 5 ANDROSTEN 3BETA,11BETA,17BETA TRIOL; 5 ANDROSTEN 3BETA,16ALPHA,17ALPHA TRIOL; 5 ANDROSTEN 3BETA,16ALPHA,17BETA TRIOL; 5 ANDROSTEN 3BETA,16BETA,17ALPHA TRIOL; 5 ANDROSTEN 3BETA,16BETA,17BETA TRIOL; 5 ANDROSTEN 3BETA,17,19 TRIOL; 5 ANDROSTEN 3BETA,17BETA DIOL 11 ONE; 5 ANDROSTEN 3BETA,19 DIOL 17 ONE; 5 ANDROSTEN 3BETA,4ALPHA,17BETA TRIOL; 5 ANDROSTEN 3BETA,7ALPHA,17BETA TRIOL; 5 ANDROSTEN 3BETA,7BETA DIOL 17 ONE; 5 ANDROSTEN 3BETA,7BETA,17BETA TRIOL; ANDROSTENETRIOL DERIVATIVE; CARBON; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CYCLIC AMP; MITOCHONDRIAL PROTEIN; PROTEIN CHOLESTEROL RECOGNITION INTERACTION AMINO ACID CONSENSUS; STEROID; TRANSLOCATOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHOLESTEROL TRANSPORT; DRUG STRUCTURE; HYDROXYLATION; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; OXYGENATION; PROTEIN MOTIF; STEROIDOGENESIS; STRUCTURE ACTIVITY RELATION;

ANIMALS; CELL LINE, TUMOR; CELL SURVIVAL; HYDROXYLATION; MICE; MITOCHONDRIA; OXYGEN; RECEPTORS, GABA; STEROIDS; STRUCTURE-ACTIVITY RELATIONSHIP;

VERTEBRATA;

EID: 84869030867     PISSN: 0039128X     EISSN: 18785867     Source Type: Journal    
DOI: 10.1016/j.steroids.2012.08.019     Document Type: Article

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