A review of mechanistic studies on aromatase (CYP19) and 17α-hydroxylase-17,20-lyase (CYP17)

Journal of Steroid Biochemistry and Molecular Biology

Volumn 125, Issue 1-2, 2011, Pages 2-12

  Akhtar, Muhammad ^a,b   Wright, J Neville ^b   Lee Robichaud, Peter ^c  

^a UNIVERSITY OF THE PUNJAB   (Pakistan)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^c ROYAL HAMPSHIRE COUNTY HOSPITAL   (United Kingdom)

Author keywords

Androgen biosynthesis; Aromatase; CYP17; Cytochrome b5; Iron oxygen species; P 450 17alpha CYP19; P 450c17; P450c17; Steroid biosynthesis

Indexed keywords

17 HYDROXYPREGNENOLONE; ABIRATERONE; ANASTROZOLE; AROMATASE; CYTOCHROME B5; CYTOCHROME P450C17; EXEMESTANE; HYDROXYPROGESTERONE; IRON COMPLEX; LETROZOLE; LYASE; OXYGENASE;

CONFORMATIONAL TRANSITION; CORTICOSTEROID METABOLISM; ENZYME ACTIVITY; ENZYME MECHANISM; ESTROGEN SYNTHESIS; HUMAN; PROTEIN CLEAVAGE; REVIEW; STEROID HYDROXYLATION; STRUCTURE ACTIVITY RELATION;

AROMATASE; CATALYSIS; ENZYME INHIBITORS; FERRIC COMPOUNDS; FERROUS COMPOUNDS; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; STEROID 17-ALPHA-HYDROXYLASE;

EID: 79957731214     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2010.11.003     Document Type: Review

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