The anti-tumor effects of androstene steroids exhibit a strict structure-activity relationship dependent upon the orientation of the hydroxyl group on carbon-17

Chemical Biology and Drug Design

Volumn 74, Issue 6, 2009, Pages 625-629

  Graf, Martin R ^a   Jia, Wentao ^a   Lewbart, Marvin L ^b   Loria, Roger M ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY MEDICAL CENTER   (United States)

^b Custom Steroid Synthesis   (United States)

Author keywords

Androstene steroids; Apoptosis; Autophagy; Glioblastoma; Lymphoma; Structure activity

Indexed keywords

ANDROSTERONE; PRASTERONE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG STRUCTURE; GLIOBLASTOMA; HUMAN; HUMAN CELL; LYMPHOMA CELL; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANDROSTENES; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; STRUCTURE-ACTIVITY RELATIONSHIP; U937 CELLS;

EID: 70350555435     PISSN: 17470277     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2009.00900.x     Document Type: Article

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