The role of TLR and chemokine in wear particle-induced aseptic loosening

Journal of Biomedicine and Biotechnology

Volumn 2012, Issue , 2012, Pages

  Gu, Qiaoli ^a   Shi, Qin ^a   Yang, Huilin ^a  

^a THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR; INTERLEUKIN 8; MACROPHAGE MIGRATION INHIBITION FACTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR;

CELL DIFFERENTIATION; CELL INTERACTION; CELL MIGRATION; HUMAN; INFLAMMATORY CELL; MACROPHAGE; MONOCYTE; OSTEOCLAST; PROSTHESIS LOOSENING; REVIEW; ANIMAL; CELL MOTION; METABOLISM; PROSTHESES AND ORTHOSES; PROSTHESIS FAILURE; SIGNAL TRANSDUCTION;

ANIMALS; CELL MOVEMENT; CHEMOKINES; HUMANS; PROSTHESES AND IMPLANTS; PROSTHESIS FAILURE; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS;

EID: 84868686900     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/2012/596870     Document Type: Review

References (83)

1. Farber A., Chin R., Song Y., Huie P., Goodman S., Chronic antigen-specific immune-system activation may potentially be involved in the loosening of cemented acetabular components. Journal of Biomedical Materials Research 2001 55 3 433 441 2-s2.0-0035811280 10.1002/1097-4636(20010605)55:3433: :AID-JBM1033>3.0.CO;2-N (Pubitemid 32240181)
2. Koulouvaris P., Ly K., Ivashkiv L. B., Bostrom M. P., Nestor B. J., Sculco T. P., Purdue P. E., Expression profiling reveals alternative macrophage activation and impaired osteogenesis in periprosthetic osteolysis. Journal of Orthopaedic Research 2008 26 1 106 116 2-s2.0-38049075337 10.1002/jor.20486
3. Chiu R., Ting M., Smith R. L., Goodman S. B., Ultrahigh molecular weight polyethylene wear debris inhibits osteoprogenitor proliferation and differentiation in vitro. Journal of Biomedical Materials Research Part A 2009 89 1 242 247 2-s2.0-62249178589 10.1002/jbm.a.32001
4. Kurtz S., Ong K., Lau E., Mowat F., Halpern M., Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030. Journal of Bone and Joint Surgery Series A 2007 89 4 780 785 2-s2.0-34147150632 10.2106/JBJS.F.00222 (Pubitemid 46564282)
5. Herberts P., Malchau H., Long-term registration has improved the quality of hip replacement: a review of the Swedish THR Register comparing 160,000 cases. Acta Orthopaedica Scandinavica 2000 71 2 111 121 2-s2.0-0033861254 (Pubitemid 30611734)
6. Robertsson O., Knutson K., Lewold S., Lidgren L., The Swedish Knee Arthroplasty Register 19751997: an update with special emphasis on 41,223 knees operated on in 19881997. Acta Orthopaedica Scandinavica 2001 72 5 503 513 2-s2.0-0034762231 10.1080/000164701753532853 (Pubitemid 33043591)
7. Ingham E., Fisher J., The role of macrophages in osteolysis of total joint replacement. Biomaterials 2005 26 11 1271 1286 2-s2.0-4744355541 10.1016/j.biomaterials.2004.04.035 (Pubitemid 39314501)
8. Goodman S., Aspenberg P., Song Y., Knoblich G., Huie P., Regula D., Lidgren L., Tissue ingrowth and differentiation in the bone-harvest chamber in the presence of cobalt-chromium-alloy and high-density-polyethylene particles. Journal of Bone and Joint Surgery Series A 1995 77 7 1025 1035 2-s2.0-0029020276
9. Maloney W. J., Smith R. L., Periprosthetic osteolysis in total hip arthroplasty: the role of particulate wear debris. Instructional Course Lectures 1996 45 171 182 2-s2.0-0029717670
10. Rao A. J., Gibon E., Ma T., Yao Z., Smith R. L., Goodman S. B., Revision joint replacement, wear particles, and macrophage polarization. Acta Biomaterialia 2012 8 7 2815 2823 2-s2.0-84861582394 10.1016/j.actbio.2012.03.042
11. Witt J. D., Swann M., Metal wear and tissue response in failed titanium alloy total hip replacements. Journal of Bone and Joint Surgery Series B 1991 73 4 559 563 2-s2.0-0025874154
12. Wooley P. H., Schwarz E. M., Aseptic loosening. Gene Therapy 2004 11 4 402 407 2-s2.0-1342327556 10.1038/sj.gt.3302202 (Pubitemid 38263090)
13. Purdue P. E., Alternative macrophage activation in periprosthetic osteolysis. Autoimmunity 2008 41 3 212 217 2-s2.0-41449089672 10.1080/08916930701694626 (Pubitemid 351454991)
14. Miyanishi K., Trindade M. C. D., Ma T., Goodman S. B., Schurman D. J., Smith R. L., Periprosthetic osteolysis: induction of vascular endothelial growth factor from human monocyte/macrophages by orthopaedic biomaterial particles. Journal of Bone and Mineral Research 2003 18 9 1573 1583 2-s2.0-0042978781 10.1359/jbmr.2003.18.9.1573 (Pubitemid 37022915)
15. Purdue P. E., Koulouvaris P., Nestor B. J., Sculco T. P., The central role of wear debris in periprosthetic osteolysis. HSS Journal 2006 2 2 102 113 2-s2.0-33748291470 10.1007/s11420-006-9003-6 (Pubitemid 44328104)
16. Horowitz S. M., Gonzales J. B., Inflammatory response to implant particulates in a macrophage/osteoblast coculture model. Calcified Tissue International 1996 59 5 392 396 2-s2.0-0029864496 10.1007/s002239900145 (Pubitemid 26367088)
17. St Pierre C. A., Chan M., Iwakura Y., Ayers D. C., Kurt-Jones E. A., Finberg R. W., Periprosthetic osteolysis: characterizing the innate immune response to titanium wear-particles. Journal of Orthopaedic Research 2010 28 11 1418 1424 2-s2.0-77957957053 10.1002/jor.21149
18. Beck R. T., Illingworth K. D., Saleh K. J., Review of periprosthetic osteolysis in total joint arthroplasty: an emphasis on host factors and future directions. Journal of Orthopaedic Research 2012 30 4 541 546 2-s2.0-84857030815 10.1002/jor.21554
19. Bauer T. W., Particles and periimplant bone resorption. Clinical Orthopaedics and Related Research 2002 405 138 143 2-s2.0-0036908926 (Pubitemid 36008253)
20. Koreny T., Tunyogi-Csapó M., Gál I., Vermes C., Jacobs J. J., Glant T. T., The role of fibroblasts and fibroblast-derived factors in periprosthetic osteolysis. Arthritis and Rheumatism 2006 54 10 3221 3232 2-s2.0-33750287806 10.1002/art.22134 (Pubitemid 44622093)
21. Pioletti D. P., Kottelat A., The influence of wear particles in the expression of osteoclastogenesis factors by osteoblasts. Biomaterials 2004 25 27 5803 5808 2-s2.0-2542431059 10.1016/j.biomaterials.2004.01.053 (Pubitemid 38681164)
22. Okafor C. C., Haleem-Smith H., Laqueriere P., Manner P. A., Tuan R. S., Particulate endocytosis mediates biological responses of human mesenchymal stem cells to titanium wear debris. Journal of Orthopaedic Research 2006 24 3 461 473 2-s2.0-33645741765 10.1002/jor.20075 (Pubitemid 43773009)
23. Wang M. L., Nesti L. J., Tuli R., Lazatin J., Danielson K. G., Sharkey P. F., Tuan R. S., Titanium particles suppress expression of osteoblastic phenotype in human mesenchymal stem cells. Journal of Orthopaedic Research 2002 20 6 1175 1184 2-s2.0-0036435990 10.1016/S0736-0266(02)00076-1 (Pubitemid 35363974)
24. Haleem-Smith H., Argintar E., Bush C., Hampton D., Postma W. F., Chen F. H., Rimington T., Lamb J., Tuan R. S., Biological responses of human mesenchymal stem cells to titanium wear debris particles. Journal of Orthopaedic Research 2012 30 6 853 863 2-s2.0-84859631236 10.1002/jor.22002
25. Takagi M., Tamaki Y., Hasegawa H., Takakubo Y., Konttinen L., Tiainen V. M., Lappalainen R., Konttinen Y. T., Salo J., Toll-like receptors in the interface membrane around loosening total hip replacement implants. Journal of Biomedical Materials Research Part A 2007 81 4 1017 1026 2-s2.0-34249651241 10.1002/jbm.a.31235 (Pubitemid 46835099)
26. Hirayama T., Tamaki Y., Takakubo Y., Iwazaki K., Sasaki K., Ogino T., Goodman S. B., Konttinen Y. T., Takagi M., Toll-like receptors and their adaptors are regulated in macrophages after phagocytosis of lipopolysaccharide- coated titanium particles. Journal of Orthopaedic Research 2011 29 7 984 992 2-s2.0-79955909043 10.1002/jor.21369
27. Pearl J. I., Ma T., Irani A. R., Huang Z., Robinson W. H., Smith R. L., Goodman S. B., Role of the Toll-like receptor pathway in the recognition of orthopedic implant wear-debris particles. Biomaterials 2011 32 24 5535 5542 2-s2.0-79957896683 10.1016/j.biomaterials.2011.04.046
28. Lassus J., Waris V., Xu J. W., Li T. F., Hao J., Nietosvaara Y., Santavirta S., Konttinen Y. T., Increased interleukin-8 (IL-8) expression is related to aseptic loosening of total hip replacement. Archives of Orthopaedic and Trauma Surgery 2000 120 5-6 328 332 2-s2.0-0034060196 10.1007/s004020050475 (Pubitemid 30255857)
29. Mao X., Pan X., Peng X., Cheng T., Zhang X., Inhibition of titanium particle-induced inflammation by the proteasome inhibitor bortezomib in murine macrophage-like RAW 264.7 cells. Inflammation 2012 35 4 1411 1418
30. Takagi M., Toll-like receptora potent driving force behind rheumatoid arthritis. Journal of Clinical and Experimental Hematopathology 2011 51 2 77 92
31. Lemaitre B., Nicolas E., Michaut L., Reichhart J. M., Hoffmann J. A., The dorsoventral regulatory gene cassette spatzle/ Toll/Cactus controls the potent antifungal response in Drosophila adults. Cell 1996 86 6 973 983 2-s2.0-0030595339 10.1016/S0092-8674(00)80172-5 (Pubitemid 26336801)
32. Pasare C., Medzhitov R., Toll-like receptors: linking innate and adaptive immunity. Microbes and Infection 2004 6 15 1382 1387 2-s2.0-16644366474 10.1016/j.micinf.2004.08.018 (Pubitemid 41110581)
33. Pope R. M., Huang Q. Q., The role of Toll-like receptors in rheumatoid arthritis. Current Rheumatology Reports 2009 11 5 357 364 2-s2.0-70449625015 10.1007/s11926-009-0051-z
34. Akira S., Takeda K., Toll-like receptor signalling. Nature Reviews Immunology 2004 4 7 499 511 2-s2.0-3142724031 (Pubitemid 38931765)
35. Takeda K., Akira S., Toll-like receptors in innate immunity. International Immunology 2005 17 1 1 14 2-s2.0-12444341944 10.1093/intimm/dxh186
36. Chen G. Y., Nuez G., Sterile inflammation: sensing and reacting to damage. Nature Reviews Immunology 2010 10 12 826 837 2-s2.0-78649526394 10.1038/nri2873
37. Kondo T., Kawai T., Akira S., Dissecting negative regulation of Toll-like receptor signaling. Trends in Immunology 2012 33 9 449 458 2-s2.0-84865298775 10.1016/j.it.2012.05.002
38. Pajarinen J., Cenni E., Savarino L., Gomez-Barrena E., Tamaki Y., Takagi M., Salo J., Konttinen Y. T., Profile of toll-like receptor-positive cells in septic and aseptic loosening of total hip arthroplasty implants. Journal of Biomedical Materials Research Part A 2010 94 1 84 92 2-s2.0-77952686080 10.1002/jbm.a.32674
39. Lähdeoja T., Pajarinen J., Kouri V. P., Sillat T., Salo J., Konttinen Y. T., Toll-like receptors and aseptic loosening of hip endoprosthesisa potential to respond against danger signals? Journal of Orthopaedic Research 2010 28 2 184 190 2-s2.0-73849108436 10.1002/jor.20979
40. Hao H. N., Zheng B., Nasser S., Ren W., Latteier M., Wooley P., Morawa L., The roles of monocytic heat shock protein 60 and Toll-like receptors in the regional inflammation response to wear debris particles. Journal of Biomedical Materials Research Part A 2010 92 4 1373 1381 2-s2.0-77349095968 10.1002/jbm.a.32474
41. Greenfield E. M., Beidelschies M. A., Tatro J. M., Goldberg V. M., Hise A. G., Bacterial pathogen-associated molecular patterns stimulate biological activity of orthopaedic wear particles by activating cognate toll-like receptors. The Journal of Biological Chemistry 2010 285 42 32378 32384 2-s2.0-77957803209 10.1074/jbc.M110.136895
42. Pajarinen J., Mackiewicz Z., Pöllänen R., Takagi M., Epstein N. J., Ma T., Goodman S. B., Konttinen Y. T., Titanium particles modulate expression of Toll-like receptor proteins. Journal of Biomedical Materials Research Part A 2010 92 4 1528 1537 2-s2.0-77349112008 10.1002/jbm.a.32495
43. Tamaki Y., Takakubo Y., Goto K., Hirayama T., Sasaki K., Konttinen Y. T., Goodman S. B., Takagi M., Increased expression of toll-like receptors in aseptic loose periprosthetic tissues and septic synovial membranes around total hip implants. Journal of Rheumatology 2009 36 3 598 608 2-s2.0-65649109779 10.3899/jrheum.080390
44. Kumar H., Kawai T., Akira S., Toll-like receptors and innate immunity. Biochemical and Biophysical Research Communications 2009 388 4 621 625 2-s2.0-69949140723 10.1016/j.bbrc.2009.08.062
45. Ohashi K., Burkart V., Flohé S., Kolb H., Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex. The Journal of Immunology 2000 164 2 558 561 2-s2.0-0034650427 (Pubitemid 30043672)
46. Hou L., Sasaki H., Stashenko P., Toll-like receptor 4-deficient mice have reduced bone destruction following mixed anaerobic infection. Infection and Immunity 2000 68 8 4681 4687 2-s2.0-0033931495 10.1128/IAI.68.8.4681-4687.2000 (Pubitemid 30497741)
47. Zhuang L., Jung J. Y., Wang E. W., Houlihan P., Ramos L., Pashia M., Chole R. A., Pseudomonas aeruginosa lipopolysaccharide induces osteoclastogenesis through a toll-like receptor 4 mediated pathway in vitro and in vivo. Laryngoscope 2007 117 5 841 847 2-s2.0-34247895575 10.1097/MLG. 0b013e318033783a (Pubitemid 46699355)
48. Bi Y., Seabold J. M., Kaar S. G., Ragab A. A., Goldberg V. M., Anderson J. M., Greenfield E. M., Adherent endotoxin on orthopedic wear particles stimulates cytokine production and osteoclast differentiation. Journal of Bone and Mineral Research 2001 16 11 2082 2091 2-s2.0-0034782843 (Pubitemid 32995400)
49. Nalepka J. L., Lee M. J., Kraay M. J., Marcus R. E., Goldberg V. M., Chen X., Greenfield E. M., Lipopolysaccharide found in aseptic loosening of patients with inflammatory arthritis. Clinical Orthopaedics and Related Research 2006 451 229 235 2-s2.0-33749443907 10.1097/01.blo.0000224050.94248.38 (Pubitemid 44511333)
50. Maitra R., Clement C. C., Scharf B., Crisi G. M., Chitta S., Paget D., Purdue P. E., Cobelli N., Santambrogio L., Endosomal damage and TLR2 mediated inflammasome activation by alkane particles in the generation of aseptic osteolysis. Molecular Immunology 2009 47 2-3 175 184 2-s2.0-70450222517 10.1016/j.molimm.2009.09.023
51. Rollins B. J., Chemokines. Blood 1997 90 3 909 928 2-s2.0-0030825407 (Pubitemid 27314123)
52. Fernandez E. J., Lolis E., Structure, function, and inhibition of chemokines. Annual Review of Pharmacology and Toxicology 2002 42 469 499 2-s2.0-0036178483 10.1146/annurev.pharmtox.42.091901.115838 (Pubitemid 34160533)
53. Zlotnik A., Yoshie O., Chemokines: a new classification system and their role in immunity. Immunity 2000 12 2 121 127 2-s2.0-0034144269 (Pubitemid 30398626)
54. Pease J. E., Williams T. J., Chemokines and their receptors in allergic disease. Journal of Allergy and Clinical Immunology 2006 118 2 305 318 2-s2.0-33746568035 10.1016/j.jaci.2006.06.010 (Pubitemid 44142732)
55. Allen S. J., Crown S. E., Handel T. M., Chemokine: receptor structure, interactions, and antagonism. Annual Review of Immunology 2007 25 787 820 2-s2.0-34247855761 10.1146/annurev.immunol.24.021605.090529 (Pubitemid 46697924)
56. Lind M., Trindade M. C. D., Schurman D. J., Goodman S. B., Smith R. L., Monocyte migration inhibitory factor synthesis and gene expression in particle-activated macrophages. Cytokine 2000 12 7 909 913 2-s2.0-0033941244 10.1006/cyto.1999.0647 (Pubitemid 30479472)
57. Nakashima Y., Sun D. H., Trindade M. C. D., Chun L. E., Song Y., Goodman S. B., Schurman D. J., Maloney W. J., Smith R. L., Induction of macrophage C-C chemokine expression by titanium alloy and bone cement particles. Journal of Bone and Joint Surgery Series B 1999 81 1 155 162 2-s2.0-0032955730 10.1302/0301-620X.81B1.8884 (Pubitemid 29043430)
58. Yaszay B., Trindade M. C. D., Lind M., Goodman S. B., Smith R. L., Fibroblast expression of C-C chemokines in response to orthopaedic biomaterial particle challenge in vitro. Journal of Orthopaedic Research 2001 19 5 970 976 2-s2.0-0034866287 10.1016/S0736-0266(01)00003-1 (Pubitemid 32799090)
59. Ren P. G., Huang Z., Ma T., Biswal S., Smith R. L., Goodman S. B., Surveillance of systemic trafficking of macrophages induced by UHMWPE particles in nude mice by noninvasive imaging. Journal of Biomedical Materials Research Part A 2010 94 3 706 711 2-s2.0-77954809105 10.1002/jbm.a.32744
60. Ren P. G., Irani A., Huang Z., Ma T., Biswal S., Goodman S. B., Continuous infusion of UHMWPE particles induces increased bone macrophages and osteolysis. Clinical Orthopaedics and Related Research 2011 469 1 113 122 2-s2.0-78951473748 10.1007/s11999-010-1645-5
61. Remick D. G., Interleukin-8. Critical Care Medicine 2005 33 12, supplement S466 S467 2-s2.0-28944443012 10.1097/01.CCM.0000186783.34908.18 (Pubitemid 41785990)
62. Rose J. J., Foley J. F., Murphy P. M., Venkatesan S., On the mechanism and significance of ligand-induced internalization of human neutrophil chemokine receptors CXCR1 and CXCR2. The Journal of Biological Chemistry 2004 279 23 24372 24386 2-s2.0-2642513984 10.1074/jbc.M401364200 (Pubitemid 38725300)
63. Waugh D. J. J., Wilson C., The interleukin-8 pathway in cancer. Clinical Cancer Research 2008 14 21 6735 6741 2-s2.0-58149232586 10.1158/1078-0432.CCR- 07-4843
64. Shanbhag A. S., Jacobs J. J., Black J., Galante J. O., Glant T. T., Cellular mediators secreted by interfacial membranes obtained at revision total hip arthroplasty. Journal of Arthroplasty 1995 10 4 498 506 2-s2.0-0029051093 10.1016/S0883-5403(05)80152-4
65. Sabokbar A., Rushton N., Role of inflammatory mediators and adhesion molecules in the pathogenesis of aseptic loosening in total hip arthroplasties. Journal of Arthroplasty 1995 10 6 810 816 2-s2.0-0029558227 (Pubitemid 26003247)
66. Fritz E. A., Glant T. T., Vermes C., Jacobs J. J., Roebuck K. A., Titanium particles induce the immediate early stress responsive chemokines IL-8 and MCP-1 in osteoblasts. Journal of Orthopaedic Research 2002 20 3 490 498 2-s2.0-0036242444 10.1016/S0736-0266(01)00154-1 (Pubitemid 34461007)
67. Fritz E. A., Jacobs J. J., Glant T. T., Roebuck K. A., Chemokine IL-8 induction by particulate wear debris in osteoblasts is mediated by NF- κ B. Journal of Orthopaedic Research 2005 23 6 1249 1257 2-s2.0-27644463543 10.1016/j.orthres.2005.03.013 (Pubitemid 41554654)
68. Fritz E. A., Glant T. T., Vermes C., Jacobs J. J., Roebuck K. A., Chemokine gene activation in human bone marrow-derived osteoblasts following exposure to particulate wear debris. Journal of Biomedical Materials Research Part A 2006 77 1 192 201 2-s2.0-33645939840 10.1002/jbm.a.30609
69. Lochner K., Fritsche A., Jonitz A., Hansmann D., Mueller P., Mueller-Hilke B., Bader R., The potential role of human osteoblasts for periprosthetic osteolysis following exposure to wear particles. International Journal of Molecular Medicine 2011 28 6 1055 1063 2-s2.0-80053549892 10.3892/ijmm.2011.778
70. Kaufman A. M., Alabre C. I., Rubash H. E., Shanbhag A. S., Human macrophage response to UHMWPE, TiAlV, CoCr, and alumina particles: analysis of multiple cytokines using protein arrays. Journal of Biomedical Materials Research Part A 2008 84 2 464 474 2-s2.0-38049022139 10.1002/jbm.a.31467
71. Valente A. J., Graves D. T., Vialle-Valentin C. E., Delgado R., Schwartz C. J., Purification of a monocyte chemotactic factor secreted by nonhuman primate vascular cells in culture. Biochemistry 1988 27 11 4162 4168 2-s2.0-0024300821
72. Matsushima K., Larsen C. G., DuBois G. C., Oppenheim J. J., Purification and characterization of a novel monocyte chemotactic and activating factor produced by a human myelomonocytic cell line. The Journal of Experimental Medicine 1989 169 4 1485 1490 2-s2.0-0024508563 (Pubitemid 19104979)
73. Charo I. F., Taubman M. B., Chemokines in the pathogenesis of vascular disease. Circulation Research 2004 95 9 858 866 2-s2.0-7244242357 10.1161/01.RES.0000146672.10582.17 (Pubitemid 39435000)
74. Balkwill F., Cancer and the chemokine network. Nature Reviews Cancer 2004 4 7 540 550 2-s2.0-3042822267 (Pubitemid 38868623)
75. Lu Y., Xiao G., Galson D. L., Nishio Y., Mizokami A., Keller E. T., Yao Z., Zhang J., PTHrP-induced MCP-1 production by human bone marrow endothelial cells and osteoblasts promotes osteoclast differentiation and prostate cancer cell proliferation and invasion in vitro. International Journal of Cancer 2007 121 4 724 733 2-s2.0-34547111029 10.1002/ijc.22704 (Pubitemid 47106200)
76. Li X., Qin L., Bergenstock M., Bevelock L. M., Novack D. V., Partridge N. C., Parathyroid hormone stimulates osteoblastic expression of MCP-1 to recruit and increase the fusion of pre/osteoclasts. The Journal of Biological Chemistry 2007 282 45 33098 33106 2-s2.0-36348953061 10.1074/jbc.M611781200 (Pubitemid 350159306)
77. Trindade M. C. D., Schurman D. J., Maloney W. J., Goodman S. B., Smith R. L., G-protein activity requirement for polymethylmethacrylate and titanium particle-induced fibroblast interleukin-6 and monocyte chemoattractant protein-1 release in vitro. Journal of Biomedical Materials Research 2000 51 3 360 368 2-s2.0-0034609617 10.1002/1097-4636(20000905)51:3360::AID-JBM9>3.0.CO;2-E (Pubitemid 30452138)
78. Dasa V., Kramer J. M., Gaffen S. L., Kirkwood K. L., Mihalko W. M., Is monocyte chemotactic protein 1 elevated in aseptic loosening of TKA?: a pilot study. Clinical Orthopaedics and Related Research 2012 470 7 1879 1884 2-s2.0-84864278704 10.1007/s11999-011-2191-5
79. Huang Z., Ma T., Ren P. G., Smith R. L., Goodman S. B., Effects of orthopedic polymer particles on chemotaxis of macrophages and mesenchymal stem cells. Journal of Biomedical Materials Research Part A 2010 94 4 1264 1269 2-s2.0-77956453902 10.1002/jbm.a.32803
80. Ramos C. D. L., Canetti C., Souto J. T., Silva J. S., Hogaboam C. M., Ferreira S. H., Cunha F. Q., MIP-1 α [CCL3] acting on the CCR1 receptor mediates neutrophil migration in immune inflammation via sequential release of TNF- α and LTB4. Journal of Leukocyte Biology 2005 78 1 167 177 2-s2.0-22144465474 10.1189/jlb.0404237 (Pubitemid 40979955)
81. Maurer M., Von Stebut E., Macrophage inflammatory protein-1. International Journal of Biochemistry and Cell Biology 2004 36 10 1882 1886 2-s2.0-2942559019 10.1016/j.biocel.2003.10.019 (Pubitemid 38760018)
82. Gibon E., Ma T., Ren P.-G., Fritton K., Biswal S., Yao Z., Smith L., Goodman S. B., Selective inhibition of the MCP-1-CCR2 ligand-receptor axis decreases systemic trafficking of macrophages in the presence of UHMWPE particles. Journal of Orthopaedic Research 2012 30 4 547 553 2-s2.0-84857030878 10.1002/jor.21548
83. Cadosch D., Gautschi O. P., Chan E., Simmen H. P., Filgueira L., Titanium induced production of chemokines CCL17/TARC and CCL22/MDC in human osteoclasts and osteoblasts. Journal of Biomedical Materials Research Part A 2010 92 2 475 483 2-s2.0-75149134683 10.1002/jbm.a.32390