Intestinal Flagellate And Ciliate Infections

Tropical Infectious Diseases

Volumn , Issue , 2011, Pages 623-632

  Hill, David R ^a,b   Nash, Theodore E ^c  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84868675265     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-7020-3935-5.00093-8     Document Type: Chapter

References (362)

1. Garcia LS Classification of human parasites, vectors, and similar organisms. Clin Infect Dis 1999, 29:734.
2. Meyer EA Taxonomy and nomenclature. Giardiasis 1990, 51. Elsevier Science, Amsterdam. E.A. Meyer (Ed.).
3. Morrison HG, McArthur AG, Gillin FD, et al. Genomic minimalism in the early diverging intestinal parasite Giardia lamblia. Science 2007, 317:1921.
4. Palm D, Weiland M, McArthur AG, et al. Developmental changes in the adhesive disk during Giardia differentiation. Mol Biochem Parasitol 2005, 141:199.
5. Nohynkova E, Tumova P, Kulda J Cell division of Giardia intestinalis: flagellar developmental cycle involves transformation and exchange of flagella between mastigonts of a diplomonad cell. Eukaryot Cell 2006, 5:753.
6. Lauwaet T, Davids BJ, Reiner DS, et al. Encystation of Giardia lamblia: a model for other parasites. Curr Opin Microbiol 2007, 10:554.
7. Yu LZ, Birky CW, Adam RD The two nuclei of Giardia each have complete copies of the genome and are partitioned equationally at cytokinesis. Eukaryot Cell 2002, 1:191.
8. Teodorovic S, Braverman JM, Elmendorf HG Unusually low levels of genetic variation among Giardia lamblia isolates. Eukaryot Cell 2007, 6:1421.
9. Elmendorf HG, Singer SM, Pierce J, et al. Initiator and upstream elements in the alpha2-tubulin promoter of Giardia lamblia. Mol Biochem Parasitol 2001, 113:157.
10. Davis-Hayman SR, Nash TE Genetic manipulation of Giardia lamblia. Mol Biochem Parasitol 2002, 122:1.
11. Yee J, Mowatt MR, Dennis PP, et al. Transcriptional analysis of the glutamate dehydrogenase gene in the primitive eukaryote, Giardia lamblia. Identification of a primordial gene promoter. J Biol Chem 2000, 275:11432.
12. Adam RD Biology of Giardia lamblia. Clin Micro Rev 2001, 14:447.
13. Lloyd D, Harris JC, Maroulis S, et al. The "primitive" microaerophile Giardia intestinalis (syn. lamblia, duodenalis) has specialized membranes with electron transport and membrane-potential-generating functions. Microbiology 2002, 148:1349.
14. Roger AJ, Svard SG, Tovar J, et al. A mitochondrial-like chaperonin 60 gene in Giardia lamblia: evidence that diplomonads once harbored an endosymbiont related to the progenitor of mitochondria. Proc Natl Acad Sci USA 1998, 95:229.
15. Tovar J, Leon-Avila G, Sanchez LB, et al. Mitochondrial remnant organelles of Giardia function in iron-sulphur protein maturation. Nature 2003, 426:172.
16. Knight J Giardia: not so special, after all?. Nature 2004, 429:236.
17. Graczyk TK Is Giardia a living fossil?. Trends Parasitol 2005, 21:104.
18. Dacks JB, Walker G, Field MC Implications of the new eukaryotic systematics for parasitologists. Parasitol Int 2008, 57:97.
19. Bernander R, Palm JE, Svard SG Genome ploidy in different stages of the Giardia lamblia life cycle. Cell Microbiol 2001, 3:55.
20. Lanfredi-Rangel A, Attias M, de Carvalho TM, et al. The peripheral vesicles of trophozoites of the primitive protozoan Giardia lamblia may correspond to early and late endosomes and to lysosomes. J Struct Biol 1998, 123:225.
21. de Souza W, Sant'Anna C, Cunha-e-Silva NL Electron microscopy and cytochemistry analysis of the endocytic pathway of pathogenic protozoa. Prog Histochem Cytochem 2009, 44:67.
22. Benchimol M Mitosis in Giardia lamblia: multiple modes of cytokinesis. Protist 2004, 155:33.
23. Tumova P, Kulda J, Nohynkova E Cell division of Giardia intestinalis: assembly and disassembly of the adhesive disc, and the cytokinesis. Cell Motil Cytoskeleton 2007, 64:288.
24. Nash TE, McCutchan T, Keister D, et al. Restriction-endonuclease analysis of DNA from 15 Giardia isolates obtained from humans and animals. J Infect Dis 1985, 152:64.
25. Wielinga CM, Thompson RC Comparative evaluation of Giardia duodenalis sequence data. Parasitology 2007, 134:1795.
26. Monis PT, Caccio SM, Thompson RC Variation in Giardia: towards a taxonomic revision of the genus. Trends Parasitol 2009, 25:93.
27. Caccio SM, Beck R, Lalle M, et al. Multilocus genotyping of Giardia duodenalis reveals striking differences between assemblages A and B. Int J Parasitol 2008.
28. Steuart RF Proteomic analysis of Giardia: studies from the pre- and post-genomic era. Exp Parasitol 2010, 124:26.
29. Byrd LG, Conrad JT, Nash TE Giardia lamblia infections in adult mice. Infect Immun 1994, 62:3583.
30. Nash TE Surface antigenic variation in Giardia lamblia. Mol Microbiol 2002, 45:585.
31. Aggarwal A, Nash TE Comparison of two antigenically distinct Giardia lamblia isolates in gerbils. Am J Trop Med Hyg 1987, 36:325.
32. Xiao L, Fayer R Molecular characterisation of species and genotypes of Cryptosporidium and Giardia and assessment of zoonotic transmission. Int J Parasitol 2008, 38:1239.
33. Baruch AC, Isaac-Renton J, Adam RD The molecular epidemiology of Giardia lamblia: a sequence-based approach. J Infect Dis 1996, 174:233.
34. Appelbee AJ, Thompson RC, Olson ME Giardia and Cryptosporidium in mammalian wildlife - current status and future needs. Trends Parasitol 2005, 21:370.
35. Thompson RC, Palmer CS, O'Handley R The public health and clinical significance of Giardia and Cryptosporidium in domestic animals. Vet J 2008, 177:18.
36. Gillin FD, Reiner DS, Gault MJ, et al. Encystation and expression of cyst antigens by Giardia lamblia in vitro. Science 1987, 235:1040.
37. Schupp DG, Januschka MM, Sherlock LAF, et al. Production of viable Giardia cysts in vitro: determination by fluorogenic dye staining, excystation, and animal infectivity in the mouse and mongolian gerbil. Gastroenterology 1988, 95:1.
38. Lujan HD, Mowatt MR, Byrd LG, et al. Cholesterol starvation induces differentiation of the intestinal parasite Giardia lamblia. Proc Natl Acad Sci USA 1996, 93:7628.
39. Erlandsen SL, Macechko PT, van Keulen H, et al. Formation of the Giardia cyst wall: studies on extracellular assembly using immunogold labeling and high resolution field emission SEM. J Eukaryot Microbiol 1996, 43:416.
40. Gottig N, Elias EV, Quiroga R, et al. Active and passive mechanisms drive secretory granule biogenesis during differentiation of the intestinal parasite Giardia lamblia. J Biol Chem 2006, 281:18156.
41. DuBois KN, Abodeely M, Sakanari J, et al. Identification of the major cysteine protease of Giardia and its role in encystation. J Biol Chem 2008, 283:18024.
42. Midlej V, Benchimol M Giardia lamblia behavior during encystment: how morphological changes in shape occur. Parasitol Int 2009, 58:72.
43. Clark CG, Diamond LS Methods for cultivation of luminal parasitic protists of clinical importance. Clin Microbiol Rev 2002, 15:329.
44. 2-scavenging flavodiiron protein in the human parasite Giardia intestinalis. J Biol Chem 2008, 283:4061.
45. Lujan HD, Mowatt MR, Chen GZ, et al. Isoprenylation of proteins in the protozoan Giardia lamblia. Mol Biochem Parasitol 1995, 72:121.
46. Svard SG, Hagblom P, Palm JE Giardia lamblia - a model organism for eukaryotic cell differentiation. FEMS Microbiol Lett 2003, 218:3.
47. Elmendorf HG, Singer SM, Nash TE Targeting of proteins to the nuclei of Giardia lamblia. Mol Biochem Parasitol 2000, 106:315.
48. Lujan HD, Marotta A, Mowatt MR, et al. Developmental induction of Golgi structure and function in the primitive eukaryote Giardia lamblia. J Biol Chem 1995, 270:4612.
49. Hehl AB, Marti M Secretory protein trafficking in Giardia intestinalis. Mol Microbiol 2004, 53:19.
50. Poxleitner MK, Carpenter ML, Mancuso JJ, et al. Evidence for karyogamy and exchange of genetic material in the binucleate intestinal parasite Giardia intestinalis. Science 2008, 319:1530.
51. Kulakova L, Singer SM, Conrad J, et al. Epigenetic mechanisms are involved in the control of Giardia lamblia antigenic variation. Mol Microbiol 2006, 61:1533.
52. Prucca CG, Slavin I, Quiroga R, et al. Antigenic variation in Giardia lamblia is regulated by RNA interference. Nature 2008, 456:750.
53. Mowatt MR, Nguyen BYT, Conrad JT, et al. Size heterogeneity among antigenically related Giardia lamblia variant-specific surface proteins is due to differences in tandem repeat copy number. Infect Immun 1994, 62:1213.
54. Nash TE, Conrad JT, Mowatt MR Giardia lamblia: identification and characterization of a variant-specific surface protein gene family. J Eukaryot Microbiol 1995, 42:604.
55. Nash TE, Mowatt MR Variant-specific surface proteins of Giardia lamblia are zinc-binding proteins. Proc Natl Acad Sci USA 1993, 90:5489.
56. Zhang Y-Y, Aley SB, Stanley SL, et al. Cysteine-dependent zinc binding by membrane proteins of Giardia lamblia. Infect Immun 1993, 61:520.
57. Nash TE, Merritt JW, Conrad JT Isolate and epitope variability in susceptibility of Giardia lamblia to intestinal proteases. Infect Immun 1991, 59:1334.
58. Nash TE, Herrington DA, Levine MM, et al. Antigenic variation of Giardia lamblia in experimental human infections. J Immunol 1990, 144:4362.
59. Singer SM, Elmendorf HG, Conrad JT, et al. Biological selection of variant-specific surface proteins in Giardia lamblia. J Infect Dis 2001, 183:119.
60. Yoder JS, Harral C, Beach MJ Giardiasis surveillance - United States, 2006-2008. MMWR Surveill Summ 2010, 59(SS-6):15.
61. Dib HH, Lu SQ, Wen SF Prevalence of Giardia lamblia with or without diarrhea in South East, South East Asia and the Far East. Parasitol Res 2008, 103:239.
62. Kappus KD, Lundgren RGJ, Juranek DD, et al. Intestinal parasitism in the United States: update on a continuing problem. Am J Trop Med Hyg 1994, 50:705.
63. Moore GT, Cross WM, McGuire D, et al. Epidemic giardiasis at a ski resort. N Engl J Med 1969, 281:402.
64. Craun GF, Calderon RL, Craun MF Outbreaks associated with recreational water in the United States. Int J Environ Health Res 2005, 15:243.
65. Nygard K, Schimmer B, Sobstad O, et al. A large community outbreak of waterborne giardiasis-delayed detection in a non-endemic urban area. BMC Public Health 2006, 6:141.
66. Karanis P, Kourenti C, Smith H Waterborne transmission of protozoan parasites: a worldwide review of outbreaks and lessons learnt. J Water Health 2007, 5:1.
67. O'Reilly CE, Bowen AB, Perez NE, et al. A waterborne outbreak of gastroenteritis with multiple etiologies among resort island visitors and residents: Ohio, 2004. Clin Infect Dis 2007, 44:506.
68. Eisenstein L, Bodager D, Ginzl D Outbreak of giardiasis and cryptosporidiosis associated with a neighborhood interactive water fountain - Florida, 2006. J Environ Health 2008, 71:18.
69. Yoder JS, Hlavsa MC, Craun GF, et al. Surveillance for waterborne disease and outbreaks associated with recreational water use and other aquatic facility-associated health events - United States, 2005-2006. MMWR Surveill Summ 2008, 57(SS-9):1.
70. Yoder J, Roberts V, Craun GF, et al. Surveillance for waterborne disease and outbreaks associated with drinking water and water not intended for drinking - United States, 2005-2006. MMWR Surveill Summ 2008, 57(SS-9):39.
71. Schuster CJ, Ellis AG, Robertson WJ, et al. Infectious disease outbreaks related to drinking water in Canada, 1974-2001. Can J Public Health 2005, 96:254.
72. Smith A, Reacher M, Smerdon W, et al. Outbreaks of waterborne infectious intestinal disease in England and Wales, 1992-2003. Epidemiol Infect 2006, 134:1141.
73. Stuart JM, Orr HJ, Warburton FG, et al. Risk factors for sporadic giardiasis: a case-control study in southwestern England. Emerg Infect Dis 2003, 9:229.
74. Katz DE, Heisey-Grove D, Beach M, et al. Prolonged outbreak of giardiasis with two modes of transmission. Epidemiol Infect 2006, 134:935.
75. deRegnier DP, Cole L, Schupp DG, et al. Viability of Giardia cysts suspended in lake, river, and tap water. Appl Environ Microbiol 1989, 55:1223.
76. Addiss DG, Stewart JM, Finton RJ, et al. Giardia lamblia and Cryptosporidium infections in child day-care centers in Fulton County, Georgia. Pediatr Infect Dis J 1991, 10:907.
77. Thompson SC Giardia lamblia in children and the child care setting: a review of the literature. J Paediatr Child Health 1994, 30:202.
78. Polis MA, Tuazon CU, Alling DW, et al. Transmission of Giardia lamblia from a day care center to the community. Am J Public Health 1986, 76:1142.
79. Overturf GD Endemic giardiasis in the United States - role of the daycare center. Clin Infect Dis 1994, 18:764.
80. Laupland KB, Church DL Population-based laboratory surveillance for Giardia sp. and Cryptosporidium sp. infections in a large Canadian health region. BMC Infect Dis 2005, 5:72.
81. Pollock KG, Smith HV, Young D, et al. Giardia surveillance in Scotland, 1988-2003. Eur J Clin Microbiol Infect Dis 2005, 24:571.
82. Gilman RH, Brown KH, Visvesvara GS, et al. Epidemiology and serology of Giardia lamblia in a developing country: Bangladesh. Trans R Soc Trop Med Hyg 1985, 79:469.
83. Farthing MJG, Mata L, Urrutia JJ, et al. Natural history of Giardia infection of infants and children in rural Guatemala and its impact on physical growth. Am J Clin Nutr 1986, 43:395.
84. Fraser D, Dagan R, Naggan L, et al. Natural history of Giardia lamblia and Cryptosporidium infections in a cohort of Israeli Bedouin infants: a study of a population in transition. Am J Trop Med Hyg 1997, 57:544.
85. Berkman DS, Lescano AG, Gilman RH, et al. Effects of stunting, diarrhoeal disease, and parasitic infection during infancy on cognition in late childhood: a follow-up study. Lancet 2002, 359:564.
86. Prado MS, Cairncross S, Strina A, et al. Asymptomatic giardiasis and growth in young children; a longitudinal study in Salvador. Brazil. Parasitology 2005, 131:51.
87. Hasan KZ, Pathela P, Alam K, et al. Aetiology of diarrhoea in a birth cohort of children aged 0-2 year(s) in rural Mirzapur, Bangladesh. J Health Popul Nutr 2006, 24:25.
88. Al-Mekhlafi MS, Azlin M, Nor Aini U, et al. Giardiasis as a predictor of childhood malnutrition in Orang Asli children in Malaysia. Trans R Soc Trop Med Hyg 2005, 99:686.
89. Carvalho-Costa FA, Goncalves AQ, Lassance SL, et al. Giardia lamblia and other intestinal parasitic infections and their relationships with nutritional status in children in Brazilian Amazon. Rev Inst Med Trop Sao Paulo 2007, 49:147.
90. Hollm-Delgado MG, Gilman RH, Bern C, et al. Lack of an adverse effect of Giardia intestinalis infection on the health of Peruvian children. Am J Epidemiol 2008, 168:647.
91. Laughon BE, Druckman DA, Vernon A, et al. Prevalence of enteric pathogens in homosexual men with and without acquired immunodeficiency syndrome. Gastroenterology 1988, 94:984.
92. Esfandiari A, Swartz J, Teklehaimanot S Clustering of giardiosis among AIDS patients in Los Angeles County. Cell Mol Biol 1997, 43:1077.
93. Mintz ED, Hudson-Wragg M, Mshar P, et al. Foodborne giardiasis in a corporate office setting. J Infect Dis 1993, 167:250.
94. Lynch M, Painter J, Woodruff R, et al. Surveillance for foodborne-disease outbreaks - United States, 1998-2002. MMWR Surveill Summ 2006, 55:1.
95. Rendtorff RC The experimental transmission of human intestinal protozoan parasites: II. Giardia lamblia cysts given in capsules. Am J Hyg 1954, 59:209.
96. Gray SF, Gunnell DJ, Peters TJ Risk factors for giardiasis: a case-control study in Avon and Somerset. Epidemiol Infect 1995, 113:95.
97. Snel SJ, Baker MG, Kamalesh V, et al. A tale of two parasites: the comparative epidemiology of cryptosporidiosis and giardiasis. Epidemiol Infect 2009, 137:1641.
98. Jelinek T, Loscher T Epidemiology of giardiasis in German travelers. J Travel Med 2000, 7:70.
99. Ekdahl K, Andersson Y Imported giardiasis: impact of international travel, immigration, and adoption. Am J Trop Med Hyg 2005, 72:825.
100. Isaac-Renton JL, Cordeiro C, Sarafis K, et al. Characterization of Giardia duodenalis isolates from a waterborne outbreak. J Infect Dis 1993, 167:431.
101. Caccio SM, Ryan U Molecular epidemiology of giardiasis. Mol Biochem Parasitol 2008, 160:75.
102. Hetsko ML, McCaffery JM, Svard SG, et al. Cellular and transcriptional changes during excystation of Giardia lamblia in vitro. Exp Parasitol 1998, 88:172.
103. Weiland ME, Palm JE, Griffiths WJ, et al. Characterisation of alpha-1 giardin: an immunodominant Giardia lamblia annexin with glycosaminoglycan-binding activity. Int J Parasitol 2003, 33:1341.
104. Jenkins M, O'Brien CN, Murphy C, et al. Antibodies to the ventral disc protein delta-giardin prevent in vitro binding of Giardia lamblia trophozoites. J Parasitol 2009, 95:895.
105. Hernandez-Sanchez J, Linan RF, Salinas-Tobon M del R, et al. Giardia duodenalis: adhesion-deficient clones have reduced ability to establish infection in Mongolian gerbils. Exp Parasitol 2008, 119:364.
106. Leitch GJ, Visvesvara GS, Wahlquist SP, et al. Dietary fiber and giardiasis: dietary fiber reduces rate of intestinal infection by Giardia lamblia in the gerbil. Am J Trop Med Hyg 1989, 41:512.
107. Grant J, Mahanty S, Khadir A, et al. Wheat germ supplement reduces cyst and trophozoite passage in people with giardiasis. Am J Trop Med Hyg 2001, 65:705.
108. Chin AC, Teoh DA, Scott KG, et al. Strain-dependent induction of enterocyte apoptosis by Giardia lamblia disrupts epithelial barrier function in a caspase-3-dependent manner. Infect Immun 2002, 70:3673.
109. Panaro MA, Cianciulli A, Mitolo V, et al. Caspase-dependent apoptosis of the HCT-8 epithelial cell line induced by the parasite Giardia intestinalis. FEMS Immunol Med Microbiol 2007, 51:302.
110. Buret AG Pathophysiology of enteric infections with Giardia duodenalis. Parasite 2008, 15:261.
111. Troeger H, Epple HJ, Schneider T, et al. Effect of chronic Giardia lamblia infection on epithelial transport and barrier function in human duodenum. Gut 2007, 56:328.
112. Yu LC, Huang CY, Kuo WT, et al. SGLT-1-mediated glucose uptake protects human intestinal epithelial cells against Giardia duodenalis-induced apoptosis. Int J Parasitol 2008, 38:923.
113. Li E, Zhou P, Singer SM Neuronal nitric oxide synthase is necessary for elimination of Giardia lamblia infections in mice. J Immunol 2006, 176:516.
114. Eckmann L, Laurent F, Langford TD, et al. Nitric oxide production by human intestinal epithelial cells and competition for arginine as potential determinants of host defense against the lumen-dwelling pathogen Giardia lamblia. J Immunol 2000, 164:1478.
115. Ringqvist E, Palm JE, Skarin H, et al. Release of metabolic enzymes by Giardia in response to interaction with intestinal epithelial cells. Mol Biochem Parasitol 2008, 159:85.
116. Nash TE, Herrington DA, Losonsky GA, et al. Experimental human infections with Giardia lamblia. J Infect Dis 1987, 156:974.
117. Yardley JH, Takano J, Hendrix TR Epithelial and other mucosal lesions of the jejunum in giardiasis. Jejunal biopsy studies. Bull Johns Hopkins Hosp 1964, 115:389.
118. Duncombe VM, Bolin TD, Davis AE, et al. Histopathology in giardiasis: a correlation with diarrhea. Aust N Z J Med 1978, 8:392.
119. Hjelt K, Pœrregaard A, Krasilnikoff PA Giardiasis causing chronic diarrhoea in suburban Copenhagen: incidence, physical growth, clinical symptoms and small intestinal abnormality. Acta Pediatri 1992, 81:881.
120. Ridley MJ, Ridley DS Serum antibodies and jejunal histology in giardiasis. J Clin Pathol 1976, 29:30.
121. Oberhuber G, Kastner N, Stolte M Giardiasis: a histologic analysis of 567 cases. Scand J Infect Dis 1997, 32:48.
122. Chen XM, Keithly JS, Paya CV, et al. Cryptosporidiosis. N Engl J Med 2002, 346:1723.
123. Astiazaran-Garcia H, Espinosa-Cantellano M, Castanon G, et al. Giardia lamblia: effect of infection with symptomatic and asymptomatic isolates on the growth of gerbils (Meriones unguiculatus). Exp Parasitol 2000, 95:128.
124. Paintlia AS, Descoteaux S, Spencer B, et al. Giardia lamblia groups A and B among young adults in India. Clin Infect Dis 1998, 26:190.
125. Sahagun J, Clavel A, Goni P, et al. Correlation between the presence of symptoms and the Giardia duodenalis genotype. Eur J Clin Microbiol Infect Dis 2008, 27:81.
126. Haque R, Mondal D, Karim A, et al. Prospective case-control study of the association between common enteric protozoal parasites and diarrhea in Bangladesh. Clin Infect Dis 2009, 48:1191.
127. Ajjampur SS, Sankaran P, Kannan A, et al. Giardia duodenalis assemblages associated with diarrhea in children in South India identified by PCR-RFLP. Am J Trop Med Hyg 2009, 80:16.
128. Homan WL, Mank TG Human giardiasis: genotype linked differences in clinical symptomatology. Int J Parasitol 2001, 31:822.
129. Gelanew T, Lalle M, Hailu A, et al. Molecular characterization of human isolates of Giardia duodenalis from Ethiopia. Acta Trop 2007, 102:92.
130. Cedillo-Rivera R, Darby JM, Enciso-Moreno JA, et al. Genetic homogeneity of axenic isolates of Giardia intestinalis derived from acute and chronically infected individuals in Mexico. Parasitol Res 2003, 90:119.
131. Robertson LJ, Forberg T, Hermansen L, et al. Molecular characterisation of Giardia isolates from clinical infections following a waterborne outbreak. J Infect 2007, 55:79.
132. Yason JA, Rivera WL Genotyping of Giardia duodenalis isolates among residents of slum area in Manila, Philippines. Parasitol Res 2007, 101:681.
133. Kohli A, Bushen OY, Pinkerton RC, et al. Giardia duodenalis assemblage, clinical presentation and markers of intestinal inflammation in Brazilian children. Trans R Soc Trop Med Hyg 2008, 102:718.
134. Perez Cordon G, Cordova Paz Soldan O, Vargas Vasquez F, et al. Prevalence of enteroparasites and genotyping of Giardia lamblia in Peruvian children. Parasitol Res 2008, 103:459.
135. Lebbad M, Ankarklev J, Tellez A, et al. Dominance of Giardia assemblage B in Leon, Nicaragua. Acta Trop 2008, 106:44.
136. Roxström-Lindquist K, Palm D, Reiner D, et al. Giardia immunity - an update. Trends Parasitol 2006, 22:26.
137. Roberts-Thomson IC, Stevens DP, Mahmoud AAF, et al. Acquired resistance to infection in an animal model of giardiasis. J Immunol 1976, 117:2036.
138. Roberts-Thomson IC, Stevens DP, Mahmoud AAF, et al. Giardiasis in the mouse: an animal model. Gastroenterology 1976, 71:57.
139. Isaac-Renton JL, Lewis LF, Ong CS, et al. A second community outbreak of waterborne giardiasis in Canada and serological investigation of patients. Trans R Soc Trop Med Hyg 1994, 88:395.
140. Istre GR, Dunlop TS, Gaspard B, et al. Waterborne giardiasis at a mountain resort: evidence for acquired immunity. Am J Public Health 1984, 74:602.
141. Miotti PG, Gilman RH, Santosham M, et al. Age-related rate of seropositivity of antibody to Giardia lamblia in four diverse populations. J Clin Microbiol 1986, 24:972.
142. Cook DM, Swanson RC, Eggett DL, et al. A retrospective analysis of prevalence of gastrointestinal parasites among school children in the Palajunoj Valley of Guatemala. J Health Popul Nutr 2009, 27:31.
143. Isaac-Renton J, Blatherwick J, Bowie WR, et al. Epidemic and endemic seroprevalence of antibodies to Cryptosporidium and Giardia in residents of three communities with different drinking water supplies. Am J Trop Med Hyg 1999, 60:578.
144. Ljungström I, Castor B Immune response to Giardia lamblia in a water-borne outbreak of giardiasis in Sweden. J Med Micro 1992, 36:347.
145. Soliman MM, Taghi-Kilani R, Abou-Shady AF, et al. Comparison of serum antibody response to Giardia lamblia of symptomatic and asymptomatic patients. Am J Trop Med Hyg 1998, 58:232.
146. Palm JE, Weiland ME, Griffiths WJ, et al. Identification of immunoreactive proteins during acute human giardiasis. J Infect Dis 2003, 187:1849.
147. Rodriguez OL, Hagel I, Gonzalez Y, et al. Secretory IgA antibody responses in Venezuelan children infected with Giardia duodenalis. J Trop Pediatr 2004, 50:68.
148. Hill DR, Burge JJ, Pearson RD Susceptibility of Giardia lamblia trophozoites to the lethal effect of human serum. J Immunol 1984, 132:2046.
149. Stager S, Felleisen R, Gottstein B, et al. Giardia lamblia variant surface protein H7 stimulates a heterogeneous repertoire of antibodies displaying differential cytological effects on the parasite. Mol Biochem Parasitol 1997, 85:113.
150. Snider DP, Underdown BJ Quantitative and temporal analyses of murine antibody response in serum and gut secretions to infection with Giardia muris. Infect Immun 1986, 52:271.
151. Gottstein B, Deplazes P, Tanner I In vitro synthesized immunoglobulin A from nu/+ and reconstituted nu/nu mice against a dominant surface antigen of Giardia lamblia. Parasitol Res 1993, 79:644.
152. Andrews JS, Hewlett EL Protection against infection with Giardia muris by milk containing antibody to Giardia. J Infect Dis 1981, 143:242.
153. Snider DP, Gordon J, McDermott MR, et al. Chronic Giardia muris infection in anti-IgM-treated mice. J Immunol 1985, 134:4153.
154. Davids BJ, Palm JE, Housley MP, et al. Polymeric immunoglobulin receptor in intestinal immune defense against the lumen-dwelling protozoan parasite Giardia. J Immunol 2006, 177:6281.
155. Langford TD, Housley MP, Boes M, et al. Central importance of immunoglobulin A in host defense against Giardia spp. Infect Immun 2002, 70:11.
156. Singer SM, Nash TE T-cell-dependent control of acute Giardia lamblia infections in mice. Infect Immun 2000, 68:170.
157. Roberts-Thomson IC, Mitchell GF Giardiasis in mice: I. Prolonged infections in certain mouse strains and hypothymic (nude) mice. Gastroenterology 1978, 75:42.
158. Stevens DP, Frank DM, Mahmoud AAF Thymus dependency of host resistance to Giardia muris infection: studies in nude mice. J Immunol 1978, 120:680.
159. + T lymphocytes in jejunal mucosal injury during murine giardiasis. Infect Immun 2004, 72:3536.
160. Heyworth MF, Carlson JR, Ermak TH Clearance of Giardia muris infection requires helper/inducer T lymphocytes. J Exp Med 1987, 165:1743.
161. Bienz M, Dai WJ, Welle M, et al. Interleukin-6-deficient mice are highly susceptible to Giardia lamblia infection but exhibit normal intestinal immunoglobulin A responses against the parasite. Infect Immun 2003, 71:1569.
162. Zhou P, Li E, Zhu N, et al. Role of interleukin-6 in the control of acute and chronic Giardia lamblia infections in mice. Infect Immun 2003, 71:1566.
163. Li E, Zhou P, Petrin Z, et al. Mast cell-dependent control of Giardia lamblia infections in mice. Infect Immun 2004, 72:6642.
164. Andersen YS, Gillin FD, Eckmann L Adaptive immunity-dependent intestinal hypermotility contributes to host defense against Giardia spp. Infect Immun 2006, 74:2473.
165. Li E, Zhao A, Shea-Donohue T, et al. Mast cell-mediated changes in smooth muscle contractility during mouse giardiasis. Infect Immun 2007, 75:4514.
166. Gottstein B, Harriman GR, Conrad JT, et al. Antigenic variation in Giardia lamblia: cellular and humoral immune response in a mouse. Parasite Immunol 1990, 12:659.
167. Hill DR Lymphocyte proliferation in Peyer's patches of Giardia muris infected mice. Infect Immun 1990, 58:2683.
168. Gottstein B, Stocks NI, Shearer GM, et al. Human cellular immune response to Giardia lamblia. Infection 1991, 19:421.
169. Owen RL, Allen CL, Stevens DP Phagocytosis of Giardia muris by macrophages in Peyer's patch epithelium in mice. Infect Immun 1981, 33:591.
170. Hill DR, Pearson RD Ingestion of Giardia lamblia trophozoites by human mononuclear phagocytes. Infect Immun 1987, 55:3155.
171. Hill DR, Pohl R Ingestion of Giardia lamblia trophozoites by murine Peyer's patch macrophages. Infect Immun 1990, 58:3202.
172. Ament ME, Rubin CE Relation of giardiasis to abnormal intestinal structure and function in gastrointestinal immunodeficiency syndromes. Gastroenterology 1972, 62:216.
173. Hartong WA, Gourley WK, Arvanitakis C Giardiasis: clinical spectrum and functional-structural abnormalities of the small intestinal mucosa. Gastroenterology 1979, 77:61.
174. Oksenhendler E, Gerard L, Fieschi C, et al. Infections in 252 patients with common variable immunodeficiency. Clin Infect Dis 2008, 46:1547.
175. Bayry J, Lacroix-Desmazes S, Kazatchkine MD, et al. Common variable immunodeficiency is associated with defective functions of dendritic cells. Blood 2004, 104:2441.
176. LoGalbo PR, Sampson HA, Buckley RH Symptomatic giardiasis in three patients with X-linked agammaglobulinemia. J Pediatr 1982, 101:78.
177. Nash TE, Ohl CA, Thomas E, et al. Treatment of patients with refractory giardiasis. Clin Infect Dis 2001, 33:22.
178. Jokipii AMM, Jokipii L Prepatency of giardiasis. Lancet 1977, 1:1095.
179. Clyne CA, Eliopoulos GM Fever and urticaria in acute giardiasis. Arch Intern Med 1989, 149:939.
180. Giacometti A, Cirioni O, Antonicelli L, et al. Prevalence of intestinal parasites among individuals with allergic skin diseases. J Parasitol 2003, 89:490.
181. Fenollar F, Lepidi H, Gerolami R, et al. Whipple disease associated with giardiasis. J Infect Dis 2003, 188:828.
182. Shaw RA, Stevens MB The reactive arthritis of giardiasis. JAMA 1987, 258:2734.
183. Berney DM, Rampton D, van der Walt JD Giardiasis of the stomach. Postgrad Med J 1994, 70:237.
184. Hanevik K, Hausken T, Morken MH, et al. Persisting symptoms and duodenal inflammation related to Giardia duodenalis infection. J Infect 2007, 55:524.
185. Lengerich EJ, Addiss DG, Juranek DD Severe giardiasis in the United States. Clin Infect Dis 1994, 18:760.
186. Robertson LJ Severe giardiasis and cryptosporidiosis in Scotland, UK. Epidemiol Infect 1996, 117:551.
187. Mata LJ The Children of Santa María Cauqué: A Prospective Field Study of Health and Growth 1978, MIT Press, Cambridge, MA.
188. Rana SV, Bhasin DK, Vinayak VK Lactose hydrogen breath test in Giardia lamblia-positive patients. Dig Dis Sci 2005, 50:259.
189. Morch K, Hanevik K, Rortveit G, et al. High rate of fatigue and abdominal symptoms 2 years after an outbreak of giardiasis. Trans R Soc Trop Med Hyg 2009, 103:530.
190. Pickering LK, Woodward WE, DuPont HL, et al. Occurrence of Giardia lamblia in children in day care centers. J Pediatr 1984, 104:522.
191. Moya-Camarena SY, Sotelo N, Valencia ME Effects of asymptomatic Giardia intestinalis infection on carbohydrate absorption in well-nourished Mexican children. Am J Trop Med Hyg 2002, 66:255.
192. Sullivan PB, Marsh MN, Phillips MB, et al. Prevalence and treatment of giardiasis in chronic diarrhoea and malnutrition. Arch Dis Child 1991, 66:304.
193. Sackey ME, Weigel MM, Armijos RX Predictors and nutritional consequences of intestinal parasitic infections in rural Ecuadorian children. J Trop Pediatr 2003, 49:17.
194. Simsek Z, Zeyrek FY, Kurcer MA Effect of Giardia infection on growth and psychomotor development of children aged 0-5 years. J Trop Pediatr 2004, 50:90.
195. Celiksoz A, Acioz M, Degerli S, et al. Effects of giardiasis on school success, weight and height indices of primary school children in Turkey. Pediatr Int 2005, 47:567.
196. Goto R, Panter-Brick C, Northrop-Clewes CA, et al. Poor intestinal permeability in mildly stunted Nepali children: associations with weaning practices and Giardia lamblia infection. Br J Nutr 2002, 88:141.
197. Mukhopadhyay C, Wilson G, Pradhan D, et al. Intestinal protozoal infestation profile in persistent diarrhea in children below age 5 years in western Nepal. Southeast Asian J Trop Med Public Health 2007, 38:13.
198. Newman RD, Moore SR, Lima AA, et al. A longitudinal study of Giardia lamblia infection in north-east Brazilian children. Trop Med Int Health 2001, 6:624.
199. Gilman RH, Miranda E, Marquis GS, et al. Rapid reinfection by Giardia lamblia after treatment in a hyperendemic Third World community. Lancet 1988, 1:343.
200. Sullivan PS, DuPont HL, Arafat RR, et al. Illness and reservoirs associated with Giardia lamblia infection in rural Egypt: the case against treatment in developing world environments of high endemicity. Am J Epidemiol 1988, 127:1272.
201. Mondal D, Petri WA, Sack RB, et al. Entamoeba histolytica-associated diarrheal illness is negatively associated with the growth of preschool children: evidence from a prospective study. Trans R Soc Trop Med Hyg 2006, 100:1032.
202. Okhuysen PC Traveler's diarrhea due to intestinal protozoa. Clin Infect Dis 2001, 33:110.
203. Pierce KK, Kirkpatrick BD Update on human infections caused by intestinal protozoa. Curr Opin Gastroenterol 2009, 25:12.
204. Aldeen WE, Carroll K, Robison A, et al. Comparison of nine commercially available enzyme-linked immunosorbent assays for the detection of Giardia lamblia in fecal specimens. J Clin Microbiol 1998, 36:1338.
205. Garcia LS, Shimizu RY Evaluation of nine immunoassay kits (enzyme immunoassay and direct fluorescence) for detection of Giardia lamblia and Cryptosporidium parvum in human fecal specimens. J Clin Microbiol 1997, 35:1526.
206. Hiatt RA, Markell EK, Ng E How many stool examinations are necessary to detect pathogenic intestinal protozoa?. Am J Trop Med Hyg 1995, 53:36.
207. Church D, Miller K, Lichtenfeld A, et al. Screening for Giardia/ Cryptosporidium infections using an enzyme immunoassay in a centralized regional microbiology laboratory. Arch Pathol Lab Med 2005, 129:754.
208. Boone JH, Wilkins TD, Nash TE, et al. TechLab and Alexon Giardia enzyme-linked immunosorbent assay kits detect cyst wall protein 1. J Clin Microbiol 1999, 37:611.
209. Srijan A, Wongstitwilairoong B, Pitarangsi C, et al. Re-evaluation of commercially available enzyme-linked immunosorbent assay for the detection of Giardia lamblia and Cryptosporidium spp. from stool specimens. Southeast Asian J Trop Med Public Health 2005, 36(Suppl 4):26.
210. Johnston SP, Ballard MM, Beach MJ, et al. Evaluation of three commercial assays for detection of Giardia and Cryptosporidium organisms in fecal specimens. J Clin Microbiol 2003, 41:623.
211. Garcia LS, Garcia JP Detection of Giardia lamblia antigens in human fecal specimens by a solid-phase qualitative immunochromatographic assay. J Clin Microbiol 2006, 44:4587.
212. Garcia LS, Shimizu RY, Novak S, et al. Commercial assay for detection of Giardia lamblia and Cryptosporidium parvum antigens in human fecal specimens by rapid solid-phase qualitative immunochromatography. J Clin Microbiol 2003, 41:209.
213. Strand EA, Robertson LJ, Hanevik K, et al. Sensitivity of a Giardia antigen test in persistent giardiasis following an extensive outbreak. Clin Microbiol Infect 2008, 14:1069.
214. Guy RA, Payment P, Krull UJ, et al. Real-time PCR for quantification of Giardia and Cryptosporidium in environmental water samples and sewage. Appl Environ Microbiol 2003, 69:5178.
215. Guy RA, Xiao C, Horgen PA Real-time PCR assay for detection and genotype differentiation of Giardia lamblia in stool specimens. J Clin Microbiol 2004, 42:3317.
216. Haque R, Roy S, Siddique A, et al. Multiplex real-time PCR assay for detection of Entamoeba histolytica, Giardia intestinalis, and Cryptosporidium spp. Am J Trop Med Hyg 2007, 76:713.
217. Grazioli B, Matera G, Laratta C, et al. Giardia lamblia infection in patients with irritable bowel syndrome and dyspepsia: a prospective study. World J Gastroenterol 2006, 12:1941.
218. Wahnschaffe U, Ignatius R, Loddenkemper C, et al. Diagnostic value of endoscopy for the diagnosis of giardiasis and other intestinal diseases in patients with persistent diarrhea from tropical or subtropical areas. Scand J Gastroenterol 2007, 42:391.
219. Rosenthal P, Liebman WM Comparative study of stool examinations, duodenal aspiration, and pediatric Entero-Test for giardiasis in children. J Pediatr 1980, 96:278.
220. Goka AKJ, Rolston DDK, Mathan VI, et al. The relative merits of faecal and duodenal juice microscopy in the diagnosis of giardiasis. Trans R Soc Trop Med Hyg 1990, 84:66.
221. Crump JA, Mendoza CE, Priest JW, et al. Comparing serologic response against enteric pathogens with reported diarrhea to assess the impact of improved household drinking water quality. Am J Trop Med Hyg 2007, 77:136.
222. Cedillo-Rivera R, Leal YA, Yepez-Mulia L, et al. Seroepidemiology of giardiasis in Mexico. Am J Trop Med Hyg 2009, 80:6.
223. Isaac-Renton JL, Shahriari H, Bowie WR Comparison of an in vitro method and an in vivo method of Giardia excystation. Appl Environ Microbiol 1992, 58:1530.
224. Mayrhofer G, Andrews RH, Ey PL, et al. The use of suckling mice to isolate and grow Giardia from mammalian faecal specimens for genetic analysis. Parasitology 1992, 105:255.
225. Gardner TB, Hill DR Treatment of giardiasis. Clin Micro Rev 2001, 14:114.
226. Medical Letter Drugs for parasitic infections. Med Lett Drugs Ther 2007, 5(Suppl):1.
227. Medical Letter Nitazoxanide (Alinia) - a new anti-protozoal agent. Med Lett Drugs Ther 2003, 45:29.
228. Medical Letter Tinidazole (Tindamax) - a new anti-protozoal drug. Med Lett Drugs Ther 2004, 46:70.
229. Speelman P Single-dose tinidazole for the treatment of giardiasis. Antimicrob Agents Chemother 1985, 27:227.
230. Zaat JO, Mank T, Assendelft WJ. Drugs for treating giardiasis. Cochrane Database Syst Rev. 2000;CD000217.
231. Jokipii L, Jokipii AMM Single-dose metronidazole and tinidazole as therapy for giardiasis: success rates, side effects, and drug absorption and elimination. J Infect Dis 1979, 140:984.
232. Beard CM, Noller KL, O'Fallon WM Cancer after exposure to metronidazole. Mayo Clin Proc 1988, 63:147.
233. Falagas ME, Walker AM, Jick H, et al. Late incidence of cancer after metronidazole use: a matched metronidazole user/nonuser study. Clin Infect Dis 1998, 26:384.
234. Ozbilgin A, Ertan P, Yereli K, et al. Giardiasis treatment in Turkish children with a single dose of ornidazole. Scand J Infect Dis 2002, 34:918.
235. Jimenez JC, Pinon A, Dive D, et al. Antibody response in children infected with Giardia intestinalis before and after treatment with secnidazole. Am J Trop Med Hyg 2009, 80:11.
236. Anderson VR, Curran MP Nitazoxanide: a review of its use in the treatment of gastrointestinal infections. Drugs 2007, 67:1947.
237. Bailey JM, Erramouspe J Nitazoxanide treatment for giardiasis and cryptosporidiosis in children. Ann Pharmacother 2004, 38:634.
238. Escobedo AA, Alvarez G, Gonzalez ME, et al. The treatment of giardiasis in children: single-dose tinidazole compared with 3 days of nitazoxanide. Ann Trop Med Parasitol 2008, 102:199.
239. Canete R, Escobedo AA, Gonzalez ME, et al. Randomized clinical study of five days' therapy with mebendazole compared to quinacrine in the treatment of symptomatic giardiasis in children. World J Gastroenterol 2006, 12:6366.
240. Hall A, Nahar Q Albendazole as a treatment for infections with Giardia duodenalis in children in Bangladesh. Trans R Soc Trop Med Hyg 1993, 87:84.
241. Misra PK, Kumar A, Agarwal V, et al. A comparative trial of albendazole versus metronidazole in children with giardiasis. Indian Pediatr 1995, 32:779.
242. Yereli K, Balcioglu IC, Ertan P, et al. Albendazole as an alternative therapeutic agent for childhood giardiasis in Turkey. Clin Microbiol Infect 2004, 10:527.
243. Alizadeh A, Ranjbar M, Kashani KM, et al. Albendazole versus metronidazole in the treatment of patients with giardiasis in the Islamic Republic of Iran. East Mediterr Health J 2006, 12:548.
244. Kollaritsch H, Jeschko E, Wiederman G Albendazole is highly effective against cutaneous larva migrans but not against Giardia infection: results of an open pilot trial in travellers returning from the tropics. Trans R Soc Trop Med Hyg 1993, 87:689.
245. Diaz E, Mondragon J, Ramirez E, et al. Epidemiology and control of intestinal parasites with nitazoxanide in children in Mexico. Am J Trop Med Hyg 2003, 68:384.
246. Murphy TV, Nelson JD Five vs. ten days' therapy with furazolidone for giardiasis. Am J Dis Child 1983, 137:267.
247. Craft JC, Murphy T, Nelson JD Furazolidone and quinacrine. Comparative study of therapy for giardiasis in children. Am J Dis Child 1981, 135:164.
248. Andrews BJ, Panitescu D, Jipa GH, et al. Chemotherapy for giardiasis: randomized clinical trial of bacitracin, bacitracin zinc, and a combination of bacitracin zinc with neomycin. Am J Trop Med Hyg 1995, 52:318.
249. Burtin P, Taddio A, Ariburnu O, et al. Safety of metronidazole in pregnancy: a meta-analysis. Am J Obstet Gynecol 1995, 172:525.
250. Rosa FW, Baum C, Shaw M Pregnancy outcomes after first-trimester vaginitis drug therapy. Obstet Gynecol 1987, 69:751.
251. Tindamax (tinidazole) tablets for oral use. Prescribing Information 2007, Mission Pharmaceutical Company, San Antonio, TX.
252. Kreutner AK, Del Bene VE, Amstey MS Giardiasis in pregnancy. Am J Obstet Gynecol 1981, 140:895.
253. Rotblatt MD Giardiasis and amebiasis in pregnancy. Drug Intell Clin Pharm 1983, 17:187.
254. Upcroft P, Upcroft JA Drug targets and mechanisms of resistance in the anaerobic protozoa. Clin Micro Rev 2001, 14:150.
255. Paget TA, Jarroll EL, Manning P, et al. Respiration in the cysts and trophozoites of Giardia muris. J Gen Microbiol 1989, 135:145.
256. Townson SM, Upcroft JA, Upcroft P Characterization and purification of pyruvate:ferredoxin oxidoreductase from Giardia duodenalis. Mol Biochem Parasitol 1996, 79:183.
257. Samuelson J Why metronidazole is active against both bacteria and parasites. Antimicrob Agents Chemother 1999, 43:1533.
258. Taylor GD, Wenman WM, Tyrrell DLJ Combined metronidazole and quinacrine hydrochloride therapy for chronic giardiasis. Can Med Assoc J 1987, 136:1179.
259. Sawatzki M, Peter S, Hess C Therapy-resistant diarrhea due to Giardia lamblia in a patient with common variable immunodeficiency disease. Digestion 2007, 75:101.
260. Morch K, Hanevik K, Robertson LJ, et al. Treatment-ladder and genetic characterisation of parasites in refractory giardiasis after an outbreak in Norway. J Infect 2008, 56:268.
261. Abboud P, Lemee V, Gargala G, et al. Successful treatment of metronidazole- and albendazole-resistant giardiasis with nitazoxanide in a patient with acquired immunodeficiency syndrome. Clin Infect Dis 2001, 32:1792.
262. D'Anchino M, Orlando D, De Feudis L Giardia lamblia infections become clinically evident by eliciting symptoms of irritable bowel syndrome. J Infect 2002, 45:169.
263. Hanevik K, Dizdar V, Langeland N, et al. Development of functional gastrointestinal disorders after Giardia lamblia infection. BMC Gastroenterol 2009, 9:27.
264. Addiss DG, Juranek DD, Spencer HC Treatment of children with asymptomatic and nondiarrheal Giardia infection. Pediatr Infect Dis J 1991, 10:843.
265. Goto R, Mascie-Taylor CG, Lunn PG Impact of anti- Giardia and anthelminthic treatment on infant growth and intestinal permeability in rural Bangladesh: a randomised double-blind controlled study. Trans R Soc Trop Med Hyg 2009, 103:520.
266. Gupta MC, Urrutia JJ Effect of periodic antiascaris and anti- Giardia treatment on nutritional status of preschool children. Am J Clin Nutr 1982, 36:79.
267. Long KZ, Rosado JL, Montoya Y, et al. Effect of vitamin A and zinc supplementation on gastrointestinal parasitic infections among Mexican children. Pediatrics 2007, 120:e846.
268. Long KZ, Santos JI, Rosado JL, et al. Impact of vitamin A on selected gastrointestinal pathogen infections and associated diarrheal episodes among children in Mexico City, Mexico. J Infect Dis 2006, 194:1217.
269. Ochoa TJ, Cleary TG Effect of lactoferrin on enteric pathogens. Biochimie 2009, 91:30.
270. Jakubowski WS Purple burps and the filtration of drinking water supplies. Am J Public Health 1988, 78:123.
271. McGuigan KG, Mendez-Hermida F, Castro-Hermida JA, et al. Batch solar disinfection inactivates oocysts of Cryptosporidium parvum and cysts of Giardia muris in drinking water. J Appl Microbiol 2006, 101:453.
272. Backer HD Water disinfection for international travelers. Travel Medicine 2008, 47. Elsevier, Philadelphia. 2nd edn. J.S. Keystone, P.E. Kozarsky, D.O. Freedman (Eds.).
273. Ongerth JE, Johnson RL, MacDonald SC, et al. Backcountry water treatment to prevent giardiasis. Am J Public Health 1989, 79:1633.
274. Juranek DD Cryptosporidiosis: sources of infection and guidelines for prevention. Clin Infect Dis 1995, 21(suppl 1):S57.
275. Roach PD, Olson ME, Whitely G, et al. Waterborne Giardia cysts and Cryptosporidium oocysts in the Yukon, Canada. Appl Environ Microbiol 1993, 59:67.
276. Yoder JS, Beach MJ Cryptosporidiosis surveillance - United States, 2003-2005. MMWR Surveill Summ 2007, 56:1.
277. Ish-Horowicz M, Korman SH, Shapiro M, et al. Asymptomatic giardiasis in children. Pediatr Infect Dis J 1989, 8:773.
278. Nunez FA, Hernandez M, Finlay CM Longitudinal study of giardiasis in three day care centres of Havana City. Acta Trop 1999, 73:237.
279. Bartlett AV, Englender SJ, Jarvis BA, et al. Controlled trial of Giardia lamblia: control strategies in day care centers. Am J Public Health 1991, 81:1001.
280. Morrow AL, Reves RR, West MS, et al. Protection against infection with Giardia lamblia by breast feeding in a cohort of Mexican infants. J Pediatr 1992, 121:363.
281. Mahmud MA, Chappell CL, Hossain MM, et al. Impact of breast-feeding on Giardia lamblia infections in Bilbeis, Egypt. Am J Trop Med Hyg 2001, 65:257.
282. Bilenko N, Ghosh R, Levy A, et al. Partial breastfeeding protects Bedouin infants from infection and morbidity: prospective cohort study. Asia Pac J Clin Nutr 2008, 17:243.
283. Weiss LM, Keohane EM The uncommon gastrointestinal protozoa: microsporidia, blastocystis, isospora, dientamoeba, and balantidium. Curr Clin Top Infect Dis 1997, 17:147.
284. Schuster FL, Ramirez-Avila L Current world status of Balantidium coli. Clin Microbiol Rev 2008, 21:626.
285. Hindsbo O, Nielsen CV, Andreassen J, et al. Age-dependent occurrence of the intestinal ciliate Balantidium coli in pigs at a Danish research farm. Acta Vet Scand 2000, 41:79.
286. Weng YB, Hu YJ, Li Y, et al. Survey of intestinal parasites in pigs from intensive farms in Guangdong Province, People's Republic of China. Vet Parasitol 2005, 127:333.
287. Yatswako S, Faleke OO, Gulumbe ML, et al. Cryptosporidium oocysts and Balantidium coli cysts in pigs reared semi-intensively in Zuru, Nigeria. Pak J Biol Sci 2007, 10:3435.
288. Radford AJ Balantidiasis in Papua New Guinea. Med J Aust 1973, 1:238.
289. Devera R, Requena I, Velasquez V, et al. Balantidiasis in a rural community from Bolivar State, Venezuela. Bol Chil Parasitol 1999, 54:7.
290. Walzer PD, Judson FN, Murphy KB, et al. Balantidiasis outbreak in Truk. Am J Trop Med Hyg 1973, 22:33.
291. McCarey AG Balantidiasis in south Persia. BMJ 1952, 1:629.
292. Cox FE Human balantidiasis in Iran: are camels reservoir hosts?. Trends Parasitol 2005, 21:553.
293. Solaymani-Mohammadi S, Rezaian M, Anwar MA Human balantidiasis in Iran: an unresolved enigma?. Trends Parasitol 2005, 21:160.
294. Lee RV, Prowten AW, Anthone S, et al. Typhlitis due to Balantidium coli in captive lowland gorillas. Rev Infect Dis 1990, 12:1052.
295. Muriuki SM, Murugu RK, Munene E, et al. Some gastro-intestinal parasites of zoonotic (public health) importance commonly observed in old world non-human primates in Kenya. Acta Trop 1998, 71:73.
296. Lankester F, Matz-Rensing K, Kiyang J, et al. Fatal ulcerative colitis in a western lowland gorilla (Gorilla gorilla gorilla). J Med Primatol 2008, 37:297.
297. Areán VM, Koppisch E Balantidiasis. A review and report of cases. Am J Pathol 1956, 32:1089.
298. Esteban JG, Aguirre C, Angles R, et al. Balantidiasis in Aymara children from the northern Bolivian Altiplano. Am J Trop Med Hyg 1998, 59:922.
299. Swartzwelder JC Balantidiasis. Am J Digest Dis 1950, 17:173.
300. Dorfman S, Rangel O, Bravo LG Balantidiasis: report of a fatal case with appendicular and pulmonary involvement. Trans R Soc Trop Med Hyg 1984, 78:833.
301. Currie AR Human balantidiasis. A case report. S Afr J Surg 1990, 28:23.
302. Ferry T, Bouhour D, De Monbrison F, et al. Severe peritonitis due to Balantidium coli acquired in France. Eur J Clin Microbiol Infect Dis 2004, 23:393.
303. Cermeno JR, Hernandez De Cuesta I, Uzcategui O, et al. Balantidium coli in an HIV-infected patient with chronic diarrhoea (letter). AIDS 2003, 17:941.
304. Anargyrou K, Petrikkos GL, Suller MT, et al. Pulmonary Balantidium coli infection in a leukemic patient. Am J Hematol 2003, 73:180.
305. Vasilakopoulou A, Dimarongona K, Samakovli A, et al. Balantidium coli pneumonia in an immunocompromised patient. Scand J Infect Dis 2003, 35:144.
306. Yazar S, Altuntas F, Sahin I, et al. Dysentery caused by Balantidium coli in a patient with non-Hodgkin's lymphoma from Turkey. World J Gastroenterol 2004, 10:458.
307. Yang Y, Zeng L, Li M, et al. Diarrhoea in piglets and monkeys experimentally infected with Balantidium coli isolated from human feces. J Trop Med Hyg 1995, 98:69.
308. Tempelis CH, Lysenko MG The production of hyaluronidase by Balantidium coli. Exp Parasitol 1957, 6:31.
309. Garcia-Laverde A, de Bonilla L Clinical trials with metronidazole in human balantidiasis. Am J Trop Med Hyg 1957, 24:781.
310. Ochoa TJ, White AC Nitazoxanide for treatment of intestinal parasites in children. Pediatr Infect Dis J 2005, 24:641.
311. Johnson EH, Windsor JJ, Clark CG Emerging from obscurity: biological, clinical, and diagnostic aspects of Dientamoeba fragilis. Clin Microbiol Rev 2004, 17:553.
312. Stark DJ, Beebe N, Marriott D, et al. Dientamoebiasis: clinical importance and recent advances. Trends Parasitol 2006, 22:92.
313. Jepps MW, Dobell C A new intestinal amoeba from man. Parasitology 1918, 10:352.
314. Dwyer DM Analysis of the antigenic relationships among Trichomonas, Histomonas, Dientamoeba, and Entamoeba. I. Quantitative fluorescent antibody methods. J Protozool 1972, 19:316.
315. Gerbod D, Edgcomb VP, Noel C, et al. Phylogenetic position of the trichomonad parasite of turkeys, Histomonas meleagridis (Smith) Tyzzer, inferred from small subunit rRNA sequence. J Eukaryot Microbiol 2001, 48:498.
316. Silberman JD, Clark CG, Sogin ML Dientamoeba fragilis shares a recent common evolutionary history with the trichomonads. Mol Biochem Parasitol 1996, 76:311.
317. Johnson JA, Clark CG Cryptic genetic diversity in Dientamoeba fragilis. J Clin Microbiol 2000, 38:4653.
318. Peek R, Reedeker FR, van Gool T Direct amplification and genotyping of Dientamoeba fragilis from human stool specimens. J Clin Microbiol 2004, 42:631.
319. Stark D, Beebe N, Marriott D, et al. Prospective study of the prevalence, genotyping, and clinical relevance of Dientamoeba fragilis infections in an Australian population. J Clin Microbiol 2005, 43:2718.
320. Vandenberg O, Peek R, Souayah H, et al. Clinical and microbiological features of dientamoebiasis in patients suspected of suffering from a parasitic gastrointestinal illness: a comparison of Dientamoeba fragilis and Giardia lamblia infections. Int J Infect Dis 2006, 10:255.
321. Bart A, van der Heijden HM, Greve S, et al. Intragenomic variation in the internal transcribed spacer 1 region of Dientamoeba fragilis as a molecular epidemiological marker. J Clin Microbiol 2008, 46:3270.
322. Yang J, Scholten T Dientamoeba fragilis: a review with notes on its epidemiology, pathogenicity, mode of transmission, and diagnosis. Am J Trop Med Hyg 1977, 26:16.
323. Schuster H, Jackson RS Prevalence of Dientamoeba fragilis among patients consulting complementary medicine practitioners in the British Isles. J Clin Pathol 2009, 62:182.
324. Ayadi A, Bahri I Dientamoeba fragilis: pathogenic flagellate?. Bull Soc Pathol Exot 1999, 92:299.
325. Windsor JJ, Rafay AM, Shenoy AK, et al. Incidence of Dientamoeba fragilis in faecal samples submitted for routine microbiological analysis. Br J Biomed Sci 1998, 55:172.
326. Grendon JH, Digiacomo RF, Frost FJ Dientamoeba fragilis detection methods and prevalence: a survey of state public health laboratories. Publ Health Rep 1991, 106:322.
327. Melvin DM, Brooke MM Parasitologic surveys on Indian reservations in Montana, South Dakota, New Mexico, Arizona, and Wisconsin. Am J Trop Med Hyg 1962, 11:765.
328. Millet VE, Spencer MJ, Chapin MR, et al. Intestinal protozoan infection in a semicommunal group. Am J Trop Med Hyg 1983, 32:54.
329. McQuay RM Parasitologic studies in a group of furloughed missionaries. I. Intestinal protozoa. Am J Trop Med Hyg 1967, 16:154.
330. Stark D, Beebe N, Marriott D, et al. Dientamoeba fragilis as a cause of travelers' diarrhea: report of seven cases. J Travel Med 2007, 14:72.
331. Oyofo BA, Peruski LF, Ismail TF, et al. Enteropathogens associated with diarrhea among military personnel during Operation Bright Star 96, in Alexandria, Egypt. Mil Med 1997, 162:396.
332. Preiss U, Ockert G, Bromme S, et al. Dientamoeba fragilis infection, a cause of gastrointestinal symptoms in childhood. Klin Paediatr 1990, 202:120.
333. Girginkardesler N, Kurt O, Kilimcioglu AA, et al. Transmission of Dientamoeba fragilis: evaluation of the role of Enterobius vermicularis. Parasitol Int 2008, 57:72.
334. Burrows RB, Swerdlow MA Enterobius vermicularis as a probable vector of Dientamoeba fragilis. Am J Trop Med Hyg 1956, 5:258.
335. Ockert G Zur Epidemiologie von Dientamoeba fragilis Jepps et Dobell, 1918. 2. Mitteilung: Versuch der Übertragung der Art mit Enterobiuseiern. J Hyg Epidemiol Microbiol Immunol 1972, 16:222.
336. Spencer MJ, Chapin MR, Garcia LS Dientamoeba fragilis: a gastrointestinal protozoan infection in adults. Am J Gastroenterol 1982, 77:565.
337. Spencer MJ, Garcia LS, Chapin MR Dientamoeba fragilis. An intestinal pathogen in children?. Am J Dis Child 1979, 133:390.
338. Grendon JH, DiGiacomo RF, Frost FJ Descriptive features of Dientamoeba fragilis infections. J Trop Med Hyg 1995, 98:309.
339. Norberg A, Nord CE, Evengard B Dientamoeba fragilis - a protozoal infection which may cause severe bowel distress. Clin Microbiol Infect 2003, 9:65.
340. Ito R, Sakagami J, Kataoka K, et al. Chronic diarrhea and protein-losing gastroenteropathy caused by Dientamoeba fragilis. J Gastroenterol 2004, 39:1117.
341. Borody TJ, Warren EF, Wettstein A, et al. Eradication of Dientamoeba fragilis can resolve IBS-like symptoms. J Gastroenterol Hepatol 2002, 17(suppl):A103.
342. Windsor JJ, Macfarlane L Irritable bowel syndrome: the need to exclude Dientamoeba fragilis. Am J Trop Med Hyg 2005, 72:501.
343. Schwartz MD, Nelson ME Dientamoeba fragilis infection presenting to the emergency department as acute appendicitis. J Emerg Med 2003, 25:17.
344. Talis B, Stein B, Lengy J Dientamoeba fragilis in human feces and bile. Isr J Med Sci 1971, 7:1063.
345. Shein R, Gelb A Colitis due to Dientamoeba fragilis. Am J Gastroenterol 1983, 78:634.
346. Sawangjaroen N, Luke R, Prociv P Diagnosis by faecal culture of Dientamoeba fragilis infections in Australian patients with diarrhea. Trans R Soc Trop Med Hyg 1993, 87:163.
347. Windsor JJ, Macfarlane L, Hughes-Thapa G, et al. Detection of Dientamoeba fragilis by culture. Br J Biomed Sci 2003, 60:79.
348. Chan F, Stewart N, Guan M, et al. Prevalence of Dientamoeba fragilis antibodies in children and recognition of a 39 kDa immunodominant protein antigen of the organism. Eur J Clin Microbiol Infect Dis 1996, 15:950.
349. Stark D, Beebe N, Marriott D, et al. Evaluation of three diagnostic methods, including real-time PCR, for detection of Dientamoeba fragilis in stool specimens. J Clin Microbiol 2006, 44:232.
350. Cuffari C, Oligny L, Seidman EG Dientamoeba fragilis masquerading as allergic colitis. J Pediatr Gastroenterol Nutr 1998, 26:16.
351. Girginkardesler N, Coskun S, Cuneyt Balcioglu I, et al. Dientamoeba fragilis, a neglected cause of diarrhea, successfully treated with secnidazole. Clin Microbiol Infect 2003, 9:110.
352. Vandenberg O, Souayah H, Mouchet F, et al. Treatment of Dientamoeba fragilis infection with paromomycin. Pediatr Infect Dis J 2007, 26:88.
353. Kurt O, Girginkardesler N, Balcioglu IC, et al. A comparison of metronidazole and single-dose ornidazole for the treatment of dientamoebiasis. Clin Microbiol Infect 2008, 14:601.
354. The flagellates. Medical Parasitology 1986, 54. WB Saunders, Philadelphia. 6th edn. E.K. Markell, M. Voge, D.T. John (Eds.).
355. Wolfe MS Miscellaneous intestinal protozoa. Hunter's Tropical Medicine and Emerging Infectious Diseases 2000, 603. WB Saunders, Philadelphia. 8th edn. G.T. Strickland (Ed.).
356. Abd-Alla MD, Wahib AA, Ravdin JI Comparison of antigen-capture ELISA to stool-culture methods for the detection of asymptomatic Entamoeba species infection in Kafer Daoud, Egypt. Am J Trop Med Hyg 2000, 62:579.
357. Spriegel JR, Saag KG, Tsang T-K Infectious diarrhea secondary to Enteromonas hominis. Am J Gastroenterol 1989, 84:1313.
358. Singh S, Samantaray JC So-called nonpathogenic intestinal parasites (letter). Am J Gastroenterol 1990, 85:764.
359. Crucitti T, Abdellati S, Ross DA, et al. Detection of Pentatrichomonas hominis DNA in biological specimens by PCR. Lett Appl Microbiol 2004, 38:510.
360. Jongwutiwes S, Silachamroon U, Putaporntip C Pentatrichomonas hominis in empyema thoracis. Trans R Soc Trop Med Hyg 2000, 94:185.
361. Kawamura O, Kon Y, Naganuma A, et al. Retortamonas intestinalis in the pancreatic juice of a patient with small nodular lesions of the main pancreatic duct. Gastrointest Endosc 2001, 53:508.
362. Honingberg BM Trichomonads found outside the urogenital tract of humans. Trichomonads Parasitic in Humans 1990, Springer-Verlag, New York. B.M. Honingberg (Ed.).