The O2-scavenging flavodiiron protein in the human parasite Giardia intestinalis

Journal of Biological Chemistry

Volumn 283, Issue 7, 2008, Pages 4061-4068

  Di Matteo, Adele ^a   Scandurra, Francesca Maria ^a   Testa, Fabrizio ^a   Forte, Elena ^a   Sarti, Paolo ^a   Brunori, Maurizio ^a   Giuffrè, Alessandro ^a,b  

^a CNR   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTALLOGRAPHY; ENZYME ACTIVITY; ENZYMES; ESCHERICHIA COLI; IRON ANALYSIS; MONOMERS; OLIGOMERS; PORPHYRINS; THREE DIMENSIONAL;

AMPEROMETRY; CAUSATIVE AGENTS; DESULFOVIBRIO; DIMENSIONAL STRUCTURES; GIARDIA; GIARDIA INTESTINALIS; HIGH AFFINITIES; HPLC ANALYSES; HUMAN PARASITES; INFECTIOUS DISEASES; MICROAEROBIC; PRIMARY FUNCTIONS; REDUCTASE ACTIVITIES; RESPIROMETRY; SMALL INTESTINES; X-RAY CRYSTALLOGRAPHIES;

X RAY CRYSTALLOGRAPHY;

BACTERIAL PROTEIN; FLAVOPROTEIN; FRUCTOSE BISPHOSPHATE; HYDROGEN PEROXIDE; NITRIC OXIDE REDUCTASE; OXYGEN; PROTEIN FLAVODIIRON; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; UNCLASSIFIED DRUG; IRON;

AMPEROMETRY; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DESULFOVIBRIO GIGAS; ESCHERICHIA COLI; GIARDIA; GIARGIA INTESTINALIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KINETICS; NONHUMAN; OXIDATION; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN STRUCTURE; RESPIROMETRY; SPECTROSCOPY; X RAY CRYSTALLOGRAPHY; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; GIARDIA LAMBLIA; METABOLISM; PROTEIN CONFORMATION;

DESULFOVIBRIO GIGAS; ESCHERICHIA COLI; GIARDIA; GIARDIA INTESTINALIS; PROKARYOTA; PROTOZOA;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRYSTALLOGRAPHY, X-RAY; FLAVOPROTEINS; GIARDIA LAMBLIA; IRON; MODELS, MOLECULAR; OXYGEN; PROTEIN CONFORMATION; SPECTRUM ANALYSIS;

EID: 42949120247     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M705605200     Document Type: Article

References (47)

1. Wasserfallen, A., Ragettli, S., Jouanneau, Y., and Leisinger, T. (1998) Eur. J. Biochem. 254, 325-332
2. Gardner, A. M., Helmick, R. A., and Gardner, P. R. (2002) J. Biol. Chem. 277, 8172-8177
3. Saraiva, L. M., Vicente, J. B., and Teixeira, M. (2004) Adv. Microb. Physiol. 49, 77-129
4. Chen, L., Liu, M. Y., LeGall, J., Fareleira, P., Santos, H., and Xavier, A. V. (1993) Biochem. Biophys. Res. Commun. 193, 100-105
5. Gomes, C. M., Silva, G., Oliveira, S., LeGall, J., Liu, M. Y., Xavier, A. V., Rodrigues-Pousada, C., and Teixeira, M. (1997) J. Biol. Chem. 272, 22502-22508
6. Frazao, C., Silva, G., Gomes, C. M., Matias, P., Coelho, R., Sieker, L., Macedo, S., Liu, M. Y., Oliveira, S., Teixeira, M., Xavier, A. V., Rodrigues-Pousada, C., Carrondo, M. A., and Le Gall, J. (2000) Nat. Struct. Biol. 7, 1041-1045
7. Rodrigues, R., Vicente, J. B., Felix, R., Oliveira, S., Teixeira, M., and Rodrigues-Pousada, C. (2006) J. Bacteriol. 188, 2745-2751
8. Gomes, C. M., Vicente, J. B., Wasserfallen, A., and Teixeira, M. (2000) Biochemistry 39, 16230-16237
9. Gomes, C. M., Giuffre, A., Forte, E., Vicente, J. B., Saraiva, L. M., Brunori, M., and Teixeira, M. (2002) J. Biol. Chem. 277, 25273-25276
10. Vicente, J. B., and Teixeira, M. (2005) J. Biol. Chem. 280, 34599-34608
11. Vicente, J. B., Scandurra, F. M., Rodrigues, J. V., Brunori, M., Sarti, P., Teixeira, M., and Giuffre, A. (2007) Febs J. 274, 677-686
12. Silaghi-Dumitrescu, R., Ng, K. Y., Viswanathan, R., and Kurtz, D. M., Jr. (2005) Biochemistry 44, 3572-3579
13. Silaghi-Dumitrescu, R., Coulter, E. D., Das, A., Ljungdahl, L. G., Jameson, G. N., Huynh, B. H., and Kurtz, D. M., Jr. (2003) Biochemistry 42, 2806-2815
14. Silaghi-Dumitrescu, R., Kurtz, D. M., Jr., Ljungdahl, L. G., and Lanzilotta, W. N. (2005) Biochemistry 44, 6492-6501
15. Seedorf, H., Dreisbach, A., Hedderich, R., Shima, S., and Thauer, R. K. (2004) Arch. Microbiol. 182, 126-137
16. Seedorf, H., Hagemeie, C. H., Shima, S., Thauer, R. K., Warkentin, E., and Ermler, U. (2007) Febs J. 274, 1588-1599
17. Fang, F. C. (1997) J. Clin. Investig. 99, 2818-2825
18. MacMicking, J., Xie, Q. W., and Nathan, C. (1997) Annu. Rev. Immunol. 15, 323-350
19. Andersson, J. O., Sjogren, A. M., Davis, L. A., Embley, T. M., and Roger, A. J. (2003) Curr. Biol. 13, 94-104
20. Loftus, B., Anderson, I., Davies, R., Alsmark, U. C., Samuelson, J., Amedeo, P., Roncaglia, P., Berriman, M., Hirt, R. P., Mann, B. J., Nozaki, T., Suh, B., Pop, M., Duchene, M., Ackers, J., Tannich, E., Leippe, M., Hofer, M., Bruchhaus, I., Willhoeft, U., Bhattacharya, A., Chillingworth, T., Churcher, C., Hance, Z., Harris, B., Harris, D., Jagels, K., Moule, S., Mungall, K., Ormond, D., Squares, R., Whitehead, S., Quail, M. A., Rabbinowitsch, E., Norbertczak, H., Price, C., Wang, Z., Guillen, N., Gilchrist, C., Stroup, S. E., Bhattacharya, S., Lohia, A., Foster, P. G., Sicheritz-Ponten, T., Weber, C., Singh, U., Mukherjee, C., El-Sayed, N. M., Petri, W. A., Jr., Clark, C. G., Embley, T. M., Barrell, B., Fraser, C. M., and Hall, N. (2005) Nature 433, 865-868
21. Andersson, J. O., Hirt, R. P., Foster, P. G., and Roger, A. J. (2006) BMC Evol. Biol. 6, 27
22. Sarti, P., Fiori, P. L., Forte, E., Rappelli, P., Teixeira, M., Mastronicola, D., Sanciu, G., Giuffre, A., and Brunori, M. (2004) Cell Mol. Life Sci. 61, 618-623
23. Roxstrom-Lindquist, K., Palm, D., Reiner, D., Ringqvist, E., and Svard, S. G. (2006) Trends Parasitol. 22, 26-31
24. Morrison, H. G., McArthur, A. G., Gillin, F. D., Aley, S. B., Adam, R. D., Olsen, G. J., Best, A. A., Cande, W. Z., Chen, F., Cipriano, M. J., Davids, B. J., Dawson, S. C., Elmendorf, H. G., Hehl, A. B., Holder, M. E., Huse, S. M., Kim, U. U., Lasek-Nesselquist, E., Manning, G., Nigam, A., Nixon, J. E., Palm, D., Passamaneck, N. E., Prabhu, A., Reich, C. I., Reiner, D. S., Samuelson, J., Svard, S. G., and Sogin, M. L. (2007) Science 317, 1921-1926
25. Brown, D. M., Upcroft, J. A., Edwards, M. R., and Upcroft, P. (1998) Int. J. Parasitol. 28, 149-164
26. Brown, D. M., Upcroft, J. A., and Upcroft, P. (1995) Mol. Biochem. Parasitol. 72, 47-56
27. Brown, D. M., Upcroft, J. A., and Upcroft, P. (1996) Eur. J. Biochem. 241, 155-161
28. Smith, P. K., Krohn, R. I., Hermanson, G. T., Mallia, A. K., Gartner, F. H., Provenzano, M. D., Fujimoto, E. K., Goeke, N. M., Olson, B. J., and Klenk, D. C. (1985) Anal. Biochem. 150, 76-85
29. Susin, S., Abian, J., Sanchez-Baeza, F., Peleato, M. L., Abadia, A., Gelpi, E., and Abadia, J. (1993) J. Biol. Chem. 268, 20958-20965
30. Stookey, L. L. (1970) Anal. Chem. 42, 779-781
31. Otwinowski, Z., and Minor, W. (eds) (1997) Methods in Enzymology (Carter, C. W., and Sweet, R. M., eds) Academic Press, New York
32. Vagin, A., and Teplyakov, A. (1997) J. Appl. Crystallogr. 30, 1022-1025
33. Murshudov, G. N., Vagin, A. A., and Dodson, E. J. (1997) Acta Crystallogr. D Biol. Crystallogr. 53, 240-255
34. Emsley, P., and Cowtan, K. (2004) Acta Crystallogr. D Biol. Crystallogr. 60, 2126-2132
35. Laskowski, R. R., MacArthur, M. W., Moss, D. S., and Thornton, J. M. (1993) J. Appl. Crystallogr. 26, 283-291
36. Krissinel, E., and Henrick, K. (2004) Acta Crystallogr. D Biol. Crystallogr. 60, 2256-2268
37. Sobolev, V., Sorokine, A., Prilusky, J., Abola, E. E., and Edelman, M. (1999) Bioinformatics 15, 327-332
38. Lee, B., and Richards, F. M. (1971) J. Mol. Biol. 55, 379-400
39. Solomon, E. I., Brunold, T. C., Davis, M. I., Kemsley, J. N., Lee, S. K., Lehnert, N., Neese, F., Skulan, A. J., Yang, Y. S., and Zhou, J. (2000) Chem. Rev. 100, 235-350
40. Lloyd, D., Harris, J. C., Maroulis, S., Biagini, G. A., Wadley, R. B., Turner, M. P., and Edwards, M. R. (2000) Microbiology 146, 3109-3118
41. Townson, S. M., Upcroft, J. A., and Upcroft, P. (1996) Mol. Biochem. Parasitol. 79, 183-193
42. Li, L., and Wang, C. C. (2006) Mol. Microbiol. 59, 202-211
43. Sheridan, W. G., Lowndes, R. H., and Young, H. L. (1990) Am. J. Surg. 159, 314-319
44. Paget, T. A., Jarroll, E. L., Manning, P., Lindmark, D. G., and Lloyd, D. (1989) J. Gen. Microbiol. 135, 145-154
45. Ellis, J. E., Wingfield, J. M., Cole, D., Boreham, P. F., and Lloyd, D. (1993) Int. J. Parasitol. 23, 35-39
46. Eckmann, L., Laurent, F., Langford, T. D., Hetsko, M. L., Smith, J. R., Kagnoff, M. F., and Gillin, F. D. (2000) J. Immunol. 164, 1478-1487
47. Li, E., Zhou, P., and Singer, S. M. (2006) J. Immunol. 176, 516-521