Biological selection of variant-specific surface proteins in Giardia lamblia

Journal of Infectious Diseases

Volumn 183, Issue 1, 2001, Pages 119-124

  Singer, Steven M ^a,b   Elmendorf, Heidi G ^a,b   Conrad, John T ^a   Nash, Theodore E ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b GEORGETOWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE PROTEIN;

ADAPTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ANTIGENIC VARIATION; ARTICLE; CONTROLLED STUDY; FEMALE; GENETIC SELECTION; GIARDIA LAMBLIA; HOST PARASITE INTERACTION; IMMUNE DEFICIENCY; IMMUNE RESPONSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTOZOAL INFECTION;

ANIMALS; ANTIGENIC VARIATION; ANTIGENS, PROTOZOAN; ANTIGENS, SURFACE; FEMALE; GERBILLINAE; GIARDIA LAMBLIA; GIARDIASIS; HOST-PARASITE RELATIONS; IMMUNOCOMPETENCE; IMMUNOSUPPRESSION; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, SCID;

EID: 0035174430     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/317659     Document Type: Article

References (41)

1. Shared themes of antigenic variation and virulence in bacterial, protozoal, and fungal infections
2. Adherence of infected erythrocytes to venular endothelium selects for antigenic variants of Plasmodium falciparum
3. Molecular basis of surface antigen variation in paramecia
4. Antigenic variation in Giardia lamblia and the host's immune response
5. Characterization of a Giardia lamblia variant-specific surface protein (VSP) gene from isolate GS/M and estimation of the VSP gene repertoire size
6. Sequence survey of the Giardia lamblia genome
7. Differences in excretory-secretory products and surface antigens among 19 isolates of Giardia
8. Isolation and expression of the gene for a major surface protein of Giardia lamblia
9. Variant surface antigens of Giardia lamblia are associated with the presence of a thick ceil coat: Thin section and label fracture immunocytochemistry survey
10. The enigma of LIM domains
11. RING domains: Master builders of molecular scaffolds?
12. Immune response to Giardia duodenalis
13. Antibody response to Giardia muris trophozoites in mouse intestine
14. Antigenic variation of Giardia lamblia in experimental human infections
15. Antigenic variation in Giardia lamblia
16. Antigenic variation in Giardia lamblia
17. Cysteine-rich variant surface proteins of Giardia lamblia
18. Giardia lamblia infections in B-cell-deficient transgenic mice
19. T-cell-dependent control of acute Giardia lamblia infections in mice
20. Antigenic variation in Giardia lamblia: Infection of congenitally athymic nude and scid mice
21. Axenic culture of Giardia lamblia in TYI-S-33 medium supplemented with bile
22. Purification of a variant-specific surface protein of Giardia lamblia and characterization of its metal-binding properties
23. Cytotoxicity of monoclonal antibodies to a subset of Giardia isolates
24. Binding and transepithelial transport of immunoglobulins by intestinal M cells: Demonstration using monoclonal IgA antibodies against enteric viral proteins
25. Separation of a cysteine-rich surface antigen-expressing variant from a cloned Giardia isolate by fluorescence-activated cell sorting
26. Giardia lamblia infections in adult mice
27. The hematological effects of irradiation on the Indian desert gerbil (Meriones hurrianae Jerdon)
28. The role of normal flora in Giardia lamblia infections in mice
29. Frequency of variant antigens in Giardia lamblia
30. Giardia lamblia infections in Mongolian gerbils: An animal model
31. Cell biology of the primitive eukaryote Giardia lamblia
32. Isolate and epitope variability in susceptibility of Giardia lamblia to intestinal proteases
33. Killing of Giardia lamblia by cryptdins and cationic neutrophil peptides
34. Comparison of two antigenically distinct Giardia lamblia isolates in gerbils
35. Isolation of two Giardia lamblia (WB strain) clones with distinct surface protein and antigenic profiles and differing infectivity and virulence
36. Selection of specific genotypes of Giardia intestinalis by growth in vitro and in vivo
37. Antigenic switching of TSA 417, a trophozoite variable surface protein, following completion of the life cycle of Giardia lamblia
38. Differentiationassociated surface antigen variation in the ancient eukaryote Giardia lamblia
39. Cross-species transmission of Giardia spp.: Inoculation of beavers and muskrats with cysts of human, beaver, mouse, and muskrat origin
40. Control of VSG gene expression sites in Trypanosoma brucei
41. The role of transferrin-receptor variation in the host range of Trypanosoma brucei