Polycystin-1 is required for stereocilia structure but not for mechanotransduction in inner ear hair cells

Journal of Neuroscience

Volumn 31, Issue 34, 2011, Pages 12241-12250

  Steigelman, Katherine A ^a,b   Lelli, Andrea ^c   Wu, Xudong ^a   Gao, Jiangang ^a   Lin, Susan ^a   Piontek, Klaus ^d   Wodarczyk, Claas ^e   Boletta, Alessandra ^e   Kim, Hyunho ^d   Qian, Feng ^d   Germino, Gregory ^d,f   Géléoc, Gwenälle S G ^c   Holt, Jeffrey R ^c   Zuo, Jian ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

^d JOHNS HOPKINS UNIVERSITY   (United States)

^e DULBECCO TELETHON INSTITUTE   (Italy)

^f NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

F ACTIN; POLYCYSTIN 1;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL POLARITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; FEMALE; HAIR CELL; HEARING LOSS; IN VITRO STUDY; IN VIVO STUDY; INNER EAR; KIDNEY EPITHELIUM; MALE; MECHANOTRANSDUCTION; MICROVILLUS; MOUSE; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; STEREOCILIUM;

ANIMALS; ANIMALS, NEWBORN; CILIA; DISEASE MODELS, ANIMAL; FEMALE; GENE KNOCK-IN TECHNIQUES; HAIR CELLS, AUDITORY, INNER; HEARING LOSS, SENSORINEURAL; HELA CELLS; HUMANS; MALE; MECHANOTRANSDUCTION, CELLULAR; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; ORGAN OF CORTI; TRPP CATION CHANNELS;

EID: 80052153568     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.6531-10.2011     Document Type: Article

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