Excess F-actin mechanically impedes mitosis leading to cytokinesis failure in X-linked neutropenia by exceeding Aurora B kinase error correction capacity

Blood

Volumn 120, Issue 18, 2012, Pages 3803-3811

  Moulding, Dale A ^a   Moeendarbary, Emad ^b   Valon, Leo ^b,c   Record, Julien ^a   Charras, Guillaume T ^b   Thrasher, Adrian J ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c ECOLE NORMALE SUPÉRIEURE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AURORA B KINASE; F ACTIN;

ARTICLE; CELL DIVISION; CENTROMERE; CHROMOSOME; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINESIS; CYTOPLASM; ENZYME ACTIVITY; ENZYME INHIBITION; GENOMIC INSTABILITY; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; MICROTUBULE; MITOSIS; NEUTROPENIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; VISCOSITY; X LINKED NEUTROPENIA;

EID: 84868604959     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-03-419663     Document Type: Article

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