Performance of in vitro γh2AX assay in HepG2 cells to predict in vivo genotoxicity

Mutagenesis

Volumn 27, Issue 6, 2012, Pages 645-652

  Tsamou, Maria ^a   Jennen, Danyel G J ^a   Claessen, Sandra M H ^a   Magkoufopoulou, Christina ^a   Kleinjans, Jos C S ^a   Van Delft, Joost H M ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA H2AX PROTEIN; HISTONE H2AX; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HEPG2; CHROMOSOME ABERRATION; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; GENOTOXICITY; HEPATOMA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LYMPHOMA; METABOLIC ACTIVATION; MICRONUCLEUS TEST; MUTAGEN TESTING; PREDICTION; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY;

CARCINOGENS; CHROMOSOME ABERRATIONS; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; HEP G2 CELLS; HISTONES; HUMANS; MUTAGENICITY TESTS; PHOSPHORYLATION; SENSITIVITY AND SPECIFICITY;

BACTERIA (MICROORGANISMS);

EID: 84868596529     PISSN: 02678357     EISSN: 14643804     Source Type: Journal    
DOI: 10.1093/mutage/ges030     Document Type: Article

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