Detection of DNA adducts using a quantitative long PCR technique and the fluorogenic 5′ nuclease assay (TaqMan®)

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 484, Issue 1-2, 2001, Pages 3-18

  Laws, George M ^a   Skopek, Thomas R ^a   Reddy, M Vijayaraj ^a   Storer, Richard D ^a   Glaab, Warren E ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

32P postlabeling; DNA adducts; Human globin gene; TaqMan ; XL PCR

Indexed keywords

3 INDOLEMETHANOL; 6 CHLORO 9 [3 (2 CHLOROETHYL)AMINOPROPYLAMINO] 2 METHOXYACRIDINE; ACETONE; AFLATOXIN B1; BENZO[A]PYRENE; BETA GLOBIN; BUTADIENE DIEPOXIDE; CHLOROFORM; CLOFIBRATE; DIETHYLNITROSAMINE; DIMETHYLBENZ[A]ANTHRACENE; DNA; ETHYLNITROSOUREA; FLUOROGENIC 5' NUCLEASE; HYDROGEN PEROXIDE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MESYLIC ACID METHYL ESTER; N (2 FLUORENYL)ACETAMIDE; NUCLEASE; PHENOBARBITAL; PHOSPHORUS 32; SKATOLE; STYRENE OXIDE; UNCLASSIFIED DRUG;

ACCURACY; ANALYTIC METHOD; ARTICLE; CONTROLLED STUDY; DEVICE; DNA ADDUCT; DNA DAMAGE; DNA DETERMINATION; DNA SEQUENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HUMAN GENETICS; INTERMETHOD COMPARISON; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE ASSAY; SEQUENCE ANALYSIS; THIN LAYER CHROMATOGRAPHY; VALIDATION PROCESS;

ANIMALS; BASE SEQUENCE; BIOTRANSFORMATION; CELL LINE; DNA ADDUCTS; DNA DAMAGE; DNA PRIMERS; DNA PROBES; FIBROBLASTS; FLUORESCENT DYES; GLOBINS; HUMANS; HYDROGEN PEROXIDE; LIVER; MUTAGENICITY TESTS; MUTAGENS; PHOSPHORUS RADIOISOTOPES; POLYMERASE CHAIN REACTION; RATS; TAQ POLYMERASE;

EID: 0035852068     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(01)00263-9     Document Type: Article

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