Suitable top concentration for tests with mammalian cells: Mouse lymphoma assay workgroup

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 723, Issue 2, 2011, Pages 84-86

  Moore, Martha M ^a   Honma, Masamitsu ^b   Clements, Julie ^c   Awogi, Takumi ^d   Douglas, George R ^e   Van Goethem, Freddy ^f   Gollapudi, Bhaskar ^g   Kimura, Aoi ^h   Muster, Wolfgang ⁱ   O'Donovan, Mike ^j   Schoeny, Rita ^k   Wakuri, Shinobu ^l  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^c UK   (United Kingdom)

^d OTSUKA PHARMACEUTICAL CO LTD   (Japan)

^e Environmental Health Center   (Canada)

^f JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^g DOW CHEMICAL COMPANY   (United States)

^h SHIN NIPPON BIOMEDICAL LABORATORIES LTD   (Japan)

ⁱ F HOFFMANN LA ROCHE LTD   (Switzerland)

^j ASTRAZENECA   (United Kingdom)

^k U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^l HATANO RESEARCH INSTITUTE   (Japan)

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Author keywords

Mouse lymphoma assay; Thymidine kinase mutation; Top concentration

Indexed keywords

CARCINOGEN TESTING; CARCINOGENIC ACTIVITY; CELL ASSAY; CELL CULTURE; COLONY FORMATION; CONCENTRATION (PARAMETERS); GENOTOXICITY; GOLD STANDARD; IN VIVO STUDY; MOUSE; MOUSE LYMPHOMA ASSAY; MUTAGEN TESTING; NONHUMAN; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT;

ANIMALS; LYMPHOMA; MICE; MUTAGENICITY TESTS; PROFESSIONAL AUTONOMY;

MAMMALIA;

EID: 79959741667     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2011.04.001     Document Type: Review

References (7)

1. Moore M.M., Honma M., Clements J., Awogi T., Bolcsfoldi G., Cole J., Gollapudi B., Harrington-Brock K., Mitchell A., Muster W., Myhr B., O'Donovan M., Ouldelhkim M.-C., San R., Shimada H., Stankowski L.F. The mouse lymphoma thymidine kinase locus (tk) gene mutation assay. Environ. Mol. Mutagen 2000, 35:185-190.
2. Moore M.M., Honma M., Clements J., Harrington-Brock K., Awogi T., Bolcsfoldi G., Cifone M., Collard D., Fellows M., Flanders K., Gollapudi B., Jenkinson P., Kirby P., Kirchner S., Kraycer J., McEnaney S., Muster W., Myhr B., O'Donovan M., Oliver J., Ouldelhkim M.-C., Pant K., Preston R., Riach C., San R., Shimada H., Stankowski L.F. Mouse lymphoma thymidine kinase locus gene mutation assay. Environ. Mol. Mutagen 2002, 40:292-299.
3. Moore M.M., Honma M., Clements J., Bolcsfoldi G., Cifone M., Delongchamp R., Fellows M., Gollapudi B., Jenkinson P., Kirby P., Kirchner S., Muster W., Myhr B., O'Donovan M., Ouldelhkim M.-C., Pant K., Preston R., Riach C., San R., Stankowski L.F., Thakur A., Wakuri S., Yoshimura I. Mouse lymphoma thymidine kinase locus gene mutation assay. Mutat. Res. 2003, 540:127-140.
4. Moore M.M., Honma M., Clements J., Bolcsfoldi G., Burlinson B., Cifone M., Clarke J., Delongchamp R., Durward R., Fellows M., Gollapudi B., Hou S., Jenkinson P., Lloyd M., Majeska J., Myhr B., O'Donovan M., Omori T., Riach C., San R., Stankowski L.F., Thakur A., Van Goethem F., Wakuri S., Yoshimura I. Mouse lymphoma thymidine kinase gene, mutation assay. Environ. Mol. Mutagen 2006, 47:1-5.
5. Moore M.M., Honma M., Clements J., Bolcsfoldi G., Burlinson B., Cifone M., Clarke J., Clay P., Doppalapudi R., Fellows M., Gollapudi B., Hou S., Jenkinson P., Muster W., Pant K., Kidd D.A., Lorge E., Lloyd M., Myhr B., O'Donovan M., Riach C., Stankowski L.F., Thakur A.K., Van Goethem F. Mouse lymphoma thymidine kinase mutation assay. Mutat. Res. 2007, 627:36-40.
6. Schisler M.R., Gollapudi B.B., Moore M.M. Evaluation of the mouse lymphoma mutation assay (MLA) data of the U.S. National Toxicology Program (NTP) using International Workshop on Genotoxicity Testing (IWGT) criteria. Environ. Mol. Mutagen 2010, 51:732.
7. OECD Detailed review paper on transgenic rodent mutation assays. Series on Testing and Assessment Number 103 OECD 2009.