Molecular mobility as an effective predictor of the physical stability of amorphous trehalose

Molecular Pharmaceutics

Volumn 9, Issue 11, 2012, Pages 3209-3217

  Bhardwaj, Sunny P ^a   Suryanarayanan, Raj ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

crystallization kinetics; crystallization onset; dielectric spectroscopy; molecular mobility; prediction; preparation method; trehalose

Indexed keywords

TREHALOSE; TREHALOSE DIHYDRATE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY; ENERGY; FREEZE DRYING; GLASS TRANSITION TEMPERATURE; HYDRATION; LIQUID; MOLECULAR DYNAMICS; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SPRAY DRYING; STRUCTURE ANALYSIS; TEMPERATURE DEPENDENCE; X RAY POWDER DIFFRACTION;

CRYSTALLIZATION; DIELECTRIC SPECTROSCOPY; FREEZE DRYING; KINETICS; MOTION; TEMPERATURE; THERMODYNAMICS; TREHALOSE; X-RAY DIFFRACTION;

EID: 84868575779     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp300302g     Document Type: Article

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