Crystallization of trehalose in frozen solutions and its phase behavior during drying

Pharmaceutical Research

Volumn 27, Issue 11, 2010, Pages 2374-2383

  Sundaramurthi, Prakash ^a,b   Patapoff, Thomas W ^c   Suryanarayanan, Raj ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b Scientific Affairs   (United States)

^c GENENTECH INC   (United States)

Author keywords

in situ freeze drying XRD; lyoprotectant crystallization; phase transformation; trehalose

Indexed keywords

BUFFER; SUCCINIC ACID; TREHALOSE;

AQUEOUS SOLUTION; ARTICLE; CARBOHYDRATE ANALYSIS; CONTROLLED STUDY; CRYSTALLIZATION; DEHYDRATION; DIFFERENTIAL SCANNING CALORIMETRY; FREEZE DRYING; PH; PHASE TRANSITION; PRIORITY JOURNAL; SYSTEM ANALYSIS; X RAY POWDER DIFFRACTION;

CRYSTALLIZATION; FREEZING; SOLUTIONS; TREHALOSE; X-RAY DIFFRACTION;

EID: 78549292420     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-010-0243-2     Document Type: Article

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