메뉴 건너뛰기




Volumn 38, Issue 8, 2012, Pages 768-779

Mechanisms of thrombosis in paraproteinemias: The effects of immunomodulatory drugs

Author keywords

immunomodulatory drugs; paraproteinemias; venous thrombosis

Indexed keywords

BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 8; BORTEZOMIB; CATHEPSIN G; CYCLIN DEPENDENT KINASE INHIBITOR 1A; DEXAMETHASONE; DOXORUBICIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; IMMUNOMODULATING AGENT; INTERLEUKIN 6; INTERLEUKIN 8; LENALIDOMIDE; MYC PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN P53; RANTES; RAS PROTEIN; SCATTER FACTOR; THALIDOMIDE; THROMBOMODULIN; THROMBOPLASTIN; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN; VINCRISTINE; VON WILLEBRAND FACTOR;

EID: 84868526939     PISSN: 00946176     EISSN: 10989064     Source Type: Journal    
DOI: 10.1055/s-0032-1328888     Document Type: Review
Times cited : (13)

References (160)
  • 2
    • 55249118893 scopus 로고    scopus 로고
    • Tissue factor in cancer
    • Rak J., Milsom C., Yu J. Tissue factor in cancer. Curr Opin Hematol: 2008; 15 5 522 528
    • (2008) Curr Opin Hematol , vol.15 , Issue.5 , pp. 522-528
    • Rak, J.1    Milsom, C.2    Yu, J.3
  • 3
    • 33746161986 scopus 로고    scopus 로고
    • Tissue factor as an effector of angiogenesis and tumor progression in hematological malignancies
    • DOI 10.1038/sj.leu.2404264, PII 2404264
    • López-Pedrera C., Barbarroja N., Dorado G., Siendones E., Velasco F. Tissue factor as an effector of angiogenesis and tumor progression in hematological malignancies. Leukemia: 2006; 20 8 1331 1340 (Pubitemid 44084043)
    • (2006) Leukemia , vol.20 , Issue.8 , pp. 1331-1340
    • Lopez-Pedrera, C.1    Barbarroja, N.2    Dorado, G.3    Siendones, E.4    Velasco, F.5
  • 4
    • 2942517677 scopus 로고    scopus 로고
    • Role of tissue factor in hemostasis, thrombosis, and vascular development
    • Mackman N. Role of tissue factor in hemostasis, thrombosis, and vascular development. Arterioscler Thromb Vasc Biol: 2004; 24 6 1015 1022
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , Issue.6 , pp. 1015-1022
    • MacKman, N.1
  • 5
    • 80055101700 scopus 로고    scopus 로고
    • Not exclusively tissue factor: Neutrophil extracellular traps provide another link between chemotherapy and thrombosis
    • Van Den Berg Y. W., Reitsma P. H. Not exclusively tissue factor: neutrophil extracellular traps provide another link between chemotherapy and thrombosis. J Thromb Haemost: 2011; 9 11 2311 2312
    • (2011) J Thromb Haemost , vol.9 , Issue.11 , pp. 2311-2312
    • Van Den Berg, Y.W.1    Reitsma, P.H.2
  • 6
    • 0030020590 scopus 로고    scopus 로고
    • In situ detection of tissue factor in vascular endothelial cells: Correlation with the malignant phenotype of human breast disease
    • DOI 10.1038/nm0296-209
    • Contrino J., Hair G., Kreutzer D. L., Rickles F. R. In situ detection of tissue factor in vascular endothelial cells: correlation with the malignant phenotype of human breast disease. Nat Med: 1996; 2 2 209 215 (Pubitemid 26054985)
    • (1996) Nature Medicine , vol.2 , Issue.2 , pp. 209-215
    • Contrino, J.1    Hair, G.2    Kreutzer, D.L.3    Rickles, F.R.4
  • 8
    • 78149352576 scopus 로고    scopus 로고
    • Microparticles in cancer
    • Rak J. Microparticles in cancer. Semin Thromb Hemost: 2010; 36 8 888 906
    • (2010) Semin Thromb Hemost , vol.36 , Issue.8 , pp. 888-906
    • Rak, J.1
  • 9
    • 33751169794 scopus 로고    scopus 로고
    • Procoagulant microparticles: Disrupting the vascular homeostasis equation
    • Morel O., Toti F., Hugel B., et al. Procoagulant microparticles: disrupting the vascular homeostasis equation? Arterioscler Thromb Vasc Biol: 2006; 26 12 2594 2604
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , Issue.12 , pp. 2594-2604
    • Morel, O.1    Toti, F.2    Hugel, B.3
  • 10
    • 33644557719 scopus 로고    scopus 로고
    • Emerging insights in tissue factor-dependent signaling events
    • Versteeg H. H., Ruf W. Emerging insights in tissue factor-dependent signaling events. Semin Thromb Hemost: 2006; 32 1 24 32
    • (2006) Semin Thromb Hemost , vol.32 , Issue.1 , pp. 24-32
    • Versteeg, H.H.1    Ruf, W.2
  • 12
    • 33846944344 scopus 로고    scopus 로고
    • Alternatively spliced tissue factor-one cut too many
    • Mackman N. Alternatively spliced tissue factor-one cut too many? Thromb Haemost: 2007; 97 1 5 8
    • (2007) Thromb Haemost , vol.97 , Issue.1 , pp. 5-8
    • MacKman, N.1
  • 13
    • 78651106510 scopus 로고    scopus 로고
    • Microparticle-associated tissue factor activity and venous thrombosis in multiple myeloma
    • Auwerda J. J., Yuana Y., Osanto S., et al. Microparticle-associated tissue factor activity and venous thrombosis in multiple myeloma. Thromb Haemost: 2011; 105 1 14 20
    • (2011) Thromb Haemost , vol.105 , Issue.1 , pp. 14-20
    • Auwerda, J.J.1    Yuana, Y.2    Osanto, S.3
  • 14
    • 0029097464 scopus 로고
    • Tissue factor expression correlates with histological grade in human pancreatic cancer
    • Kakkar A. K., Lemoine N. R., Scully M. F., Tebbutt S., Williamson R. C. Tissue factor expression correlates with histological grade in human pancreatic cancer. Br J Surg: 1995; 82 8 1101 1104
    • (1995) Br J Surg , vol.82 , Issue.8 , pp. 1101-1104
    • Kakkar, A.K.1    Lemoine, N.R.2    Scully, M.F.3    Tebbutt, S.4    Williamson, R.C.5
  • 16
    • 0034770081 scopus 로고    scopus 로고
    • The hemostatic system and angiogenesis in malignancy
    • DOI 10.1038/sj.neo.7900184
    • Wojtukiewicz M. Z., Sierko E., Klement P., Rak J. The hemostatic system and angiogenesis in malignancy. Neoplasia: 2001; 3 5 371 384 (Pubitemid 32988807)
    • (2001) Neoplasia , vol.3 , Issue.5 , pp. 371-384
    • Wojtukiewicz, M.Z.1    Sierko, E.2    Klement, P.3    Rak, J.4
  • 17
    • 34447626294 scopus 로고    scopus 로고
    • 2 leads to neutrophil recruitment to coronary artery endothelial cells
    • DOI 10.1016/j.thromres.2006.11.007, PII S0049384806004750
    • White M. C., McHowat J. Protease activation of calcium-independent phospholipase A2 leads to neutrophil recruitment to coronary artery endothelial cells. Thromb Res: 2007; 120 4 597 605 (Pubitemid 47094909)
    • (2007) Thrombosis Research , vol.120 , Issue.4 , pp. 597-605
    • White, M.C.1    McHowat, J.2
  • 18
    • 13944256192 scopus 로고    scopus 로고
    • PTEN and hypoxia regulate tissue factor expression and plasma coagulation by glioblastoma
    • DOI 10.1158/0008-5472.CAN-04-3376
    • Rong Y., Post D. E., Pieper R. O., Durden D. L., Van Meir E. G., Brat D. J. PTEN and hypoxia regulate tissue factor expression and plasma coagulation by glioblastoma. Cancer Res: 2005; 65 4 1406 1413 (Pubitemid 40270169)
    • (2005) Cancer Research , vol.65 , Issue.4 , pp. 1406-1413
    • Rong, Y.1    Post, D.E.2    Pieper, R.O.3    Durden, D.L.4    Van Meir, E.G.5    Brat, D.J.6
  • 19
    • 13544256266 scopus 로고    scopus 로고
    • Oncogenic events regulate tissue factor expression in colorectal cancer cells: Implications for tumor progression and angiogenesis
    • DOI 10.1182/blood-2004-05-2042
    • Yu J. L., May L., Lhotak V., et al. Oncogenic events regulate tissue factor expression in colorectal cancer cells: implications for tumor progression and angiogenesis. Blood: 2005; 105 4 1734 1741 (Pubitemid 40223697)
    • (2005) Blood , vol.105 , Issue.4 , pp. 1734-1741
    • Yu, J.L.1    May, L.2    Lhotak, V.3    Shahrzad, S.4    Shirasawa, S.5    Weitz, J.I.6    Coomber, B.L.7    Mackman, N.8    Rak, J.W.9
  • 20
    • 70350731332 scopus 로고    scopus 로고
    • Genetic link between cancer and thrombosis
    • Boccaccio C., Comoglio P. M. Genetic link between cancer and thrombosis. J Clin Oncol: 2009; 27 29 4827 4833
    • (2009) J Clin Oncol , vol.27 , Issue.29 , pp. 4827-4833
    • Boccaccio, C.1    Comoglio, P.M.2
  • 21
    • 0033970086 scopus 로고    scopus 로고
    • Epigenetic regulation of gene expression in cervical cancer cells by the tumor microenvironment
    • Denko N., Schindler C., Koong A., Laderoute K., Green C., Giaccia A. Epigenetic regulation of gene expression in cervical cancer cells by the tumor microenvironment. Clin Cancer Res: 2000; 6 2 480 487 (Pubitemid 30111467)
    • (2000) Clinical Cancer Research , vol.6 , Issue.2 , pp. 480-487
    • Denko, N.1    Schindler, C.2    Koong, A.3    Laderoute, K.4    Green, C.5    Giaccia, A.6
  • 22
    • 20444433198 scopus 로고    scopus 로고
    • In vitro procoagulant activity induced in endothelial cells by chemotherapy and antiangiogenic drug combinations: Modulation by lower-dose chemotherapy
    • DOI 10.1158/0008-5472.CAN-04-3156
    • Ma L., Francia G., Viloria-Petit A., et al. In vitro procoagulant activity induced in endothelial cells by chemotherapy and antiangiogenic drug combinations: modulation by lower-dose chemotherapy. Cancer Res: 2005; 65 12 5365 5373 (Pubitemid 40827350)
    • (2005) Cancer Research , vol.65 , Issue.12 , pp. 5365-5373
    • Ma, L.1    Francia, G.2    Viloria-Petit, A.3    Hicklin, D.J.4    Du Manoir, J.5    Rak, J.6    Kerbel, R.S.7
  • 23
    • 48749127220 scopus 로고    scopus 로고
    • Hypercoagulability and tissue factor gene upregulation in hematologic malignancies
    • Falanga A., Barbui T., Rickles F. R. Hypercoagulability and tissue factor gene upregulation in hematologic malignancies. Semin Thromb Hemost: 2008; 34 2 204 210
    • (2008) Semin Thromb Hemost , vol.34 , Issue.2 , pp. 204-210
    • Falanga, A.1    Barbui, T.2    Rickles, F.R.3
  • 24
    • 79951943894 scopus 로고    scopus 로고
    • Immunomodulatory drugs increase endothelial tissue factor expression in vitro
    • Valsami S., Ruf W., Leikauf M. S., Madon J., Kaech A., Asmis L. M. Immunomodulatory drugs increase endothelial tissue factor expression in vitro. Thromb Res: 2011; 127 3 264 271
    • (2011) Thromb Res , vol.127 , Issue.3 , pp. 264-271
    • Valsami, S.1    Ruf, W.2    Leikauf, M.S.3    Madon, J.4    Kaech, A.5    Asmis, L.M.6
  • 25
    • 84863784755 scopus 로고    scopus 로고
    • Absence of tissue factor expression by neoplastic plasma cells in multiple myeloma
    • February 15: 10.1038/leu.2012.43 [Epub ahead of print]
    • Cesarman-Maus G., Braggio E., Maldonado H., Fonseca R. Absence of tissue factor expression by neoplastic plasma cells in multiple myeloma. Leukemia 2012 February 15: 10.1038/leu.2012.43 [Epub ahead of print]
    • (2012) Leukemia
    • Cesarman-Maus, G.1    Braggio, E.2    Maldonado, H.3    Fonseca, R.4
  • 26
    • 0019422380 scopus 로고
    • Tumor shedding and coagulation
    • Dvorak H. F., Quay S. C., Orenstein N. S., et al. Tumor shedding and coagulation. Science: 1981; 212 4497 923 924 (Pubitemid 11120474)
    • (1981) Science , vol.212 , Issue.4497 , pp. 923-924
    • Dvorak, H.F.1    Quay, S.C.2    Orenstein, N.S.3
  • 27
    • 72549102588 scopus 로고    scopus 로고
    • Tumor-derived tissue factor-bearing microparticles are associated with venous thromboembolic events in malignancy
    • Zwicker J. I., Liebman H. A., Neuberg D., et al. Tumor-derived tissue factor-bearing microparticles are associated with venous thromboembolic events in malignancy. Clin Cancer Res: 2009; 15 22 6830 6840
    • (2009) Clin Cancer Res , vol.15 , Issue.22 , pp. 6830-6840
    • Zwicker, J.I.1    Liebman, H.A.2    Neuberg, D.3
  • 28
    • 77956621829 scopus 로고    scopus 로고
    • Endothelial-derived microparticles: Biological conveyors at the crossroad of inflammation, thrombosis and angiogenesis
    • Leroyer A. S., Anfosso F., Lacroix R., et al. Endothelial-derived microparticles: biological conveyors at the crossroad of inflammation, thrombosis and angiogenesis. Thromb Haemost: 2010; 104 3 456 463
    • (2010) Thromb Haemost , vol.104 , Issue.3 , pp. 456-463
    • Leroyer, A.S.1    Anfosso, F.2    Lacroix, R.3
  • 30
    • 33646128738 scopus 로고    scopus 로고
    • Increase of circulating neutrophil and platelet microparticles during acute vasculitis and hemodialysis
    • Daniel L., Fakhouri F., Joly D., et al. Increase of circulating neutrophil and platelet microparticles during acute vasculitis and hemodialysis. Kidney Int: 2006; 69 8 1416 1423
    • (2006) Kidney Int , vol.69 , Issue.8 , pp. 1416-1423
    • Daniel, L.1    Fakhouri, F.2    Joly, D.3
  • 31
    • 33645277840 scopus 로고    scopus 로고
    • Formation and fate of platelet microparticles
    • Flaumenhaft R. Formation and fate of platelet microparticles. Blood Cells Mol Dis: 2006; 36 2 182 187
    • (2006) Blood Cells Mol Dis , vol.36 , Issue.2 , pp. 182-187
    • Flaumenhaft, R.1
  • 32
    • 57749190349 scopus 로고    scopus 로고
    • Standardization of platelet-derived microparticle counting using calibrated beads and a Cytomics FC500 routine flow cytometer: A first step towards multicenter studies
    • Robert S., Poncelet P., Lacroix R., et al. Standardization of platelet-derived microparticle counting using calibrated beads and a Cytomics FC500 routine flow cytometer: a first step towards multicenter studies? J Thromb Haemost: 2009; 7 1 190 197
    • (2009) J Thromb Haemost , vol.7 , Issue.1 , pp. 190-197
    • Robert, S.1    Poncelet, P.2    Lacroix, R.3
  • 33
    • 77149127065 scopus 로고    scopus 로고
    • A multicolor flow cytometric assay for measurement of platelet-derived microparticles
    • Mobarrez F., Antovic J., Egberg N., et al. A multicolor flow cytometric assay for measurement of platelet-derived microparticles. Thromb Res: 2010; 125 3 e110 e116
    • (2010) Thromb Res , vol.125 , Issue.3
    • Mobarrez, F.1    Antovic, J.2    Egberg, N.3
  • 34
    • 51849135441 scopus 로고    scopus 로고
    • Flow cytometric measurement of microparticles: Pitfalls and protocol modifications
    • Shah M. D., Bergeron A. L., Dong J. F., López J. A. Flow cytometric measurement of microparticles: pitfalls and protocol modifications. Platelets: 2008; 19 5 365 372
    • (2008) Platelets , vol.19 , Issue.5 , pp. 365-372
    • Shah, M.D.1    Bergeron, A.L.2    Dong, J.F.3    López, J.A.4
  • 35
    • 60349099201 scopus 로고    scopus 로고
    • Flow cytometric analysis of cell membrane microparticles
    • Gelderman M. P., Simak J. Flow cytometric analysis of cell membrane microparticles. Methods Mol Biol: 2008; 484 79 93
    • (2008) Methods Mol Biol , vol.484 , pp. 79-93
    • Gelderman, M.P.1    Simak, J.2
  • 39
    • 12344303983 scopus 로고    scopus 로고
    • New horizons in the analysis of circulating cell-derived microparticles
    • DOI 10.2302/kjm.53.210
    • Horstman L. L., Jy W., Jimenez J. J., Bidot C., Ahn Y. S. New horizons in the analysis of circulating cell-derived microparticles. Keio J Med: 2004; 53 4 210 230 (Pubitemid 40139594)
    • (2004) Keio Journal of Medicine , vol.53 , Issue.4 , pp. 210-230
    • Horstman, L.L.1    Jy, W.2    Jimenez, J.J.3    Bidot, C.4    Ahn, Y.S.5
  • 40
    • 33646395655 scopus 로고    scopus 로고
    • Mechanism of platelet adhesion to von Willebrand factor and microparticle formation under high shear stress
    • Reininger A. J., Heijnen H. F., Schumann H., Specht H. M., Schramm W., Ruggeri Z. M. Mechanism of platelet adhesion to von Willebrand factor and microparticle formation under high shear stress. Blood: 2006; 107 9 3537 3545
    • (2006) Blood , vol.107 , Issue.9 , pp. 3537-3545
    • Reininger, A.J.1    Heijnen, H.F.2    Schumann, H.3    Specht, H.M.4    Schramm, W.5    Ruggeri, Z.M.6
  • 41
    • 34748888394 scopus 로고    scopus 로고
    • Risk of venous thromboembolism in lung cancer
    • DOI 10.1097/MCP.0b013e328209413c, PII 0006319820070900000003
    • Tesselaar M. E., Osanto S. Risk of venous thromboembolism in lung cancer. Curr Opin Pulm Med: 2007; 13 5 362 367 (Pubitemid 47472294)
    • (2007) Current Opinion in Pulmonary Medicine , vol.13 , Issue.5 , pp. 362-367
    • Tesselaar, M.E.T.1    Osanto, S.2
  • 43
    • 78149313092 scopus 로고    scopus 로고
    • Microparticles in thrombosis and hemostasis
    • Key N. S., Kwaan H. C. Microparticles in thrombosis and hemostasis. Semin Thromb Hemost: 2010; 36 8 805 806
    • (2010) Semin Thromb Hemost , vol.36 , Issue.8 , pp. 805-806
    • Key, N.S.1    Kwaan, H.C.2
  • 45
    • 77952548349 scopus 로고    scopus 로고
    • Increased microparticle tissue factor activity in cancer patients with venous thromboembolism
    • Manly D. A., Wang J., Glover S. L., et al. Increased microparticle tissue factor activity in cancer patients with venous thromboembolism. Thromb Res: 2010; 125 6 511 512
    • (2010) Thromb Res , vol.125 , Issue.6 , pp. 511-512
    • Manly, D.A.1    Wang, J.2    Glover, S.L.3
  • 46
    • 34848851036 scopus 로고    scopus 로고
    • A new standard of care for elderly patients with myeloma
    • DOI 10.1016/S0140-6736(07)61522-0, PII S0140673607615220
    • Palumbo A., Boccadoro M. A new standard of care for elderly patients with myeloma. Lancet: 2007; 370 9594 1191 1192 (Pubitemid 47503289)
    • (2007) Lancet , vol.370 , Issue.9594 , pp. 1191-1192
    • Palumbo, A.1    Boccadoro, M.2
  • 48
    • 58149380751 scopus 로고    scopus 로고
    • Genetic associations with thalidomide mediated venous thrombotic events in myeloma identified using targeted genotyping
    • Johnson D. C., Corthals S., Ramos C., et al. Genetic associations with thalidomide mediated venous thrombotic events in myeloma identified using targeted genotyping. Blood: 2008; 112 13 4924 4934
    • (2008) Blood , vol.112 , Issue.13 , pp. 4924-4934
    • Johnson, D.C.1    Corthals, S.2    Ramos, C.3
  • 49
    • 84856144389 scopus 로고    scopus 로고
    • Association study of selected genetic polymorphisms and occurrence of venous thromboembolism in patients with multiple myeloma who were treated with thalidomide
    • Almasi M., Sevcikova S., Slaby O., et al. Association study of selected genetic polymorphisms and occurrence of venous thromboembolism in patients with multiple myeloma who were treated with thalidomide. Clin LymphomaMyeloma Leuk: 2011; 11 414 420
    • (2011) Clin LymphomaMyeloma Leuk , vol.11 , pp. 414-420
    • Almasi, M.1    Sevcikova, S.2    Slaby, O.3
  • 50
    • 33745291997 scopus 로고    scopus 로고
    • Thromboembolism risk reduction in multiple myeloma patients treated with immunomodulatory drug combinations
    • DOI 10.1160/TH06-02-0080
    • Hussein M. A. Thromboembolism risk reduction in multiple myeloma patients treated with immunomodulatory drug combinations. Thromb Haemost: 2006; 95 6 924 930 (Pubitemid 43933748)
    • (2006) Thrombosis and Haemostasis , vol.95 , Issue.6 , pp. 924-930
    • Hussein, M.A.1
  • 52
    • 33746054911 scopus 로고    scopus 로고
    • Acquired resistance to activated protein C (aAPCR) in multiple myeloma is a transitory abnormality associated with an increased risk of venous thromboembolism
    • DOI 10.1111/j.1365-2141.2006.06208.x
    • Elice F., Fink L., Tricot G., Barlogie B., Zangari M. Acquired resistance to activated protein C (aAPCR) in multiple myeloma is a transitory abnormality associated with an increased risk of venous thromboembolism. Br J Haematol: 2006; 134 4 399 405 (Pubitemid 44079553)
    • (2006) British Journal of Haematology , vol.134 , Issue.4 , pp. 399-405
    • Elice, F.1    Fink, L.2    Tricot, G.3    Barlogie, B.4    Zangari, M.5
  • 54
    • 77956585456 scopus 로고    scopus 로고
    • Targeting the multiple myeloma hypoxic niche with TH-302, a hypoxia-activated prodrug
    • Hu J., Handisides D. R., Van Valckenborgh E., et al. Targeting the multiple myeloma hypoxic niche with TH-302, a hypoxia-activated prodrug. Blood: 2010; 116 9 1524 1527
    • (2010) Blood , vol.116 , Issue.9 , pp. 1524-1527
    • Hu, J.1    Handisides, D.R.2    Van Valckenborgh, E.3
  • 55
    • 78149468597 scopus 로고    scopus 로고
    • Low bone marrow oxygen tension and hypoxia-inducible factor-1α overexpression characterize patients with multiple myeloma: Role on the transcriptional and proangiogenic profiles of CD138(+) cells
    • Colla S., Storti P., Donofrio G., et al. Low bone marrow oxygen tension and hypoxia-inducible factor-1α overexpression characterize patients with multiple myeloma: role on the transcriptional and proangiogenic profiles of CD138(+) cells. Leukemia: 2010; 24 11 1967 1970
    • (2010) Leukemia , vol.24 , Issue.11 , pp. 1967-1970
    • Colla, S.1    Storti, P.2    Donofrio, G.3
  • 56
    • 77952314832 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-2 is a novel regulator of aberrant CXCL12 expression in multiple myeloma plasma cells
    • Martin S. K., Diamond P., Williams S. A., et al. Hypoxia-inducible factor-2 is a novel regulator of aberrant CXCL12 expression in multiple myeloma plasma cells. Haematologica: 2010; 95 5 776 784
    • (2010) Haematologica , vol.95 , Issue.5 , pp. 776-784
    • Martin, S.K.1    Diamond, P.2    Williams, S.A.3
  • 57
    • 77955795745 scopus 로고    scopus 로고
    • Hypoxia and activated VEGF/receptor pathway in multiple myeloma
    • Giatromanolaki A., Bai M., Margaritis D., et al. Hypoxia and activated VEGF/receptor pathway in multiple myeloma. Anticancer Res: 2010; 30 7 2831 2836
    • (2010) Anticancer Res , vol.30 , Issue.7 , pp. 2831-2836
    • Giatromanolaki, A.1    Bai, M.2    Margaritis, D.3
  • 59
    • 40949088476 scopus 로고    scopus 로고
    • Biology of hypoxia-inducible factor-2alpha in development and disease
    • DOI 10.1038/cdd.2008.17, PII CDD200817, The biology of Hypoxia-inducible factors
    • Patel S. A., Simon M. C. Biology of hypoxia-inducible factor-2 alpha in development and disease. Cell Death Differ: 2008; 15 4 628 634 (Pubitemid 351405065)
    • (2008) Cell Death and Differentiation , vol.15 , Issue.4 , pp. 628-634
    • Patel, S.A.1    Simon, M.C.2
  • 61
    • 67449138856 scopus 로고    scopus 로고
    • Targeting angiogenesis via a c-Myc/hypoxia-inducible factor-1 alpha-dependent pathway in multiple myeloma
    • Zhang J., Sattler M., Tonon G., et al. Targeting angiogenesis via a c-Myc/hypoxia-inducible factor-1 alpha-dependent pathway in multiple myeloma. Cancer Res: 2009; 69 12 5082 5090
    • (2009) Cancer Res , vol.69 , Issue.12 , pp. 5082-5090
    • Zhang, J.1    Sattler, M.2    Tonon, G.3
  • 62
    • 33746496671 scopus 로고    scopus 로고
    • Proteasomal inhibition attenuates transcriptional activity of hypoxia-inducible factor 1 (HIF-1) via specific effect on the HIF-1alpha C-terminal activation domain
    • DOI 10.1128/MCB.00552-06
    • Kaluz S., Kaluzová M., Stanbridge E. J. Proteasomal inhibition attenuates transcriptional activity of hypoxia-inducible factor 1 (HIF-1) via specific effect on the HIF-1 alpha C-terminal activation domain. Mol Cell Biol: 2006; 26 15 5895 5907 (Pubitemid 44134343)
    • (2006) Molecular and Cellular Biology , vol.26 , Issue.15 , pp. 5895-5907
    • Kaluz, S.1    Kaluzova, M.2    Stanbridge, E.J.3
  • 63
    • 42449130564 scopus 로고    scopus 로고
    • Bortezomib inhibits tumor adaptation to hypoxia by stimulating the FIH-mediated repression of hypoxia-inducible factor-1
    • Shin D. H., Chun Y. S., Lee D. S., Huang L. E., Park J. W. Bortezomib inhibits tumor adaptation to hypoxia by stimulating the FIH-mediated repression of hypoxia-inducible factor-1. Blood: 2008; 111 6 3131 3136
    • (2008) Blood , vol.111 , Issue.6 , pp. 3131-3136
    • Shin, D.H.1    Chun, Y.S.2    Lee, D.S.3    Huang, L.E.4    Park, J.W.5
  • 64
    • 60449115552 scopus 로고    scopus 로고
    • The anti-cancer drug lenalidomide inhibits angiogenesis and metastasis via multiple inhibitory effects on endothelial cell function in normoxic and hypoxic conditions
    • Lu L., Payvandi F., Wu L., et al. The anti-cancer drug lenalidomide inhibits angiogenesis and metastasis via multiple inhibitory effects on endothelial cell function in normoxic and hypoxic conditions. Microvasc Res: 2009; 77 2 78 86
    • (2009) Microvasc Res , vol.77 , Issue.2 , pp. 78-86
    • Lu, L.1    Payvandi, F.2    Wu, L.3
  • 65
    • 34247174944 scopus 로고    scopus 로고
    • Reduced pulmonary vascular reactivity after cold exposure to acute hypoxia: A role of Nitric Oxide (NO)
    • DOI 10.1089/ham.2006.1015
    • Watanabe K., Koizumi T., Ruan Z., Kubo K., Sakai A., Shibamoto T. Reduced pulmonary vascular reactivity after cold exposure to acute hypoxia: a role of nitric oxide (NO). High Alt Med Biol: 2007; 8 1 43 49 (Pubitemid 46587447)
    • (2007) High Altitude Medicine and Biology , vol.8 , Issue.1 , pp. 43-49
    • Watanabe, K.1    Koizumi, T.2    Ruan, Z.3    Kubo, K.4    Sakai, A.5    Shibamoto, T.6
  • 66
    • 34547873919 scopus 로고    scopus 로고
    • Hematopoietic progenitor cell mobilization results in hypoxia with increased hypoxia-inducible transcription factor-1alpha and vascular endothelial growth factor A in bone marrow
    • DOI 10.1634/stemcells.2006-0688
    • Lévesque J. P., Winkler I. G., Hendy J., et al. Hematopoietic progenitor cell mobilization results in hypoxia with increased hypoxia-inducible transcription factor-1 alpha and vascular endothelial growth factor A in bone marrow. Stem Cells: 2007; 25 8 1954 1965 (Pubitemid 47258173)
    • (2007) Stem Cells , vol.25 , Issue.8 , pp. 1954-1965
    • Levesque, J.-P.1    Winkler, I.G.2    Hendy, J.3    Williams, B.4    Helwani, F.5    Barbier, V.6    Nowlan, B.7    Nilsson, S.K.8
  • 68
    • 44449151030 scopus 로고    scopus 로고
    • Drug development of MET inhibitors: Targeting oncogene addiction and expedience
    • DOI 10.1038/nrd2530, PII NRD2530
    • Comoglio P. M., Giordano S., Trusolino L. Drug development of MET inhibitors: targeting oncogene addiction and expedience. Nat Rev Drug Discov: 2008; 7 6 504 516 (Pubitemid 351767118)
    • (2008) Nature Reviews Drug Discovery , vol.7 , Issue.6 , pp. 504-516
    • Comoglio, P.M.1    Giordano, S.2    Trusolino, L.3
  • 69
    • 0037478437 scopus 로고    scopus 로고
    • Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene
    • DOI 10.1016/S1535-6108(03)00085-0, PII S1535610803000850
    • Pennacchietti S., Michieli P., Galluzzo M., Mazzone M., Giordano S., Comoglio P. M. Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene. Cancer Cell: 2003; 3 4 347 361 (Pubitemid 38340304)
    • (2003) Cancer Cell , vol.3 , Issue.4 , pp. 347-361
    • Pennacchietti, S.1    Michieli, P.2    Galluzzo, M.3    Mazzone, M.4    Giordano, S.5    Comoglio, P.M.6
  • 71
    • 0025371467 scopus 로고
    • Development of venous occlusions in mice transgenic for the plasminogen activator inhibitor-1 gene
    • Erickson L. A., Fici G. J., Lund J. E., Boyle T. P., Polites H. G., Marotti K. R. Development of venous occlusions in mice transgenic for the plasminogen activator inhibitor-1 gene. Nature: 1990; 346 6279 74 76
    • (1990) Nature , vol.346 , Issue.6279 , pp. 74-76
    • Erickson, L.A.1    Fici, G.J.2    Lund, J.E.3    Boyle, T.P.4    Polites, H.G.5    Marotti, K.R.6
  • 72
    • 0034660437 scopus 로고    scopus 로고
    • Plasminogen-activator inhibitor type 1 and coronary artery disease
    • DOI 10.1056/NEJM200006153422406
    • Kohler H. P., Grant P. J. Plasminogen-activator inhibitor type 1 and coronary artery disease. N Engl J Med: 2000; 342 24 1792 1801 (Pubitemid 30390240)
    • (2000) New England Journal of Medicine , vol.342 , Issue.24 , pp. 1792-1801
    • Kohler, H.P.1    Grant, P.J.2
  • 73
    • 0033791318 scopus 로고    scopus 로고
    • Cyclooxygenases: Structural, cellular, and molecular biology
    • Smith W. L., DeWitt D. L., Garavito R. M. Cyclooxygenases: structural, cellular, and molecular biology. Annu Rev Biochem: 2000; 69 145 182
    • (2000) Annu Rev Biochem , vol.69 , pp. 145-182
    • Smith, W.L.1    Dewitt, D.L.2    Garavito, R.M.3
  • 74
    • 78649456121 scopus 로고    scopus 로고
    • The HGF/MET pathway as target for the treatment of multiple myeloma and B-cell lymphomas
    • Mahtouk K., Tjin E. P., Spaargaren M., Pals S. T. The HGF/MET pathway as target for the treatment of multiple myeloma and B-cell lymphomas. Biochim Biophys Acta: 2010; 1806 2 208 219
    • (2010) Biochim Biophys Acta , vol.1806 , Issue.2 , pp. 208-219
    • Mahtouk, K.1    Tjin, E.P.2    Spaargaren, M.3    Pals, S.T.4
  • 75
    • 0037381271 scopus 로고    scopus 로고
    • Elevated serum concentration of hepatocyte growth factor in patients with multiple myeloma: Correlation with markers of disease activity
    • DOI 10.1002/ajh.10304
    • Alexandrakis M. G., Passam F. H., Sfiridaki A., Kandidaki E., Roussou P., Kyriakou D. S. Elevated serum concentration of hepatocyte growth factor in patients with multiple myeloma: correlation with markers of disease activity. Am J Hematol: 2003; 72 4 229 233 (Pubitemid 36383972)
    • (2003) American Journal of Hematology , vol.72 , Issue.4 , pp. 229-233
    • Alexandrakis, M.G.1    Passam, F.H.2    Sfiridaki, A.3    Kandidaki, E.4    Roussou, P.5    Kyriakou, D.S.6
  • 76
    • 0032006829 scopus 로고    scopus 로고
    • Elevated serum concentrations of hepatocyte growth factor in patients with multiple myeloma
    • Seidel C., Borset M., Turesson I., et al. Elevated serum concentrations of hepatocyte growth factor in patients with multiple myeloma. Blood: 1998; 91 3 806 812 (Pubitemid 28078282)
    • (1998) Blood , vol.91 , Issue.3 , pp. 806-812
    • Seidel, C.1    Borset, M.2    Turesson, I.3    Abildgaard, N.4    Sundan, A.5    Waage, A.6
  • 78
    • 77649305672 scopus 로고    scopus 로고
    • Levels of angiogenic factors in patients with multiple myeloma correlate with treatment response
    • Pour L., Svachova H., Adam Z., et al. Levels of angiogenic factors in patients with multiple myeloma correlate with treatment response. Ann Hematol: 2010; 89 4 385 389
    • (2010) Ann Hematol , vol.89 , Issue.4 , pp. 385-389
    • Pour, L.1    Svachova, H.2    Adam, Z.3
  • 79
    • 77949479635 scopus 로고    scopus 로고
    • Treatment response to bortezomib in multiple myeloma correlates with plasma hepatocyte growth factor concentration and bone marrow thrombospondin concentration
    • Ludek P., Hana S., Zdenek A., et al. Treatment response to bortezomib in multiple myeloma correlates with plasma hepatocyte growth factor concentration and bone marrow thrombospondin concentration. Eur J Haematol: 2010; 84 4 332 336
    • (2010) Eur J Haematol , vol.84 , Issue.4 , pp. 332-336
    • Ludek, P.1    Hana, S.2    Zdenek, A.3
  • 80
    • 77949443655 scopus 로고    scopus 로고
    • Pretreatment hepatocyte growth factor and thrombospondin-1 levels predict response to high-dose chemotherapy for multiple myeloma
    • Pour L., Svachova H., Adam Z., et al. Pretreatment hepatocyte growth factor and thrombospondin-1 levels predict response to high-dose chemotherapy for multiple myeloma. Neoplasma: 2010; 57 1 29 34
    • (2010) Neoplasma , vol.57 , Issue.1 , pp. 29-34
    • Pour, L.1    Svachova, H.2    Adam, Z.3
  • 81
    • 0029825852 scopus 로고    scopus 로고
    • Hepatocyte growth factor and its receptor c-met in multiple myeloma
    • Börset M., Hjorth-Hansen H., Seidel C., Sundan A., Waage A. Hepatocyte growth factor and its receptor c-met in multiple myeloma. Blood: 1996; 88 10 3998 4004 (Pubitemid 26383124)
    • (1996) Blood , vol.88 , Issue.10 , pp. 3998-4004
    • Borset, M.1    Hjorth-Hansen, H.2    Seidel, C.3    Sundan, A.4    Waage, A.5
  • 83
    • 0031028327 scopus 로고    scopus 로고
    • Hepatocyte growth factor is constitutively produced by human bone marrow stromal cells and indirectly promotes hematopoiesis
    • Takai K., Hara J., Matsumoto K., et al. Hepatocyte growth factor is constitutively produced by human bone marrow stromal cells and indirectly promotes hematopoiesis. Blood: 1997; 89 5 1560 1565 (Pubitemid 27097448)
    • (1997) Blood , vol.89 , Issue.5 , pp. 1560-1565
    • Takai, K.1    Hara, J.2    Matsumoto, K.3    Hosoi, G.4    Osugi, Y.5    Tawa, A.6    Okada, S.7    Nakamura, T.8
  • 84
    • 0035672117 scopus 로고    scopus 로고
    • Response to thalidomide in progressive multiple myeloma is not mediated by inhibition of angiogenic cytokine secretion
    • DOI 10.1046/j.1365-2141.2001.03142.x
    • Neben K., Moehler T., Kraemer A., et al. Response to thalidomide in progressive multiple myeloma is not mediated by inhibition of angiogenic cytokine secretion. Br J Haematol: 2001; 115 3 605 608 (Pubitemid 34015650)
    • (2001) British Journal of Haematology , vol.115 , Issue.3 , pp. 605-608
    • Neben, K.1    Moehler, T.2    Kraemer, A.3    Benner, A.4    Egerer, G.5    Ho, A.D.6    Goldschmidt, H.7
  • 85
    • 0035544161 scopus 로고    scopus 로고
    • Influence of thalidomide on Bcl2 expression and proangiogenic cytokine levels in short-term culture of peripheral blood and bone marrow mononuclear cells of multiple myeloma patients
    • Dmoszyska A., Roliski J., Bojarska-Junak A., et al. Influence of thalidomide on Bcl2 expression and proangiogenic cytokine levels in short-term culture of peripheral blood and bone marrow mononuclear cells of multiple myeloma patients. Pol J Pharmacol: 2001; 53 6 709 713
    • (2001) Pol J Pharmacol , vol.53 , Issue.6 , pp. 709-713
    • Dmoszyska, A.1    Roliski, J.2    Bojarska-Junak, A.3
  • 87
    • 0031915348 scopus 로고    scopus 로고
    • Regulation of distinct steps of angiogenesis by different angiogenic molecules
    • Kumar R., Yoneda J., Bucana C. D., Fidler I. J. Regulation of distinct steps of angiogenesis by different angiogenic molecules. Int J Oncol: 1998; 12 4 749 757 (Pubitemid 28133565)
    • (1998) International Journal of Oncology , vol.12 , Issue.4 , pp. 749-757
    • Kumar, R.1    Yoneda, J.2    Bucana, C.D.3    Fidler, I.J.4
  • 88
    • 0032525250 scopus 로고    scopus 로고
    • Myeloid development is selectively disrupted in PU.1 null mice
    • Anderson K. L., Smith K. A., Conners K., McKercher S. R., Maki R. A., Torbett B. E. Myeloid development is selectively disrupted in PU.1 null mice. Blood: 1998; 91 10 3702 3710 (Pubitemid 28225738)
    • (1998) Blood , vol.91 , Issue.10 , pp. 3702-3710
    • Anderson, K.L.1    Smith, K.A.2    Conners, K.3    McKercher, S.R.4    Maki, R.A.5    Torbett, B.E.6
  • 89
    • 0023951925 scopus 로고
    • Cathepsin G is a strong platelet agonist released by neutrophils
    • Selak M. A., Chignard M., Smith J. B. Cathepsin G is a strong platelet agonist released by neutrophils. Biochem J: 1988; 251 1 293 299
    • (1988) Biochem J , vol.251 , Issue.1 , pp. 293-299
    • Selak, M.A.1    Chignard, M.2    Smith, J.B.3
  • 90
    • 0028006809 scopus 로고
    • Neutrophil proteinase cathepsin G is proteolytically active on the human platelet glycoprotein Ib-IX receptor: Characterization of the cleavage sites within the glycoprotein Ibalpha subunit
    • Pidard D., Renesto P., Berndt M. C., Rabhi S., Clemetson K. J., Chignard M. Neutrophil proteinase cathepsin G is proteolytically active on the human platelet glycoprotein Ib-IX receptor: characterization of the cleavage sites within the glycoprotein Ib alpha subunit. Biochem J: 1994; 303 489 498 (Pubitemid 24317330)
    • (1994) Biochemical Journal , vol.303 , Issue.2 , pp. 489-498
    • Pidard, D.1    Renesto, P.2    Berndt, M.C.3    Rabhi, S.4    Clemetson, K.J.5    Chignard, M.6
  • 91
    • 0030048270 scopus 로고    scopus 로고
    • The phospholipase C/protein kinase C pathway is involved in cathepsin G-induced human platelet activation: Comparison with thrombin
    • Si-Tahar M., Renesto P., Falet H., Rendu F., Chignard M. The phospholipase C/protein kinase C pathway is involved in cathepsin G-induced human platelet activation: comparison with thrombin. Biochem J: 1996; 313 Pt 2 401 408 (Pubitemid 26030126)
    • (1996) Biochemical Journal , vol.313 , Issue.2 , pp. 401-408
    • Si-Tahar, M.1    Renesto, P.2    Falet, H.3    Rendu, F.4    Chignard, M.5
  • 92
    • 38349162791 scopus 로고    scopus 로고
    • Cathepsin G, a leukocyte protease, activates coagulation factor VIII
    • Gale A. J., Rozenshteyn D. Cathepsin G, a leukocyte protease, activates coagulation factor VIII. Thromb Haemost: 2008; 99 1 44 51
    • (2008) Thromb Haemost , vol.99 , Issue.1 , pp. 44-51
    • Gale, A.J.1    Rozenshteyn, D.2
  • 93
    • 77449111211 scopus 로고    scopus 로고
    • Immunomodulatory derivatives induce PU.1 down-regulation, myeloid maturation arrest, and neutropenia
    • Pal R., Monaghan S. A., Hassett A. C., et al. Immunomodulatory derivatives induce PU.1 down-regulation, myeloid maturation arrest, and neutropenia. Blood: 2010; 115 3 605 614
    • (2010) Blood , vol.115 , Issue.3 , pp. 605-614
    • Pal, R.1    Monaghan, S.A.2    Hassett, A.C.3
  • 94
    • 0031963766 scopus 로고    scopus 로고
    • Transcriptional activation of the factor VIII gene in liver cell lines by interleukin-6
    • Stirling D., Hannant W. A., Ludlam C. A. Transcriptional activation of the factor VIII gene in liver cell lines by interleukin-6. Thromb Haemost: 1998; 79 1 74 78 (Pubitemid 28037061)
    • (1998) Thrombosis and Haemostasis , vol.79 , Issue.1 , pp. 74-78
    • Stirling, D.1    Hannant, W.A.2    Ludlam, C.A.3
  • 96
    • 0026185304 scopus 로고
    • Hemostatic evaluation of Sarns/3M-VAD implantation in calves
    • Amrani D. L., Christensen C., Hauerwas L., et al. Hemostatic evaluation of Sarns/3M-VAD implantation in calves. ASAIO Trans: 1991; 37 3 M308 M310
    • (1991) ASAIO Trans , vol.37 , Issue.3
    • Amrani, D.L.1    Christensen, C.2    Hauerwas, L.3
  • 97
    • 0036061080 scopus 로고    scopus 로고
    • Serum tumour necrosis factor-alpha and transforming growth factor-beta levels in chronic hepatitis C patients are immunomodulated by therapy
    • Neuman M. G., Benhamou J. P., Bourliere M., et al. Serum tumour necrosis factor-alpha and transforming growth factor-beta levels in chronic hepatitis C patients are immunomodulated by therapy. Cytokine: 2002; 17 2 108 117
    • (2002) Cytokine , vol.17 , Issue.2 , pp. 108-117
    • Neuman, M.G.1    Benhamou, J.P.2    Bourliere, M.3
  • 98
    • 0027162435 scopus 로고
    • C-reactive protein induces human peripheral blood monocytes to synthesize tissue factor
    • Cermak J., Key N. S., Bach R. R., Balla J., Jacob H. S., Vercellotti G. M. C-reactive protein induces human peripheral blood monocytes to synthesize tissue factor. Blood: 1993; 82 2 513 520 (Pubitemid 23206115)
    • (1993) Blood , vol.82 , Issue.2 , pp. 513-520
    • Cermak, J.1    Key, N.S.2    Bach, R.R.3    Balla, J.4    Jacob, H.S.5    Vercellotti, G.M.6
  • 99
    • 0033862227 scopus 로고    scopus 로고
    • The factor VIII acute phase response requires the participation of NFkappaB and C/EBP
    • Begbie M., Notley C., Tinlin S., Sawyer L., Lillicrap D. The Factor VIII acute phase response requires the participation of NFkappaB and C/EBP. Thromb Haemost: 2000; 84 2 216 222 (Pubitemid 30601466)
    • (2000) Thrombosis and Haemostasis , vol.84 , Issue.2 , pp. 216-222
    • Begbie, M.1    Notley, C.2    Tinlin, S.3    Sawyer, L.4    Lillicrap, D.5
  • 100
    • 0023089665 scopus 로고
    • Endotoxin enhances tissue factor and suppresses thrombomodulin expression of human vascular endothelium in vitro
    • Moore K. L., Andreoli S. P., Esmon N. L., Esmon C. T., Bang N. U. Endotoxin enhances tissue factor and suppresses thrombomodulin expression of human vascular endothelium in vitro. J Clin Invest: 1987; 79 1 124 130 (Pubitemid 17232509)
    • (1987) Journal of Clinical Investigation , vol.79 , Issue.1 , pp. 124-130
    • Moore, K.L.1    Andreoli, S.P.2    Esmon, N.L.3
  • 102
    • 84555206129 scopus 로고    scopus 로고
    • Bleeding and thrombosis in multiple myeloma and related plasma cell disorders
    • Coppola A., Tufano A., Di Capua M., Franchini M. Bleeding and thrombosis in multiple myeloma and related plasma cell disorders. Semin Thromb Hemost: 2011; 37 8 929 945
    • (2011) Semin Thromb Hemost , vol.37 , Issue.8 , pp. 929-945
    • Coppola, A.1    Tufano, A.2    Di Capua, M.3    Franchini, M.4
  • 103
  • 105
    • 41949131848 scopus 로고    scopus 로고
    • Prospective evaluation of coagulopathy in multiple myeloma patients before, during and after various chemotherapeutic regimens
    • van Marion A. M., Auwerda J. J., Lisman T., et al. Prospective evaluation of coagulopathy in multiple myeloma patients before, during and after various chemotherapeutic regimens. Leuk Res: 2008; 32 7 1078 1084
    • (2008) Leuk Res , vol.32 , Issue.7 , pp. 1078-1084
    • Van Marion, A.M.1    Auwerda, J.J.2    Lisman, T.3
  • 106
    • 0034700846 scopus 로고    scopus 로고
    • New insights into role of microenvironment in multiple myeloma
    • DOI 10.1016/S0140-6736(00)00019-2
    • Tricot G. New insights into role of microenvironment in multiple myeloma. Lancet: 2000; 355 9200 248 250 (Pubitemid 30068513)
    • (2000) Lancet , vol.355 , Issue.9200 , pp. 248-250
    • Tricot, G.1
  • 107
    • 0034517587 scopus 로고    scopus 로고
    • The role of interleukin-6 and interleukin-6/interleukin-6 receptor-alpha complex in the pathogenesis of multiple myeloma
    • Barillé S., Bataille R., Amiot M. The role of interleukin-6 and interleukin-6/interleukin-6 receptor-alpha complex in the pathogenesis of multiple myeloma. Eur Cytokine Netw: 2000; 11 4 546 551 (Pubitemid 32044237)
    • (2000) European Cytokine Network , vol.11 , Issue.4 , pp. 546-551
    • Barille, S.1    Bataille, R.2    Amiot, M.3
  • 108
    • 41149168649 scopus 로고    scopus 로고
    • Lenalidomide for the treatment of B-cell malignancies
    • Chanan-Khan A. A., Cheson B. D. Lenalidomide for the treatment of B-cell malignancies. J Clin Oncol: 2008; 26 9 1544 1552
    • (2008) J Clin Oncol , vol.26 , Issue.9 , pp. 1544-1552
    • Chanan-Khan, A.A.1    Cheson, B.D.2
  • 109
    • 70349153856 scopus 로고    scopus 로고
    • Immune dysfunction in chronic lymphocytic leukemia T cells and lenalidomide as an immunomodulatory drug
    • Ramsay A. G., Gribben J. G. Immune dysfunction in chronic lymphocytic leukemia T cells and lenalidomide as an immunomodulatory drug. Haematologica: 2009; 94 9 1198 1202
    • (2009) Haematologica , vol.94 , Issue.9 , pp. 1198-1202
    • Ramsay, A.G.1    Gribben, J.G.2
  • 110
    • 80052882005 scopus 로고    scopus 로고
    • Inflammation, TNFα and endothelial dysfunction link lenalidomide to venous thrombosis in chronic lymphocytic leukemia
    • Aue G., Nelson Lozier J., Tian X., et al. Inflammation, TNFα and endothelial dysfunction link lenalidomide to venous thrombosis in chronic lymphocytic leukemia. Am J Hematol: 2011; 86 10 835 840
    • (2011) Am J Hematol , vol.86 , Issue.10 , pp. 835-840
    • Aue, G.1    Nelson Lozier, J.2    Tian, X.3
  • 111
    • 17044393376 scopus 로고    scopus 로고
    • The influence of thalidomide therapy on cytokine secretion, immunophenotype, BCL-2 expression and microvessel density in patients with resistant or relapsed multiple myeloma
    • Dmoszynska A., Podhorecka M., Manko J., Bojarska-Junak A., Rolinski J., Skomra D. The influence of thalidomide therapy on cytokine secretion, immunophenotype, BCL-2 expression and microvessel density in patients with resistant or relapsed multiple myeloma. Neoplasma: 2005; 52 2 175 181
    • (2005) Neoplasma , vol.52 , Issue.2 , pp. 175-181
    • Dmoszynska, A.1    Podhorecka, M.2    Manko, J.3    Bojarska-Junak, A.4    Rolinski, J.5    Skomra, D.6
  • 112
    • 63149146167 scopus 로고    scopus 로고
    • Pathogenesis and management of bleeding and thrombosis in plasma cell dyscrasias
    • Eby C. Pathogenesis and management of bleeding and thrombosis in plasma cell dyscrasias. Br J Haematol: 2009; 145 2 151 163
    • (2009) Br J Haematol , vol.145 , Issue.2 , pp. 151-163
    • Eby, C.1
  • 113
    • 0022615123 scopus 로고
    • A myeloma paraprotein with specificity for platelet glycoprotein IIIa in a patient with a fatal bleeding disorder
    • DiMinno G., Coraggio F., Cerbone A. M., et al. A myeloma paraprotein with specificity for platelet glycoprotein IIIa in a patient with a fatal bleeding disorder. J Clin Invest: 1986; 77 1 157 164 (Pubitemid 16101214)
    • (1986) Journal of Clinical Investigation , vol.77 , Issue.1 , pp. 157-164
    • DiMinno, G.1    Coraggio, F.2    Cerbone, A.M.3
  • 114
    • 66149109580 scopus 로고    scopus 로고
    • Lenalidomide, Adriamycin, and dexamethasone (RAD) in patients with relapsed and refractory multiple myeloma: A report from the German Myeloma Study Group DSMM (Deutsche Studiengruppe Multiples Myelom)
    • Knop S., Gerecke C., Liebisch P., et al. Lenalidomide, Adriamycin, and dexamethasone (RAD) in patients with relapsed and refractory multiple myeloma: a report from the German Myeloma Study Group DSMM (Deutsche Studiengruppe Multiples Myelom). Blood: 2009; 113 18 4137 4143
    • (2009) Blood , vol.113 , Issue.18 , pp. 4137-4143
    • Knop, S.1    Gerecke, C.2    Liebisch, P.3
  • 118
    • 33745002747 scopus 로고    scopus 로고
    • Thrombosis and bleeding in polycythemia vera and essential thrombocythemia: Pathogenetic mechanisms and prevention
    • DOI 10.1016/j.beha.2005.07.011, PII S152169260500099X
    • Landolfi R., Cipriani M. C., Novarese L. Thrombosis and bleeding in polycythemia vera and essential thrombocythemia: pathogenetic mechanisms and prevention. Best Pract Res Clin Haematol: 2006; 19 3 617 633 (Pubitemid 43863144)
    • (2006) Best Practice and Research: Clinical Haematology , vol.19 , Issue.3 , pp. 617-633
    • Landolfi, R.1    Cipriani, M.C.2    Novarese, L.3
  • 120
    • 0026491075 scopus 로고
    • The effect of fibrin structure on fibrinolysis
    • Gabriel D. A., Muga K., Boothroyd E. M. The effect of fibrin structure on fibrinolysis. J Biol Chem: 1992; 267 34 24259 24263
    • (1992) J Biol Chem , vol.267 , Issue.34 , pp. 24259-24263
    • Gabriel, D.A.1    Muga, K.2    Boothroyd, E.M.3
  • 121
    • 0018197812 scopus 로고
    • Differences between type I autoimmune inhibitors of fibrin stabilization in two patients with severe hemorrhagic disorder
    • Lopaciuk S., Bykowska K., McDonagh J. M., et al. Difference between type I autoimmune inhibitors of fibrin stabilization in two patients with severe hemorrhagic disorder. J Clin Invest: 1978; 61 5 1196 1203 (Pubitemid 8324144)
    • (1978) Journal of Clinical Investigation , vol.61 , Issue.5 , pp. 1196-1203
    • Lopaciuk, S.1    Bykowska, K.2    McDonagh, J.M.3
  • 122
    • 0023957280 scopus 로고
    • Impaired fibrin formation in a patient with multiple myeloma presenting the "gelationo" phenomenon
    • Ideguchi H., Suehiro T., Ohike M., et al. Impaired fibrin formation in a patient with multiple myeloma presenting the "gelationo" phenomenon. Nippon Ketsueki Gakkai Zasshi: 1988; 51 1 109 117
    • (1988) Nippon Ketsueki Gakkai Zasshi , vol.51 , Issue.1 , pp. 109-117
    • Ideguchi, H.1    Suehiro, T.2    Ohike, M.3
  • 123
    • 0014800884 scopus 로고
    • Abnormal fibrin ultrastructure, polymerization, and clot retraction in multiple myeloma
    • Lackner H., Hunt V., Zucker M. B., Pearson J. Abnormal fibrin ultrastructure, polymerization, and clot retraction in multiple myeloma. Br J Haematol: 1970; 18 6 625 636
    • (1970) Br J Haematol , vol.18 , Issue.6 , pp. 625-636
    • Lackner, H.1    Hunt, V.2    Zucker, M.B.3    Pearson, J.4
  • 124
    • 0014807585 scopus 로고
    • Plasma cell myeloma associated with an unusual myeloma protein causing impairment of fibrin aggregation and platelet function in a patient with multiple malignancy
    • Cohen I., Amir J., Ben-Shaul Y., Pick A., De Vries A. Plasma cell myeloma associated with an unusual myeloma protein causing impairment of fibrin aggregation and platelet function in a patient with multiple malignancy. Am J Med: 1970; 48 6 766 776
    • (1970) Am J Med , vol.48 , Issue.6 , pp. 766-776
    • Cohen, I.1    Amir, J.2    Ben-Shaul, Y.3    Pick, A.4    De Vries, A.5
  • 126
    • 54749153706 scopus 로고    scopus 로고
    • Acquired dysfibrinogenemia secondary to multiple myeloma
    • Kotlín R., Sobotková A., Riedel T., et al. Acquired dysfibrinogenemia secondary to multiple myeloma. Acta Haematol: 2008; 120 2 75 81
    • (2008) Acta Haematol , vol.120 , Issue.2 , pp. 75-81
    • Kotlín, R.1    Sobotková, A.2    Riedel, T.3
  • 127
    • 0015292719 scopus 로고
    • IgA pyroglobulin, hyperviscosity syndrome and coagulation abnormality in a patient with multiple myeloma
    • Sugai S. IgA pyroglobulin, hyperviscosity syndrome and coagulation abnormality in a patient with multiple myeloma. Blood: 1972; 39 2 224 237
    • (1972) Blood , vol.39 , Issue.2 , pp. 224-237
    • Sugai, S.1
  • 128
    • 27244439233 scopus 로고    scopus 로고
    • The measurement and application of thrombin generation
    • DOI 10.1111/j.1365-2141.2005.05612.x
    • Baglin T. The measurement and application of thrombin generation. Br J Haematol: 2005; 130 5 653 661 (Pubitemid 43906639)
    • (2005) British Journal of Haematology , vol.130 , Issue.5 , pp. 653-661
    • Baglin, T.1
  • 129
    • 61549101213 scopus 로고    scopus 로고
    • Biomarkers and venous thromboembolism
    • Pabinger I., Ay C. Biomarkers and venous thromboembolism. Arterioscler Thromb Vasc Biol: 2009; 29 3 332 336
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , Issue.3 , pp. 332-336
    • Pabinger, I.1    Ay, C.2
  • 130
    • 33751210094 scopus 로고    scopus 로고
    • Thrombin generation, a function test of the haemostatic-thrombotic system
    • DOI 10.1160/TH06-07-0408
    • Hemker H. C., Al Dieri R., De Smedt E., Béguin S. Thrombin generation, a function test of the haemostatic-thrombotic system. Thromb Haemost: 2006; 96 5 553 561 (Pubitemid 44782533)
    • (2006) Thrombosis and Haemostasis , vol.96 , Issue.5 , pp. 553-561
    • Hemker, H.C.1    Al Dieri, R.2    De Smedt, E.3    Beguin, S.4
  • 131
    • 38649120510 scopus 로고    scopus 로고
    • In vitro study of the hypercoagulable state in multiple myeloma patients treated or not with thalidomide
    • DOI 10.1016/j.thromres.2007.05.016, PII S0049384807002307
    • Petropoulou A. D., Gerotziafas G. T., Samama M. M., Hatmi M., Rendu F., Elalamy I. In vitro study of the hypercoagulable state in multiple myeloma patients treated or not with thalidomide. Thromb Res: 2008; 121 4 493 497 (Pubitemid 351174267)
    • (2008) Thrombosis Research , vol.121 , Issue.4 , pp. 493-497
    • Petropoulou, A.D.1    Gerotziafas, G.T.2    Samama, M.M.3    Hatmi, M.4    Rendu, F.5    Elalamy, I.6
  • 132
    • 0024558370 scopus 로고
    • The roles of protein C and thrombomodulin in the regulation of blood coagulation
    • Esmon C. T. The roles of protein C and thrombomodulin in the regulation of blood coagulation. J Biol Chem: 1989; 264 9 4743 4746 (Pubitemid 19092874)
    • (1989) Journal of Biological Chemistry , vol.264 , Issue.9 , pp. 4743-4746
    • Esmon, C.T.1
  • 136
    • 77952647321 scopus 로고    scopus 로고
    • Thalidomide-dexamethasone as up-front therapy for patients with newly diagnosed multiple myeloma: Thrombophilic alterations, thrombotic complications, and thromboprophylaxis with low-dose warfarin
    • Cini M., Zamagni E., Valdré L., et al. Thalidomide-dexamethasone as up-front therapy for patients with newly diagnosed multiple myeloma: thrombophilic alterations, thrombotic complications, and thromboprophylaxis with low-dose warfarin. Eur J Haematol: 2010; 84 6 484 492
    • (2010) Eur J Haematol , vol.84 , Issue.6 , pp. 484-492
    • Cini, M.1    Zamagni, E.2    Valdré, L.3
  • 137
    • 4644316831 scopus 로고    scopus 로고
    • Thalidomide protects endothelial cells from doxorubicin-induced apoptosis but alters cell morphology
    • DOI 10.1046/j.1538-7933.2003.00573.x
    • Kaushal V., Kaushal G. P., Melkaveri S. N., Mehta P. Thalidomide protects endothelial cells from doxorubicin-induced apoptosis but alters cell morphology. J Thromb Haemost: 2004; 2 2 327 334 (Pubitemid 40186049)
    • (2004) Journal of Thrombosis and Haemostasis , vol.2 , Issue.2 , pp. 327-334
    • Kaushal, V.1    Kaushal, G.P.2    Melkaveri, S.N.3    Mehta, P.4
  • 138
  • 139
    • 0017136389 scopus 로고
    • Platelet function in the Chediak-Higashi syndrome
    • Buchanan G. R., Handin R. I. Platelet function in the Chediak-Higashi syndrome. Blood: 1976; 47 6 941 948
    • (1976) Blood , vol.47 , Issue.6 , pp. 941-948
    • Buchanan, G.R.1    Handin, R.I.2
  • 140
    • 34548314245 scopus 로고    scopus 로고
    • Prophylaxis in Von Willebrand disease
    • DOI 10.1007/s00277-007-0343-1
    • Franchini M., Targher G., Lippi G. Prophylaxis in von Willebrand disease. Ann Hematol: 2007; 86 10 699 704 (Pubitemid 47337931)
    • (2007) Annals of Hematology , vol.86 , Issue.10 , pp. 699-704
    • Franchini, M.1    Targher, G.2    Lippi, G.3
  • 142
    • 1242330853 scopus 로고    scopus 로고
    • Acquired von Willebrand syndrome 2004: International Registry. Diagnosis and management from online to bedside
    • Federici A. B., Budde U., Rand J. H. Acquired von Willebrand syndrome 2004: international registrydiagnosis and management from online to bedside. Hamostaseologie: 2004; 24 1 50 55 (Pubitemid 38233047)
    • (2004) Hamostaseologie , vol.24 , Issue.1 , pp. 50-55
    • Federici, A.B.1    Budde, U.2    Rand, J.H.3
  • 144
    • 0027160838 scopus 로고
    • Expression of GpIb on plasma cells in a patient with monoclonal IgG and acquired von Willebrand disease
    • Scrobohaci M. L., Daniel M. T., Levy Y., Marolleau J. P., Brouet J. C. Expression of GpIb on plasma cells in a patient with monoclonal IgG and acquired von Willebrand disease. Br J Haematol: 1993; 84 3 471 475 (Pubitemid 23224164)
    • (1993) British Journal of Haematology , vol.84 , Issue.3 , pp. 471-475
    • Scrobohaci, M.-L.1    Daniel, M.-T.2    Levy, Y.3    Marolleau, J.-P.4    Brouet, J.-C.5
  • 145
    • 0026770243 scopus 로고
    • Acquired von Willebrand's disease due to excessive fibrinolysis
    • Eikenboom J. C., van der Meer F. J., Briët E. Acquired von Willebrand's disease due to excessive fibrinolysis. Br J Haematol: 1992; 81 4 618 620
    • (1992) Br J Haematol , vol.81 , Issue.4 , pp. 618-620
    • Eikenboom, J.C.1    Van Der Meer, F.J.2    Briët, E.3
  • 146
    • 18844374852 scopus 로고    scopus 로고
    • Characterization of a myeloma patient with a life-threatening hemorrhagic diathesis: Presence of a lambda dimer protein inhibiting shear-induced platelet aggregation by binding to the A1 domain of von Willebrand factor
    • DOI 10.1160/TH04-03-0193
    • Shinagawa A., Kojima H., Berndt M. C., et al. Characterization of a myeloma patient with a life-threatening hemorrhagic diathesis: presence of a lambda dimer protein inhibiting shear-induced platelet aggregation by binding to the A1 domain of von Willebrand factor. Thromb Haemost: 2005; 93 5 889 896 (Pubitemid 40691546)
    • (2005) Thrombosis and Haemostasis , vol.93 , Issue.5 , pp. 889-896
    • Shinagawa, A.1    Kojima, H.2    Berndt, M.C.3    Kaneko, S.4    Suzukawa, K.5    Hasegawa, Y.6    Shigeta, O.7    Nagasawa, T.8
  • 147
    • 0028131862 scopus 로고
    • Acquired von Willebrand disease caused by an autoantibody selectively inhibiting the binding of von Willebrand factor to collagen
    • van Genderen P. J., Vink T., Michiels J. J., van 't Veer M. B., Sixma J. J., van Vliet H. H. Acquired von Willebrand disease caused by an autoantibody selectively inhibiting the binding of von Willebrand factor to collagen. Blood: 1994; 84 10 3378 3384 (Pubitemid 24352900)
    • (1994) Blood , vol.84 , Issue.10 , pp. 3378-3384
    • Van Genderen, P.J.J.1    Vink, T.2    Michiels, J.J.3    Van 'T Veer, M.B.4    Sixma, J.J.5    Van Vliet, H.H.D.M.6
  • 148
    • 0027446268 scopus 로고
    • Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: Prediction of a cofactor to activated protein C
    • DOI 10.1073/pnas.90.3.1004
    • Dahlbäck B., Carlsson M., Svensson P. J. Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C. Proc Natl Acad Sci USA: 1993; 90 3 1004 1008 (Pubitemid 23053939)
    • (1993) Proceedings of the National Academy of Sciences of the United States of America , vol.90 , Issue.3 , pp. 1004-1008
    • Dahlback, B.1    Carlsson, M.2    Svensson, P.J.3
  • 150
    • 0027234122 scopus 로고
    • Homocysteinemia: Association of a metabolic disorder with vascular disease and thrombosis
    • DOI 10.1016/0049-3848(93)90160-P
    • Rees M. M., Rodgers G. M. Homocysteinemia: association of a metabolic disorder with vascular disease and thrombosis. Thromb Res: 1993; 71 5 337 359 (Pubitemid 23244324)
    • (1993) Thrombosis Research , vol.71 , Issue.5 , pp. 337-359
    • Rees, M.M.1    Rodgers, G.M.2
  • 151
    • 77949304898 scopus 로고    scopus 로고
    • APC resistance: Biological basis and acquired influences
    • Castoldi E., Rosing J. APC resistance: biological basis and acquired influences. J Thromb Haemost: 2010; 8 3 445 453
    • (2010) J Thromb Haemost , vol.8 , Issue.3 , pp. 445-453
    • Castoldi, E.1    Rosing, J.2
  • 153
    • 0029016335 scopus 로고
    • Cellular interactions in tissue factor expression by blood monocytes
    • Osterud B. Cellular interactions in tissue factor expression by blood monocytes. Blood Coagul Fibrinolysis: 1995; 6 01 S20 S25
    • (1995) Blood Coagul Fibrinolysis , vol.6 , Issue.1
    • Osterud, B.1
  • 156
    • 0030805620 scopus 로고    scopus 로고
    • Gene-environment interaction in the determination of levels of haemostatic variables involved in thrombosis and fibrinolysis
    • Humphries S. E., Panahloo A., Montgomery H. E., Green F., Yudkin J. Gene-environment interaction in the determination of levels of haemostatic variables involved in thrombosis and fibrinolysis. Thromb Haemost: 1997; 78 1 457 461 (Pubitemid 27289284)
    • (1997) Thrombosis and Haemostasis , vol.78 , Issue.1 , pp. 457-461
    • Humphries, S.E.1    Panahloo, A.2    Montgomery, H.E.3    Green, F.4    Yudkin, J.5
  • 158
    • 0034930752 scopus 로고    scopus 로고
    • Cancer and thrombosis revisited
    • DOI 10.1054/blre.2001.0149
    • Hoffman R., Haim N., Brenner B. Cancer and thrombosis revisited. Blood Rev: 2001; 15 2 61 67 (Pubitemid 32619559)
    • (2001) Blood Reviews , vol.15 , Issue.2 , pp. 61-67
    • Hoffman, R.1    Haim, N.2    Brenner, B.3
  • 159
    • 33750812822 scopus 로고    scopus 로고
    • Clinical evaluation of a new functional test for detection of activated protein C resistance (Pefakit APC-R Factor V Leiden) at two centers in Europe and the USA
    • DOI 10.1016/j.thromres.2006.06.015, PII S0049384806002350
    • Schöni R., Quehenberger P., Wu J. R., Wilmer M. Clinical evaluation of a new functional test for detection of activated protein C resistance (Pefakit APC-R Factor V Leiden) at two centers in Europe and the USA. Thromb Res: 2007; 119 1 17 26 (Pubitemid 44716212)
    • (2007) Thrombosis Research , vol.119 , Issue.1 , pp. 17-26
    • Schoni, R.1    Quehenberger, P.2    Wu, J.R.3    Wilmer, M.4
  • 160
    • 79960696897 scopus 로고    scopus 로고
    • Activated protein C resistance as measured by residual factor v after Russell's viper venom and activated protein C treatment analyzed as a continuous variable in multiple myeloma and normal controls
    • Zangari M., Berno T., Zhan F., Boucher K. M., Tricot G., Fink L. Activated protein C resistance as measured by residual factor V after Russell's viper venom and activated protein C treatment analyzed as a continuous variable in multiple myeloma and normal controls. Blood Coagul Fibrinolysis: 2011; 22 5 420 423
    • (2011) Blood Coagul Fibrinolysis , vol.22 , Issue.5 , pp. 420-423
    • Zangari, M.1    Berno, T.2    Zhan, F.3    Boucher, K.M.4    Tricot, G.5    Fink, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.