Platelet microparticle membranes have 50- to 100-fold higher specific procoagulant activity than activated platelets

Thrombosis and Haemostasis

Volumn 97, Issue 3, 2007, Pages 425-434

  Sinauridze, Elena I ^a   Kireev, Dmitry A ^a   Popenko, Nadezhda Y ^a   Pichugin, Aleksei V ^b   Panteleev, Mikhail A ^a   Krymskaya, Olga V ^a   Ataullakhanov, Fazoil I ^a,c,d  

^a NATIONAL RESEARCH CENTER FOR HEMATOLOGY   (Russian Federation)

^b INSTITUTE OF IMMUNOLOGY   (Russian Federation)

^c MOSCOW STATE UNIVERSITY   (Russian Federation)

^d CENTER FOR THEORETICAL PROBLEMS OF PHYSICOCHEMICAL PHARMACOLOGY   (Russian Federation)

Author keywords

CD 61; CD 62P; Factor X; Phosphatidylserine; Platelet; PMPs; Procoagulant activity; Spatial dynamics of coagulation; Thrombin generation

Indexed keywords

BLOOD CLOTTING FACTOR 10; CALCIMYCIN; CALCIUM IONOPHORE; CD61 ANTIGEN; LYMPHOCYTE SURFACE MARKER; PADGEM PROTEIN; PHOSPHATIDYLSERINE; PROCOAGULANT; THROMBIN;

ARTICLE; BLOOD CLOTTING; CONCENTRATION RESPONSE; CONTROLLED STUDY; EXPERIMENTAL MODEL; FLOW CYTOMETRY; GROWTH RATE; HEMOSTASIS; HUMAN; HUMAN CELL; LIGHT SCATTERING; LYMPHOCYTE DEPLETION; MOLECULAR DYNAMICS; PARTICLE SIZE; PLASMA; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; THROMBOCYTE ACTIVATION; THROMBOCYTE FUNCTION; THROMBOCYTE MEMBRANE;

BLOOD COAGULATION; BLOOD COAGULATION TESTS; BLOOD PLATELETS; CALCIMYCIN; CALCIUM; CYTOPLASMIC VESICLES; FACTOR X; FLOW CYTOMETRY; HUMANS; INTEGRIN BETA3; INTRACELLULAR MEMBRANES; IONOPHORES; LINEAR MODELS; P-SELECTIN; PARTICLE SIZE; PHOSPHATIDYLSERINES; PLATELET ACTIVATION; THROMBIN; TIME FACTORS;

EID: 33947322843     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH06-06-0313     Document Type: Article

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