Increased microparticle tissue factor activity in cancer patients with Venous Thromboembolism

Thrombosis Research

Volumn 125, Issue 6, 2010, Pages 511-512

  Manly, David A ^a   Wang, Jianguo ^a   Glover, Sam L ^a   Kasthuri, Raj ^a   Liebman, Howard A ^b   Key, Nigel S ^a   Mackman, Nigel ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Cancer; Microparticles; Tissue factor; Venous thrombosis

Indexed keywords

D DIMER; INTERLEUKIN 6; THROMBOPLASTIN; BIOLOGICAL MARKER; CHROMOGENIC SUBSTRATE;

ARTICLE; BILE DUCT CANCER; BILE DUCT CARCINOMA; BLADDER CANCER; BLOOD SAMPLING; BRAIN CANCER; CANCER PATIENT; CENTRIFUGATION; COLON CANCER; CONTROLLED STUDY; DEEP VEIN THROMBOSIS; HUMAN; KIDNEY CARCINOMA; LIVER CANCER; LUNG CANCER; LUNG EMBOLISM; LYMPHOMA; MAJOR CLINICAL STUDY; PANCREAS CANCER; PLATELET MICROPARTICLE; PRIORITY JOURNAL; RECTUM CANCER; RISK FACTOR; TESTIS CANCER; VENOUS THROMBOEMBOLISM; BLOOD; CASE CONTROL STUDY; CHEMISTRY; COLON TUMOR; COMPLICATION; DIAGNOSTIC USE; LUNG TUMOR; MEMBRANE MICROPARTICLE; NEOPLASM; PANCREAS TUMOR;

BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CELL-DERIVED MICROPARTICLES; CENTRIFUGATION; CHROMOGENIC COMPOUNDS; COLONIC NEOPLASMS; HUMANS; LUNG NEOPLASMS; NEOPLASMS; PANCREATIC NEOPLASMS; THROMBOPLASTIN; VENOUS THROMBOEMBOLISM;

EID: 77952548349     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2009.09.019     Document Type: Article

References (19)

1. Khorana A.A., Francis C.W., Culakova E., Kuderer N.M., and Lyman G.H. Thromboembolism is a leading cause of death in cancer patients receiving outpatient chemotherapy. Thromb Haemost 5 3 (2007) 632-634
2. Kroger K., Weiland D., Ose C., Neumann N., Weiss S., Hirsch C., Urbanski K., et al. Risk factors for venous thromboembolic events in cancer patients. Ann Oncol 17 2 (2006 Feb) 297-303
3. Ay C., Simanek R., Vormittag R., Dunkler D., Alguel G., Koder S., Kornek G., et al. High plasma levels of soluble P-selectin are predictive of venous thromboembolism in cancer patients: results from the Vienna Cancer and Thrombosis Study (CATS). Blood 112 7 (2008 Oct 1) 2703-2708
4. Cosmi B., Legnani C., Cini M., Guazzaloca G., and Palareti G. The role of D-dimer and residual venous obstruction in recurrence of venous thromboembolism after anticoagulation withdrawal in cancer patients. Haematologica 90 5 (2005 May) 713-715
5. Uno K., Homma S., Satoh T., Nakanishi K., Abe D., Matsumoto K., Oki A., et al. Tissue factor expression as a possible determinant of thromboembolism in ovarian cancer. Br J Cancer 96 2 (2007 Jan 29) 290-295
6. Chirinos J.A., Heresi G.A., Velasquez H., Jy W., Jimenez J.J., Ahn E., Horstman L.L., et al. Elevation of endothelial microparticles, platelets, and leukocyte activation in patients with venous thromboembolism. J Am Coll Cardio 45 9 (2005) 1467-1471
7. Mackman N., Tilley R.E., and Key N.S. Role of the extrinsic pathway of blood coagulation in hemostasis and thrombosis. Arteriosclerosis, Thrombosis, and Vascular Biology 27 (2007) 1687-1693
8. Bogdanov V.Y., Balasubramanian V., Hathcock J., Vele O., Lieb M., and Nemerson Y. Alternatively spliced human tissue factor: a circulating, soluble, thrombogenic protein. Nature Med 9 4 (2003) 458-462
9. Morel O., Toti F., Hugel B., Bakouboula B., Camoin-Jau L., Dignat-George F., and Freyssinet J.M. Procoagulant microparticles: disrupting the vascular homeostasis equation?. Arterioscler Thromb Vasc Biol 26 12 (2006) 2594-2604
10. Shet A.S., Aras O., Gupta K., Hass M.J., Rausch D.J., Saba N., Koopmeiners L., et al. Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes. Blood 102 7 (2003) 2678-2683
11. Aras O., Shet A., Bach R.R., Hysjulien J.L., Slungaard A., Hebbel R.P., Escolar G., et al. Induction of microparticle- and cell-associated intravascular tissue factor in human endotoxemia. Blood 103 (2004) 4545-4553
12. Tesselaar M.E., Romijn F.P., van der Linden I.K., Prins F.A., Bertina R.M., and Osanto S. Microparticle-associated tissue factor activity: a link between cancer and thrombosis?. J Thromb Haemost 5 3 (2007 Mar) 520-527
13. Hron G., Kollars M., Weber H., Sagaster V., Quehenberger P., Eichinger S., Kyrle P.A., et al. Tissue factor-positive microparticles: cellular origin and association with coagulation activation in patients with colorectal cancer. Thromb Haemost 97 1 (2007) 119-123
14. Khorana A.A., Francis C.W., Menzies K.E., Wang J.G., Hyrien O., Hathcock J., Mackman N., et al. Plasma tissue factor may be predictive of venous thromboembolism in pancreatic cancer. J Thromb Haemost 6 11 (2008 Nov) 1983-1985
15. Tesselaar M.E.T., Romijn F.P., Van Der Linden I.K., Bertina R.M., and Osanto S. Microparticle-associated tissue factor activity in cancer patients with or without thrombosis. J Throm Haemost 7 (2009) 1421-1423
16. White R.H., Chew H., and Wun T. Targeting patients for anticoagulant prophylaxis trials in patients with cancer: who is at highest risk?. Thromb Res 120 Suppl 2 (2007) S29-S40
17. Ay C., Vormittag R., Dunkler D., Simanek R., Chiriac A.L., Drach J., Quehenberger P., et al. D-dimer and prothrombin fragment 1 + 2 predict venous thromboembolism in patients with cancer: results from the Vienna cancer and thrombosis study. J Clin Oncol 27 (2009) 4124-4129
18. Berasain C., Castillo J., Perugorria M.J., Latasa M.U., Prieto J., and Avila M.A. Inflammation and liver cancer: new molecular links. Ann N Y Acad Sci 1155 (2009) 206-221
19. Ay C., Freyssinet J.-M., Sailer T., Vormittag R., and Pabinger I. Circulating procoagulant microparticles in patients with venous thromboembolism. Thromb Res 123 (2009) 724-726