Characterization of a myeloma patient with a life-threatening hemorrhagic diathesis: Presence of a lambda dimer protein inhibiting shear-induced platelet aggregation by binding to the A1 domain of von Willebrand factor

Thrombosis and Haemostasis

Volumn 93, Issue 5, 2005, Pages 889-896

  Shinagawa, Atsushi ^a   Kojima, Hiroshi ^b   Berndt, Michael C ^c   Kaneko, Shin ^b   Suzukawa, Kazumi ^b   Hasegawa, Yuichi ^b   Shigeta, Osamu ^b   Nagasawa, Toshiro ^b  

^a Hitachi General Hospital   (Japan)

^b UNIVERSITY OF TSUKUBA   (Japan)

^c MONASH UNIVERSITY   (Australia)

Author keywords

Coagulation inhibitors; Platelet physiology; Von Willebrand disease; von Willebrand factor

Indexed keywords

ADENOSINE DIPHOSPHATE; ADRENALIN; BOTROCETIN; COLLAGEN; DIMER; GLYCOPROTEIN IB ALPHA; IMMUNOGLOBULIN D; IMMUNOGLOBULIN LAMBDA CHAIN; LAMBDA DIMER PROTEIN; M PROTEIN; MONOCLONAL ANTIBODY; PROTEIN; RISTOCETIN; THROMBIN; UNCLASSIFIED DRUG; VON WILLEBRAND FACTOR;

ADULT; ARTICLE; BINDING SITE; BLEEDING TENDENCY; BLEEDING TIME; CASE REPORT; CONTROLLED STUDY; FEMALE; HEMOSTASIS; HUMAN; HUMAN CELL; MULTIPLE MYELOMA; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN IMMOBILIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; PUNCTURE; SHEAR STRESS; THROMBOCYTE AGGREGATION; VON WILLEBRAND DISEASE;

ADENOSINE DIPHOSPHATE; ADRENERGIC AGONISTS; ANTIBODIES, MONOCLONAL; ANTICOAGULANTS; BLOOD COAGULATION; BUFFERS; CELL ADHESION; COLLAGEN; CROTALID VENOMS; DIMERIZATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; EPINEPHRINE; FEMALE; FORMALDEHYDE; HEMATURIA; HEMOSTASIS; HUMANS; IMMUNOBLOTTING; IMMUNOGLOBULIN D; ISOELECTRIC POINT; MIDDLE AGED; MULTIPLE MYELOMA; PARTIAL THROMBOPLASTIN TIME; PLATELET ADHESIVENESS; PLATELET AGGREGATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTHROMBIN TIME; THROMBIN; TIME FACTORS; VON WILLEBRAND DISEASE; VON WILLEBRAND FACTOR;

EID: 18844374852     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH04-03-0193     Document Type: Article

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