-
1
-
-
0032748385
-
Antitumor activity of thalidomide in refractory multiple myeloma
-
Singhal S, Mehta J, Desikan R, Ayers D, Roberson P, Eddlemon P, Munshi N, Anaissie E, Wilson C, Dhodapkar M, Zeddis J, Barlogie B. Antitumor activity of thalidomide in refractory multiple myeloma. N Engl J Med 1999; 341: 1565-71.
-
(1999)
N. Engl. J. Med.
, vol.341
, pp. 1565-1571
-
-
Singhal, S.1
Mehta, J.2
Desikan, R.3
Ayers, D.4
Roberson, P.5
Eddlemon, P.6
Munshi, N.7
Anaissie, E.8
Wilson, C.9
Dhodapkar, M.10
Zeddis, J.11
Barlogie, B.12
-
2
-
-
0035469858
-
Increased risk of deep-vein thrombosis in patients with multiple myeloma receiving thalidomide and chemotherapy
-
Zangari M, Anaissie E, Barlogie B, Badros A, Desikan R, Gopal AV, Morris C, Toor A, Siegel E, Fink L, Tricot G. Increased risk of deep-vein thrombosis in patients with multiple myeloma receiving thalidomide and chemotherapy. Blood 2001; 98: 1614-5.
-
(2001)
Blood
, vol.98
, pp. 1614-1615
-
-
Zangari, M.1
Anaissie, E.2
Barlogie, B.3
Badros, A.4
Desikan, R.5
Gopal, A.V.6
Morris, C.7
Toor, A.8
Siegel, E.9
Fink, L.10
Tricot, G.11
-
3
-
-
0036526384
-
Activated protein C resistance in the absence of factor V Leiden mutation is a common finding in multiple myeloma and is associated with an increased risk of thrombotic complications
-
Zangari M, Saghafifar F, Anaissie E, Badros A, Desikan R, Fassas A, Mehta P, Morris C, Toor A, Whitfield D, Siegel E, Barlogie B, Fink L, Tricot G. Activated protein C resistance in the absence of factor V Leiden mutation is a common finding in multiple myeloma and is associated with an increased risk of thrombotic complications. Blood Coagul Fibrinolysis 2002; 13: 187-92.
-
(2002)
Blood Coagul. Fibrinolysis
, vol.13
, pp. 187-192
-
-
Zangari, M.1
Saghafifar, F.2
Anaissie, E.3
Badros, A.4
Desikan, R.5
Fassas, A.6
Mehta, P.7
Morris, C.8
Toor, A.9
Whitfield, D.10
Siegel, E.11
Barlogie, B.12
Fink, L.13
Tricot, G.14
-
4
-
-
0037108279
-
A high rate of venous thromboembolism in a multi-institutional phase II trial of weekly intravenous gemcitabine with continuous infusion fluorouracil and daily thalidomide in patients with metastatic renal cell carcinoma
-
Desai AA, Vogelzang NJ, Rini BI, Ansari R, Krauss S, Stadler WM. A high rate of venous thromboembolism in a multi-institutional phase II trial of weekly intravenous gemcitabine with continuous infusion fluorouracil and daily thalidomide in patients with metastatic renal cell carcinoma. Cancer 2002; 95: 1629-36.
-
(2002)
Cancer
, vol.95
, pp. 1629-1636
-
-
Desai, A.A.1
Vogelzang, N.J.2
Rini, B.I.3
Ansari, R.4
Krauss, S.5
Stadler, W.M.6
-
5
-
-
0037087585
-
Dose-finding and pharmacokinetic study of cisplatin, gemcitabine, and SU5416 in patients with solid tumors
-
Kuenen BC, Rosen L, Smit EF, Parson MR, Levi M, Ruijter R, et al.. Dose-finding and pharmacokinetic study of cisplatin, gemcitabine, and SU5416 in patients with solid tumors. J Clin Oncol 2002; 20: 1657-67.
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 1657-1667
-
-
Kuenen, B.C.1
Rosen, L.2
Smit, E.F.3
Parson, M.R.4
Levi, M.5
Ruijter, R.6
-
6
-
-
0034949453
-
Anticancer drugs induce necrosis of human endothelial cells involving both oncosis and apoptosis
-
Mailloux A, Grenet K, Bruneel A, Beneteau-Burnat B, Vaubourdolle M, Baudin B. Anticancer drugs induce necrosis of human endothelial cells involving both oncosis and apoptosis. Eur J Cell Biol 2001; 80: 442-9.
-
(2001)
Eur. J. Cell Biol.
, vol.80
, pp. 442-449
-
-
Mailloux, A.1
Grenet, K.2
Bruneel, A.3
Beneteau-Burnat, B.4
Vaubourdolle, M.5
Baudin, B.6
-
7
-
-
0034721770
-
Doxorubicin-induced apoptosis in endothelial cells and cardiomyocytes is ameliorated by nitrone spin traps and ebselen. Role of reactive oxygen and nitrogen species
-
Kotamraju S, Konorev EA, Joseph J, Kalyanaraman B. Doxorubicin-induced apoptosis in endothelial cells and cardiomyocytes is ameliorated by nitrone spin traps and ebselen. Role of reactive oxygen and nitrogen species. J Biol Chem 2000; 275: 33585-92.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 33585-33592
-
-
Kotamraju, S.1
Konorev, E.A.2
Joseph, J.3
Kalyanaraman, B.4
-
8
-
-
0037192824
-
Doxorubicin induces apoptosis and CD95 gene expression in human primary endothelial cells through a p53-dependent mechanism
-
Lorenzo E, Ruiz-Ruiz C, Quesada AJ, Hernandez G, Rodriguez A, Lopez-Rivas A, Redondo JM. Doxorubicin induces apoptosis and CD95 gene expression in human primary endothelial cells through a p53-dependent mechanism. J Biol Chem 2002; 277: 10883-92.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 10883-10892
-
-
Lorenzo, E.1
Ruiz-Ruiz, C.2
Quesada, A.J.3
Hernandez, G.4
Rodriguez, A.5
Lopez-Rivas, A.6
Redondo, J.M.7
-
9
-
-
0034331194
-
Thalidomide and its analogs overcome drug resistance of human multiple myeloma cells to conventional therapy
-
Hideshima T, Chauhan D, Shima Y, Raje N, Davies FE, Tai YT, Treon SP, Lin B, Schlossman RL, Richardson P, Muller G, Stirling DI, Anderson KC. Thalidomide and its analogs overcome drug resistance of human multiple myeloma cells to conventional therapy. Blood 2000; 96: 2943-50.
-
(2000)
Blood
, vol.96
, pp. 2943-2950
-
-
Hideshima, T.1
Chauhan, D.2
Shima, Y.3
Raje, N.4
Davies, F.E.5
Tai, Y.T.6
Treon, S.P.7
Lin, B.8
Schlossman, R.L.9
Richardson, P.10
Muller, G.11
Stirling, D.I.12
Anderson, K.C.13
-
10
-
-
0037097595
-
Apoptotic signaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells: Therapeutic implications
-
Mitsiades N, Mitsiades CS, Poulaki V, Chauhan D, Richardson PG, Hideshima T, Munshi NC, Treon SP, Anderson KC. Apoptotic signaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells: therapeutic implications. Blood 2002; 99: 4525-30.
-
(2002)
Blood
, vol.99
, pp. 4525-4530
-
-
Mitsiades, N.1
Mitsiades, C.S.2
Poulaki, V.3
Chauhan, D.4
Richardson, P.G.5
Hideshima, T.6
Munshi, N.C.7
Treon, S.P.8
Anderson, K.C.9
-
11
-
-
0033559805
-
Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin
-
Kahn ML, Nakanishi-Matsui M, Shapiro MJ, Ishihara H, Coughlin SR. Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin. J Clin Invest 1999; 103: 879-87.
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 879-887
-
-
Kahn, M.L.1
Nakanishi-Matsui, M.2
Shapiro, M.J.3
Ishihara, H.4
Coughlin, S.R.5
-
12
-
-
0035979691
-
A role for thrombin receptor signaling in endothelial cells during embryonic development
-
Griffin CT, Srinivasan Y, Zheng YW, Huang W, Coughlin SR. A role for thrombin receptor signaling in endothelial cells during embryonic development. Science 2001; 293: 1666-70.
-
(2001)
Science
, vol.293
, pp. 1666-1670
-
-
Griffin, C.T.1
Srinivasan, Y.2
Zheng, Y.W.3
Huang, W.4
Coughlin, S.R.5
-
13
-
-
0034778721
-
Role and regulation of activation of caspases in cisplatin-induced injury to renal tubular epithelial cells
-
Kaushal GP, Kaushal V, Hong X, Shah SV. Role and regulation of activation of caspases in cisplatin-induced injury to renal tubular epithelial cells. Kidney Int 2001; 60: 1726-36.
-
(2001)
Kidney Int.
, vol.60
, pp. 1726-1736
-
-
Kaushal, G.P.1
Kaushal, V.2
Hong, X.3
Shah, S.V.4
-
14
-
-
0032724653
-
Caspase-3 is the primary activator of apoptotic DNA fragmentation via DNA fragmentation factor-45/inhibitor of caspase-activated DNase inactivation
-
Wolf BB, Schuler M, Echeverri F, Green DR. Caspase-3 is the primary activator of apoptotic DNA fragmentation via DNA fragmentation factor-45/inhibitor of caspase-activated DNase inactivation. J Biol Chem 1999; 274: 30651-6.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 30651-30656
-
-
Wolf, B.B.1
Schuler, M.2
Echeverri, F.3
Green, D.R.4
-
15
-
-
0026702323
-
Modulation of tissue factor on human monocytes by cisplatin and adriamycin
-
Walsh J, Wheeler HR, Geczy CL. Modulation of tissue factor on human monocytes by cisplatin and adriamycin. Br J Haematol 1992; 81: 480-8.
-
(1992)
Br. J. Haematol.
, vol.81
, pp. 480-488
-
-
Walsh, J.1
Wheeler, H.R.2
Geczy, C.L.3
-
16
-
-
0024990653
-
Induction of macrophage procoagulant expression by cisplatin, daunorubicin and doxorubicin
-
Wheeler HR, Geczy CL. Induction of macrophage procoagulant expression by cisplatin, daunorubicin and doxorubicin. Int J Cancer 1990; 46: 626-32.
-
(1990)
Int. J. Cancer
, vol.46
, pp. 626-632
-
-
Wheeler, H.R.1
Geczy, C.L.2
-
17
-
-
2642668464
-
Tissue-factor expression in human non-small-cell lung carcinoma measured by immunohistochemistry: Correlation between tissue factor and angiogenesis
-
Koomagi R, Volm M. Tissue-factor expression in human non-small-cell lung carcinoma measured by immunohistochemistry: correlation between tissue factor and angiogenesis. Int J Cancer 1998; 79: 19-22.
-
(1998)
Int. J. Cancer
, vol.79
, pp. 19-22
-
-
Koomagi, R.1
Volm, M.2
-
18
-
-
0034053127
-
The protease thrombin is an endogenous mediator of hippocampal neuroprotection against ischemia at low concentrations but causes degeneration at high concentrations
-
Striggow F, Riek M, Breder J, Henrich-Noack P, Reymann KG, Reiser G. The protease thrombin is an endogenous mediator of hippocampal neuroprotection against ischemia at low concentrations but causes degeneration at high concentrations. Proc Natl Acad Sci USA 2000; 97: 2264-9.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 2264-2269
-
-
Striggow, F.1
Riek, M.2
Breder, J.3
Henrich-Noack, P.4
Reymann, K.G.5
Reiser, G.6
-
19
-
-
0033545627
-
A protective role for protease-activated receptors in the airways
-
Cocks TM, Fong B, Chow JM, Anderson GP, Frauman AG, Goldie RG, Henry PJ, Carr MJ, Hamilton JR, Moffatt JD. A protective role for protease-activated receptors in the airways. Nature 1999; 398 156-60.
-
(1999)
Nature
, vol.398
, pp. 156-160
-
-
Cocks, T.M.1
Fong, B.2
Chow, J.M.3
Anderson, G.P.4
Frauman, A.G.5
Goldie, R.G.6
Henry, P.J.7
Carr, M.J.8
Hamilton, J.R.9
Moffatt, J.D.10
-
20
-
-
0034933683
-
Mechanistic coupling of protease signaling and initiation of coagulation by tissue factor
-
Riewald M, Ruf W. Mechanistic coupling of protease signaling and initiation of coagulation by tissue factor. Proc Natl Acad Sci USA 2001; 98: 7742-7.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 7742-7747
-
-
Riewald, M.1
Ruf, W.2
-
21
-
-
0036549755
-
Coagulation cascade proteases and tissue fibrosis
-
Chambers RC, Laurent GJ. Coagulation cascade proteases and tissue fibrosis. Biochem Soc Trans 2002; 30: 194-200.
-
(2002)
Biochem. Soc. Trans.
, vol.30
, pp. 194-200
-
-
Chambers, R.C.1
Laurent, G.J.2
-
22
-
-
0033532076
-
Thrombin induces proteinase-activated receptor-1 gene expression in endothelial cells via activation of Gi-linked Ras/mitogen-activated protein kinase pathway
-
Ellis CA, Malik AB, Gilchrist A, Hamm H, Sandoval R, Voyno-Yasenetskaya T, Tiruppathi C. Thrombin induces proteinase-activated receptor-1 gene expression in endothelial cells via activation of Gi-linked Ras/mitogen-activated protein kinase pathway. J Biol Chem 1999; 274: 13718-27.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 13718-13727
-
-
Ellis, C.A.1
Malik, A.B.2
Gilchrist, A.3
Hamm, H.4
Sandoval, R.5
Voyno-Yasenetskaya, T.6
Tiruppathi, C.7
-
23
-
-
0034581513
-
Thrombin regulates the expression of proangiogenic cytokines via proteolytic activation of protease-activated receptor-1
-
Naldini A, Carney DH, Pucci A, Pasquali A, Carraro F. Thrombin regulates the expression of proangiogenic cytokines via proteolytic activation of protease-activated receptor-1. Gen Pharmacol 2000; 35: 255-9.
-
(2000)
Gen. Pharmacol.
, vol.35
, pp. 255-259
-
-
Naldini, A.1
Carney, D.H.2
Pucci, A.3
Pasquali, A.4
Carraro, F.5
-
24
-
-
0034142240
-
Activation of the small GTPases, rac and cdc42, after ligation of the platelet PAR-1 receptor
-
Azim AC, Barkalow K, Chou J, Hartwig JH. Activation of the small GTPases, rac and cdc42, after ligation of the platelet PAR-1 receptor. Blood 2000; 95: 959-64.
-
(2000)
Blood
, vol.95
, pp. 959-964
-
-
Azim, A.C.1
Barkalow, K.2
Chou, J.3
Hartwig, J.H.4
-
25
-
-
0037530506
-
Potential role of platelets in endothelial damage observed during treatment with cisplatin, gemcitabine, and the angiogenesis inhibitor SU5416
-
Kuenen BC, Levi M, Meijers JC, van Hinsbergh VW, Berkhof J, Kakkar AK, Hoekman K, Pinedo HM. Potential role of platelets in endothelial damage observed during treatment with cisplatin, gemcitabine, and the angiogenesis inhibitor SU5416. J Clin Oncol 2003; 21: 2192-8.
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 2192-2198
-
-
Kuenen, B.C.1
Levi, M.2
Meijers, J.C.3
van Hinsbergh, V.W.4
Berkhof, J.5
Kakkar, A.K.6
Hoekman, K.7
Pinedo, H.M.8
-
26
-
-
0036738403
-
Analysis of coagulation cascade and endothelial cell activation during inhibition of vascular endothelial growth factor/vascular endothelial growth factor receptor pathway in cancer patients
-
Kuenen BC, Levi M, Meijers JC, Kakkar AK, van Hinsbergh VW, Kostense PJ, et al. Analysis of coagulation cascade and endothelial cell activation during inhibition of vascular endothelial growth factor/vascular endothelial growth factor receptor pathway in cancer patients. Arterioscler Thromb Vasc Biol 2002; 22: 1500-5.
-
(2002)
Arterioscler. Thromb. Vasc. Biol.
, vol.22
, pp. 1500-1505
-
-
Kuenen, B.C.1
Levi, M.2
Meijers, J.C.3
Kakkar, A.K.4
van Hinsbergh, V.W.5
Kostense, P.J.6
-
27
-
-
0032941869
-
Actions of heparin that may affect the malignant process
-
Engelberg H. Actions of heparin that may affect the malignant process. Cancer 1999; 85: 257-72.
-
(1999)
Cancer
, vol.85
, pp. 257-272
-
-
Engelberg, H.1
-
29
-
-
0035715543
-
Inhibition of human angiogenesis with heparin and hydrocortisone
-
Jung SP, Siegrist B, Wade MR, Anthony CT, Woltering EA. Inhibition of human angiogenesis with heparin and hydrocortisone. Angiogenesis 2001; 4: 175-86.
-
(2001)
Angiogenesis
, vol.4
, pp. 175-186
-
-
Jung, S.P.1
Siegrist, B.2
Wade, M.R.3
Anthony, C.T.4
Woltering, E.A.5
-
30
-
-
0033578910
-
Antiangiogenic activity of the cleaved conformation of the serpin antithrombin
-
O'Reilly MS, Pirie-Shepherd S, Lane WS, Folkman J. Antiangiogenic activity of the cleaved conformation of the serpin antithrombin. Science 1999; 285: 1926-8.
-
(1999)
Science
, vol.285
, pp. 1926-1928
-
-
O'Reilly, M.S.1
Pirie-Shepherd, S.2
Lane, W.S.3
Folkman, J.4
-
31
-
-
0028285494
-
Evidence that nitric oxide is an endogenous antiangiogenic mediator
-
Pipili-Synetos E, Sakkoula E, Haralabopoulos G, Andriopoulou P, Peristeris P, Maragoudakis ME. Evidence that nitric oxide is an endogenous antiangiogenic mediator. Br J Pharmacol 1994; 111: 894-902.
-
(1994)
Br. J. Pharmacol.
, vol.111
, pp. 894-902
-
-
Pipili-Synetos, E.1
Sakkoula, E.2
Haralabopoulos, G.3
Andriopoulou, P.4
Peristeris, P.5
Maragoudakis, M.E.6
-
33
-
-
0037053406
-
Transferrin receptor-dependent iron uptake is responsible for doxorubicin-mediated apoptosis in endothelial cells: Role of oxidant-induced iron signaling in apoptosis
-
Kotamraju S, Chitambar CR, Kalivendi SV, Joseph J, Kalyanaraman B. Transferrin receptor-dependent iron uptake is responsible for doxorubicin-mediated apoptosis in endothelial cells: role of oxidant-induced iron signaling in apoptosis. J Biol Chem 2002; 277: 17179-87.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 17179-17187
-
-
Kotamraju, S.1
Chitambar, C.R.2
Kalivendi, S.V.3
Joseph, J.4
Kalyanaraman, B.5
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