Neuronal activity and secreted amyloid β lead to altered amyloid β precursor protein and presenilin 1 interactions

Neurobiology of Disease

Volumn 50, Issue 1, 2013, Pages 127-134

  Li, Xuejing ^a   Uemura, Kengo ^b   Hashimoto, Tadafumi ^a   Nasser Ghodsi, Navine ^a   Arimon, Muriel ^a   Lill, Christina M ^c   Palazzolo, Isabella ^a   Krainc, Dimitri ^a   Hyman, Bradley T ^a   Berezovska, Oksana ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b KYOTO UNIVERSITY   (Japan)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Alzheimer's disease; Amyloid precursor protein; FLIM (fluorescence lifetime imaging microscopy); Neuronal activity; Presenilin 1

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; PRESENILIN 1;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EMBRYO; FLUORESCENCE MICROSCOPY; MOUSE; NERVE CELL CULTURE; NERVOUS SYSTEM FUNCTION; NEURONAL ACTIVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; REGULATORY MECHANISM;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BLOTTING, WESTERN; FEEDBACK, PHYSIOLOGICAL; HUMANS; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; MICE; MICE, TRANSGENIC; NEURONS; PRESENILIN-1;

EID: 84868464841     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2012.10.002     Document Type: Article

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