-
3
-
-
0036359548
-
Hypoxia - A key regulatory factor in tumour growth
-
A.L. Harris Hypoxia - a key regulatory factor in tumour growth Nat Rev Cancer 2 2002 38 47
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 38-47
-
-
Harris, A.L.1
-
4
-
-
84960987950
-
The concentration of oxygen dissolved in tissues at time of irradiation as a factor in radiotherapy
-
L. Gray, A. Conger, M. Ebert, S. Hornsey, and O.C. Scott The concentration of oxygen dissolved in tissues at time of irradiation as a factor in radiotherapy Br J Radiol 26 1953 638 648
-
(1953)
Br J Radiol
, vol.26
, pp. 638-648
-
-
Gray, L.1
Conger, A.2
Ebert, M.3
Hornsey, S.4
Scott, O.C.5
-
6
-
-
0026711036
-
Enhancement of tumor radiosensitivity and reduced hypoxia-dependent binding of a 2-nitroimidazole with normobaric oxygen and carbogen: A therapeutic comparison with skin and kidneys
-
A. Rojas, M.C. Joiner, R.J. Hodgkiss, U. Carl, E. Kjellen, and G.D. Wilson Enhancement of tumor radiosensitivity and reduced hypoxia-dependent binding of a 2-nitroimidazole with normobaric oxygen and carbogen: a therapeutic comparison with skin and kidneys Int J Radiat Oncol Biol Phys 23 1992 361 366
-
(1992)
Int J Radiat Oncol Biol Phys
, vol.23
, pp. 361-366
-
-
Rojas, A.1
Joiner, M.C.2
Hodgkiss, R.J.3
Carl, U.4
Kjellen, E.5
Wilson, G.D.6
-
7
-
-
33751543273
-
Hypoxia: Importance in tumor biology, noninvasive measurement by imaging, and value of its measurement in the management of cancer therapy
-
J.L. Tatum, G.J. Kelloff, and R.J. Gillies Hypoxia: importance in tumor biology, noninvasive measurement by imaging, and value of its measurement in the management of cancer therapy Int J Radiat Biol 82 2006 699 757
-
(2006)
Int J Radiat Biol
, vol.82
, pp. 699-757
-
-
Tatum, J.L.1
Kelloff, G.J.2
Gillies, R.J.3
-
8
-
-
40249089741
-
Provascular strategy: Targeting functional adaptations of mature blood vessels in tumors to selectively influence the tumor vascular reactivity and improve cancer treatment
-
P. Sonveaux Provascular strategy: targeting functional adaptations of mature blood vessels in tumors to selectively influence the tumor vascular reactivity and improve cancer treatment Radiother Oncol 86 2008 300 313
-
(2008)
Radiother Oncol
, vol.86
, pp. 300-313
-
-
Sonveaux, P.1
-
9
-
-
78650671148
-
Surrogate MR markers of response to chemo- or radiotherapy in association with co-treatments: A retrospective analysis of multi-modal studies
-
B.F. Jordan, and B. Gallez Surrogate MR markers of response to chemo- or radiotherapy in association with co-treatments: a retrospective analysis of multi-modal studies Contrast Media Mol Imaging 5 2010 323 332
-
(2010)
Contrast Media Mol Imaging
, vol.5
, pp. 323-332
-
-
Jordan, B.F.1
Gallez, B.2
-
10
-
-
33749608983
-
Preclinical safety and antitumor efficacy of insulin combined with irradiation
-
B.F. Jordan, N. Beghein, N. Crokart, C. Baudelet, V. Grégoire, and B. Gallez Preclinical safety and antitumor efficacy of insulin combined with irradiation Radiother Oncol 81 2006 112 117
-
(2006)
Radiother Oncol
, vol.81
, pp. 112-117
-
-
Jordan, B.F.1
Beghein, N.2
Crokart, N.3
Baudelet, C.4
Grégoire, V.5
Gallez, B.6
-
11
-
-
0035266246
-
The farnesyltransferase inhibitor L744, 832 reduces hypoxia in tumors expressing activated H-ras
-
E. Cohen-Jonathan, S.M. Evans, and C.J. Koch The farnesyltransferase inhibitor L744, 832 reduces hypoxia in tumors expressing activated H-ras Cancer Res 61 2001 2289 2293
-
(2001)
Cancer Res
, vol.61
, pp. 2289-2293
-
-
Cohen-Jonathan, E.1
Evans, S.M.2
Koch, C.J.3
-
12
-
-
0142178057
-
Farnesyltransferase inhibitors as radiation sensitizers
-
T.B. Brunner, A.K. Gupta, and Y. Shi Farnesyltransferase inhibitors as radiation sensitizers Int J Radiat Biol 79 2003 569 576
-
(2003)
Int J Radiat Biol
, vol.79
, pp. 569-576
-
-
Brunner, T.B.1
Gupta, A.K.2
Shi, Y.3
-
13
-
-
77954235111
-
Targeting the Mitogen-Activated Protein Kinase pathway: Physiological feedback and drug response
-
C.A. Pratilas, and D.B. Solit Targeting the Mitogen-Activated Protein Kinase pathway: physiological feedback and drug response Clin Cancer Res 16 2010 3329 3334
-
(2010)
Clin Cancer Res
, vol.16
, pp. 3329-3334
-
-
Pratilas, C.A.1
Solit, D.B.2
-
14
-
-
4944249117
-
BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
-
S.M. Wilhelm, C. Carter, and L. Tang BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis Cancer Res 64 2004 7099 7109
-
(2004)
Cancer Res
, vol.64
, pp. 7099-7109
-
-
Wilhelm, S.M.1
Carter, C.2
Tang, L.3
-
15
-
-
10344258041
-
Targeting the mitogen-activated protein kinase cascade to treat cancer
-
J.S. Sebolt-Leopold, and R. Herrera Targeting the mitogen-activated protein kinase cascade to treat cancer Nat Rev Cancer 4 2004 937 947
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 937-947
-
-
Sebolt-Leopold, J.S.1
Herrera, R.2
-
16
-
-
34447500409
-
2 measurements by electron paramagnetic resonance oximetry: Current status and future potential for experimental and clinical studies
-
2 measurements by electron paramagnetic resonance oximetry: current status and future potential for experimental and clinical studies Antioxid Redox Signal 9 2007 1169 1182
-
(2007)
Antioxid Redox Signal
, vol.9
, pp. 1169-1182
-
-
Khan, N.1
Williams, B.B.2
Hou, H.3
Li, H.4
Swartz, H.M.5
-
17
-
-
0031842960
-
The measurement of oxygen in vivo using EPR techniques
-
H.M. Swartz, and R.B. Clarkson The measurement of oxygen in vivo using EPR techniques Phys Med Biol 43 1998 1957 1975
-
(1998)
Phys Med Biol
, vol.43
, pp. 1957-1975
-
-
Swartz, H.M.1
Clarkson, R.B.2
-
18
-
-
0013874264
-
A new transplantable mouse liver tumor of spontaneous origin
-
H.S. Taper, G.W. Woolley, M.N. Teller, and M.P. Lardis A new transplantable mouse liver tumor of spontaneous origin Cancer Res 26 1966 143 148
-
(1966)
Cancer Res
, vol.26
, pp. 143-148
-
-
Taper, H.S.1
Woolley, G.W.2
Teller, M.N.3
Lardis, M.P.4
-
19
-
-
0022411804
-
Metastatic properties of murine sarcomas and carcinomas. I. Positive correlation with lung colonization and lack of correlation with s.c. tumor take
-
J.P. Volpe, N. Hunter, I. Basic, and L. Milas Metastatic properties of murine sarcomas and carcinomas. I. Positive correlation with lung colonization and lack of correlation with s.c. tumor take Clin Exp Metastasis 3 1985 281 294
-
(1985)
Clin Exp Metastasis
, vol.3
, pp. 281-294
-
-
Volpe, J.P.1
Hunter, N.2
Basic, I.3
Milas, L.4
-
20
-
-
4644283094
-
Assessment of tumor oxygenation by electron paramagnetic resonance. principles and applications
-
B. Gallez, C. Baudelet, and B.F. Jordan Assessment of tumor oxygenation by electron paramagnetic resonance. principles and applications NMR Biomed 17 2004 240 262
-
(2004)
NMR Biomed
, vol.17
, pp. 240-262
-
-
Gallez, B.1
Baudelet, C.2
Jordan, B.F.3
-
21
-
-
0032850849
-
Pharmacological modifications of the partial pressure of oxygen in murine tumors: Evaluation using in vivo EPR oximetry
-
B. Gallez, B.F. Jordan, C. Baudelet, and P.D. Misson Pharmacological modifications of the partial pressure of oxygen in murine tumors: evaluation using in vivo EPR oximetry Magn Reson Med 42 1999 627 630
-
(1999)
Magn Reson Med
, vol.42
, pp. 627-630
-
-
Gallez, B.1
Jordan, B.F.2
Baudelet, C.3
Misson, P.D.4
-
22
-
-
0344719191
-
Tumor blood flow modifying effect of electrochemotherapy with bleomycin
-
G. Sersa, M. Cemazar, D. Miklavcic, and D.J. Chaplin Tumor blood flow modifying effect of electrochemotherapy with bleomycin Anticancer Res 19 1999 4017 4022
-
(1999)
Anticancer Res
, vol.19
, pp. 4017-4022
-
-
Sersa, G.1
Cemazar, M.2
Miklavcic, D.3
Chaplin, D.J.4
-
23
-
-
0037096740
-
Insulin increases the sensitivity of tumors to irradiation: Involvement of an increase in tumor oxygenation mediated by a nitric oxide-dependent decrease of the tumor cells oxygen consumption
-
B.F. Jordan, V. Gregoire, and R.J. Demeure Insulin increases the sensitivity of tumors to irradiation: involvement of an increase in tumor oxygenation mediated by a nitric oxide-dependent decrease of the tumor cells oxygen consumption Cancer Res 62 2002 3555 3561
-
(2002)
Cancer Res
, vol.62
, pp. 3555-3561
-
-
Jordan, B.F.1
Gregoire, V.2
Demeure, R.J.3
-
24
-
-
0028950576
-
The effects of endotoxin on oxygen consumption of various cell types in vitro: An EPR oximetry study
-
P.E. James, S.K. Jackson, O.Y. Grinberg, and H.M. Swartz The effects of endotoxin on oxygen consumption of various cell types in vitro: an EPR oximetry study Free Radic Biol Med 18 1995 641 647
-
(1995)
Free Radic Biol Med
, vol.18
, pp. 641-647
-
-
James, P.E.1
Jackson, S.K.2
Grinberg, O.Y.3
Swartz, H.M.4
-
25
-
-
0014481378
-
Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues
-
F. Tietze Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues Anal Biochem 27 1969 502 522
-
(1969)
Anal Biochem
, vol.27
, pp. 502-522
-
-
Tietze, F.1
-
26
-
-
0019167355
-
Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine
-
O.W. Griffith Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine Anal Biochem 106 1980 207 212
-
(1980)
Anal Biochem
, vol.106
, pp. 207-212
-
-
Griffith, O.W.1
-
28
-
-
33846865354
-
Glucocorticoids modulate tumor radiation response through a decrease in tumor oxygen consumption
-
N. Crokart, B.F. Jordan, and C. Baudelet Glucocorticoids modulate tumor radiation response through a decrease in tumor oxygen consumption Clin Cancer Res 13 2007 630 635
-
(2007)
Clin Cancer Res
, vol.13
, pp. 630-635
-
-
Crokart, N.1
Jordan, B.F.2
Baudelet, C.3
-
29
-
-
33750296338
-
Mechanism of reoxygenation after antiangiogenic therapy using SU5416 and its importance for guiding combined antitumor therapy
-
R. Ansiaux, C. Baudelet, and B.F. Jordan Mechanism of reoxygenation after antiangiogenic therapy using SU5416 and its importance for guiding combined antitumor therapy Cancer Res 66 2006 9698 9704
-
(2006)
Cancer Res
, vol.66
, pp. 9698-9704
-
-
Ansiaux, R.1
Baudelet, C.2
Jordan, B.F.3
-
30
-
-
35148842941
-
Cell cycle dependent and schedule-dependent antitumor effects of sorafenib combined with radiation
-
J.P. Plastaras, S.H. Kim, and Y.Y. Liu Cell cycle dependent and schedule-dependent antitumor effects of sorafenib combined with radiation Cancer Res 67 2007 9443 9454
-
(2007)
Cancer Res
, vol.67
, pp. 9443-9454
-
-
Plastaras, J.P.1
Kim, S.H.2
Liu, Y.Y.3
-
31
-
-
77955904732
-
Sorafenib and radiation: A promising combination in colorectal cancer
-
A.W. Suen, S. Galoforo, and B. Marples Sorafenib and radiation: a promising combination in colorectal cancer Int J Radiat Oncol Biol Phys 78 2010 213 220
-
(2010)
Int J Radiat Oncol Biol Phys
, vol.78
, pp. 213-220
-
-
Suen, A.W.1
Galoforo, S.2
Marples, B.3
-
32
-
-
0029069833
-
Influence of an anti-angiogenic treatment on 9L gliosarcoma: Oxygenation and response to cytotoxic therapy
-
B.A. Teicher, S.A. Holden, and G. Ara Influence of an anti-angiogenic treatment on 9L gliosarcoma: oxygenation and response to cytotoxic therapy Int J Cancer 61 1995 732 737
-
(1995)
Int J Cancer
, vol.61
, pp. 732-737
-
-
Teicher, B.A.1
Holden, S.A.2
Ara, G.3
-
33
-
-
84982729034
-
Anti-angiogenic agents can increase tumor oxygenation and response to radiation therapy
-
B.A. Teicher, N. Dupuis, and T. Kusomoto Anti-angiogenic agents can increase tumor oxygenation and response to radiation therapy Radiat Oncol Investig 2 1994 269 276
-
(1994)
Radiat Oncol Investig
, vol.2
, pp. 269-276
-
-
Teicher, B.A.1
Dupuis, N.2
Kusomoto, T.3
-
34
-
-
0034306974
-
Anti-vascular endothelial growth factor treatment augments tumor radiation response under normoxic or hypoxic conditions
-
C. Lee, M. Heijn, and E. Di Tomaso Anti-vascular endothelial growth factor treatment augments tumor radiation response under normoxic or hypoxic conditions Cancer Res 60 2000 5565 5570
-
(2000)
Cancer Res
, vol.60
, pp. 5565-5570
-
-
Lee, C.1
Heijn, M.2
Di Tomaso, E.3
-
35
-
-
33750296338
-
Mechanism of reoxygenation after antiangiogenic therapy using SU5416 and its importance for guiding combined antitumor therapy
-
R. Ansiaux, C. Baudelet, and B.F. Jordan Mechanism of reoxygenation after antiangiogenic therapy using SU5416 and its importance for guiding combined antitumor therapy Cancer Res 66 2006 9698 9704
-
(2006)
Cancer Res
, vol.66
, pp. 9698-9704
-
-
Ansiaux, R.1
Baudelet, C.2
Jordan, B.F.3
-
36
-
-
70449704420
-
Decrease in tumor cell oxygen consumption after treatment with vandetanib (ZACTIMA; ZD6474) and its effect on response to radiotherapy
-
R. Ansiaux, J. Dewever, V. Gregoire, O. Feron, B.F. Jordan, and B. Gallez Decrease in tumor cell oxygen consumption after treatment with vandetanib (ZACTIMA; ZD6474) and its effect on response to radiotherapy Radiat Res 172 2009 584 591
-
(2009)
Radiat Res
, vol.172
, pp. 584-591
-
-
Ansiaux, R.1
Dewever, J.2
Gregoire, V.3
Feron, O.4
Jordan, B.F.5
Gallez, B.6
-
37
-
-
0031742171
-
MIBG inhibits respiration: Potential for radio- and hyperthermic sensitization
-
J.E. Biaglow, Y. Manevich, and D. Leeper MIBG inhibits respiration: potential for radio- and hyperthermic sensitization Int J Radiat Oncol Biol Phys 1 1998 871 876
-
(1998)
Int J Radiat Oncol Biol Phys
, vol.1
, pp. 871-876
-
-
Biaglow, J.E.1
Manevich, Y.2
Leeper, D.3
-
38
-
-
78650763353
-
Intracellular GSH depletion triggered mitochondrial bax translocation to accomplish resveratrol-induced apoptosis in the U937 cell line
-
P. Guha, A. Dey, R. Sen, M. Chatterjee, S. Chattopadhyay, and S.K. Bandyopadhyay Intracellular GSH depletion triggered mitochondrial bax translocation to accomplish resveratrol-induced apoptosis in the U937 cell line J Pharmacol Exp Ther 336 2011 206 214
-
(2011)
J Pharmacol Exp Ther
, vol.336
, pp. 206-214
-
-
Guha, P.1
Dey, A.2
Sen, R.3
Chatterjee, M.4
Chattopadhyay, S.5
Bandyopadhyay, S.K.6
-
39
-
-
73549094006
-
Sorafenib induces preferential apoptotic killing of a drug- and radio-resistant Hep G2 cells through a mitochondria-dependent oxidative stress mechanism
-
J.F. Chiou, C.J. Tai, Y.H. Wang, T.Z. Liu, Y.M. Jen, and C.Y. Shiau Sorafenib induces preferential apoptotic killing of a drug- and radio-resistant Hep G2 cells through a mitochondria-dependent oxidative stress mechanism Cancer Biol Ther 8 2009 1904 1913
-
(2009)
Cancer Biol Ther
, vol.8
, pp. 1904-1913
-
-
Chiou, J.F.1
Tai, C.J.2
Wang, Y.H.3
Liu, T.Z.4
Jen, Y.M.5
Shiau, C.Y.6
-
40
-
-
20044382799
-
Phase i clinical and pharmacokinetic study of the Novel Raf kinase and vascular endothelial growth factor receptor inhibitor BAY 43-9006 in patients with advanced refractory solid tumors
-
D. Strumberg, H. Richly, and R.A. Hilger Phase I clinical and pharmacokinetic study of the Novel Raf kinase and vascular endothelial growth factor receptor inhibitor BAY 43-9006 in patients with advanced refractory solid tumors J Clin Oncol 23 2005 965 972
-
(2005)
J Clin Oncol
, vol.23
, pp. 965-972
-
-
Strumberg, D.1
Richly, H.2
Hilger, R.A.3
-
41
-
-
27444436166
-
Apoptosis induced by the kinase inhibitor BAY 43-9006 in human leukemia cells involves down-regulation of Mcl-1 through inhibition of translation
-
M. Rahmani, E.M. Davis, C. Bauer, P. Dent, and S. Grant Apoptosis induced by the kinase inhibitor BAY 43-9006 in human leukemia cells involves down-regulation of Mcl-1 through inhibition of translation J Biol Chem 280 2005 35217 35227
-
(2005)
J Biol Chem
, vol.280
, pp. 35217-35227
-
-
Rahmani, M.1
Davis, E.M.2
Bauer, C.3
Dent, P.4
Grant, S.5
-
42
-
-
79955809893
-
Sorafenib induces cell death in chronic lymphocytic leukemia by translational downregulation of Mcl-1
-
S. Huber, M. Oelsner, and T. Decker Sorafenib induces cell death in chronic lymphocytic leukemia by translational downregulation of Mcl-1 Leukemia 25 2011 838 847
-
(2011)
Leukemia
, vol.25
, pp. 838-847
-
-
Huber, S.1
Oelsner, M.2
Decker, T.3
-
43
-
-
77953679525
-
Tyrosine Kinase inhibitors Gefitinib, Lapatinib and Sorafenib induce rapid functional alterations in breast cancer cells
-
S. Carloni, F. Fabbri, and G. Brigliadori Tyrosine Kinase inhibitors Gefitinib, Lapatinib and Sorafenib induce rapid functional alterations in breast cancer cells Curr Cancer Drug Targets 10 2010 422 431
-
(2010)
Curr Cancer Drug Targets
, vol.10
, pp. 422-431
-
-
Carloni, S.1
Fabbri, F.2
Brigliadori, G.3
-
44
-
-
74549210540
-
Sorafenib blocks tumour growth, angiogenesis and metastatic potential in preclinical models of osteosarcoma through a mechanism potentially involving the inhibition of ERK1/2, MCL-1 and ezrin pathways
-
Y. Pignochino, G. Grignani, and G. Cavalloni Sorafenib blocks tumour growth, angiogenesis and metastatic potential in preclinical models of osteosarcoma through a mechanism potentially involving the inhibition of ERK1/2, MCL-1 and ezrin pathways Mol Cancer 8 2009 118
-
(2009)
Mol Cancer
, vol.8
, pp. 118
-
-
Pignochino, Y.1
Grignani, G.2
Cavalloni, G.3
-
45
-
-
51049101063
-
Down-regulation of myeloid cell leukemia-1 through inhibiting Erk/Pin 1 pathway by sorafenib facilitates chemosensitization in breast cancer
-
Q. Ding, L. Huo, and J.Y. Yang Down-regulation of myeloid cell leukemia-1 through inhibiting Erk/Pin 1 pathway by sorafenib facilitates chemosensitization in breast cancer Cancer Res 68 2008 6109 6117
-
(2008)
Cancer Res
, vol.68
, pp. 6109-6117
-
-
Ding, Q.1
Huo, L.2
Yang, J.Y.3
-
46
-
-
0034796595
-
Normalizing tumor vasculature with antiangiogenic therapy: A new paradigm for combination therapy
-
R.K. Jain Normalizing tumor vasculature with antiangiogenic therapy: a new paradigm for combination therapy Nat Med 7 2001 987 989
-
(2001)
Nat Med
, vol.7
, pp. 987-989
-
-
Jain, R.K.1
-
47
-
-
11844254414
-
Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
-
Rakesh.K. Jain Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy Science. 307 2005 58 62
-
(2005)
Science.
, vol.307
, pp. 58-62
-
-
Jain, Rakesh.K.1
|