Tyrosine kinase inhibitors gefitinib, lapatinib and sorafenib induce rapid functional alterations in breast cancer cells

Current Cancer Drug Targets

Volumn 10, Issue 4, 2010, Pages 422-431

  Carloni, S ^a   Fabbri, F ^a   Brigliadori, G ^a   Ulivi, P ^a   Silvestrini, R ^a   Amadori, D ^a   Zoli, W ^a  

^a DEPARTMENT OF MEDICAL ONCOLOGY   (Italy)

Author keywords

ABC transporters; Breast cancer; Calcium; In vitro study; Mitochondrial depolarization; Multidrug resistance; Tyrosine kinase inhibitor

Indexed keywords

CALCIUM; GEFITINIB; LAPATINIB; SORAFENIB; SULFORHODAMINE B;

APOPTOSIS; ARTICLE; BREAST CANCER; CALCIUM MOBILIZATION; CANCER CELL; CANCER CELL CULTURE; CANCER INHIBITION; CELL MEMBRANE DEPOLARIZATION; CYTOTOXICITY; DRUG EFFECT; ENDOPLASMIC RETICULUM; GENE EXPRESSION; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL MEMBRANE POTENTIAL; MULTIDRUG RESISTANCE; PROTEIN EXPRESSION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BASE SEQUENCE; BENZENESULFONATES; BREAST NEOPLASMS; CALCIUM; CELL DIVISION; CELL LINE, TUMOR; CYTOSOL; DNA PRIMERS; ENDOPLASMIC RETICULUM; FLOW CYTOMETRY; HUMANS; MEMBRANE POTENTIALS; PROTEIN KINASE INHIBITORS; PYRIDINES; QUINAZOLINES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 77953679525     PISSN: 15680096     EISSN: None     Source Type: Journal    
DOI: 10.2174/156800910791208580     Document Type: Article

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