-
1
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in caenorhabditis elegans
-
DOI 10.1038/35888
-
Fire, A, Xu, S, Montgomery, MK, Kostas, SA, Driver, SE and Mello, CC (1998). Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391: 806-811. (Pubitemid 28099681)
-
(1998)
Nature
, vol.391
, Issue.6669
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
2
-
-
0034737298
-
RNAi: Double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals
-
Zamore, PD, Tuschl, T, Sharp, PA and Bartel, DP (2000). RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell 101: 25-33.
-
(2000)
Cell
, vol.101
, pp. 25-33
-
-
Zamore, P.D.1
Tuschl, T.2
Sharp, P.A.3
Bartel, D.P.4
-
3
-
-
0034673638
-
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
-
DOI 10.1038/35005107
-
Hammond, SM, Bernstein, E, Beach, D and Hannon, GJ (2000). An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature 404: 293-296. (Pubitemid 30163547)
-
(2000)
Nature
, vol.404
, Issue.6775
, pp. 293-296
-
-
Hammond, S.M.1
Bernstein, E.2
Beach, D.3
Hannon, G.J.4
-
4
-
-
78751482329
-
How to slice: Snapshots of Argonaute in action
-
Parker, JS (2010). How to slice: snapshots of Argonaute in action. Silence 1: 3.
-
(2010)
Silence
, vol.1
, pp. 3
-
-
Parker, J.S.1
-
5
-
-
58749113430
-
A three-dimensional view of the molecular machinery of RNA interference
-
Jinek, M and Doudna, JA (2009). A three-dimensional view of the molecular machinery of RNA interference. Nature 457: 405-412.
-
(2009)
Nature
, vol.457
, pp. 405-412
-
-
Jinek, M.1
Doudna, J.A.2
-
6
-
-
2442679207
-
Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain
-
DOI 10.1038/nature02519
-
Ma, JB, Ye, K and Patel, DJ (2004). Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain. Nature 429: 318-322. (Pubitemid 38684819)
-
(2004)
Nature
, vol.429
, Issue.6989
, pp. 318-322
-
-
Ma, J.-B.1
Ye, K.2
Patel, D.J.3
-
7
-
-
3142613181
-
Single processing center models for human Dicer and bacterial RNase III
-
DOI 10.1016/j.cell.2004.06.017, PII S009286740400618X
-
Zhang, H, Kolb, FA, Jaskiewicz, L, Westhof, E and Filipowicz, W (2004). Single processing center models for human Dicer and bacterial RNase III. Cell 118: 57-68. (Pubitemid 38902814)
-
(2004)
Cell
, vol.118
, Issue.1
, pp. 57-68
-
-
Zhang, H.1
Kolb, F.A.2
Jaskiewicz, L.3
Westhof, E.4
Filipowicz, W.5
-
8
-
-
0036845374
-
Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP
-
DOI 10.1093/emboj/cdf582
-
Zhang, H, Kolb, FA, Brondani, V, Billy, E and Filipowicz, W (2002). Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP. EMBO J 21: 5875-5885. (Pubitemid 35315285)
-
(2002)
EMBO Journal
, vol.21
, Issue.21
, pp. 5875-5885
-
-
Zhang, H.1
Kolb, F.A.2
Brondani, V.3
Billy, E.4
Filipowicz, W.5
-
9
-
-
59049105558
-
Human Dicer binds short single-strand and double-strand RNA with high affinity and interacts with different regions of the nucleic acids
-
Lima, WF, Murray, H, Nichols, JG, Wu, H, Sun, H, Prakash, TP et al. (2009). Human Dicer binds short single-strand and double-strand RNA with high affinity and interacts with different regions of the nucleic acids. J Biol Chem 284: 2535-2548.
-
(2009)
J Biol Chem
, vol.284
, pp. 2535-2548
-
-
Lima, W.F.1
Murray, H.2
Nichols, J.G.3
Wu, H.4
Sun, H.5
Prakash, T.P.6
-
10
-
-
0035839109
-
Argonaute2, a link between genetic and biochemical analyses of RNAi
-
DOI 10.1126/science.1064023
-
Hammond, SM, Boettcher, S, Caudy, AA, Kobayashi, R and Hannon, GJ (2001). Argonaute2, a link between genetic and biochemical analyses of RNAi. Science 293: 1146-1150. (Pubitemid 32758097)
-
(2001)
Science
, vol.293
, Issue.5532
, pp. 1146-1150
-
-
Hammond, S.M.1
Boettcher, S.2
Caudy, A.A.3
Kobayashi, R.4
Hannon, G.J.5
-
11
-
-
0345490960
-
The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes
-
DOI 10.1038/nsb1016
-
Song, JJ, Liu, J, Tolia, NH, Schneiderman, J, Smith, SK, Martienssen, RA et al. (2003). The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes. Nat Struct Biol 10: 1026-1032. (Pubitemid 37500495)
-
(2003)
Nature Structural Biology
, vol.10
, Issue.12
, pp. 1026-1032
-
-
Song, J.-J.1
Liu, J.2
Tolia, N.H.3
Schneiderman, J.4
Smith, S.K.5
Martienssen, R.A.6
Hannon, G.J.7
Joshua-Tor, L.8
-
12
-
-
4444368187
-
Argonaute2 is the catalytic engine of mammalian RNAi
-
DOI 10.1126/science.1102513
-
Liu, J, Carmell, MA, Rivas, FV, Marsden, CG, Thomson, JM, Song, JJ et al. (2004). Argonaute2 is the catalytic engine of mammalian RNAi. Science 305: 1437-1441. (Pubitemid 39167657)
-
(2004)
Science
, vol.305
, Issue.5689
, pp. 1437-1441
-
-
Liu, J.1
Carmell, M.A.2
Rivas, F.V.3
Marsden, C.G.4
Thomson, J.M.5
Song, J.-J.6
Hammond, S.M.7
Joshua-Tor, L.8
Hannon, G.J.9
-
13
-
-
33746274670
-
Comprehensive thermodynamic analysis of 3' double-nucleotide overhangs neighboring Watson-Crick terminal base pairs
-
O'Toole, AS, Miller, S, Haines, N, Zink, MC and Serra, MJ (2006). Comprehensive thermodynamic analysis of 3' double-nucleotide overhangs neighboring Watson-Crick terminal base pairs. Nucleic Acids Res 34: 3338-3344.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 3338-3344
-
-
O'Toole, A.S.1
Miller, S.2
Haines, N.3
Zink, M.C.4
Serra, M.J.5
-
14
-
-
15444376018
-
Stability of 3′ double nucleotide overhangs that model the 3′ ends of siRNA
-
DOI 10.1261/rna.7254905
-
O'Toole, AS, Miller, S and Serra, MJ (2005). Stability of 3' double nucleotide overhangs that model the 3' ends of siRNA. RNA 11: 512-516. (Pubitemid 40397184)
-
(2005)
RNA
, vol.11
, Issue.4
, pp. 512-516
-
-
O'Toole, A.S.1
Miller, S.2
Serra, M.J.3
-
15
-
-
17844363243
-
The contributions of dsRNA structure to Dicer specificity and efficiency
-
DOI 10.1261/rna.7272305
-
Vermeulen, A, Behlen, L, Reynolds, A, Wolfson, A, Marshall, WS, Karpilow, J et al. (2005). The contributions of dsRNA structure to Dicer specificity and efficiency. RNA 11: 674-682. (Pubitemid 40594334)
-
(2005)
RNA
, vol.11
, Issue.5
, pp. 674-682
-
-
Vermeulen, A.1
Behlen, L.2
Reynolds, A.3
Wolfson, A.4
Marshall, W.S.5
Karpilow, J.6
Khvorova, A.7
-
16
-
-
13844280638
-
Synthetic shRNAs as potent RNAi triggers
-
DOI 10.1038/nbt1052
-
Siolas, D, Lerner, C, Burchard, J, Ge, W, Linsley, PS, Paddison, PJ et al. (2005). Synthetic shRNAs as potent RNAi triggers. Nat Biotechnol 23: 227-231. (Pubitemid 40255334)
-
(2005)
Nature Biotechnology
, vol.23
, Issue.2
, pp. 227-231
-
-
Siolas, D.1
Lerner, C.2
Burchard, J.3
Ge, W.4
Linsley, P.S.5
Paddison, P.J.6
Hannon, G.J.7
Cleary, M.A.8
-
17
-
-
13844281898
-
Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy
-
DOI 10.1038/nbt1051
-
Kim, DH, Behlke, MA, Rose, SD, Chang, MS, Choi, S and Rossi, JJ (2005). Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy. Nat Biotechnol 23: 222-226. (Pubitemid 40255333)
-
(2005)
Nature Biotechnology
, vol.23
, Issue.2
, pp. 222-226
-
-
Kim, D.-H.1
Behlke, M.A.2
Rose, S.D.3
Chang, M.-S.4
Choi, S.5
Rossi, J.J.6
-
18
-
-
1542336952
-
Rational siRNA design for RNA interference
-
DOI 10.1038/nbt936
-
Reynolds, A, Leake, D, Boese, Q, Scaringe, S, Marshall, WS and Khvorova, A (2004). Rational siRNA design for RNA interference. Nat Biotechnol 22: 326-330. (Pubitemid 38295766)
-
(2004)
Nature Biotechnology
, vol.22
, Issue.3
, pp. 326-330
-
-
Reynolds, A.1
Leake, D.2
Boese, Q.3
Scaringe, S.4
Marshall, W.S.5
Khvorova, A.6
-
19
-
-
77954073941
-
Continuous fluorescence-based method for assessing dicer cleavage efficiency reveals 3' overhang nucleotide preference
-
DiNitto, JP, Wang, L and Wu, JC (2010). Continuous fluorescence-based method for assessing dicer cleavage efficiency reveals 3' overhang nucleotide preference. BioTechniques 48: 303-311.
-
(2010)
BioTechniques
, vol.48
, pp. 303-311
-
-
Dinitto, J.P.1
Wang, L.2
Wu, J.C.3
-
20
-
-
0037089135
-
Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor
-
Holen, T, Amarzguioui, M, Wiiger, MT, Babaie, E and Prydz, H (2002). Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor. Nucleic Acids Res 30: 1757-1766. (Pubitemid 34679753)
-
(2002)
Nucleic Acids Research
, vol.30
, Issue.8
, pp. 1757-1766
-
-
Holen, T.1
Amarzguioui, M.2
Wiiger, M.T.3
Babaie, E.4
Prydz, H.5
-
21
-
-
66649131084
-
Structural and functional modules in RNA interference
-
Nowotny, M and Yang, W (2009). Structural and functional modules in RNA interference. Curr Opin Struct Biol 19: 286-293.
-
(2009)
Curr Opin Struct Biol
, vol.19
, pp. 286-293
-
-
Nowotny, M.1
Yang, W.2
-
22
-
-
22844448088
-
Functional polarity is introduced by Dicer processing of short substrate RNAs
-
DOI 10.1093/nar/gki732
-
Rose, SD, Kim, DH, Amarzguioui, M, Heidel, JD, Collingwood, MA, Davis, ME et al. (2005). Functional polarity is introduced by Dicer processing of short substrate RNAs. Nucleic Acids Res 33: 4140-4156. (Pubitemid 41487274)
-
(2005)
Nucleic Acids Research
, vol.33
, Issue.13
, pp. 4140-4156
-
-
Rose, S.D.1
Kim, D.-H.2
Amarzguioui, M.3
Heidel, J.D.4
Collingwood, M.A.5
Davis, M.E.6
Rossi, J.J.7
Behlke, M.A.8
-
23
-
-
84934436966
-
Principles of Dicer substrate (D-siRNA) design and function
-
Amarzguioui, M and Rossi, JJ (2008). Principles of Dicer substrate (D-siRNA) design and function. Methods Mol Biol 442: 3-10.
-
(2008)
Methods Mol Biol
, vol.442
, pp. 3-10
-
-
Amarzguioui, M.1
Rossi, J.J.2
-
24
-
-
33747748975
-
Rational design and in vitro and in vivo delivery of Dicer substrate siRNA
-
Amarzguioui, M, Lundberg, P, Cantin, E, Hagstrom, J, Behlke, MA and Rossi, JJ (2006). Rational design and in vitro and in vivo delivery of Dicer substrate siRNA. Nat Protoc 1: 508-517.
-
(2006)
Nat Protoc
, vol.1
, pp. 508-517
-
-
Amarzguioui, M.1
Lundberg, P.2
Cantin, E.3
Hagstrom, J.4
Behlke, M.A.5
Rossi, J.J.6
-
25
-
-
39349097864
-
Identification of host proteins required for HIV infection through a functional genomic screen
-
DOI 10.1126/science.1152725
-
Brass, AL, Dykxhoorn, DM, Benita, Y, Yan, N, Engelman, A, Xavier, RJ et al. (2008). Identification of host proteins required for HIV infection through a functional genomic screen. Science 319: 921-926. (Pubitemid 351263756)
-
(2008)
Science
, vol.319
, Issue.5865
, pp. 921-926
-
-
Brass, A.L.1
Dykxhoorn, D.M.2
Benita, Y.3
Yan, N.4
Engelman, A.5
Xavier, R.J.6
Lieberman, J.7
Elledge, S.J.8
-
26
-
-
71449095148
-
Distinct passenger strand and mRNA cleavage activities of human Argonaute proteins
-
Wang, B, Li, S, Qi, HH, Chowdhury, D, Shi, Y and Novina, CD (2009). Distinct passenger strand and mRNA cleavage activities of human Argonaute proteins. Nat Struct Mol Biol 16: 1259-1266.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 1259-1266
-
-
Wang, B.1
Li, S.2
Qi, H.H.3
Chowdhury, D.4
Shi, Y.5
Novina, C.D.6
-
27
-
-
70349961432
-
Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes
-
Wang, Y, Juranek, S, Li, H, Sheng, G, Wardle, GS, Tuschl, T et al. (2009). Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes. Nature 461: 754-761.
-
(2009)
Nature
, vol.461
, pp. 754-761
-
-
Wang, Y.1
Juranek, S.2
Li, H.3
Sheng, G.4
Wardle, G.S.5
Tuschl, T.6
-
28
-
-
36849013062
-
A stepwise model for double-stranded RNA processing by ribonuclease III
-
DOI 10.1111/j.1365-2958.2007.06032.x
-
Gan, J, Shaw, G, Tropea, JE, Waugh, DS, Court, DL and Ji, X (2008). A stepwise model for double-stranded RNA processing by ribonuclease III. Mol Microbiol 67: 143-154. (Pubitemid 350231141)
-
(2008)
Molecular Microbiology
, vol.67
, Issue.1
, pp. 143-154
-
-
Gan, J.1
Shaw, G.2
Tropea, J.E.3
Waugh, D.S.4
Court, D.L.5
Ji, X.6
-
29
-
-
2542461104
-
Nucleic acid 3′-end recognition by the Argonaute2 PAZ domain
-
DOI 10.1038/nsmb777
-
Lingel, A, Simon, B, Izaurralde, E and Sattler, M (2004). Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain. Nat Struct Mol Biol 11: 576-577. (Pubitemid 38691927)
-
(2004)
Nature Structural and Molecular Biology
, vol.11
, Issue.6
, pp. 576-577
-
-
Lingel, A.1
Simon, B.2
Izaurralde, E.3
Sattler, M.4
-
30
-
-
15844371219
-
Structural basis for 5′ -end-specific recognition of guide RNA by the A. fulgidus Piwi protein
-
DOI 10.1038/nature03514
-
Ma, JB, Yuan, YR, Meister, G, Pei, Y, Tuschl, T and Patel, DJ (2005). Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein. Nature 434: 666-670. (Pubitemid 40488561)
-
(2005)
Nature
, vol.434
, Issue.7033
, pp. 666-670
-
-
Ma, J.-B.1
Yuan, Y.-R.2
Meister, G.3
Pei, Y.4
Tuschl, T.5
Patel, D.J.6
-
31
-
-
15844402005
-
Structural insights into mRNA recognition from a PIWI domain-siRNA guide complex
-
DOI 10.1038/nature03462
-
Parker, JS, Roe, SM and Barford, D (2005). Structural insights into mRNA recognition from a PIWI domain-siRNA guide complex. Nature 434: 663-666. (Pubitemid 40488560)
-
(2005)
Nature
, vol.434
, Issue.7033
, pp. 663-666
-
-
Parker, J.S.1
Roe, S.M.2
Barford, D.3
-
32
-
-
33846781627
-
Contributions of 3′-overhang to the dissociation of small interfering RNAs from the PAZ domain: Molecular dynamics simulation study
-
DOI 10.1016/j.jmgm.2006.07.002, PII S1093326306001057
-
Lee, HS, Lee, SN, Joo, CH, Lee, H, Lee, HS, Yoon, SY et al. (2007). Contributions of 3'-overhang to the dissociation of small interfering RNAs from the PAZ domain: molecular dynamics simulation study. J Mol Graph Model 25: 784-793. (Pubitemid 46216113)
-
(2007)
Journal of Molecular Graphics and Modelling
, vol.25
, Issue.6
, pp. 784-793
-
-
Lee, H.S.1
Lee, S.N.2
Joo, C.H.3
Lee, H.4
Lee, H.S.5
Yoon, S.Y.6
Kim, Y.K.7
Choe, H.8
-
33
-
-
70349866687
-
ShortRead: A bioconductor package for input, quality assessment and exploration of highthroughput sequence data
-
Morgan, M, Anders, S, Lawrence, M, Aboyoun, P, Pagès, H and Gentleman, R (2009). ShortRead: a bioconductor package for input, quality assessment and exploration of highthroughput sequence data. Bioinformatics 25: 2607-2608.
-
(2009)
Bioinformatics
, vol.25
, pp. 2607-2608
-
-
Morgan, M.1
Anders, S.2
Lawrence, M.3
Aboyoun, P.4
Pagès, H.5
Gentleman, R.6
-
34
-
-
36448991500
-
Clustal W and Clustal X version 2.0
-
DOI 10.1093/bioinformatics/btm404
-
Larkin, MA, Blackshields, G, Brown, NP, Chenna, R, McGettigan, PA, McWilliam, H et al. (2007). Clustal W and Clustal X version 2.0. Bioinformatics 23: 2947-2948. (Pubitemid 350162903)
-
(2007)
Bioinformatics
, vol.23
, Issue.21
, pp. 2947-2948
-
-
Larkin, M.A.1
Blackshields, G.2
Brown, N.P.3
Chenna, R.4
Mcgettigan, P.A.5
McWilliam, H.6
Valentin, F.7
Wallace, I.M.8
Wilm, A.9
Lopez, R.10
Thompson, J.D.11
Gibson, T.J.12
Higgins, D.G.13
-
35
-
-
65449188232
-
Jalview Version 2 - A multiple sequence alignment editor and analysis workbench
-
Waterhouse, AM, Procter, JB, Martin, DM, Clamp, M and Barton, GJ (2009). Jalview Version 2-a multiple sequence alignment editor and analysis workbench. Bioinformatics 25: 1189-1191.
-
(2009)
Bioinformatics
, vol.25
, pp. 1189-1191
-
-
Waterhouse, A.M.1
Procter, J.B.2
Martin, D.M.3
Clamp, M.4
Barton, G.J.5
|