메뉴 건너뛰기




Volumn 442, Issue , 2008, Pages 3-10

Principles of dicer substrate (D-siRNA) design and function

Author keywords

Dicer; RNAi; ShRNA; SiRNA

Indexed keywords


EID: 84934436966     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-59745-191-8_1     Document Type: Article
Times cited : (46)

References (27)
  • 1
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire, A., Xu, S., Montgomery, M. K., Kostas, S. A., Driver, S. E., and Mello, C. C. (1998). Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391, 806-811.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 2
    • 4644350944 scopus 로고    scopus 로고
    • Unlocking the potential of the human genome with RNA interference
    • Hannon, G. J., and Rossi, J. J. (2004). Unlocking the potential of the human genome with RNA interference. Nature 431, 371-378.
    • (2004) Nature , vol.431 , pp. 371-378
    • Hannon, G.J.1    Rossi, J.J.2
  • 3
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir, S. M., Harborth, J., Lendeckel, W., Yalcin, A., Weber, K., and Tuschl, T. (2001). Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411, 494-498.
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 4
    • 0037685280 scopus 로고    scopus 로고
    • Expression profiling reveals off-target gene regulation by RNAi
    • Jackson, A. L., Bartz, S. R., Schelter, J., et al. (2003). Expression profiling reveals off-target gene regulation by RNAi. Nat. Biotechnol. 21, 635-637.
    • (2003) Nat. Biotechnol , vol.21 , pp. 635-637
    • Jackson, A.L.1    Bartz, S.R.2    Schelter, J.3
  • 6
    • 13844280638 scopus 로고    scopus 로고
    • Synthetic shRNAs as potent RNAi triggers
    • Siolas, D., Lerner, C., Burchard, J., et al. (2005). Synthetic shRNAs as potent RNAi triggers. Nat. Biotechnol. 23, 227-231.
    • (2005) Nat. Biotechnol , vol.23 , pp. 227-231
    • Siolas, D.1    Lerner, C.2    Burchard, J.3
  • 7
    • 1842766252 scopus 로고    scopus 로고
    • A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila
    • Pham, J. W., Pellino, J. L., Lee, Y. S., Carthew, R. W., and Sontheimer, E. J. (2004). A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila. Cell 117, 83-94.
    • (2004) Cell , vol.117 , pp. 83-94
    • Pham, J.W.1    Pellino, J.L.2    Lee, Y.S.3    Carthew, R.W.4    Sontheimer, E.J.5
  • 8
    • 27744537851 scopus 로고    scopus 로고
    • Gregory, R. 1., Chendrimada, T. P., Cooch, N., and Shiekhattar, R. (2005). Human RISC couples microRNA biogenesis and posttranscriptional gene silencing. Cell 123, 631-640.
    • Gregory, R. 1., Chendrimada, T. P., Cooch, N., and Shiekhattar, R. (2005). Human RISC couples microRNA biogenesis and posttranscriptional gene silencing. Cell 123, 631-640.
  • 9
    • 29144431656 scopus 로고    scopus 로고
    • A human, ATP-independent, RISC assembly machine fueled by pre-miRNA
    • Maniataki, E., and Mourelatos, Z. (2005). A human, ATP-independent, RISC assembly machine fueled by pre-miRNA. Genes Dev. 19, 2979-2990.
    • (2005) Genes Dev , vol.19 , pp. 2979-2990
    • Maniataki, E.1    Mourelatos, Z.2
  • 10
    • 4744357297 scopus 로고    scopus 로고
    • Structural features of microRNA (miRNA) precursors and their relevance to miRNA biogenesis and small interfering RNA/short hairpin RNA design
    • Krol, J., Sobczak, K., Wilczynska, U., et al. (2004). Structural features of microRNA (miRNA) precursors and their relevance to miRNA biogenesis and small interfering RNA/short hairpin RNA design. J. Biol. Chem. 279, 42230-42239.
    • (2004) J. Biol. Chem , vol.279 , pp. 42230-42239
    • Krol, J.1    Sobczak, K.2    Wilczynska, U.3
  • 11
    • 22844448088 scopus 로고    scopus 로고
    • Functional polarity is introduced by Dicer processing of short substrate RNAs
    • Rose, S. D., Kim, D. H., Amarzguioui, M., et al. (2005). Functional polarity is introduced by Dicer processing of short substrate RNAs. Nucleic Acids Res. 33, 4140-4156.
    • (2005) Nucleic Acids Res , vol.33 , pp. 4140-4156
    • Rose, S.D.1    Kim, D.H.2    Amarzguioui, M.3
  • 12
    • 0035863097 scopus 로고    scopus 로고
    • RNA interference is mediated by 21- and 22-nucleotide RNAs
    • Elbashir, S. M., Lendeckel, W., and Tuschl, T. (2001). RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev. 15, 188-200.
    • (2001) Genes Dev , vol.15 , pp. 188-200
    • Elbashir, S.M.1    Lendeckel, W.2    Tuschl, T.3
  • 13
    • 26444437334 scopus 로고    scopus 로고
    • siRNA target site secondary structure predictions using local stable substructures
    • Heale, B. S., Soifer, H. S., Bowers, C., and Rossi, J. J. (2005). siRNA target site secondary structure predictions using local stable substructures. Nucleic Acids Res. 33, e30.
    • (2005) Nucleic Acids Res , vol.33
    • Heale, B.S.1    Soifer, H.S.2    Bowers, C.3    Rossi, J.J.4
  • 14
    • 0037440005 scopus 로고    scopus 로고
    • Tolerance for mutations and chemical modifications in a siRNA
    • Amarzguioui, M., Holen, T., Babaie, E., and Prydz, H. (2003). Tolerance for mutations and chemical modifications in a siRNA. Nucleic Acids Res. 31, 589-595.
    • (2003) Nucleic Acids Res , vol.31 , pp. 589-595
    • Amarzguioui, M.1    Holen, T.2    Babaie, E.3    Prydz, H.4
  • 15
    • 15044358407 scopus 로고    scopus 로고
    • A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites
    • Du, Q., Thonberg, H., Wang, J., Wahlestedt, C., and Liang, Z. (2005). A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites. Nucleic Acids Res. 33, 1671-1677.
    • (2005) Nucleic Acids Res , vol.33 , pp. 1671-1677
    • Du, Q.1    Thonberg, H.2    Wang, J.3    Wahlestedt, C.4    Liang, Z.5
  • 16
    • 0035803583 scopus 로고    scopus 로고
    • Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysáte
    • Elbashir, S. M., Martinez, J., Patkaniowska, A., Lendeckel, W., and Tuschl, T. (2001). Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysáte. EMBO J. 20, 6877-6888.
    • (2001) EMBO J , vol.20 , pp. 6877-6888
    • Elbashir, S.M.1    Martinez, J.2    Patkaniowska, A.3    Lendeckel, W.4    Tuschl, T.5
  • 17
    • 0037089135 scopus 로고    scopus 로고
    • Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor
    • Holen, T., Amarzguioui, M., Wiiger, M. T., Babaie, E., and Prydz, H. (2002). Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor. Nucleic Acids Res. 30, 1757-1766.
    • (2002) Nucleic Acids Res , vol.30 , pp. 1757-1766
    • Holen, T.1    Amarzguioui, M.2    Wiiger, M.T.3    Babaie, E.4    Prydz, H.5
  • 18
    • 1342306385 scopus 로고    scopus 로고
    • Targeting Alzheimer's disease genes with RNA interference: An efficient strategy for silencing mutant alleles
    • Miller, V. M., Gouvion, C. M., Davidson, B. L., and Paulson, H. L. (2004). Targeting Alzheimer's disease genes with RNA interference: An efficient strategy for silencing mutant alleles. Nucleic Acids Res. 32, 661-668.
    • (2004) Nucleic Acids Res , vol.32 , pp. 661-668
    • Miller, V.M.1    Gouvion, C.M.2    Davidson, B.L.3    Paulson, H.L.4
  • 19
    • 33646188259 scopus 로고    scopus 로고
    • 3' UTR seed matches, but not overall identity, are associated with RNAi off-targets
    • Birmingham, A., Anderson, E. M., Reynolds, A., et al. (2006). 3' UTR seed matches, but not overall identity, are associated with RNAi off-targets. Nat. Meth. 3, 199-204.
    • (2006) Nat. Meth , vol.3 , pp. 199-204
    • Birmingham, A.1    Anderson, E.M.2    Reynolds, A.3
  • 20
    • 20144389695 scopus 로고    scopus 로고
    • Sequence-specific potent induction of IFN-a by short interfering RNA in plasmacytoid dendritic cells through TLR7
    • Hornung, V., Guenthner-Biller, M., Bourquin, C., et al. (2005). Sequence-specific potent induction of IFN-a by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat. Med. 11, 263-270.
    • (2005) Nat. Med , vol.11 , pp. 263-270
    • Hornung, V.1    Guenthner-Biller, M.2    Bourquin, C.3
  • 21
    • 22344454846 scopus 로고    scopus 로고
    • Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA
    • Judge, A. D., Sood, V., Shaw, J. R., Fang, D., McClintock, K., and MacLachlan, I. (2005). Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat. Biotechnol. 23, 457-562.
    • (2005) Nat. Biotechnol , vol.23 , pp. 457-562
    • Judge, A.D.1    Sood, V.2    Shaw, J.R.3    Fang, D.4    McClintock, K.5    MacLachlan, I.6
  • 22
    • 2442705429 scopus 로고    scopus 로고
    • Small interfering RNAsmediate sequence-independent gene suppression and induce immune activation by signaling through Toll-like receptor 3
    • Kariko, K., Bhuyan, P., Capodici, J., and Weissman, D. (2004). Small interfering RNAsmediate sequence-independent gene suppression and induce immune activation by signaling through Toll-like receptor 3. J. Immunol. 172, 6545-6549.
    • (2004) J. Immunol , vol.172 , pp. 6545-6549
    • Kariko, K.1    Bhuyan, P.2    Capodici, J.3    Weissman, D.4
  • 23
    • 16244377102 scopus 로고    scopus 로고
    • Sensing the danger in RNA
    • Robbins, M. A., and Rossi, J. J. (2005). Sensing the danger in RNA. Nat. Med. 11, 250-251.
    • (2005) Nat. Med , vol.11 , pp. 250-251
    • Robbins, M.A.1    Rossi, J.J.2
  • 24
    • 18044365415 scopus 로고    scopus 로고
    • Induction of inflammatory cytokines and interferon responses by double- stranded and single-stranded siRNAs is sequence-dependent and requires endosomal localization
    • Sioud, M. (2005). Induction of inflammatory cytokines and interferon responses by double- stranded and single-stranded siRNAs is sequence-dependent and requires endosomal localization. J. Mol. Biol. 348, 1079-1090.
    • (2005) J. Mol. Biol , vol.348 , pp. 1079-1090
    • Sioud, M.1
  • 25
    • 33646561864 scopus 로고    scopus 로고
    • A structural basis for discriminating between self and nonself double-stranded RNAs in mammalian cells
    • Marques, J. T., Devosse, T., Wang, D., et al. (2006). A structural basis for discriminating between self and nonself double-stranded RNAs in mammalian cells. Nat. Biotechnol. 24, 559-565.
    • (2006) Nat. Biotechnol , vol.24 , pp. 559-565
    • Marques, J.T.1    Devosse, T.2    Wang, D.3
  • 26
    • 2442610892 scopus 로고    scopus 로고
    • Improved siRNA-mediated silencing in refractory adherent cell lines by detachment and transfection in suspension
    • Amarzguioui, M. (2004). Improved siRNA-mediated silencing in refractory adherent cell lines by detachment and transfection in suspension. Biotechniques 36, 766-768, 770.
    • (2004) Biotechniques , vol.36 , Issue.766-768 , pp. 770
    • Amarzguioui, M.1
  • 27
    • 33748078159 scopus 로고    scopus 로고
    • Partnering aptamer and RNAi technologies
    • Rossi, J. J. (2006). Partnering aptamer and RNAi technologies. MoI. Ther. 14, 461-462.
    • (2006) MoI. Ther , vol.14 , pp. 461-462
    • Rossi, J.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.