Combined effects of agitation, macromolecular crowding, and interfaces on amyloidogenesis

Journal of Biological Chemistry

Volumn 287, Issue 45, 2012, Pages 38006-38019

  Lee, Chiu Fan ^b   Bird, Sarah ^c   Shaw, Michael ^a   Jean, Létitia ^a   Vaux, David J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b MAX PLANCK INSTITUT FÜR PHYSIK KOMPLEXER SYSTEME   (Germany)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOIDOGENESIS; COMBINED EFFECT; EXCLUDED VOLUME EFFECTS; HYDROPHOBIC-HYDROPHILIC; MACROMOLECULAR CROWDING; SPATIAL HETEROGENEITY;

HYDROPHILICITY; HYDROPHOBICITY;

MACROMOLECULES;

AMYLOID BETA PROTEIN; DEXTRAN; FICOLL; POLYMER; SURFACTANT;

ALZHEIMER DISEASE; AMYLOIDOGENESIS; ARTICLE; DISEASE PREDISPOSITION; HYDROPHILICITY; HYDROPHOBICITY; MACROMOLECULE; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN METABOLISM; PROTEIN POLYMORPHISM; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; VISCOSITY;

ALZHEIMER DISEASE; AMYLOID; AMYLOID BETA-PEPTIDES; DEXTRANS; DIABETES MELLITUS, TYPE 2; FICOLL; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MACROMOLECULAR SUBSTANCES; MICROSCOPY, ELECTRON; SOLUTIONS; VIBRATION; VISCOSITY;

EID: 84868325436     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.400580     Document Type: Article

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