Ultrasensitive human prion detection in cerebrospinal fluid by real-time quaking-induced conversion

Nature Medicine

Volumn 17, Issue 2, 2011, Pages 175-178

  Atarashi, Ryuichiro ^a   Satoh, Katsuya ^a   Sano, Kazunori ^a   Fuse, Takayuki ^a   Yamaguchi, Naohiro ^a   Ishibashi, Daisuke ^a   Matsubara, Takehiro ^a   Nakagaki, Takehiro ^a   Yamanaka, Hitoki ^a   Shirabe, Susumu ^b   Yamada, Masahito ^c   Mizusawa, Hidehiro ^d   Kitamoto, Tetsuyuki ^e   Klug, Genevieve ^f   McGlade, Amelia ^f   Collins, Steven J ^f   Nishida, Noriyuki ^a  

^a NAGASAKI UNIVERSITY   (Japan)

^b NAGASAKI UNIVERSITY HOSPITAL   (Japan)

^c KANAZAWA UNIVERSITY   (Japan)

^d TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^e TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^f UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

PRION PROTEIN;

ADULT; AGED; ARTICLE; CEREBROSPINAL FLUID; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CREUTZFELDT JAKOB DISEASE; FEMALE; HUMAN; MALE; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY;

BIOLOGICAL MARKERS; BRAIN; CREUTZFELDT-JAKOB SYNDROME; FLUORESCENT DYES; HUMANS; MOTION; PRIONS; PRPSC PROTEINS; SENSITIVITY AND SPECIFICITY; THIAZOLES;

EID: 79751535822     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.2294     Document Type: Article

References (18)

1. Prusiner, S.B. Proc. Natl. Acad. Sci. USA 95, 13363-13383 (1998).
2. Aguzzi, A. & Calella, A.M. Physiol. Rev. 89, 1105-1152 (2009).
3. Lasmezas, C.I. et al. Science 275, 402-405 (1997).
4. Gambetti, P. et al. Ann. Neurol. 63, 697-708 (2008).
5. Saborio, G.P., Permanne, B. & Soto, C. Nature 411, 810-813 (2001).
6. Castilla, J. et al. Methods Enzymol. 412, 3-21 (2006).
7. Atarashi, R. et al. Nat. Methods 4, 645-650 (2007).
8. Colby, D.W. et al. Proc. Natl. Acad. Sci. USA 104, 20914-20919 (2007).
9. Atarashi, R. et al. Nat. Methods 5, 211-212 (2008).
10. Orru, C.D. et al. Protein Eng. Des. Sel. 22, 515-521 (2009).
11. Kocisko, D.A. et al. Nature 370, 471-474 (1994).
12. Toth, S.I., Smith, L.A. & Ahmed, S.A. J. Pharm. Sci. 98, 3302-3311 (2009).
13. Collins, S.R., Douglass, A., Vale, R.D. & Weissman, J.S. PLoS Biol. 2, e321 (2004).
14. Lansbury, P.T. Jr. & Caughey, B. Chem. Biol. 2, 1-5 (1995).
15. Hsich, G., Kenney, K., Gibbs, C.J., Lee, K.H. & Harrington, M.G. N. Engl. J. Med. 335, 924-930 (1996).
16. Zerr, I. et al. Ann. Neurol. 43, 32-40 (1998).
17. Parchi, P. et al. Ann. Neurol. 46, 224-233 (1999).
18. Satoh, K. et al. Lab. Invest. 90, 1637-1644 (2010).