Critical role of interfaces and agitation on the nucleation of Aβ amyloid fibrils at low concentrations of Aβ monomers

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1804, Issue 4, 2010, Pages 986-995

  Morinaga, Akiyoshi ^a,b   Hasegawa, Kazuhiro ^a   Nomura, Ryo ^a   Ookoshi, Tadakazu ^a   Ozawa, Daisaku ^a   Goto, Yuji ^c   Yamada, Masahito ^b   Naiki, Hironobu ^a  

^a Faculty of Medical Sciences   (Japan)

^b KANAZAWA UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCE   (Japan)

^c OSAKA UNIVERSITY   (Japan)

Author keywords

Air water interface; Amyloid peptide; Amyloid fibril; Amyloidosis; Nucleation

Indexed keywords

ABETA AMYLOID FIBRIL; AMYLOID; MONOMER; POLYPROPYLENE; THIOFLAVINE; UNCLASSIFIED DRUG;

ARTICLE; FLUORESCENCE MICROSCOPY; FLUORESCENCE SPECTROSCOPY; KINETICS; POLYMERIZATION; PRIORITY JOURNAL;

AIR; ALZHEIMER DISEASE; AMYLOID; AMYLOID BETA-PROTEIN; BRAIN CHEMISTRY; FLUORESCENT DYES; HUMANS; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSCOPY, FLUORESCENCE; NEURODEGENERATIVE DISEASES; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; SOLUTIONS; SPECTROMETRY, FLUORESCENCE; THIAZOLES; WATER;

EID: 76849106756     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2010.01.012     Document Type: Article

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