-
1
-
-
0034958947
-
Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care
-
Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med. 2001;29(7):1303-10.
-
(2001)
Crit Care Med
, vol.29
, Issue.7
, pp. 1303-1310
-
-
Angus, D.C.1
Linde-Zwirble, W.T.2
Lidicker, J.3
Clermont, G.4
Carcillo, J.5
Pinsky, M.R.6
-
2
-
-
0037451929
-
The epidemiology of sepsis in the United States from 1979 through 2000
-
Martin GS, Mannino DM, Eaton S, Moss M. The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med. 2003;348(16):1546-54.
-
(2003)
N Engl J Med
, vol.348
, Issue.16
, pp. 1546-1554
-
-
Martin, G.S.1
Mannino, D.M.2
Eaton, S.3
Moss, M.4
-
3
-
-
31344461826
-
Sepsis in European intensive care units: Results of the SOAP study
-
Vincent JL, Sakr Y, Sprung CL, Ranieri VM, Reinhart K, Gerlach H, Moreno R, Carlet J, Le Gall JR, Payen D. Sepsis in European intensive care units: results of the SOAP study. Crit Care Med. 2006;34(2):344-53.
-
(2006)
Crit Care Med
, vol.34
, Issue.2
, pp. 344-353
-
-
Vincent, J.L.1
Sakr, Y.2
Sprung, C.L.3
Ranieri, V.M.4
Reinhart, K.5
Gerlach, H.6
Moreno, R.7
Carlet, J.8
Le Gall, J.R.9
Payen, D.10
-
4
-
-
70350642050
-
Deaths: Final data for 2006
-
Heron M, Hoyert DL, Murphy SL, Xu J, Kochanek KD, Tejada-Vera B. Deaths: final data for 2006. Natl Vital Stat Rep. 2009;57(14):1-134.
-
(2009)
Natl Vital Stat Rep
, vol.57
, Issue.14
, pp. 1-134
-
-
Heron, M.1
Hoyert, D.L.2
Murphy, S.L.3
Xu, J.4
Kochanek, K.D.5
Tejada-Vera, B.6
-
5
-
-
0035929575
-
Deaths: Final data for 1999
-
Hoyert DL, Arias E, Smith BL, Murphy SL, Kochanek KD. Deaths: final data for 1999. Natl Vital Stat Rep. 2001;49(8):1-113.
-
(2001)
Natl Vital Stat Rep
, vol.49
, Issue.8
, pp. 1-113
-
-
Hoyert, D.L.1
Arias, E.2
Smith, B.L.3
Murphy, S.L.4
Kochanek, K.D.5
-
6
-
-
0042832200
-
Long-term mortality and medical care charges in patients with severe sepsis
-
Weycker D, Akhras KS, Edelsberg J, Angus DC, Oster G. Long-term mortality and medical care charges in patients with severe sepsis. Crit Care Med. 2003;31(9):2316-23.
-
(2003)
Crit Care Med
, vol.31
, Issue.9
, pp. 2316-2323
-
-
Weycker, D.1
Akhras, K.S.2
Edelsberg, J.3
Angus, D.C.4
Oster, G.5
-
7
-
-
0033590515
-
Treating patients with severe sepsis
-
Wheeler AP, Bernard GR. Treating patients with severe sepsis. N Engl J Med. 1999;340(3):207-14.
-
(1999)
N Engl J Med
, vol.340
, Issue.3
, pp. 207-214
-
-
Wheeler, A.P.1
Bernard, G.R.2
-
8
-
-
0034924156
-
Epidemiology of sepsis: An update
-
Angus DC, Wax RS. Epidemiology of sepsis: an update. Crit Care Med. 2001;29(7 suppl):S109-16.
-
(2001)
Crit Care Med
, vol.29
, Issue.7 SUPPL.
-
-
Angus, D.C.1
Wax, R.S.2
-
9
-
-
0030854780
-
Epidemiology of sepsis syndrome in 8 academic medical centers
-
Sands KE, Bates DW, Lanken PN, Graman PS, Hibberd PL, Kahn KL, Parsonnet J, Panzer R, Orav EJ, Snydman DR, Black E, Schwartz JS, Moore R, Johnson BL Jr, Platt BL. Epidemiology of sepsis syndrome in 8 academic medical centers. JAMA. 1997;278(3):234-40.
-
(1997)
JAMA
, vol.278
, Issue.3
, pp. 234-240
-
-
Sands, K.E.1
Bates, D.W.2
Lanken, P.N.3
Graman, P.S.4
Hibberd, P.L.5
Kahn, K.L.6
Parsonnet, J.7
Panzer, R.8
Orav, E.J.9
Snydman, D.R.10
Black, E.11
Schwartz, J.S.12
Moore, R.13
Johnson Jr., B.L.14
Platt, B.L.15
-
10
-
-
0025303027
-
Septic shock in humans. Advances in the understanding of pathogenesis, cardiovascular dysfunction, and therapy
-
Parrillo JE, Parker MM, Natanson C, Suffredini AF, Danner RL, Cunnion RE, Ognibene FP. Septic shock in humans. Advances in the understanding of pathogenesis, cardiovascular dysfunction, and therapy. Ann Intern Med. 1990;113(3):227-42.
-
(1990)
Ann Intern Med
, vol.113
, Issue.3
, pp. 227-242
-
-
Parrillo, J.E.1
Parker, M.M.2
Natanson, C.3
Suffredini, A.F.4
Danner, R.L.5
Cunnion, R.E.6
Ognibene, F.P.7
-
11
-
-
0033710233
-
Long-term health-related quality of life in survivors of sepsis. Short Form 36: A valid and reliable measure of health-related quality of life
-
Heyland DK, Hopman W, Coo H, Tranmer J, McColl MA. Long-term health-related quality of life in survivors of sepsis. Short Form 36: a valid and reliable measure of health-related quality of life. Crit Care Med. 2000;28(11):3599-605.
-
(2000)
Crit Care Med
, vol.28
, Issue.11
, pp. 3599-3605
-
-
Heyland, D.K.1
Hopman, W.2
Coo, H.3
Tranmer, J.4
McColl, M.A.5
-
12
-
-
0029115513
-
Long-term survival and function after suspected gram-negative sepsis
-
Perl TM, Dvorak L, Hwang T, Wenzel RP. Long-term survival and function after suspected gram-negative sepsis. JAMA. 1995;274(4):338-45.
-
(1995)
JAMA
, vol.274
, Issue.4
, pp. 338-345
-
-
Perl, T.M.1
Dvorak, L.2
Hwang, T.3
Wenzel, R.P.4
-
13
-
-
0025710312
-
Increase in National Hospital Discharge Survey rates for septicemia-United States, 1979-1987
-
19
-
Increase in National Hospital Discharge Survey rates for septicemia-United States, 1979-1987. MMWR Morb Mortal Wkly Rep. 1990;19;39(2):31-4.
-
(1990)
MMWR Morb Mortal Wkly Rep
, vol.39
, Issue.2
, pp. 31-34
-
-
-
14
-
-
0037588986
-
The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome
-
Aird WC. The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome. Blood. 2003;101(10):3765-77.
-
(2003)
Blood
, vol.101
, Issue.10
, pp. 3765-3777
-
-
Aird, W.C.1
-
15
-
-
77956258291
-
The endothelium: Physiological functions and role in microcirculatory failure during severe sepsis
-
Ait-Oufella H, Maury E, Lehoux S, Guidet B, Offenstadt G. The endothelium: physiological functions and role in microcirculatory failure during severe sepsis. Intensive Care Med. 2010;36(8):1286-98.
-
(2010)
Intensive Care Med
, vol.36
, Issue.8
, pp. 1286-1298
-
-
Ait-Oufella, H.1
Maury, E.2
Lehoux, S.3
Guidet, B.4
Offenstadt, G.5
-
16
-
-
34447623219
-
Bench-to-bedside review: Potential strategies to protect or reverse mitochondrial dysfunction in sepsis-induced organ failure
-
Protti A, Singer M. Bench-to-bedside review: potential strategies to protect or reverse mitochondrial dysfunction in sepsis-induced organ failure. Crit Care. 2006;10(5):228-34.
-
(2006)
Crit Care
, vol.10
, Issue.5
, pp. 228-234
-
-
Protti, A.1
Singer, M.2
-
17
-
-
68049089963
-
Microcirculation and mitochondria in sepsis: Getting out of breath
-
Balestra GM, Legrand M, Ince C. Microcirculation and mitochondria in sepsis: getting out of breath. Curr.Opin Anaesthesiol. 2009;22(2):184-90.
-
(2009)
Curr.Opin Anaesthesiol
, vol.22
, Issue.2
, pp. 184-190
-
-
Balestra, G.M.1
Legrand, M.2
Ince, C.3
-
19
-
-
74949117097
-
Inflammation and coagulation
-
Levi M, van der Poll T. Inflammation and coagulation. Crit Care Med. 2010;38(2 suppl):S26-S34.
-
(2010)
Crit Care Med
, vol.38
, Issue.2 SUPPL.
-
-
Levi, M.1
van der Poll, T.2
-
20
-
-
33751552449
-
Historical perspective of the word sepsis
-
Geroulanos S, Douka ET. Historical perspective of the word sepsis. Intensive Care Med. 2006;32(12):2077.
-
(2077)
Intensive Care Med
, vol.32
, Issue.12
, pp. 2006
-
-
Geroulanos, S.1
Douka, E.T.2
-
21
-
-
1842738565
-
Evolution of virulence
-
Ewald PW. Evolution of virulence. Infect.Dis.Clin.North Am. 2004;18(1):1-15.
-
(2004)
Infect.Dis.Clin.North Am
, vol.18
, Issue.1
, pp. 1-15
-
-
Ewald, P.W.1
-
22
-
-
53549101646
-
Clinical sepsis and septic shock-definition, diagnosis and management principles
-
Vincent JL. Clinical sepsis and septic shock-definition, diagnosis and management principles. Langenbecks Arch.Surg. 2008;393(6):817-24.
-
(2008)
Langenbecks Arch.Surg
, vol.393
, Issue.6
, pp. 817-824
-
-
Vincent, J.L.1
-
23
-
-
0000372097
-
Wesen und Behandlung der Sepsis
-
Schottmueller H(1914)
-
Schottmueller H(1914). Wesen und Behandlung der Sepsis. Inn Med 2009;31:257-80.
-
(2009)
Inn Med
, vol.31
, pp. 257-280
-
-
-
24
-
-
0026874127
-
American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis
-
American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med. 1992;20(6):864-74.
-
(1992)
Crit Care Med
, vol.20
, Issue.6
, pp. 864-874
-
-
-
25
-
-
0037389094
-
2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference
-
Levy MM, Fink MP, Marshall JC, Abraham E, Angus D, Cook D, Cohen J, Opal SM, Vincent JL, Ramsay G. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med. 2003;31(4):1250-6.
-
(2003)
Crit Care Med
, vol.31
, Issue.4
, pp. 1250-1256
-
-
Levy, M.M.1
Fink, M.P.2
Marshall, J.C.3
Abraham, E.4
Angus, D.5
Cook, D.6
Cohen, J.7
Opal, S.M.8
Vincent, J.L.9
Ramsay, G.10
-
26
-
-
0026710191
-
Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine
-
Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, Schein RM, Sibbald WJ. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest. 1992;101(6):1644-55.
-
(1992)
Chest
, vol.101
, Issue.6
, pp. 1644-1655
-
-
Bone, R.C.1
Balk, R.A.2
Cerra, F.B.3
Dellinger, R.P.4
Fein, A.M.5
Knaus, W.A.6
Schein, R.M.7
Sibbald, W.J.8
-
27
-
-
54149112976
-
Biomarkers: Diagnosis and risk assessment in sepsis
-
Ventetuolo CE, Levy MM. Biomarkers: diagnosis and risk assessment in sepsis. Clin.Chest Med. 2008;29(4):591-603+vii.
-
(2008)
Clin.Chest Med
, vol.29
, Issue.4
-
-
Ventetuolo, C.E.1
Levy, M.M.2
-
28
-
-
77951056974
-
Approaching clinical reality: Markers for monitoring systemic inflammation and sepsis
-
Claus RA, Otto GP, Deigner HP, Bauer M. Approaching clinical reality: markers for monitoring systemic inflammation and sepsis. Curr Mol Med. 2010;10(2):227-35.
-
(2010)
Curr Mol Med
, vol.10
, Issue.2
, pp. 227-235
-
-
Claus, R.A.1
Otto, G.P.2
Deigner, H.P.3
Bauer, M.4
-
29
-
-
84861199459
-
Sepsis: Something old, something new, and a systems view
-
Namas R, Zamora R, Namas R, An G, Doyle J, Dick TE, Jacono FJ, Androulakis IP, Chang S, Billiar TR, Kellum JA, Angus DC, Vodovotz Y. Sepsis: Something old, something new, and a systems view. J Crit Care 2012;Jun:27(3):314.e1-11.
-
(2012)
J Crit Car
, vol.27
, Issue.3
-
-
Namas, R.1
Zamora, R.2
Namas, R.3
An, G.4
Doyle, J.5
Dick, T.E.6
Jacono, F.J.7
Androulakis, I.P.8
Chang, S.9
Billiar, T.R.10
Kellum, J.A.11
Angus, D.C.12
Vodovotz, Y.13
-
30
-
-
84872652238
-
-
2012
-
www.physionet.org 2012.
-
-
-
-
31
-
-
0036790111
-
Heart rate variability in critical care medicine
-
Gang Y, Malik M. Heart rate variability in critical care medicine. Curr Opin Crit Care. 2002;8(5):371-5.
-
(2002)
Curr Opin Crit Care
, vol.8
, Issue.5
, pp. 371-375
-
-
Gang, Y.1
Malik, M.2
-
32
-
-
30444431610
-
Heart rate characteristics monitoring for neonatal sepsis
-
Moorman JR, Lake DE, Griffin MP. Heart rate characteristics monitoring for neonatal sepsis. IEEE Trans Biomed Eng 2006;53(1):126-32.
-
(2006)
IEEE Trans Biomed Eng
, vol.53
, Issue.1
, pp. 126-132
-
-
Moorman, J.R.1
Lake, D.E.2
Griffin, M.P.3
-
33
-
-
0029893535
-
Uncoupling of biological oscillators: A complementary hypothesis concerning the pathogenesis of multiple organ dysfunction syndrome
-
Godin PJ, Buchman TG. Uncoupling of biological oscillators: a complementary hypothesis concerning the pathogenesis of multiple organ dysfunction syndrome. Crit Care Med. 1996;24(7):1107-16.
-
(1996)
Crit Care Med
, vol.24
, Issue.7
, pp. 1107-1116
-
-
Godin, P.J.1
Buchman, T.G.2
-
34
-
-
0032778367
-
Inappropriate sympathetic activation at onset of septic shock: A spectral analysis approach
-
Annane D, Trabold F, Sharshar T, Jarrin I, Blanc AS, Raphael JC, Gajdos P. Inappropriate sympathetic activation at onset of septic shock: a spectral analysis approach. Am J Respir Crit Care Med. 1999;160(2):458-65.
-
(1999)
Am J Respir Crit Care Med
, vol.160
, Issue.2
, pp. 458-465
-
-
Annane, D.1
Trabold, F.2
Sharshar, T.3
Jarrin, I.4
Blanc, A.S.5
Raphael, J.C.6
Gajdos, P.7
-
35
-
-
0034948109
-
Cardiac variability in critically ill adults: Influence of sepsis
-
Korach M, Sharshar T, Jarrin I, Fouillot JP, Raphael JC, Gajdos P, Annane D. Cardiac variability in critically ill adults: influence of sepsis. Crit Care Med. 2001;29(7): 1380-5.
-
(2001)
Crit Care Med
, vol.29
, Issue.7
, pp. 1380-1385
-
-
Korach, M.1
Sharshar, T.2
Jarrin, I.3
Fouillot, J.P.4
Raphael, J.C.5
Gajdos, P.6
Annane, D.7
-
36
-
-
0028943513
-
Autonomic control of the heart and peripheral vessels in human septic shock
-
Piepoli M, Garrard CS, Kontoyannis DA, Bernardi L. Autonomic control of the heart and peripheral vessels in human septic shock. Intensive Care Med. 1995;21(2):112-9.
-
(1995)
Intensive Care Med
, vol.21
, Issue.2
, pp. 112-119
-
-
Piepoli, M.1
Garrard, C.S.2
Kontoyannis, D.A.3
Bernardi, L.4
-
37
-
-
70349616532
-
Endotoxin depresses heart rate variability in mice: Cytokine and steroid effects
-
Fairchild KD, Saucerman JJ, Raynor LL, Sivak JA, Xiao Y, Lake DE, Moorman JR. Endotoxin depresses heart rate variability in mice: cytokine and steroid effects. Am J Physiol Regul Integr Comp Physiol. 2009;297(4):R1019-27.
-
(2009)
Am J Physiol Regul Integr Comp Physiol
, vol.297
, Issue.4
-
-
Fairchild, K.D.1
Saucerman, J.J.2
Raynor, L.L.3
Sivak, J.A.4
Xiao, Y.5
Lake, D.E.6
Moorman, J.R.7
-
38
-
-
0029988782
-
Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology
-
Heart rate variability. Standards of measurement, physiological interpretation, and clinical use
-
Heart rate variability. Standards of measurement, physiological interpretation, and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Eur Heart J. 1996;17(3):354-81.
-
(1996)
Eur Heart J
, vol.17
, Issue.3
, pp. 354-381
-
-
-
40
-
-
0021912061
-
Assessment of autonomic function in humans by heart rate spectral analysis
-
Pomeranz B, Macaulay RJ, Caudill MA, Kutz I, Adam D, Gordon D, Kilborn KM, Barger AC, Shannon DC, Cohen RJ, Benson H. Assessment of autonomic function in humans by heart rate spectral analysis. Am.J Physiol. 1985;248(1 Pt 2):H151-H153.
-
(1985)
Am.J Physiol
, vol.248
, Issue.1 PART 2
-
-
Pomeranz, B.1
Macaulay, R.J.2
Caudill, M.A.3
Kutz, I.4
Adam, D.5
Gordon, D.6
Kilborn, K.M.7
Barger, A.C.8
Shannon, D.C.9
Cohen, R.J.10
Benson, H.11
-
41
-
-
0029979116
-
Experimental human endotoxemia increases cardiac regularity: Results from a prospective, randomized, crossover trial
-
Godin PJ, Fleisher LA, Eidsath A, Vandivier RW, Preas HL, Banks SM, Buchman TG, Suffredini AF. Experimental human endotoxemia increases cardiac regularity: results from a prospective, randomized, crossover trial. Crit Care Med. 1996;24(7):1117-24.
-
(1996)
Crit Care Med
, vol.24
, Issue.7
, pp. 1117-1124
-
-
Godin, P.J.1
Fleisher, L.A.2
Eidsath, A.3
Vandivier, R.W.4
Preas, H.L.5
Banks, S.M.6
Buchman, T.G.7
Suffredini, A.F.8
-
42
-
-
0036301884
-
Heart rate variability in emergency department patients with sepsis
-
Barnaby D, Ferrick K, Kaplan DT, Shah S, Bijur P, Gallagher EJ. Heart rate variability in emergency department patients with sepsis. Acad Emerg Med. 2002;9(7):661-70.
-
(2002)
Acad Emerg Med
, vol.9
, Issue.7
, pp. 661-670
-
-
Barnaby, D.1
Ferrick, K.2
Kaplan, D.T.3
Shah, S.4
Bijur, P.5
Gallagher, E.J.6
-
43
-
-
34247145917
-
Characteristics of heart rate variability can predict impending septic shock in emergency department patients with sepsis
-
Chen WL, Kuo CD. Characteristics of heart rate variability can predict impending septic shock in emergency department patients with sepsis. Acad Emerg Med. 2007;14(5):392-7.
-
(2007)
Acad Emerg Med
, vol.14
, Issue.5
, pp. 392-397
-
-
Chen, W.L.1
Kuo, C.D.2
-
44
-
-
0242609242
-
Heart rate variability as early marker of multiple organ dysfunction syndrome in septic patients
-
Pontet J, Contreras P, Curbelo A, Medina J, Noveri S, Bentancourt S, Migliaro ER. Heart rate variability as early marker of multiple organ dysfunction syndrome in septic patients. J Crit Care. 2003;18(3):156-63.
-
(2003)
J Crit Care
, vol.18
, Issue.3
, pp. 156-163
-
-
Pontet, J.1
Contreras, P.2
Curbelo, A.3
Medina, J.4
Noveri, S.5
Bentancourt, S.6
Migliaro, E.R.7
-
45
-
-
69949162508
-
Continuous multi-parameter heart rate variability analysis heralds onset of sepsis in adults
-
Ahmad S, Ramsay T, Huebsch L, Flanagan S, McDiarmid S, Batkin I, McIntyre L, Sundaresan SR, Maziak DE, Shamji FM, Hebert P, Fergusson D, Tinmouth A, Seely AJ. Continuous multi-parameter heart rate variability analysis heralds onset of sepsis in adults. PLoS ONE. 2009;4(8):e6642.
-
(2009)
PLoS ONE
, vol.4
, Issue.8
-
-
Ahmad, S.1
Ramsay, T.2
Huebsch, L.3
Flanagan, S.4
McDiarmid, S.5
Batkin, I.6
McIntyre, L.7
Sundaresan, S.R.8
Maziak, D.E.9
Shamji, F.M.10
Hebert, P.11
Fergusson, D.12
Tinmouth, A.13
Seely, A.J.14
-
46
-
-
77449121950
-
Bench-to-bedside review: Ventilatory abnormalities in sepsis
-
Magder S. Bench-to-bedside review: ventilatory abnormalities in sepsis. Crit Care 2009;13(1):202-13.
-
(2009)
Crit Care
, vol.13
, Issue.1
, pp. 202-213
-
-
Magder, S.1
-
47
-
-
0035880864
-
Effect of endotoxin on ventilation and breath variability: Role of cyclooxygenase pathway
-
Preas HL, Jubran A, Vandivier RW, Reda D, Godin PJ, Banks SM, Tobin MJ, Suffredini AF. Effect of endotoxin on ventilation and breath variability: role of cyclooxygenase pathway. Am J Respir.Crit Care Med. 2001;164(4):620-6.
-
(2001)
Am J Respir.Crit Care Med
, vol.164
, Issue.4
, pp. 620-626
-
-
Preas, H.L.1
Jubran, A.2
Vandivier, R.W.3
Reda, D.4
Godin, P.J.5
Banks, S.M.6
Tobin, M.J.7
Suffredini, A.F.8
-
48
-
-
67650609140
-
Heart-rate complexity for prediction of prehospital lifesaving interventions in trauma patients
-
Cancio LC, Batchinsky AI, Salinas J, Kuusela T, Convertino VA, Wade CE, Holcomb JB. Heart-rate complexity for prediction of prehospital lifesaving interventions in trauma patients. J Trauma. 2008;65(4):813-9.
-
(2008)
J Trauma
, vol.65
, Issue.4
, pp. 813-819
-
-
Cancio, L.C.1
Batchinsky, A.I.2
Salinas, J.3
Kuusela, T.4
Convertino, V.A.5
Wade, C.E.6
Holcomb, J.B.7
-
49
-
-
84872659215
-
-
www.iccai.org/sci_info_2010.php.
-
-
-
-
50
-
-
29744451770
-
Phenomenological issues related to the measurement, mechanisms and manipulation of complex biological systems
-
An G. Phenomenological issues related to the measurement, mechanisms and manipulation of complex biological systems. Crit Care Med. 2006;34(1):245-6.
-
(2006)
Crit Care Med
, vol.34
, Issue.1
, pp. 245-246
-
-
An, G.1
-
51
-
-
48249115932
-
The epidemiology of sepsis
-
Hodgin KE, Moss M. The epidemiology of sepsis. Curr Pharm Des. 2008;14(19):1833-9.
-
(2008)
Curr Pharm Des
, vol.14
, Issue.19
, pp. 1833-1839
-
-
Hodgin, K.E.1
Moss, M.2
-
53
-
-
2942678943
-
Injury research in the genomic era
-
Cobb JP, O'Keefe GE. Injury research in the genomic era. Lancet. 2004;363(9426):2076-83.
-
(2004)
Lancet
, vol.363
, Issue.9426
, pp. 2076-2083
-
-
Cobb, J.P.1
O'Keefe, G.E.2
-
54
-
-
33846069325
-
Microarray-based analysis of ventilator-induced lung injury
-
Wurfel MM. Microarray-based analysis of ventilator-induced lung injury. Proc Am Thorac Soc. 2007;4(1):77-84.
-
(2007)
Proc Am Thorac Soc
, vol.4
, Issue.1
, pp. 77-84
-
-
Wurfel, M.M.1
-
55
-
-
42049098847
-
Inflammation and genomics in the critical care unit
-
Winkelman C. Inflammation and genomics in the critical care unit. Crit Care Nurs Clin North Am. 2008;20(2):213-21+vi.
-
(2008)
Crit Care Nurs Clin North Am
, vol.20
, Issue.2
-
-
Winkelman, C.1
-
56
-
-
0037251105
-
Proteomics and systems biology approaches to signal transduction in sepsis
-
Nguyen A, Yaffe MB. Proteomics and systems biology approaches to signal transduction in sepsis. Crit Care Med. 2003;31(1 suppl):S1-6
-
(2003)
Crit Care Med
, vol.31
, Issue.SUPPL.
-
-
Nguyen, A.1
Yaffe, M.B.2
-
57
-
-
77955551852
-
Molecular diagnostics of sepsis-where are we today?
-
Bauer M, Reinhart K. Molecular diagnostics of sepsis-where are we today? Int J Med Microbiol. 2010;300(6):411-3.
-
(2010)
Int J Med Microbiol
, vol.300
, Issue.6
, pp. 411-413
-
-
Bauer, M.1
Reinhart, K.2
-
58
-
-
80052922354
-
The Emerging Field of Quantitative Blood Metabolomics for Biomarker Discovery in Critical Illnesses
-
Sep 15
-
Serkova NJ, Standiford TJ, Stringer KA. The Emerging Field of Quantitative Blood Metabolomics for Biomarker Discovery in Critical Illnesses. Am J Respir Crit Care Med. 2011;Sep 15;184(6):647-55.
-
(2011)
Am J Respir Crit Care Med
, vol.184
, Issue.6
, pp. 647-655
-
-
Serkova, N.J.1
Standiford, T.J.2
Stringer, K.A.3
-
59
-
-
27144509163
-
Large Scale Collab
-
Calvano SE, Xiao W, Richards DR, Felciano RM, Baker HV, Cho RJ, Chen RO, Brownstein BH, Cobb JP, Tschoeke SK, Miller-Graziano C, Moldawer LL, Mindrinos MN, Davis RW, Tompkins RG, Lowry SF, Large Scale Collab Res Program. A network-based analysis of systemic inflammation in humans. Nature. 2005;437:1032-7.
-
(2005)
Res Program. a Network-based Analysis of Systemic Inflammation In Humans. Nature
, vol.437
, pp. 1032-1037
-
-
Calvano, S.E.1
Xiao, W.2
Richards, D.R.3
Felciano, R.M.4
Baker, H.V.5
Cho, R.J.6
Chen, R.O.7
Brownstein, B.H.8
Cobb, J.P.9
Tschoeke, S.K.10
Miller-Graziano, C.11
Moldawer, L.L.12
Mindrinos, M.N.13
Davis, R.W.14
Tompkins, R.G.15
Lowry, S.F.16
-
60
-
-
33750629023
-
High dynamic range characterization of the trauma patient plasma proteome
-
Liu T, Qian WJ, Gritsenko MA, Xiao W, Moldawer LL, Kaushal A, Monroe ME, Varnum SM, Moore RJ, Purvine SO, Maier RV, Davis RW, Tompkins RG, Camp DG, Smith RD. High dynamic range characterization of the trauma patient plasma proteome. Mol Cell Proteomics. 2006;5(10):1899-913.
-
(2006)
Mol Cell Proteomics
, vol.5
, Issue.10
, pp. 1899-1913
-
-
Liu, T.1
Qian, W.J.2
Gritsenko, M.A.3
Xiao, W.4
Moldawer, L.L.5
Kaushal, A.6
Monroe, M.E.7
Varnum, S.M.8
Moore, R.J.9
Purvine, S.O.10
Maier, R.V.11
Davis, R.W.12
Tompkins, R.G.13
Camp, D.G.14
Smith, R.D.15
-
61
-
-
45349102367
-
Plasticity of the systemic inflammatory response to acute infection during critical illness: Development of the riboleukogram
-
McDunn JE, Husain KD, Polpitiya AD, Burykin A, Ruan J, Li Q, Schierding W, Lin N, Dixon D, Zhang W, Coopersmith CM, Dunne WM, Colonna M, Ghosh BK, Cobb JP. Plasticity of the systemic inflammatory response to acute infection during critical illness: development of the riboleukogram. PLoS ONE. 2008;3(2): e1564.
-
(2008)
PLoS ONE
, vol.3
, Issue.2
-
-
McDunn, J.E.1
Husain, K.D.2
Polpitiya, A.D.3
Burykin, A.4
Ruan, J.5
Li, Q.6
Schierding, W.7
Lin, N.8
Dixon, D.9
Zhang, W.10
Coopersmith, C.M.11
Dunne, W.M.12
Colonna, M.13
Ghosh, B.K.14
Cobb, J.P.15
-
62
-
-
67650508418
-
A genomic score prognostic of outcome in trauma patients
-
Warren HS, Elson CM, Hayden DL, Schoenfeld DA, Cobb JP, Maier RV, Moldawer LL, Moore EE, Harbrecht BG, Pelak K, Cuschieri J, Herndon DN, Jeschke MG, Finnerty CC, Brownstein BH, Hennessy L, Mason PH, Tompkins RG. A genomic score prognostic of outcome in trauma patients. Mol Med. 2009;15(7-8):220-7.
-
(2009)
Mol Med
, vol.15
, Issue.7-8
, pp. 220-227
-
-
Warren, H.S.1
Elson, C.M.2
Hayden, D.L.3
Schoenfeld, D.A.4
Cobb, J.P.5
Maier, R.V.6
Moldawer, L.L.7
Moore, E.E.8
Harbrecht, B.G.9
Pelak, K.10
Cuschieri, J.11
Herndon, D.N.12
Jeschke, M.G.13
Finnerty, C.C.14
Brownstein, B.H.15
Hennessy, L.16
Mason, P.H.17
Tompkins, R.G.18
-
63
-
-
70349669015
-
Validation of the riboleukogram to detect ventilator-associated pneumonia after severe injury
-
Cobb JP, Moore EE, Hayden DL, Minei JP, Cuschieri J, Yang J, Li Q, Lin N, Brownstein BH, Hennessy L, Mason PH, Schierding WS, Dixon DJ, Tompkins RG, Warren HS, Schoenfeld DA, Maier RV. Validation of the riboleukogram to detect ventilator-associated pneumonia after severe injury. Ann Surg. 2009;250(4):531-9.
-
(2009)
Ann Surg
, vol.250
, Issue.4
, pp. 531-539
-
-
Cobb, J.P.1
Moore, E.E.2
Hayden, D.L.3
Minei, J.P.4
Cuschieri, J.5
Yang, J.6
Li, Q.7
Lin, N.8
Brownstein, B.H.9
Hennessy, L.10
Mason, P.H.11
Schierding, W.S.12
Dixon, D.J.13
Tompkins, R.G.14
Warren, H.S.15
Schoenfeld, D.A.16
Maier, R.V.17
-
64
-
-
77956330708
-
Plasma proteome response to severe burn injury revealed by 180-labeled universal reference-based quantitative proteomics
-
Qian WJ, Petritis BO, Kaushal A, Finnerty CC, Jeschke MG, Monroe ME, Moore RJ, Schepmoes AA, Xiao W, Moldawer LL, Davis RW, Tompkins RG, Herndon DN, Camp DG, Smith RD. Plasma proteome response to severe burn injury revealed by 180-labeled universal reference-based quantitative proteomics. J Proteome Res. 2010;9(9):4779-89.
-
(2010)
J Proteome Res
, vol.9
, Issue.9
, pp. 4779-4789
-
-
Qian, W.J.1
Petritis, B.O.2
Kaushal, A.3
Finnerty, C.C.4
Jeschke, M.G.5
Monroe, M.E.6
Moore, R.J.7
Schepmoes, A.A.8
Xiao, W.9
Moldawer, L.L.10
Davis, R.W.11
Tompkins, R.G.12
Herndon, D.N.13
Camp, D.G.14
Smith, R.D.15
-
65
-
-
77953426735
-
Analysis of factorial time-course microarrays with application to a clinical study of burn injury
-
Zhou B, Xu W, Herndon D, Tompkins R, Davis R, Xiao W, Wong WH, Toner M, Warren HS, Schoenfeld DA, Rahme L, McDonald-Smith GP, Hayden D, Mason P, Fagan S, Yu YM, Cobb JP, Remick DG, Mannick JA, Lederer JA, Gamelli RL, Silver GM, West MA, Shapiro MB, Smith R, Camp DG, Qian W, Storey J, Mindrinos M, Tibshirani R, Lowry S, Calvano S, Chaudry I, West MA, Cohen M, Moore EE, Johnson J, Moldawer LL, Baker HV, Efron PA, Balis UG, Billiar TR, Ochoa JB, Sperry JL, Miller-Graziano CL, De AK, Bankey PE, Finnerty CC, Jeschke MG, Minei JP, Arnoldo BD, Hunt JL, Horton J, Cobb JP, Brownstein B, Freeman B, Maier RV, Nathens AB, Cuschieri J, Gibran N, Klein M, O'keefe G. Analysis of factorial time-course microarrays with application to a clinical study of burn injury. Proc Natl Acad Sci U S A. 2010;107(22):9923-8.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.22
, pp. 9923-9928
-
-
Zhou, B.1
Xu, W.2
Herndon, D.3
Tompkins, R.4
Davis, R.5
Xiao, W.6
Wong, W.H.7
Toner, M.8
Warren, H.S.9
Schoenfeld, D.A.10
Rahme, L.11
McDonald-Smith, G.P.12
Hayden, D.13
Mason, P.14
Fagan, S.15
Yu, Y.M.16
Cobb, J.P.17
Remick, D.G.18
Mannick, J.A.19
Lederer, J.A.20
Gamelli, R.L.21
Silver, G.M.22
West, M.A.23
Shapiro, M.B.24
Smith, R.25
Camp, D.G.26
Qian, W.27
Storey, J.28
Mindrinos, M.29
Tibshirani, R.30
Lowry, S.31
Calvano, S.32
Chaudry, I.33
West, M.A.34
Cohen, M.35
Moore, E.E.36
Johnson, J.37
Moldawer, L.L.38
Baker, H.V.39
Efron, P.A.40
Balis, U.G.41
Billiar, T.R.42
Ochoa, J.B.43
Sperry, J.L.44
Miller-Graziano, C.L.45
De, A.K.46
Bankey, P.E.47
Finnerty, C.C.48
Jeschke, M.G.49
Minei, J.P.50
Arnoldo, B.D.51
Hunt, J.L.52
Horton, J.53
Cobb, J.P.54
Brownstein, B.55
Freeman, B.56
Maier, R.V.57
Nathens, A.B.58
Cuschieri, J.59
Gibran, N.60
Klein, M.61
O'Keefe, G.62
more..
-
66
-
-
79955904927
-
A dynamic view of trauma/hemorrhageinduced inflammation in mice: Principal drivers and networks
-
Mi Q, Constantine G, Ziraldo C, Solovyev A, Torres A, Namas R, Bentley T, Billiar TR, Zamora R, Puyana JC, Vodovotz Y. A dynamic view of trauma/hemorrhageinduced inflammation in mice: Principal drivers and networks. PLoS ONE. 2011;6:e19424.
-
(2011)
PLoS ONE
, vol.6
-
-
Mi, Q.1
Constantine, G.2
Ziraldo, C.3
Solovyev, A.4
Torres, A.5
Namas, R.6
Bentley, T.7
Billiar, T.R.8
Zamora, R.9
Puyana, J.C.10
Vodovotz, Y.11
-
67
-
-
43249089766
-
Translational systems biology of inflammation
-
Vodovotz Y, Csete M, Bartels J, Chang S, An G. Translational systems biology of inflammation. PLoS Comput Biol. 2008;4:1-6.
-
(2008)
PLoS Comput Biol
, vol.4
, pp. 1-6
-
-
Vodovotz, Y.1
Csete, M.2
Bartels, J.3
Chang, S.4
An, G.5
-
68
-
-
71749089391
-
Networks, biology and systems engineering: A case study in inflammation
-
Foteinou PT, Yang E, Androulakis IP. Networks, biology and systems engineering: a case study in inflammation. Comput Chem Eng. 2009;33(12):2028-41.
-
(2009)
Comput Chem Eng
, vol.33
, Issue.12
, pp. 2028-2041
-
-
Foteinou, P.T.1
Yang, E.2
Androulakis, I.P.3
-
69
-
-
71749110416
-
Translational potential of systems-based models of inflammation
-
Foteinou PT, Calvano SE, Lowry SF, Androulakis IP. Translational potential of systems-based models of inflammation. Clin Transl Sci. 2009;2(1):85-9.
-
(2009)
Clin Transl Sci
, vol.2
, Issue.1
, pp. 85-89
-
-
Foteinou, P.T.1
Calvano, S.E.2
Lowry, S.F.3
Androulakis, I.P.4
-
70
-
-
57749172576
-
Mechanistic simulations of inflammation: Current state and future prospects
-
Vodovotz Y, Constantine G, Rubin J, Csete M, Voit EO, An G. Mechanistic simulations of inflammation: Current state and future prospects. Math Biosci. 2009;217:1-10.
-
(2009)
Math Biosci
, vol.217
, pp. 1-10
-
-
Vodovotz, Y.1
Constantine, G.2
Rubin, J.3
Csete, M.4
Voit, E.O.5
An, G.6
-
72
-
-
77952163906
-
Translational systems approaches to the biology of inflammation and healing
-
Vodovotz Y, Constantine G, Faeder J, Mi Q, Rubin J, Sarkar J, Squires R, Okonkwo DO, Gerlach J, Zamora R, Luckhart S, Ermentrout B, An G. Translational systems approaches to the biology of inflammation and healing. Immunopharmacol Immunotoxicol. 2010;32:181-95.
-
(2010)
Immunopharmacol Immunotoxicol
, vol.32
, pp. 181-195
-
-
Vodovotz, Y.1
Constantine, G.2
Faeder, J.3
Mi, Q.4
Rubin, J.5
Sarkar, J.6
Squires, R.7
Okonkwo, D.O.8
Gerlach, J.9
Zamora, R.10
Luckhart, S.11
Ermentrout, B.12
An, G.13
-
73
-
-
74549170381
-
Translational systems biology of inflammation and healing
-
Vodovotz Y. Translational systems biology of inflammation and healing. Wound Repair Regen. 2010;18(1):3-7.
-
(2010)
Wound Repair Regen
, vol.18
, Issue.1
, pp. 3-7
-
-
Vodovotz, Y.1
-
74
-
-
77957580213
-
Translational systems biology of inflammation: Potential applications to personalized medicine
-
Mi Q, Li NYK, Ziraldo C, Ghuma A, Mikheev M, Squires R, Okonkwo DO, Verdolini Abbott K, Constantine G, An G, Vodovotz Y. Translational systems biology of inflammation: Potential applications to personalized medicine. Personalized Med. 2010;7:549-59.
-
(2010)
Personalized Med
, vol.7
, pp. 549-559
-
-
Mi, Q.1
Li, N.Y.K.2
Ziraldo, C.3
Ghuma, A.4
Mikheev, M.5
Squires, R.6
Okonkwo, D.O.7
Verdolini Abbott, K.8
Constantine, G.9
An, G.10
Vodovotz, Y.11
-
77
-
-
59649117667
-
Molecular biology of inflammation and sepsis: A primer
-
Cinel I, Opal SM. Molecular biology of inflammation and sepsis: a primer. Crit Care Med. 2009;37(1):291-304.
-
(2009)
Crit Care Med
, vol.37
, Issue.1
, pp. 291-304
-
-
Cinel, I.1
Opal, S.M.2
-
78
-
-
33747341838
-
In silico models of acute inflammation in animals
-
Vodovotz Y, Chow CC, Bartels J, Lagoa C, Prince JM, Levy RM, Kumar R, Day J, Rubin J, Constantine G, Billiar TR, Fink MP, Clermont G. In silico models of acute inflammation in animals. Shock. 2006;26(3):235-44.
-
(2006)
Shock
, vol.26
, Issue.3
, pp. 235-244
-
-
Vodovotz, Y.1
Chow, C.C.2
Bartels, J.3
Lagoa, C.4
Prince, J.M.5
Levy, R.M.6
Kumar, R.7
Day, J.8
Rubin, J.9
Constantine, G.10
Billiar, T.R.11
Fink, M.P.12
Clermont, G.13
-
79
-
-
77957580213
-
Translational systems biology of inflammation: Potential applications to personalized medicine
-
Mi Q, Li NYK, Ziraldo C, Ghuma A, Mikheev M, Squires R, Okonkwo DO, Verdolini Abbott K, Constantine G, An G, Vodovotz Y. Translational systems biology of inflammation: Potential applications to personalized medicine. Personalized Med. 2010;7:549-59.
-
(2010)
Personalized Med
, vol.7
, pp. 549-559
-
-
Mi, Q.1
Li, N.Y.K.2
Ziraldo, C.3
Ghuma, A.4
Mikheev, M.5
Squires, R.6
Okonkwo, D.O.7
Verdolini Abbott, K.8
Constantine, G.9
An, G.10
Vodovotz, Y.11
-
80
-
-
77949531330
-
An adequately robust early TNF-alpha; response is a hallmark of survival following trauma/hemorrhage
-
Namas R, Ghuma A, Torres A, Polanco P, Gomez H, Barclay D, Gordon L, Zenker S, Kim HK, Hermus L, Zamora R, Rosengart MR, Clermont G, Peitzman A, Billiar TR, Ochoa J, Pinsky MR, Puyana JC, Vodovotz Y. An adequately robust early TNF-α response is a hallmark of survival following trauma/hemorrhage. PLoS ONE. 2009;4(12):e8406.
-
(2009)
PLoS ONE
, vol.4
, Issue.12
-
-
Namas, R.1
Ghuma, A.2
Torres, A.3
Polanco, P.4
Gomez, H.5
Barclay, D.6
Gordon, L.7
Zenker, S.8
Kim, H.K.9
Hermus, L.10
Zamora, R.11
Rosengart, M.R.12
Clermont, G.13
Peitzman, A.14
Billiar, T.R.15
Ochoa, J.16
Pinsky, M.R.17
Puyana, J.C.18
Vodovotz, Y.19
-
81
-
-
0031657908
-
Mediators in polytrauma-pathophysiological significance and clinical relevance
-
Rose S, Marzi I. Mediators in polytrauma-pathophysiological significance and clinical relevance. Langenbecks Arch Surg. 1998;383(3-4):199-208.
-
(1998)
Langenbecks Arch Surg
, vol.383
, Issue.3-4
, pp. 199-208
-
-
Rose, S.1
Marzi, I.2
-
82
-
-
0031709519
-
Trauma and the immune response
-
Smith RM, Giannoudis PV. Trauma and the immune response. J.R.Soc.Med. 1998;91(8):417-20.
-
(1998)
J.R.Soc.Med
, vol.91
, Issue.8
, pp. 417-420
-
-
Smith, R.M.1
Giannoudis, P.V.2
-
83
-
-
0037426726
-
The pathophysiology and treatment of sepsis
-
Hotchkiss RS, Karl IE. The pathophysiology and treatment of sepsis. N Engl J Med. 2003;348(2):138-50.
-
(2003)
N Engl J Med
, vol.348
, Issue.2
, pp. 138-150
-
-
Hotchkiss, R.S.1
Karl, I.E.2
-
84
-
-
15244341423
-
Epithelial barrier dysfunction: A unifying theme to explain the pathogenesis of multiple organ dysfunction at the cellular level
-
Fink MP, Delude RL. Epithelial barrier dysfunction: a unifying theme to explain the pathogenesis of multiple organ dysfunction at the cellular level. Crit Care Clin. 2005;21(2):177-96.
-
(2005)
Crit Care Clin
, vol.21
, Issue.2
, pp. 177-196
-
-
Fink, M.P.1
Delude, R.L.2
-
85
-
-
0034919862
-
Inflammation, coagulopathy, and the pathogenesis of multiple organ dysfunction syndrome
-
Marshall JC. Inflammation, coagulopathy, and the pathogenesis of multiple organ dysfunction syndrome. Crit Care Med. 2001;29(7 suppl):S99-106.
-
(2001)
Crit Care Med
, vol.29
, Issue.7 SUPPL.
-
-
Marshall, J.C.1
-
86
-
-
0033258418
-
Organ dysfunction following hemorrhage and sepsis: Mechanisms and therapeutic approaches (Review)
-
Jarrar D, Chaudry IH, Wang P. Organ dysfunction following hemorrhage and sepsis: mechanisms and therapeutic approaches (Review). Int J Mol Med. 1999;4(6):575-83.
-
(1999)
Int J Mol Med
, vol.4
, Issue.6
, pp. 575-583
-
-
Jarrar, D.1
Chaudry, I.H.2
Wang, P.3
-
87
-
-
48249138990
-
Sepsis: Links between pathogen sensing and organ damage
-
Crouser E, Exline M, Knoell D, Wewers MD. Sepsis: links between pathogen sensing and organ damage. Curr. Pharm.Des 2008;14(19):1840-52.
-
(2008)
Curr. Pharm.Des
, vol.14
, Issue.19
, pp. 1840-1852
-
-
Crouser, E.1
Exline, M.2
Knoell, D.3
Wewers, M.D.4
-
88
-
-
0029784526
-
Why sepsis trials fail
-
Bone RC. Why sepsis trials fail. JAMA.1996;276(7):565-6.
-
(1996)
JAMA
, vol.276
, Issue.7
, pp. 565-566
-
-
Bone, R.C.1
-
89
-
-
4744342992
-
Mathematical models of the acute inflammatory response
-
Vodovotz Y, Clermont G, Chow C, An G. Mathematical models of the acute inflammatory response. Curr.Opin. Crit Care. 2004;10(5):383-90.
-
(2004)
Curr.Opin Crit Care
, vol.10
, Issue.5
, pp. 383-390
-
-
Vodovotz, Y.1
Clermont, G.2
Chow, C.3
An, G.4
-
90
-
-
0035486687
-
Complexity and non-linearity in shock research: Reductionism or synthesis?
-
Neugebauer E., Willy C, Sauerland S. Complexity and non-linearity in shock research: reductionism or synthesis? Shock. 2001;16(4):252-8.
-
(2001)
Shock
, vol.16
, Issue.4
, pp. 252-258
-
-
Neugebauer, E.1
Willy, C.2
Sauerland, S.3
-
91
-
-
0036363170
-
Sepsis research in the next millennium: Concentrate on the software rather than the hardware
-
Tjardes T, Neugebauer E. Sepsis research in the next millennium: concentrate on the software rather than the hardware. Shock. 2002;17(1):1-8.
-
(2002)
Shock
, vol.17
, Issue.1
, pp. 1-8
-
-
Tjardes, T.1
Neugebauer, E.2
-
92
-
-
0035489972
-
Complex systems analysis: A tool for shock research
-
Buchman TG, Cobb JP, Lapedes AS, Kepler TB. Complex systems analysis: a tool for shock research. Shock. 2001;16(4):248-51.
-
(2001)
Shock
, vol.16
, Issue.4
, pp. 248-251
-
-
Buchman, T.G.1
Cobb, J.P.2
Lapedes, A.S.3
Kepler, T.B.4
-
93
-
-
0033866133
-
Multiple organ dysfunction syndrome: Exploring the paradigm of complex nonlinear systems
-
Seely AJ, Christou NV. Multiple organ dysfunction syndrome: exploring the paradigm of complex nonlinear systems. Crit Care Med. 2000;28(7):2193-200.
-
(2000)
Crit Care Med
, vol.28
, Issue.7
, pp. 2193-2200
-
-
Seely, A.J.1
Christou, N.V.2
-
94
-
-
0035491584
-
Agent-based computer simulation and sirs: Building a bridge between basic science and clinical trials
-
An G. Agent-based computer simulation and sirs: building a bridge between basic science and clinical trials. Shock. 2001;16(4):266-73.
-
(2001)
Shock
, vol.16
, Issue.4
, pp. 266-273
-
-
An, G.1
-
95
-
-
0036500993
-
Systems biology: A brief overview
-
Kitano H. Systems biology: a brief overview. Science. 2002;295(5560):1662-4.
-
(2002)
Science
, vol.295
, Issue.5560
, pp. 1662-1664
-
-
Kitano, H.1
-
96
-
-
43249089766
-
Translational systems biology of inflammation
-
Vodovotz Y, Csete M, Bartels J, Chang S, An G. Translational systems biology of inflammation. PLoS Comput Biol. 2008;4(4):e1000014
-
(2008)
PLoS Comput Biol
, vol.4
, Issue.4
-
-
Vodovotz, Y.1
Csete, M.2
Bartels, J.3
Chang, S.4
An, G.5
-
97
-
-
77956642489
-
Identification of complex metabolic states in critically injured patients using bioinformatic cluster analysis
-
Cohen MJ, Grossman AD, Morabito D, Knudson MM, Butte AJ, Manley GT. Identification of complex metabolic states in critically injured patients using bioinformatic cluster analysis. Crit Care. 2010;14(1):R10-20.
-
(2010)
Crit Care
, vol.14
, Issue.1
-
-
Cohen, M.J.1
Grossman, A.D.2
Morabito, D.3
Knudson, M.M.4
Butte, A.J.5
Manley, G.T.6
-
98
-
-
4744344132
-
In-silico experiments of existing and hypothetical cytokine-directed clinical trials using agent based modeling
-
An G. In-silico experiments of existing and hypothetical cytokine-directed clinical trials using agent based modeling. Crit Care Med. 2004;32:2050-60.
-
(2004)
Crit Care Med
, vol.32
, pp. 2050-2060
-
-
An, G.1
-
99
-
-
33947181077
-
Deciphering the complexity of acute inflammation using mathematical models
-
Vodovotz Y. Deciphering the complexity of acute inflammation using mathematical models. Immunol Res. 2006;36(1-3):237-45.
-
(2006)
Immunol Res
, vol.36
, Issue.1-3
, pp. 237-245
-
-
Vodovotz, Y.1
-
100
-
-
84872672653
-
-
http://commonfund.nih.gov/aboutroadmap.aspx.
-
-
-
-
101
-
-
74549209507
-
Translational systems biology using an agent based approach for dynamic knowledge representation
-
An G. Translational systems biology using an agent based approach for dynamic knowledge representation: An evolutionary paradigm for biomedical research. Wound Rep Reg. 2010;18:8-12.
-
(2010)
An Evolutionary Paradigm For Biomedical Research. Wound Rep Reg
, vol.18
, pp. 8-12
-
-
An, G.1
-
102
-
-
77955634106
-
Closing the scientific loop: Bridging correlation and causality in the petaflop age
-
41ps34
-
An G. Closing the scientific loop: Bridging correlation and causality in the petaflop age. Sci Transl Med. 2010;2:41ps34.
-
(2010)
Sci Transl Med
, vol.2
-
-
An, G.1
-
103
-
-
33947193958
-
Evidence-based modeling of critical illness: An initial consensus from the Society for Complexity in Acute Illness
-
Vodovotz Y, Clermont G, Hunt CA, Lefering R, Bartels J, Seydel R, Hotchkiss J, Ta'asan S, Neugebauer E, An G. Evidence-based modeling of critical illness: an initial consensus from the Society for Complexity in Acute Illness. J Crit Care. 2007;22(1):77-84.
-
(2007)
J Crit Care
, vol.22
, Issue.1
, pp. 77-84
-
-
Vodovotz, Y.1
Clermont, G.2
Hunt, C.A.3
Lefering, R.4
Bartels, J.5
Seydel, R.6
Hotchkiss, J.7
Ta'asan, S.8
Neugebauer, E.9
An, G.10
-
104
-
-
41849114552
-
Translational systems biology: Introduction of an engineering approach to the pathophysiology of the burn patient
-
An G, Faeder J, Vodovotz Y. Translational systems biology: Introduction of an engineering approach to the pathophysiology of the burn patient. J Burn Care Res. 2008;29:277-85.
-
(2008)
J Burn Care Res
, vol.29
, pp. 277-285
-
-
An, G.1
Faeder, J.2
Vodovotz, Y.3
-
105
-
-
79952117970
-
Agent-based models in translational systems biology
-
An G, Mi Q, Dutta-Moscato J, Solovyev A, Vodovotz Y. Agent-based models in translational systems biology. WIRES. 2009;1:159-71.
-
(2009)
WIRES
, vol.1
, pp. 159-171
-
-
An, G.1
Mi, Q.2
Dutta-Moscato, J.3
Solovyev, A.4
Vodovotz, Y.5
-
107
-
-
57849158644
-
Detailed qualitative dynamic knowledge representation using a BioNetGen model of TLR-4 signaling and preconditioning
-
An G, Faeder JR. Detailed qualitative dynamic knowledge representation using a BioNetGen model of TLR-4 signaling and preconditioning. Math Biosci. 2009;217:53-63.
-
(2009)
Math Biosci
, vol.217
, pp. 53-63
-
-
An, G.1
Faeder, J.R.2
-
108
-
-
57849103868
-
A model of TLR4 signaling and tolerance using a qualitative, particle event-based method:Introduction of Spatially Configured Stochastic Reaction Chambers (SCSRC)
-
An G. A model of TLR4 signaling and tolerance using a qualitative, particle event-based method: Introduction of Spatially Configured Stochastic Reaction Chambers (SCSRC). Math Biosci. 2009;217:43-52.
-
(2009)
Math Biosci
, vol.217
, pp. 43-52
-
-
An, G.1
-
109
-
-
0034677755
-
Mechanism-based target identification and drug discovery in cancer research
-
Gibbs JB. Mechanism-based target identification and drug discovery in cancer research. Science. 2000;287(5460): 1969-73.
-
(2000)
Science
, vol.287
, Issue.5460
, pp. 1969-1973
-
-
Gibbs, J.B.1
-
110
-
-
0037378771
-
Investigation of early events in Fc epsilon RI-mediated signaling using a detailed mathematical model
-
Faeder JR, Hlavacek WS, Reischl I, Blinov ML, Metzger H, Redondo A, Wofsy C, Goldstein B. Investigation of early events in Fc epsilon RI-mediated signaling using a detailed mathematical model. J Immunol. 2003;170(7):3769-81.
-
(2003)
J Immunol
, vol.170
, Issue.7
, pp. 3769-3781
-
-
Faeder, J.R.1
Hlavacek, W.S.2
Reischl, I.3
Blinov, M.L.4
Metzger, H.5
Redondo, A.6
Wofsy, C.7
Goldstein, B.8
-
111
-
-
57749186048
-
A simple mathematical model of signaling resulting from the binding of lipopolysaccharide with toll-like receptor 4 demonstrates inherent preconditioning behavior
-
Rivière B, Epshteyn Y, Swigon D, Vodovotz Y. A simple mathematical model of signaling resulting from the binding of lipopolysaccharide with toll-like receptor 4 demonstrates inherent preconditioning behavior. Math Biosci. 2009;217:19-26.
-
(2009)
Math Biosci
, vol.217
, pp. 19-26
-
-
Rivière, B.1
Epshteyn, Y.2
Swigon, D.3
Vodovotz, Y.4
-
112
-
-
21744440089
-
The acute inflammatory response in diverse shock states
-
Chow CC, Clermont G, Kumar R, Lagoa C, Tawadrous Z, Gallo D, Betten B, Bartels J, Constantine G, Fink MP, Billiar TR, Vodovotz Y. The acute inflammatory response in diverse shock states. Shock. 2005;24:74-84.
-
(2005)
Shock
, vol.24
, pp. 74-84
-
-
Chow, C.C.1
Clermont, G.2
Kumar, R.3
Lagoa, C.4
Tawadrous, Z.5
Gallo, D.6
Betten, B.7
Bartels, J.8
Constantine, G.9
Fink, M.P.10
Billiar, T.R.11
Vodovotz, Y.12
-
113
-
-
33747106908
-
A reduced mathematical model of the acute inflammatory response: I Derivation of model and analysis of anti-inflammation
-
Reynolds A, Rubin J, Clermont G, Day J, Vodovotz Y, Ermentrout GB. A reduced mathematical model of the acute inflammatory response: I Derivation of model and analysis of anti-inflammation. J Theor Biol. 2006;242:220-36.
-
(2006)
J Theor Biol
, vol.242
, pp. 220-236
-
-
Reynolds, A.1
Rubin, J.2
Clermont, G.3
Day, J.4
Vodovotz, Y.5
Ermentrout, G.B.6
-
114
-
-
33747094446
-
Reduced mathematical model of the acute inflammatory response II. Capturing scenarios of repeated endotoxin administration
-
Day J, Rubin J, Vodovotz Y, Chow CC, Reynolds A, Clermont G. A reduced mathematical model of the acute inflammatory response II. Capturing scenarios of repeated endotoxin administration: J Theor Biol. 2006;242:237-56.
-
(2006)
J Theor Biol
, vol.242
, pp. 237-256
-
-
Day, J.1
Rubin, J.2
Vodovotz, Y.3
Chow, C.C.4
Reynolds, A.5
Clermont, G.A.6
-
115
-
-
67749139592
-
Mathematical modeling of post-hemorrhage inflammation in mice Studies using a novel, computercontrolled, closed-loop hemorrhage apparatus
-
Torres A, Bentley T, Bartels J, Sarkar J, Barclay D, Namas R, Constantine G, Zamora R, Puyana JC, Vodovotz Y. Mathematical modeling of post-hemorrhage inflammation in mice Studies using a novel, computercontrolled, closed-loop hemorrhage apparatus. Shock 2009;32:172-8.
-
(2009)
Shock
, vol.32
, pp. 172-178
-
-
Torres, A.1
Bentley, T.2
Bartels, J.3
Sarkar, J.4
Barclay, D.5
Namas, R.6
Constantine, G.7
Zamora, R.8
Puyana, J.C.9
Vodovotz, Y.10
-
116
-
-
57849104348
-
Modeling endotoxin-induced systemic inflammation using an indirect response approach
-
Foteinou PT, Calvano SE, Lowry SF, Androulakis IP. Modeling endotoxin-induced systemic inflammation using an indirect response approach. Math Biosci. 2009;217:27-42.
-
(2009)
Math Biosci
, vol.217
, pp. 27-42
-
-
Foteinou, P.T.1
Calvano, S.E.2
Lowry, S.F.3
Androulakis, I.P.4
-
117
-
-
62849112761
-
In silico simulation of corticosteroids effect on an NFkB-dependent physicochemical model of systemic inflammation
-
Foteinou PT, Calvano SE, Lowry SF, Androulakis IP. In silico simulation of corticosteroids effect on an NFkB-dependent physicochemical model of systemic inflammation. PLoS ONE. 2009;4(3):e4706.
-
(2009)
PLoS ONE
, vol.4
, Issue.3
-
-
Foteinou, P.T.1
Calvano, S.E.2
Lowry, S.F.3
Androulakis, I.P.4
-
118
-
-
37549004342
-
A mathematical simulation of the inflammatory response to anthrax infection
-
Kumar R, Chow CC, Bartels J, Clermont G, Vodovotz Y. A mathematical simulation of the inflammatory response to anthrax infection. Shock 2008;29:104-11.
-
(2008)
Shock
, vol.29
, pp. 104-111
-
-
Kumar, R.1
Chow, C.C.2
Bartels, J.3
Clermont, G.4
Vodovotz, Y.5
-
119
-
-
77956321525
-
Using a mathematical model to analyze the role of probiotics and inflammation in necrotizing enterocolitis
-
Arciero J, Rubin J, Upperman J, Vodovotz Y, Ermentrout GB. Using a mathematical model to analyze the role of probiotics and inflammation in necrotizing enterocolitis. PLoS ONE. 2010;5:e10066
-
(2010)
PLoS ONE
, vol.5
-
-
Arciero, J.1
Rubin, J.2
Upperman, J.3
Vodovotz, Y.4
Ermentrout, G.B.5
-
120
-
-
67349228173
-
Toll-like receptor 2 ligands on the staphylococcal cell wall downregulate superantigen-induced T cell activation and prevent toxic shock syndrome
-
Chau TA, McCully ML, Brintnell W, An G, Kasper KJ, Vines ED, Kubes P, Haeryfar SM, McCormick JK, Cairns E, Heinrichs DE, Madrenas J. Toll-like receptor 2 ligands on the staphylococcal cell wall downregulate superantigen-induced T cell activation and prevent toxic shock syndrome. Nat Med. 2009;15(6):641-8.
-
(2009)
Nat Med
, vol.15
, Issue.6
, pp. 641-648
-
-
Chau, T.A.1
McCully, M.L.2
Brintnell, W.3
An, G.4
Kasper, K.J.5
Vines, E.D.6
Kubes, P.7
Haeryfar, S.M.8
McCormick, J.K.9
Cairns, E.10
Heinrichs, D.E.11
Madrenas, J.12
-
121
-
-
33749022785
-
In silico and in vivo approach to elucidate the inflammatory complexity of CD 14-deficient mice
-
Prince JM, Levy RM, Bartels J, Baratt A, Kane JM, III, Lagoa C, Rubin J, Day J, Wei J, Fink MP, Goyert SM, Clermont G, Billiar TR, Vodovotz Y. In silico and in vivo approach to elucidate the inflammatory complexity of CD 14-deficient mice. Mol Med. 2006;12:88-96.
-
(2006)
Mol Med
, vol.12
, pp. 88-96
-
-
Prince, J.M.1
Levy, R.M.2
Bartels, J.3
Baratt, A.4
Kane III., J.M.5
Lagoa, C.6
Rubin, J.7
Day, J.8
Wei, J.9
Fink, M.P.10
Goyert, S.M.11
Clermont, G.12
Billiar, T.R.13
Vodovotz, Y.14
-
122
-
-
33751222859
-
The role of initial trauma in the host's response to injury and hemorrhage: Insights from a comparison of mathematical simulations and hepatic transcriptomic analysis
-
Lagoa CE, Bartels J, Baratt A, Tseng G, Clermont G, Fink MP, Billiar TR, Vodovotz Y. The role of initial trauma in the host's response to injury and hemorrhage: Insights from a comparison of mathematical simulations and hepatic transcriptomic analysis. Shock. 2006;26:592-600.
-
(2006)
Shock
, vol.26
, pp. 592-600
-
-
Lagoa, C.E.1
Bartels, J.2
Baratt, A.3
Tseng, G.4
Clermont, G.5
Fink, M.P.6
Billiar, T.R.7
Vodovotz, Y.8
-
123
-
-
47849114337
-
An ensemble of models of the acute inflammatory response to bacterial lipopolysaccharide in rats: Results from parameter space reduction
-
Daun S, Rubin J, Vodovotz Y, Roy A, Parker R, Clermont G. An ensemble of models of the acute inflammatory response to bacterial lipopolysaccharide in rats: results from parameter space reduction. J Theor Biol. 2008;253:843-53.
-
(2008)
J Theor Biol
, vol.253
, pp. 843-853
-
-
Daun, S.1
Rubin, J.2
Vodovotz, Y.3
Roy, A.4
Parker, R.5
Clermont, G.6
-
124
-
-
77953214777
-
Multiscale model for the assessment of autonomic dysfunction in human endotoxemia
-
Foteinou PT, Calvano SE, Lowry SF, Androulakis IP. Multiscale model for the assessment of autonomic dysfunction in human endotoxemia. Physiol Genomics. 2010;42(1):5-19.
-
(2010)
Physiol Genomics
, vol.42
, Issue.1
, pp. 5-19
-
-
Foteinou, P.T.1
Calvano, S.E.2
Lowry, S.F.3
Androulakis, I.P.4
-
125
-
-
4043056616
-
In silico design of clinical trials: A method coming of age
-
Clermont G, Bartels J, Kumar R, Constantine G, Vodovotz Y, Chow C. In silico design of clinical trials: a method coming of age. Crit Care Med. 2004;32(10):2061-70.
-
(2004)
Crit Care Med
, vol.32
, Issue.10
, pp. 2061-2070
-
-
Clermont, G.1
Bartels, J.2
Kumar, R.3
Constantine, G.4
Vodovotz, Y.5
Chow, C.6
-
126
-
-
37349099044
-
Depressed heart rate variability is associated with high IL-6 blood level and decline in the blood pressure in septic patients
-
Tateishi Y, Oda S, Nakamura M, Watanabe K, Kuwaki T, Moriguchi T, Hirasawa H. Depressed heart rate variability is associated with high IL-6 blood level and decline in the blood pressure in septic patients. Shock. 2007;28(5):549-53.
-
(2007)
Shock
, vol.28
, Issue.5
, pp. 549-553
-
-
Tateishi, Y.1
Oda, S.2
Nakamura, M.3
Watanabe, K.4
Kuwaki, T.5
Moriguchi, T.6
Hirasawa, H.7
-
127
-
-
29344472545
-
-
editors, Providence, RI, American Mathematical Society
-
Fokas AS, Halliwell J, Kibble T, Zegarlinski B. editors. Highlights of Mathematical Physics. Providence, RI: American Mathematical Society; 2002.
-
(2002)
Highlights of Mathematical Physics
-
-
Fokas, A.S.1
Halliwell, J.2
Kibble, T.3
Zegarlinski, B.4
-
129
-
-
0000145419
-
The status role of modeling and simulation in materials science and engineering
-
Baskes MI. The status role of modeling and simulation in materials science and engineering. Curr Opin Solid State Mater Sci. 1999;4(3):273-7.
-
(1999)
Curr Opin Solid State Mater Sci
, vol.4
, Issue.3
, pp. 273-277
-
-
Baskes, M.I.1
-
130
-
-
0035132954
-
Present state and future directions of modeling of geochemistry in hydrogeological systems
-
van der Lee J, De Windt L. Present state and future directions of modeling of geochemistry in hydrogeological systems. J Contam Hydrol. 2001;47(2-4):265-82.
-
(2001)
J Contam Hydrol
, vol.47
, Issue.2-4
, pp. 265-282
-
-
van der Lee, J.1
De Windt, L.2
-
131
-
-
5644258227
-
In vivo, in vitro, in silico
-
Buchman TG. In vivo, in vitro, in silico. Crit.Care Med. 2004;32(10):2159-60.
-
(2004)
Crit.Care Med
, vol.32
, Issue.10
, pp. 2159-2160
-
-
Buchman, T.G.1
-
132
-
-
5644230749
-
Through a glass darkly: The brave new world of in silico modeling
-
Marshall JC. Through a glass darkly: the brave new world of in silico modeling. Crit Care Med. 2004;32(10):2157-9.
-
(2004)
Crit Care Med
, vol.32
, Issue.10
, pp. 2157-2159
-
-
Marshall, J.C.1
|