An Intrinsically Disordered Region of the Acetyltransferase p300 with Similarity to Prion-Like Domains Plays a Role in Aggregation

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Kirilyuk, Alexander ^a   Shimoji, Mika ^b   Catania, Jason ^a   Sahu, Geetaram ^a   Pattabiraman, Nagarajan ^c   Giordano, Antonio ^d   Albanese, Christopher ^a   Mocchetti, Italo ^b   Toretsky, Jeffrey A ^a   Uversky, Vladimir N ^e,f   Avantaggiati, Maria Laura ^a  

^a GEORGETOWN UNIVERSITY   (United States)

^b GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^c MolBox LLC   (United States)

^d Temple University   (United States)

^e UNIVERSITY OF SOUTH FLORIDA   (United States)

^f INSTITUTE FOR BIOLOGICAL INSTRUMENTATION   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; E1A ASSOCIATED P300 PROTEIN; PROTEIN P21; PROTEIN P53; TAU PROTEIN;

AGGRESOME; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL AGGREGATION; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; HUMAN; HUMAN CELL; HUMAN TISSUE; LEWY BODY; MOLECULAR INTERACTION; NONHUMAN; PARKINSON DISEASE; PROTEIN AGGREGATION; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; SEGREGATION ANALYSIS; TISSUE CULTURE CELL; UBIQUITINATION;

ALPHA-SYNUCLEIN; ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; AUTOPHAGY; CERCOPITHECUS AETHIOPS; COS CELLS; DOWN-REGULATION; HUMANS; LEWY BODIES; MOLECULAR SEQUENCE DATA; NEOPLASMS; NEURODEGENERATIVE DISEASES; OXIDATIVE STRESS; P300-CBP TRANSCRIPTION FACTORS; PARKINSON DISEASE; PRIONS; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84868317144     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0048243     Document Type: Article

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