Cystic fibrosis and CFTR

Pflugers Archiv European Journal of Physiology

Volumn 443, Issue SUPPL. 1, 2001, Pages

  Greger, R ^a   Schreiber, R ^a   Mall, M ^a   Wissner, A ^a   Hopf, A ^a   Briel, M ^a   Bleich, M ^a   Warth, R ^a   Kunzelmann, K ^a,b  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Airways; CFTR; Cystic fibrosis; Cystic fibrosis transmembrane conductance regulator; ENaC; Epithelial Na+ channel; Epithelium; Intestine

Indexed keywords

CHLORIDE CHANNEL; TRANSMEMBRANE CONDUCTANCE REGULATOR;

CONFERENCE PAPER; CYSTIC FIBROSIS; GENE FUNCTION; GENE MUTATION; GENE THERAPY; HUMAN; ION TRANSPORT; MOLECULAR INTERACTION; PRIORITY JOURNAL;

CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; EPITHELIAL SODIUM CHANNEL; HUMANS; SODIUM CHANNELS;

EID: 0035192131     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004240100635     Document Type: Conference Paper

References (55)

1. Demonstration that CFTR is a chloride channel by alteration of its anion selectivity
2. Purification and functional reconstitution of the cystic fibrosis transmembrane conductance regulator (CFTR)
3. + channel blocker 293B
4. + transport in cystic fibrosis respiratory epithelia
5. + channels (ENaCs) in Xenopus oocytes co-expressing CFTR and ENaC
6. CFTR: Mechanism of anion conduction
7. Abnormal electrolyte composition of sweat in cystic fibrosis of the pancreas
8. + conductance of rat colonic crypt cells is suppressed by forskolin
9. Control of CFTR channel gating by phosphorylation and nucleotide hydrolysis
10. Role of CFTR in the colon
11. Cystic fibrosis
12. 29 cells
13. Regulation of ion transport in colonic crypts
14. Does stimulation of NaC1 secretion in in vitro perfused rectal gland tubules of Squalus acanthias increase membrane capacitance?
15. + absorption in cystic fibrosis mice versus normal mice
16. Pathophysiology of gene-targeted mouse models for cystic fibrosis
17. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
18. A multifunctional aqueous channel formed by CFTR
19. Mutations in the putative pore-forming domain of CFTR do not change anion selectivity of the cAMP activated C1- conductance
20. cAMP-regulated trafficking of epitope-tagged CFTR
21. The role of exocytosis in the activation of the chloride conductance in Chinese hamster ovary cells (CHO) stably expressing CFTR
22. cAMP-independent activation of CFTR C1- channels by the tyrosine kinase inhibitor genistein
23. Multiple proteolytic systems, including the proteasome, contribute to CFTR processing
24. 0 guanine nucleotide-binding regulatory protein
25. Biosynthesis and degradation of CFTR
26. cAMP-dependent activation of small-conductance C1- channels in HT29 colon carcinoma cells
27. + currents by intracellular domains of the cystic fibrosis transmembrane regulator
28. 2+ activated C1- conductance of Xenopus oocytes
29. No evidence for direct activation of the cystic fibrosis transmembrane regulator by 8-cyclopentyl-1,3-dipropylxanthine
30. + conductance is reduced by the cystic fibrosis transmembrane conductance regulator in normal but not in cystic fibrosis airways
31. + conductance
32. Cholinergic ion secretion in human colon requires coactivation by cAMP
33. + conductance when coexpressed in Xenopus oocytes
34. + channel activity involves phosphorylation processes
35. Vesicle targeting and ion secretion in epithelial cells: Implications for cystic fibrosis
36. Acute safety and effects on mucociliary clearance of aerosolized uridine 5-triphosphate +/- amiloride in normal human adults
37. Evidence for safety and efficacy of DOTAP cationic liposomemediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis
38. Chloride impermeability in cystic fibrosis
39. Physiological basis of cystic fibrosis: A historical perspective
40. Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA
41. In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium
42. Cystic fibrosis transmembrane conductance regulator activates water conductance in Xenopus oocytes
43. + channel
44. The cystic fibrosis transmembrane conductance regulator activates aquaporin 3 in airway epithelial cells
45. Pharmacology of CFTR chloride channel activity
46. Micropuncture studies of the sweat formation in cystic fibrosis patients
47. CFTR regulates outwardly rectifying chloride channels through an autocrine mechanism involving ATP
48. CFTR is a conductance regulator as well as a chloride channel
49. Structure and function of the CFTR chloride channel
50. Regulation of C1- channels in normal and cystic fibrosis airway epithelial cells by extracellular ATP
51. CFTR as a cAMP-dependent regulator of sodium channels
52. Phosphorylation-regulated C1- channel in CHO cells stably expressing the cystic fibrosis gene
53. CFTR modulates the ATP response of Chinese hamster ovary cells (CHO)
54. Determinants of mild clinical symptoms in cystic fibrosis patients. Residual chloride secretion measured in rectal biopsies in relation to the genotype
55. + channel (rSK4) of colonic crypts