The ribonucleotide reductase inhibitor, Sml1, is sequentially phosphorylated, ubiquitylated and degraded in response to DNA damage

Nucleic Acids Research

Volumn 38, Issue 19, 2010, Pages 6490-6501

  Andreson, Bethany L ^a   Gupta, Amitabha ^a   Georgieva, Bilyana P ^b,c   Rothstein, Rodney ^b  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b Columbia University Medical School ^*  (United States)

^c WILMER CUTLER PICKERING HALE AND DORR LLP   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; DNA; OXIDOREDUCTASE INHIBITOR; PROTEASOME; PROTEASOME 26S; PROTEIN MUB1; PROTEIN RAD6; PROTEIN SML1; PROTEIN UBR2; RIBONUCLEOTIDE REDUCTASE; UBIQUITIN CONJUGATING ENZYME; UBIQUITIN CONJUGATING ENZYME E2; UBIQUITIN CONJUGATING ENZYME E3; UNCLASSIFIED DRUG;

ARTICLE; CELL SURVIVAL; COMPLEX FORMATION; CONTROLLED STUDY; DNA DAMAGE; ENZYME REGULATION; GENE MUTATION; GENOMIC INSTABILITY; GENOTOXICITY; LETHALITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; SACCHAROMYCES CEREVISIAE; UBIQUITINATION;

AMINO ACID SUBSTITUTION; CARRIER PROTEINS; DEOXYRIBONUCLEOTIDES; DNA DAMAGE; DOWN-REGULATION; MUTATION; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; SACCHAROMYCES CEREVISIAE PROTEINS; UBIQUITIN-CONJUGATING ENZYMES; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 78049369559     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkq552     Document Type: Article

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