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Volumn 14, Issue SUPPL.4, 2012, Pages

Molecular markers in pediatric neuro-oncology

Author keywords

astrocytomas; intracranial germ cell tumors; medulloblastomas

Indexed keywords

B RAF KINASE; HISTONE H3; IMATINIB; ISOCITRATE DEHYDROGENASE 1; ISOCITRATE DEHYDROGENASE 2; KIAA1549 PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MOLECULAR MARKER; NEUROFIBROMIN; PROTEIN; SMARCB1 PROTEIN; TUMOR MARKER; UNCLASSIFIED DRUG; WNT PROTEIN;

EID: 84868014646     PISSN: 15228517     EISSN: 15235866     Source Type: Journal    
DOI: 10.1093/neuonc/nos204     Document Type: Article
Times cited : (33)

References (80)
  • 3
    • 14244265590 scopus 로고    scopus 로고
    • Epidemiology and etiology of gliomas
    • DOI 10.1007/s00401-005-0991-y
    • Ohgaki H, Kleihues P. Epidemiology and etiology of gliomas. Acta Neuropathol. 2005;109:93-108. (Pubitemid 40287792)
    • (2005) Acta Neuropathologica , vol.109 , Issue.1 , pp. 93-108
    • Ohgaki, H.1    Kleihues, P.2
  • 4
    • 55349107544 scopus 로고    scopus 로고
    • Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas
    • Jones DT, Kocialkowski S, Liu L, et al. Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas. Cancer Res. 2008;68:8673-8677.
    • (2008) Cancer Res. , vol.68 , pp. 8673-8677
    • Jones, D.T.1    Kocialkowski, S.2    Liu, L.3
  • 5
    • 66849099801 scopus 로고    scopus 로고
    • Activation of the ERK/MAPK pathway: A signature genetic defect in posterior fossa pilocytic astrocytomas
    • Forshew T, Tatevossian RG, Lawson AR, et al. Activation of the ERK/MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas. J Pathol. 2009;218:172-181.
    • (2009) J Pathol. , vol.218 , pp. 172-181
    • Forshew, T.1    Tatevossian, R.G.2    Lawson, A.R.3
  • 6
    • 68349088073 scopus 로고    scopus 로고
    • Combined molecular analysis of BRAF and IDH1 distinguishes pilocytic astrocytoma from diffuse astro-cytoma
    • Korshunov A, Meyer J, Capper D, et al. Combined molecular analysis of BRAF and IDH1 distinguishes pilocytic astrocytoma from diffuse astro-cytoma. Acta Neuropathol. 2009;118:401-405.
    • (2009) Acta Neuropathol. , vol.118 , pp. 401-405
    • Korshunov, A.1    Meyer, J.2    Capper, D.3
  • 8
    • 79958087774 scopus 로고    scopus 로고
    • Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma
    • Cin H, Meyer C, Herr R, et al. Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma. Acta Neuropathol. 2011;121:763-774.
    • (2011) Acta Neuropathol. , vol.121 , pp. 763-774
    • Cin, H.1    Meyer, C.2    Herr, R.3
  • 9
    • 80052273582 scopus 로고    scopus 로고
    • Functional characterization of a BRAF insertion mutant associated with pilocytic astrocytoma
    • Eisenhardt AE, Olbrich H, Roring M, et al. Functional characterization of a BRAF insertion mutant associated with pilocytic astrocytoma. Int J Cancer. 2011;129:2297-2303.
    • (2011) Int J Cancer. , vol.129 , pp. 2297-2303
    • Eisenhardt, A.E.1    Olbrich, H.2    Roring, M.3
  • 10
    • 67349219657 scopus 로고    scopus 로고
    • Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma
    • Jones DT, Kocialkowski S, Liu L, Pearson DM, Ichimura K, Collins VP. Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma. Oncogene. 2009;28:2119-2123.
    • (2009) Oncogene. , vol.28 , pp. 2119-2123
    • Jones, D.T.1    Kocialkowski, S.2    Liu, L.3    Pearson, D.M.4    Ichimura, K.5    Collins, V.P.6
  • 11
    • 79954441895 scopus 로고    scopus 로고
    • Analysis of BRAF V600E mutation in 1, 320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma
    • Schindler G, Capper D, Meyer J, et al. Analysis of BRAF V600E mutation in 1, 320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma. Acta Neuropathol. 2011;121:397-405.
    • (2011) Acta Neuropathol. , vol.121 , pp. 397-405
    • Schindler, G.1    Capper, D.2    Meyer, J.3
  • 12
    • 68749098096 scopus 로고    scopus 로고
    • Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours
    • Jacob K, Albrecht S, Sollier C, et al. Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours. Br J Cancer. 2009;101:722-733.
    • (2009) Br J Cancer. , vol.101 , pp. 722-733
    • Jacob, K.1    Albrecht, S.2    Sollier, C.3
  • 13
    • 80055084211 scopus 로고    scopus 로고
    • BRAF-KIAA1549 fusion transcripts are less frequent in pilocytic astrocytomas diagnosed in adults
    • Hasselblatt M, Riesmeier B, Lechtape B, et al. BRAF-KIAA1549 fusion transcripts are less frequent in pilocytic astrocytomas diagnosed in adults. Neuropathol Appl Neurobiol. 2011;37:803-806.
    • (2011) Neuropathol Appl Neurobiol. , vol.37 , pp. 803-806
    • Hasselblatt, M.1    Riesmeier, B.2    Lechtape, B.3
  • 15
    • 79958136272 scopus 로고    scopus 로고
    • Adult grade II diffuse astrocytomas are genetically distinct from and more aggressive than their paediatric counterparts
    • Jones DT, Mulholland SA, Pearson DM, et al. Adult grade II diffuse astrocytomas are genetically distinct from and more aggressive than their paediatric counterparts. Acta Neuropathol. 2011;121:753-761.
    • (2011) Acta Neuropathol. , vol.121 , pp. 753-761
    • Jones, D.T.1    Mulholland, S.A.2    Pearson, D.M.3
  • 16
    • 76549137130 scopus 로고    scopus 로고
    • Oncogenic BRAF mutation with CDKN2A inactivation is characteristic of a subset of pediatric malignant astrocytomas
    • Schiffman JD, Hodgson JG, VandenBerg SR, et al. Oncogenic BRAF mutation with CDKN2A inactivation is characteristic of a subset of pediatric malignant astrocytomas. Cancer Res. 2010;70:512-519.
    • (2010) Cancer Res. , vol.70 , pp. 512-519
    • Schiffman, J.D.1    Hodgson, J.G.2    Vandenberg, S.R.3
  • 17
    • 78149467927 scopus 로고    scopus 로고
    • Activating mutations in BRAF characterize a spectrum of pediatric low-grade gliomas
    • Dougherty MJ, Santi M, Brose MS, et al. Activating mutations in BRAF characterize a spectrum of pediatric low-grade gliomas. Neuro Oncol. 2010;12:621-630.
    • (2010) Neuro Oncol. , vol.12 , pp. 621-630
    • Dougherty, M.J.1    Santi, M.2    Brose, M.S.3
  • 18
    • 79953184268 scopus 로고    scopus 로고
    • BRAF V600E mutations are common in pleomorphic xanthoastrocytoma: Diagnostic and therapeutic implications
    • Dias-Santagata D, Lam Q, Vernovsky K, et al. BRAF V600E mutations are common in pleomorphic xanthoastrocytoma: diagnostic and therapeutic implications. PloS one. 2011;6:e17948.
    • (2011) PloS One. , vol.6
    • Dias-Santagata, D.1    Lam, Q.2    Vernovsky, K.3
  • 20
    • 60849115270 scopus 로고    scopus 로고
    • IDH1 and IDH2 mutations in gliomas
    • Yan H, Parsons DW, Jin G, et al. IDH1 and IDH2 mutations in gliomas. N Engl J Med. 2009;360:765-773.
    • (2009) N Engl J Med. , vol.360 , pp. 765-773
    • Yan, H.1    Parsons, D.W.2    Jin, G.3
  • 21
    • 33847053161 scopus 로고    scopus 로고
    • Frequent loss of chromosome 9, homozygous CDKN2A/p14(ARF)/CDKN2B deletion and low TSC1 mRNA expression in pleomorphic xanthoastrocytomas
    • Weber RG, Hoischen A, Ehrler M, et al. Frequent loss of chromosome 9, homozygous CDKN2A/p14(ARF)/CDKN2B deletion and low TSC1 mRNA expression in pleomorphic xanthoastrocytomas. Oncogene. 2007;26:1088-1097.
    • (2007) Oncogene. , vol.26 , pp. 1088-1097
    • Weber, R.G.1    Hoischen, A.2    Ehrler, M.3
  • 22
    • 84861918640 scopus 로고    scopus 로고
    • Cooperative interactions of BRAFV600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy
    • Huillard E, Hashizume R, Phillips JJ, et al. Cooperative interactions of BRAFV600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy. Proc Natl Acad Sci U S A. 2012;109:8710-8715.
    • (2012) Proc Natl Acad Sci U S A. , vol.109 , pp. 8710-8715
    • Huillard, E.1    Hashizume, R.2    Phillips, J.J.3
  • 24
    • 84862777348 scopus 로고    scopus 로고
    • Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblas-toma
    • Schwartzentruber J, Korshunov A, Liu XY, et al. Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblas-toma. Nature. 2012;482:226-231.
    • (2012) Nature. , vol.482 , pp. 226-231
    • Schwartzentruber, J.1    Korshunov, A.2    Liu, X.Y.3
  • 25
    • 84862777410 scopus 로고    scopus 로고
    • Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblas-tomas
    • Wu G, Broniscer A, McEachron TA, et al. Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblas-tomas. Nature Genet. 2012;44:251-253.
    • (2012) Nature Genet. , vol.44 , pp. 251-253
    • Wu, G.1    Broniscer, A.2    McEachron, T.A.3
  • 26
    • 79952279828 scopus 로고    scopus 로고
    • DAXXATRX MEN1 and MTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors
    • Jiao Y, Shi C, Edil BH, et al. DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors. Science. 2011;331:1199-1203.
    • (2011) Science. , vol.331 , pp. 1199-1203
    • Jiao, Y.1    Shi, C.2    Edil, B.H.3
  • 27
    • 79960700556 scopus 로고    scopus 로고
    • Altered telomeres in tumors with ATRX and DAXX mutations
    • Heaphy CM, de Wilde RF, Jiao Y, et al. Altered telomeres in tumors with ATRX and DAXX mutations. Science. 2011;333:425.
    • (2011) Science , vol.333 , pp. 425
    • Heaphy, C.M.1    De Wilde, R.F.2    Jiao, Y.3
  • 28
    • 84867606428 scopus 로고    scopus 로고
    • Hotspot Mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma
    • In press
    • Sturm D, Witt H, Hovestadt V, et al. Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma. Cancer Cell. 2012; In press.
    • (2012) Cancer Cell.
    • Sturm, D.1    Witt, H.2    Hovestadt, V.3
  • 29
    • 84865863019 scopus 로고    scopus 로고
    • K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas
    • Khuong-Quang DA, Buczkowicz P, Rakopoulos P, et al. K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas. Acta Neuropathol. 2012;124:439-447.
    • (2012) Acta Neuropathol. , vol.124 , pp. 439-447
    • Khuong-Quang, D.A.1    Buczkowicz, P.2    Rakopoulos, P.3
  • 30
    • 79951825581 scopus 로고    scopus 로고
    • Homozygous loss of ADAM3A revealed by genome-wide analysis of pediatric high-grade glioma and diffuse intrinsic pontine gliomas
    • Barrow J, Adamowicz-Brice M, Cartmill M, et al. Homozygous loss of ADAM3A revealed by genome-wide analysis of pediatric high-grade glioma and diffuse intrinsic pontine gliomas. Neuro Oncol. 2011; 13:212-222.
    • (2011) Neuro Oncol. , vol.13 , pp. 212-222
    • Barrow, J.1    Adamowicz-Brice, M.2    Cartmill, M.3
  • 31
    • 80054771090 scopus 로고    scopus 로고
    • Genome-wide analyses identify recurrent amplifications of receptor tyrosine kinases and cell-cycle regulatory genes in diffuse intrinsic pontine glioma
    • Paugh BS, Broniscer A, Qu C, et al. Genome-wide analyses identify recurrent amplifications of receptor tyrosine kinases and cell-cycle regulatory genes in diffuse intrinsic pontine glioma. J Clin Oncol. 2011;29:3999-4006.
    • (2011) J Clin Oncol. , vol.29 , pp. 3999-4006
    • Paugh, B.S.1    Broniscer, A.2    Qu, C.3
  • 32
    • 84857527038 scopus 로고    scopus 로고
    • Mesenchymal transition and PDGFRA amplification/mutation are key distinct oncogenic events in pediatric diffuse intrinsic pontine gliomas
    • Puget S, Philippe C, Bax DA, et al. Mesenchymal transition and PDGFRA amplification/mutation are key distinct oncogenic events in pediatric diffuse intrinsic pontine gliomas. PloS one. 2012;7:e30313.
    • (2012) PloS One. , vol.7
    • Puget, S.1    Philippe, C.2    Bax, D.A.3
  • 33
    • 77954596239 scopus 로고    scopus 로고
    • Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease
    • Paugh BS, Qu C, Jones C, et al. Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease. J Clin Oncol. 2010;28:3061-3068.
    • (2010) J Clin Oncol. , vol.28 , pp. 3061-3068
    • Paugh, B.S.1    Qu, C.2    Jones, C.3
  • 34
    • 77955477993 scopus 로고    scopus 로고
    • Molecular staging of intracranial ependymoma in children and adults
    • Korshunov A, Witt H, Hielscher T, et al. Molecular staging of intracranial ependymoma in children and adults. JClin Oncol. 2010;28:3182-3190.
    • (2010) JClin Oncol. , vol.28 , pp. 3182-3190
    • Korshunov, A.1    Witt, H.2    Hielscher, T.3
  • 35
    • 80051580421 scopus 로고    scopus 로고
    • Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma
    • Witt H, Mack SC, Ryzhova M, et al. Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma. Cancer Cell. 2011;20:143-157.
    • (2011) Cancer Cell. , vol.20 , pp. 143-157
    • Witt, H.1    MacK, S.C.2    Ryzhova, M.3
  • 36
    • 84860821444 scopus 로고    scopus 로고
    • Molecular subgroups of medulloblastoma: The current consensus
    • Taylor MD, Northcott PA, Korshunov A, et al. Molecular subgroups of medulloblastoma: the current consensus. Acta Neuropathol. 2012;123:465-472.
    • (2012) Acta Neuropathol. , vol.123 , pp. 465-472
    • Taylor, M.D.1    Northcott, P.A.2    Korshunov, A.3
  • 38
    • 84863393028 scopus 로고    scopus 로고
    • Molecular subgroups of medulloblastoma: An international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas
    • Kool M, Korshunov A, Remke M, et al. Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas. Acta Neuropathol. 2012;123:473-484.
    • (2012) Acta Neuropathol. , vol.123 , pp. 473-484
    • Kool, M.1    Korshunov, A.2    Remke, M.3
  • 39
    • 78650811198 scopus 로고    scopus 로고
    • Subtypes of medulloblastoma have distinct developmental origins
    • Gibson P, Tong Y, Robinson G, et al. Subtypes of medulloblastoma have distinct developmental origins. Nature. 2010;468:1095-1099.
    • (2010) Nature. , vol.468 , pp. 1095-1099
    • Gibson, P.1    Tong, Y.2    Robinson, G.3
  • 40
    • 52449119078 scopus 로고    scopus 로고
    • Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features
    • Kool M, Koster J, Bunt J, et al. Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features. PloS one. 2008;3:e3088.
    • (2008) PloS One. , vol.3
    • Kool, M.1    Koster, J.2    Bunt, J.3
  • 42
    • 0036648241 scopus 로고    scopus 로고
    • Mutations in SUFU predispose to medulloblastoma
    • Taylor MD, Liu L, Raffel C, et al. Mutations in SUFU predispose to medulloblastoma. Nature Genet. 2002;31:306-310.
    • (2002) Nature Genet. , vol.31 , pp. 306-310
    • Taylor, M.D.1    Liu, L.2    Raffel, C.3
  • 43
    • 63449115501 scopus 로고    scopus 로고
    • Multiple recurrent genetic events converge on control of histone lysine methylation in medullo-blastoma
    • Northcott PA, Nakahara Y, Wu X, et al. Multiple recurrent genetic events converge on control of histone lysine methylation in medullo-blastoma. Nature Genet. 2009;41:465-472.
    • (2009) Nature Genet. , vol.41 , pp. 465-472
    • Northcott, P.A.1    Nakahara, Y.2    Wu, X.3
  • 44
    • 79955034739 scopus 로고    scopus 로고
    • Medulloblastoma comprises four distinct molecular variants
    • Northcott PA, Korshunov A, Witt H, et al. Medulloblastoma comprises four distinct molecular variants. J Clin Oncol. 2011;29:1408-1414.
    • (2011) J Clin Oncol. , vol.29 , pp. 1408-1414
    • Northcott, P.A.1    Korshunov, A.2    Witt, H.3
  • 45
    • 84862907577 scopus 로고    scopus 로고
    • Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations
    • Rausch T, Jones DT, Zapatka M, et al. Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations. Cell. 2012;148:59-71.
    • (2012) Cell. , vol.148 , pp. 59-71
    • Rausch, T.1    Jones, D.T.2    Zapatka, M.3
  • 46
    • 84864425646 scopus 로고    scopus 로고
    • Subgroup specific structural variation across 1, 000 medulloblastoma genomes
    • Northcott PA, Shih DJH, Peacock J, et al. Subgroup specific structural variation across 1, 000 medulloblastoma genomes. Nature. 2012; 488:49-56
    • (2012) Nature. , vol.488 , pp. 49-56
    • Northcott, P.A.1    Shih, D.J.H.2    Peacock, J.3
  • 47
    • 79951934386 scopus 로고    scopus 로고
    • TP53 mutation is frequently associated with CTNNB1 mutation or MYCN amplification and is compatible with long-term survival in medulloblastoma
    • Pfaff E, Remke M, Sturm D, et al. TP53 mutation is frequently associated with CTNNB1 mutation or MYCN amplification and is compatible with long-term survival in medulloblastoma. J Clin Oncol. 2010;28:5188-5196.
    • (2010) J Clin Oncol. , vol.28 , pp. 5188-5196
    • Pfaff, E.1    Remke, M.2    Sturm, D.3
  • 48
    • 84862685324 scopus 로고    scopus 로고
    • MYC family amplification and clinical risk-factors interact to predict an extremely poor prognosis in childhood medulloblastoma
    • Ryan SL, Schwalbe EC, Cole M, et al. MYC family amplification and clinical risk-factors interact to predict an extremely poor prognosis in childhood medulloblastoma. Acta Neuropathol. 2012;123:501-513.
    • (2012) Acta Neuropathol. , vol.123 , pp. 501-513
    • Ryan, S.L.1    Schwalbe, E.C.2    Cole, M.3
  • 49
    • 59949097396 scopus 로고    scopus 로고
    • Novel mechanisms of gene disruption at the medulloblastoma isodicentric 17p11 breakpoint
    • McCabe MG, Ichimura K, Pearson DM, et al. Novel mechanisms of gene disruption at the medulloblastoma isodicentric 17p11 breakpoint. Genes Chromosomes Cancer. 2009;48:121-131.
    • (2009) Genes Chromosomes Cancer. , vol.48 , pp. 121-131
    • McCabe, M.G.1    Ichimura, K.2    Pearson, D.M.3
  • 50
    • 84864419974 scopus 로고    scopus 로고
    • ICGC PedBrain: Dissecting the genomic complexity underlying medulloblastoma
    • Jones DTW, Jäger N, Kool M, et al. ICGC PedBrain: Dissecting the genomic complexity underlying medulloblastoma. Nature. 2012;488:100-105.
    • (2012) Nature. , vol.488 , pp. 100-105
    • Jones, D.T.W.1    Jäger, N.2    Kool, M.3
  • 51
    • 79251629946 scopus 로고    scopus 로고
    • The genetic landscape of the childhood cancer medulloblastoma
    • Parsons DW, Li M, Zhang X, et al. The genetic landscape of the childhood cancer medulloblastoma. Science. 2011;331:435-439.
    • (2011) Science. , vol.331 , pp. 435-439
    • Parsons, D.W.1    Li, M.2    Zhang, X.3
  • 52
    • 84864492215 scopus 로고    scopus 로고
    • Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations
    • Pugh TJ, Weeraratne SD, Archer TC, et al. Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations. Nature. 2012;488:106-110.
    • (2012) Nature. , vol.488 , pp. 106-110
    • Pugh, T.J.1    Weeraratne, S.D.2    Archer, T.C.3
  • 53
    • 84864444165 scopus 로고    scopus 로고
    • Novel mutations target distinct subgroups of medulloblastoma
    • Epub ahead of print
    • Robinson G, Parker M, Kranenburg TA, et al. Novel mutations target distinct subgroups of medulloblastoma. Nature. 2012; [Epub ahead of print].
    • (2012) Nature.
    • Robinson, G.1    Parker, M.2    Kranenburg, T.A.3
  • 54
    • 77954602395 scopus 로고    scopus 로고
    • Adult and pediatric medullo-blastomas are genetically distinct and require different algorithms for molecular risk stratification
    • Korshunov A, Remke M, Werft W, et al. Adult and pediatric medullo-blastomas are genetically distinct and require different algorithms for molecular risk stratification. J Clin Oncol. 2010;28:3054-3060.
    • (2010) J Clin Oncol. , vol.28 , pp. 3054-3060
    • Korshunov, A.1    Remke, M.2    Werft, W.3
  • 56
    • 79960842253 scopus 로고    scopus 로고
    • Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct
    • Northcott PA, Hielscher T, Dubuc A, et al. Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct. Acta Neuropathol. 2011;122:231-240.
    • (2011) Acta Neuropathol. , vol.122 , pp. 231-240
    • Northcott, P.A.1    Hielscher, T.2    Dubuc, A.3
  • 58
    • 66749119101 scopus 로고    scopus 로고
    • Frequent IDH1 mutations in supratentorial primitive neuroectoder-mal tumors (sPNET) of adults but not children
    • Hayden JT, Fruhwald MC, Hasselblatt M, Ellison DW, Bailey S, Clifford SC. Frequent IDH1 mutations in supratentorial primitive neuroectoder-mal tumors (sPNET) of adults but not children. Cell Cycle. 2009;8:1806-1807.
    • (2009) Cell Cycle. , vol.8 , pp. 1806-1807
    • Hayden, J.T.1    Fruhwald, M.C.2    Hasselblatt, M.3    Ellison, D.W.4    Bailey, S.5    Clifford, S.C.6
  • 61
    • 80052737349 scopus 로고    scopus 로고
    • Genome-wide molecular characterization of central nervous system primitive neuroectodermal tumor and pineoblastoma
    • Miller S, Rogers HA, Lyon P, et al. Genome-wide molecular characterization of central nervous system primitive neuroectodermal tumor and pineoblastoma. Neuro Oncol. 2011;13:866-879.
    • (2011) Neuro Oncol. , vol.13 , pp. 866-879
    • Miller, S.1    Rogers, H.A.2    Lyon, P.3
  • 62
    • 84864354788 scopus 로고    scopus 로고
    • Markers of survival and metastatic potential in childhood CNS primitive neuro-ectodermal brain tumours: An integrative genomic analysis
    • Picard D, Miller S, Hawkins CE, et al. Markers of survival and metastatic potential in childhood CNS primitive neuro-ectodermal brain tumours: an integrative genomic analysis. Lancet Oncol. 2012; 13;838-848.
    • (2012) Lancet Oncol. , vol.13 , pp. 838-848
    • Picard, D.1    Miller, S.2    Hawkins, C.E.3
  • 63
    • 65649112882 scopus 로고    scopus 로고
    • Novel genomic amplification targeting the microRNA cluster at 19q13.42 in a pediatric embryonal tumor with abundant neuropil and true rosettes
    • Pfister S, Remke M, Castoldi M, et al. Novel genomic amplification targeting the microRNA cluster at 19q13.42 in a pediatric embryonal tumor with abundant neuropil and true rosettes. Acta Neuropathol. 2009;117:457-464.
    • (2009) Acta Neuropathol. , vol.117 , pp. 457-464
    • Pfister, S.1    Remke, M.2    Castoldi, M.3
  • 64
    • 77957284808 scopus 로고    scopus 로고
    • Focal genomic amplification at 19q13.42 comprises a powerful diagnostic marker for embryonal tumors with ependymoblastic rosettes
    • Korshunov A, Remke M, Gessi M, et al. Focal genomic amplification at 19q13.42 comprises a powerful diagnostic marker for embryonal tumors with ependymoblastic rosettes. Acta Neuropathol. 2010;120:253-260.
    • (2010) Acta Neuropathol. , vol.120 , pp. 253-260
    • Korshunov, A.1    Remke, M.2    Gessi, M.3
  • 65
    • 84865510309 scopus 로고    scopus 로고
    • Analysis of Chromosome 19q13.42 Amplification in Embryonal Brain Tumors with Ependymoblastic Multilayered Rosettes. [published online ahead of print February 10, 2012]
    • doi:10.1111/j.1750-3639.2012.00574.x
    • Nobusawa S, Yokoo H, Hirato J, et al. Analysis of Chromosome 19q13.42 Amplification in Embryonal Brain Tumors with Ependymoblastic Multilayered Rosettes. [published online ahead of print February 10, 2012]. J Clin Oncol. 2012. doi:10.1111/j.1750-3639.2012.00574.x
    • (2012) J Clin Oncol.
    • Nobusawa, S.1    Yokoo, H.2    Hirato, J.3
  • 71
    • 79957975801 scopus 로고    scopus 로고
    • Nonsense mutation and inactiva-tion of SMARCA4 (BRG1) in an atypical teratoid/rhabdoid tumor showing retained SMARCB1 (INI1) expression
    • Hasselblatt M, Gesk S, Oyen F, et al. Nonsense mutation and inactiva-tion of SMARCA4 (BRG1) in an atypical teratoid/rhabdoid tumor showing retained SMARCB1 (INI1) expression. Am J Surg Pathol. 2011;35:933-935.
    • (2011) Am J Surg Pathol. , vol.35 , pp. 933-935
    • Hasselblatt, M.1    Gesk, S.2    Oyen, F.3
  • 72
    • 84876323128 scopus 로고    scopus 로고
    • Report of Brain Tumor Registry of Japan (1984-2000)
    • Report of Brain Tumor Registry of Japan (1984-2000). Neurol Med Chir (Tokyo). 2009;49(Suppl):1-101.
    • (2009) Neurol Med Chir (Tokyo). , vol.49 , Issue.SUPPL. , pp. 1-101
  • 73
    • 78650003580 scopus 로고    scopus 로고
    • The GIST paradigm: Lessons for other kinase-driven cancers
    • Antonescu CR. The GIST paradigm: lessons for other kinase-driven cancers. J Pathol. 2011;223:251-261.
    • (2011) J Pathol. , vol.223 , pp. 251-261
    • Antonescu, C.R.1
  • 74
    • 5044234118 scopus 로고    scopus 로고
    • C-kit gene mutations in intracranial germinomas
    • DOI 10.1111/j.1349-7006.2004.tb03251.x
    • Sakuma Y, Sakurai S, Oguni S, Satoh M, Hironaka M, Saito K. c-kit gene mutations in intracranial germinomas. Cancer Sci. 2004;95:716-720. (Pubitemid 39335090)
    • (2004) Cancer Science , vol.95 , Issue.9 , pp. 716-720
    • Sakuma, Y.1    Sakurai, S.2    Oguni, S.3    Satoh, M.4    Hironaka, M.5    Saito, K.6
  • 75
    • 33645740589 scopus 로고    scopus 로고
    • C-kit gene mutation: Common and widely distributed in intracranial germinomas
    • PEDIATRICS
    • Kamakura Y, Hasegawa M, Minamoto T, Yamashita J, Fujisawa H. C-kit gene mutation: common and widely distributed in intracranial germinomas. J Neurosurg. 2006;104:173-180. (Pubitemid 44954841)
    • (2006) Journal of Neurosurgery , vol.104 , Issue.SUPPL. 3 , pp. 173-180
    • Kamakura, Y.1    Hasegawa, M.2    Minamoto, T.3    Yamashita, J.4    Fujisawa, H.5
  • 76
    • 56749156604 scopus 로고    scopus 로고
    • Correlation of kinase genotype and clinical outcome in the North American Intergroup Phase III Trial of imatinib mesylate for treatment of advanced gastrointestinal stromal tumor: CALGB 150105 Study by Cancer and Leukemia Group B and Southwest Oncology Group
    • Heinrich MC, Owzar K, Corless CL, et al. Correlation of kinase genotype and clinical outcome in the North American Intergroup Phase III Trial of imatinib mesylate for treatment of advanced gastrointestinal stromal tumor: CALGB 150105 Study by Cancer and Leukemia Group B and Southwest Oncology Group. J Clin Oncol. 2008;26:5360-5367.
    • (2008) J Clin Oncol. , vol.26 , pp. 5360-5367
    • Heinrich, M.C.1    Owzar, K.2    Corless, C.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.