메뉴 건너뛰기




Volumn 17, Issue 11, 2012, Pages 1093-1102

Statistical epistasis and progressive brain change in schizophrenia: An approach for examining the relationships between multiple genes

Author keywords

epistasis; genomics; longitudinal studies; progressive brain change; schizophrenia; structural MR imaging

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CATECHOL METHYLTRANSFERASE; DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN; DYSBINDIN; EPIDERMAL GROWTH FACTOR RECEPTOR 4; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; NEU DIFFERENTIATION FACTOR; PHOSPHODIESTERASE IV; REELIN; RGS4 PROTEIN;

EID: 84867899777     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/mp.2011.108     Document Type: Article
Times cited : (22)

References (69)
  • 1
    • 25144501575 scopus 로고    scopus 로고
    • Genetic association studies
    • DOI 10.1016/S0140-6736(05)67424-7, PII S0140673605674247
    • Cordell HJ, Clayton DG. Genetic association studies. Lancet 2005; 366: 1121-1131. (Pubitemid 41338767)
    • (2005) Lancet , vol.366 , Issue.9491 , pp. 1121-1131
    • Cordell, H.J.1    Clayton, D.G.2
  • 2
    • 0029963611 scopus 로고    scopus 로고
    • Pieces of the schizophrenia puzzle fall into place
    • DOI 10.1016/S0896-6273(00)80090-2
    • Andreasen NC. Pieces of the schizophrenia puzzle fall into place. Neuron 1996; 16: 697-700. (Pubitemid 26124047)
    • (1996) Neuron , vol.16 , Issue.4 , pp. 697-700
    • Andreasen, N.C.1
  • 4
    • 45049084299 scopus 로고    scopus 로고
    • Association between interleukin-3 receptor alpha polymorphism and schizophrenia in the Chinese population
    • Sun S, Wang F, Wei J, Cao LY, Wu GY, Lu L et al. Association between interleukin-3 receptor alpha polymorphism and schizophrenia in the Chinese population. Neurosci Lett 2008; 440: 35-37.
    • (2008) Neurosci Lett , vol.440 , pp. 35-37
    • Sun, S.1    Wang, F.2    Wei, J.3    Cao, L.Y.4    Wu, G.Y.5    Lu, L.6
  • 5
    • 64449083089 scopus 로고    scopus 로고
    • A family-based study of the IL3RA gene on susceptibility to schizophrenia in a Chinese Han population
    • Sun S, Wei J, Li H, Jin S, Li P, Ju G et al. A family-based study of the IL3RA gene on susceptibility to schizophrenia in a Chinese Han population. Brain Res 2009; 1268: 13-16.
    • (2009) Brain Res , vol.1268 , pp. 13-16
    • Sun, S.1    Wei, J.2    Li, H.3    Jin, S.4    Li, P.5    Ju, G.6
  • 7
    • 50449100461 scopus 로고    scopus 로고
    • Identification of loci associated with schizophrenia by genome-wide association and follow-up
    • O'Donovan MC, Craddock N, Norton N, Williams H, Peirce T, Moskvina V et al. Identification of loci associated with schizophrenia by genome-wide association and follow-up. Nat Genet 2008; 40: 1053-1055.
    • (2008) Nat Genet , vol.40 , pp. 1053-1055
    • O'Donovan, M.C.1    Craddock, N.2    Norton, N.3    Williams, H.4    Peirce, T.5    Moskvina, V.6
  • 9
    • 72949110176 scopus 로고    scopus 로고
    • Replication of association between schizophrenia and ZNF804A in the Irish Case-Control Study of Schizophrenia sample
    • Riley B, Thiselton D, Maher BS, Bigdeli T, Wormley B, McMichael GO et al. Replication of association between schizophrenia and ZNF804A in the Irish Case-Control Study of Schizophrenia sample. Mol Psychiatry 2010; 15: 29-37.
    • (2010) Mol Psychiatry , vol.15 , pp. 29-37
    • Riley, B.1    Thiselton, D.2    Maher, B.S.3    Bigdeli, T.4    Wormley, B.5    McMichael, G.O.6
  • 13
    • 68449096727 scopus 로고    scopus 로고
    • Common variants on chromosome 6p22.1 are associated with schizophrenia
    • Shi J, Levinson DF, Duan J, Sanders AR, Zheng Y, Pe'er I et al. Common variants on chromosome 6p22.1 are associated with schizophrenia. Nature 2009; 460: 753-757.
    • (2009) Nature , vol.460 , pp. 753-757
    • Shi, J.1    Levinson, D.F.2    Duan, J.3    Sanders, A.R.4    Zheng, Y.5    Pe'Er, I.6
  • 15
    • 77955426959 scopus 로고    scopus 로고
    • Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort
    • Athanasiu L, Mattingsdal M, Kahler AK, Brown A, Gustafsson O, Agartz I et al. Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort. J Psychiatr Res 2010; 44: 748-753.
    • (2010) J Psychiatr Res , vol.44 , pp. 748-753
    • Athanasiu, L.1    Mattingsdal, M.2    Kahler, A.K.3    Brown, A.4    Gustafsson, O.5    Agartz, I.6
  • 16
    • 67649584052 scopus 로고    scopus 로고
    • Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder
    • Holmans P, Green EK, Pahwa JS, Ferreira MAR, Purcell SM, Sklar P et al. Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder. Am J Med Genet 2009; 85: 13-24.
    • (2009) Am J Med Genet , vol.85 , pp. 13-24
    • Holmans, P.1    Green, E.K.2    Pahwa, J.S.3    Ferreira, M.A.R.4    Purcell, S.M.5    Sklar, P.6
  • 17
    • 77952095729 scopus 로고    scopus 로고
    • Evidence of statistical epistasis between DISC1, CIT and NDEL1 impacting risk for schizophrenia: Biological validation with functional neuroimaging
    • Nicodemus KK, Callicott JH, Higier RG, Luna A, Nixon DC, Lipska BK et al. Evidence of statistical epistasis between DISC1, CIT and NDEL1 impacting risk for schizophrenia: biological validation with functional neuroimaging. Hum Genet 2010; 127: 441-452.
    • (2010) Hum Genet , vol.127 , pp. 441-452
    • Nicodemus, K.K.1    Callicott, J.H.2    Higier, R.G.3    Luna, A.4    Nixon, D.C.5    Lipska, B.K.6
  • 19
    • 48949087605 scopus 로고    scopus 로고
    • The anatomy of first-episode and chronic schizophrenia: An anatomical likelihood estimation meta-analysis
    • Ellison-Wright I, Glahn DC, Laird AR, Thelen SM, Bullmore E. The anatomy of first-episode and chronic schizophrenia: an anatomical likelihood estimation meta-analysis. Am J Psychiatry 2008; 165: 1015-1023.
    • (2008) Am J Psychiatry , vol.165 , pp. 1015-1023
    • Ellison-Wright, I.1    Glahn, D.C.2    Laird, A.R.3    Thelen, S.M.4    Bullmore, E.5
  • 26
    • 1242292413 scopus 로고    scopus 로고
    • Cerebral ventricular change over the first 10 years after the onset of schizophrenia
    • DOI 10.1016/j.pscychresns.2003.08.004
    • DeLisi LE, Sakuma M, Maurizio AM, Relja M, Hoff AL. Cerebral ventricular change over the first 10 years after the onset of schizophrenia. Psychiatry Res 2004; 130: 57-70. (Pubitemid 38221557)
    • (2004) Psychiatry Research - Neuroimaging , vol.130 , Issue.1 , pp. 57-70
    • DeLisi, L.E.1    Sakuma, M.2    Maurizio, A.M.3    Relja, M.4    Hoff, A.L.5
  • 27
    • 0030798020 scopus 로고    scopus 로고
    • Schizophrenia as a chronic active brain process: A study of progressive brain structural change subsequent to the onset of schizophrenia
    • DOI 10.1016/S0925-4927(97)00012-7, PII S0925492797000127
    • DeLisi LE, Sakuma M, Tew W, Kushner M, Hoff AL, Grimson R. Schizophrenia as a chronic active brain process: a study of progressive brain structural change subsequent to the onset of schizophrenia. Psychiatry Res 1997; 74: 129-140. (Pubitemid 27315863)
    • (1997) Psychiatry Research - Neuroimaging , vol.74 , Issue.3 , pp. 129-140
    • DeLisi, L.E.1    Sakuma, M.2    Tew, W.3    Kushner, M.4    Hoff, A.L.5    Grimson, R.6
  • 28
    • 0031934466 scopus 로고    scopus 로고
    • A follow-up magnetic resonance imaging study of schizophrenia: Relationship of neuroanatomical changes to clinical and neurobehavioral measures
    • DOI 10.1001/archpsyc.55.2.145
    • Gur RE, Cowell P, Turetsky BI, Gallacher F, Cannon T, Bilker W et al. A follow-up magnetic resonance imaging study of schizophrenia. Relationship of neuroanatomical changes to clinical and neurobehavioral measures. Arch Gen Psychiatry 1998; 55: 145-152. (Pubitemid 28087600)
    • (1998) Archives of General Psychiatry , vol.55 , Issue.2 , pp. 145-152
    • Gur, R.E.1    Cowell, P.2    Turetsky, B.I.3    Gallacher, F.4    Cannon, T.5    Bilker, W.6    Gur, R.C.7
  • 29
    • 0035869532 scopus 로고    scopus 로고
    • Longitudinal study of brain morphology in first episode schizophrenia
    • DOI 10.1016/S0006-3223(01)01067-8, PII S0006322301010678
    • Lieberman J, Chakos M, Wu H, Alvir J, Hoffman E, Robinson D et al. Longitudinal study of brain morphology in first episode schizophrenia. Biol Psychiatry 2001; 49: 487-499. (Pubitemid 32226407)
    • (2001) Biological Psychiatry , vol.49 , Issue.6 , pp. 487-499
    • Lieberman, J.1    Chakos, M.2    Wu, H.3    Alvir, J.4    Hoffman, E.5    Robinson, D.6    Bilder, R.7
  • 30
    • 33746773629 scopus 로고    scopus 로고
    • Progressive grey matter atrophy over the first 2-3 years of illness in first-episode schizophrenia: A tensor-based morphometry study
    • DOI 10.1016/j.neuroimage.2006.03.041, PII S1053811906002230
    • Whitford TJ, Grieve SM, Farrow TF, Gomes L, Brennan J, Harris AW et al. Progressive grey matter atrophy over the first 2-3 years of illness in first-episode schizophrenia: a tensor-based morphometry study. Neuroimage 2006; 32: 511-519. (Pubitemid 44164627)
    • (2006) NeuroImage , vol.32 , Issue.2 , pp. 511-519
    • Whitford, T.J.1    Grieve, S.M.2    Farrow, T.F.D.3    Gomes, L.4    Brennan, J.5    Harris, A.W.F.6    Gordon, E.7    Williams, L.M.8
  • 32
    • 38449085832 scopus 로고    scopus 로고
    • Association between brain-derived neurotrophic factor Val66Met gene polymorphism and progressive brain volume changes in schizophrenia
    • DOI 10.1176/appi.ajp.2007.05111903
    • Ho BC, Andreasen NC, Dawson JD, Wassink TH. Association between brain-derived neurotrophic factor Val66Met gene polymorphism and progressive brain volume changes in schizophrenia. Am J Psychiatry 2007; 164: 1890-1899. (Pubitemid 351739243)
    • (2007) American Journal of Psychiatry , vol.164 , Issue.12 , pp. 1890-1899
    • Ho, B.-C.1    Andreasen, N.C.2    Dawson, J.D.3    Wassink, T.H.4
  • 33
    • 84877092615 scopus 로고    scopus 로고
    • Progressive brain change in schizophrenia: A prospective longitudinal study of first episode patients
    • in press
    • Andreasen NC, Nopoulos P, Magnotta V, Pierson R, Ziebell S, Ho BC et al. Progressive brain change in schizophrenia: a prospective longitudinal study of first episode patients. Biol Psych (in press).
    • Biol Psych
    • Andreasen, N.C.1    Nopoulos, P.2    Magnotta, V.3    Pierson, R.4    Ziebell, S.5    Ho, B.C.6
  • 36
    • 0033048340 scopus 로고    scopus 로고
    • Improving tissue classification in MRI: A three-dimensional multispectral discriminant analysis method with automated training class selection
    • DOI 10.1097/00004728-199901000-00030
    • Harris G, Andreasen NC, Cizadlo T, Bailey JM, Bockholt HJ, Magnotta VA et al. Improving tissue classification in MRI: a threedimensional multispectral discriminant analysis method with automated training class selection. J Comput Assist Tomogr 1999; 23: 144-154. (Pubitemid 29095486)
    • (1999) Journal of Computer Assisted Tomography , vol.23 , Issue.1 , pp. 144-154
    • Harris, G.1    Andreasen, N.C.2    Cizadlo, T.3    Bailey, J.M.4    Bockholt, H.J.5    Magnotta, V.A.6    Arndt, S.7
  • 38
    • 0033005627 scopus 로고    scopus 로고
    • Measurement of brain structures with artificial neural networks: Two- and three-dimensional applications
    • Magnotta VA, Heckel D, Andreasen NC, Cizadlo T, Corson PW, Ehrhardt JC et al. Measurement of brain structures with artificial neural networks: two-and three-dimensional applications. Radiology 1999; 211: 781-790. (Pubitemid 29249481)
    • (1999) Radiology , vol.211 , Issue.3 , pp. 781-790
    • Magnotta, V.A.1    Heckel, D.2    Andreasen, N.C.3    Cizadlo, T.4    Corson, P.W.5    Ehrhardt, J.C.6    Yuh, W.T.C.7
  • 40
    • 77951653123 scopus 로고    scopus 로고
    • Replication of association between working memory and Reelin, a potential modifier gene in schizophrenia
    • Wedenoja J, Tuulio-Henriksson A, Suvisaari J, Loukola A, Paunio T, Partonen T et al. Replication of association between working memory and Reelin, a potential modifier gene in schizophrenia. Biol Psychiatry 2010; 67: 983-991.
    • (2010) Biol Psychiatry , vol.67 , pp. 983-991
    • Wedenoja, J.1    Tuulio-Henriksson, A.2    Suvisaari, J.3    Loukola, A.4    Paunio, T.5    Partonen, T.6
  • 45
    • 33646240854 scopus 로고    scopus 로고
    • Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 50 SNPs associated with the disease
    • Law AJ, Lipska BK, Weickert CS, Hyde TM, Straub RE, Hashimoto R et al. Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 50 SNPs associated with the disease. Proc Natl Acad Sci USA 2006; 103: 6747-6752.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 6747-6752
    • Law, A.J.1    Lipska, B.K.2    Weickert, C.S.3    Hyde, T.M.4    Straub, R.E.5    Hashimoto, R.6
  • 46
    • 34547792816 scopus 로고    scopus 로고
    • Interactions among genes in the ErbBNeuregulin signalling network are associated with increased susceptibility to schizophrenia
    • Benzel I, Bansal A, Browning BL, Galwey NW, Maycox PR, McGinnis R et al. Interactions among genes in the ErbBNeuregulin signalling network are associated with increased susceptibility to schizophrenia. Behav Brain Funct 2007; 3: 31.
    • (2007) Behav Brain Funct , vol.3 , pp. 31
    • Benzel, I.1    Bansal, A.2    Browning, B.L.3    Galwey, N.W.4    Maycox, P.R.5    McGinnis, R.6
  • 47
    • 68149138411 scopus 로고    scopus 로고
    • Support for NRG1 as a susceptibility factor for schizophrenia in a northern Swedish isolated population
    • Alaerts M, Ceulemans S, Forero D, Moens LN, De Zutter S, Heyrman L et al. Support for NRG1 as a susceptibility factor for schizophrenia in a northern Swedish isolated population. Arch Gen Psychiatry 2009; 66: 828-837.
    • (2009) Arch Gen Psychiatry , vol.66 , pp. 828-837
    • Alaerts, M.1    Ceulemans, S.2    Forero, D.3    Moens, L.N.4    De Zutter, S.5    Heyrman, L.6
  • 48
    • 67349169959 scopus 로고    scopus 로고
    • Association between genes of disrupted in schizophrenia 1 (DISC1) interactors and schizophrenia supports the role of the DISC1 pathway in the etiology of major mental illnesses
    • Tomppo L, Hennah W, Laherma P, Loukola A, Tuulio-Henriksson A, Suvisaari J et al. Association between genes of disrupted in schizophrenia 1 (DISC1) interactors and schizophrenia supports the role of the DISC1 pathway in the etiology of major mental illnesses. Biol Psychiatry 2009; 65: 1055-1062.
    • (2009) Biol Psychiatry , vol.65 , pp. 1055-1062
    • Tomppo, L.1    Hennah, W.2    Laherma, P.3    Loukola, A.4    Tuulio-Henriksson, A.5    Suvisaari, J.6
  • 53
    • 77649261907 scopus 로고    scopus 로고
    • Neocortical RELN promoter methylation increases significantly after puberty
    • Lintas C, Persico AM. Neocortical RELN promoter methylation increases significantly after puberty. Neuroreport 2010; 21: 114-118.
    • (2010) Neuroreport , vol.21 , pp. 114-118
    • Lintas, C.1    Persico, A.M.2
  • 55
    • 33745606684 scopus 로고    scopus 로고
    • Beyond Schizophrenia: The role of DISC1 in major mental illness
    • DOI 10.1093/schbul/sbj079
    • Hennah W, Thomson P, Peltonen L, Porteous D. Genes and schizophrenia: beyond schizophrenia: the role of DISC1 in major mental illness. Schizophr Bull 2006; 32: 409-416. (Pubitemid 43992312)
    • (2006) Schizophrenia Bulletin , vol.32 , Issue.3 , pp. 409-416
    • Hennah, W.1    Thomson, P.2    Peltonen, L.3    Porteous, D.4
  • 56
    • 66249140566 scopus 로고    scopus 로고
    • DISC-1 Leu607Phe alleles differentially affect centrosomal PCM1 localization and neurotransmitter release
    • Eastwood SL, Hodgkinson CA, Harrison PJ. DISC-1 Leu607Phe alleles differentially affect centrosomal PCM1 localization and neurotransmitter release. Mol Psychiatry 2009; 14: 556-557.
    • (2009) Mol Psychiatry , vol.14 , pp. 556-557
    • Eastwood, S.L.1    Hodgkinson, C.A.2    Harrison, P.J.3
  • 57
    • 70349465009 scopus 로고    scopus 로고
    • DISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphisms
    • Nakata K, Lipska BK, Hyde TM, Ye T, Newburn EN, Morita Yet al. DISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphisms. Proc Natl Acad Sci USA 2009; 106: 15873-15878.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 15873-15878
    • Nakata, K.1    Lipska, B.K.2    Hyde, T.M.3    Ye, T.4    Newburn, E.N.5    Morita, Y.6
  • 60
    • 56049088969 scopus 로고    scopus 로고
    • Association between a disrupted-in-schizophrenia (DISC1) single nucleotide polymorphism and schizophrenia in a combined Scandinavian case-control sample
    • Saetre P, Agartz I, De Franciscis A, Lundmark P, Djurovic S, Kahler A et al. Association between a disrupted-in-schizophrenia (DISC1) single nucleotide polymorphism and schizophrenia in a combined Scandinavian case-control sample. Schizophr Res 2008; 106: 237-241.
    • (2008) Schizophr Res , vol.106 , pp. 237-241
    • Saetre, P.1    Agartz, I.2    De Franciscis, A.3    Lundmark, P.4    Djurovic, S.5    Kahler, A.6
  • 62
    • 47949105098 scopus 로고    scopus 로고
    • DISC1 is associated with prefrontal cortical gray matter and positive symptoms in schizophrenia
    • Szeszko PR, Hodgkinson CA, Robinson DG, Derosse P, Bilder RM, Lencz T et al. DISC1 is associated with prefrontal cortical gray matter and positive symptoms in schizophrenia. Biol Psychol 2008; 79: 103-110.
    • (2008) Biol Psychol , vol.79 , pp. 103-110
    • Szeszko, P.R.1    Hodgkinson, C.A.2    Robinson, D.G.3    Derosse, P.4    Bilder, R.M.5    Lencz, T.6
  • 63
    • 64049088120 scopus 로고    scopus 로고
    • The DISC1 pathway modulates expression of neurodevelopmental, synaptogenic and sensory perception genes
    • Hennah W, Porteous D. The DISC1 pathway modulates expression of neurodevelopmental, synaptogenic and sensory perception genes. PLoS One 2009; 4: e4906.
    • (2009) PLoS One , vol.4
    • Hennah, W.1    Porteous, D.2
  • 67
    • 33745684066 scopus 로고    scopus 로고
    • Neuregulin 1 and schizophrenia: Genetics, gene expression, and neurobiology
    • Harrison PJ, Law AJ. Neuregulin 1 and schizophrenia: genetics, gene expression, and neurobiology. Biol Psychiatry 2006; 60: 132-140.
    • (2006) Biol Psychiatry , vol.60 , pp. 132-140
    • Harrison, P.J.1    Law, A.J.2
  • 68
    • 43949084738 scopus 로고    scopus 로고
    • Neuregulin 1 in neural development, synaptic plasticity and schizophrenia
    • DOI 10.1038/nrn2392, PII NRN2392
    • Mei L, Xiong WC. Neuregulin 1 in neural development, synaptic plasticity and schizophrenia. Nat Rev Neurosci 2008; 9: 437-452. (Pubitemid 351704944)
    • (2008) Nature Reviews Neuroscience , vol.9 , Issue.6 , pp. 437-452
    • Mei, L.1    Xiong, W.-C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.