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Volumn 32, Issue 3, 2006, Pages 409-416

Beyond Schizophrenia: The role of DISC1 in major mental illness

Author keywords

Animal models; Expression studies; Genetics; Neurodevelopment; Neuroimaging

Indexed keywords

DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN; GENE PRODUCT; UNCLASSIFIED DRUG; DISC1 PROTEIN, HUMAN; NERVE PROTEIN;

EID: 33745606684     PISSN: 05867614     EISSN: 17451701     Source Type: Journal    
DOI: 10.1093/schbul/sbj079     Document Type: Review
Times cited : (88)

References (65)
  • 1
    • 26444453772 scopus 로고    scopus 로고
    • Is the dysbindin gene (DTNBP1) a susceptibility gene for schizophrenia?
    • Williams NM, O'Donovan MC, Owen MJ. Is the dysbindin gene (DTNBP1) a susceptibility gene for schizophrenia? Schizophr Bull. 2005;31:800-805.
    • (2005) Schizophr Bull , vol.31 , pp. 800-805
    • Williams, N.M.1    O'Donovan, M.C.2    Owen, M.J.3
  • 2
    • 24344433989 scopus 로고    scopus 로고
    • Association between the neuregulin 1 gene and schizophrenia: A systematic review
    • Tosato S, Dazzan P, Collier D. Association between the neuregulin 1 gene and schizophrenia: a systematic review. Schizophr Bull. 2005;31:613-617.
    • (2005) Schizophr Bull , vol.31 , pp. 613-617
    • Tosato, S.1    Dazzan, P.2    Collier, D.3
  • 3
    • 33644878170 scopus 로고    scopus 로고
    • Breakthrough of the year: The runners-up
    • Breakthrough of the year: the runners-up. Science. 2005;310:1880-1885.
    • (2005) Science , vol.310 , pp. 1880-1885
  • 4
    • 0028960825 scopus 로고
    • Direct microdissection and microcloning of a translocation breakpoint region, t(1;11)(q42.2;q21), associated with schizophrenia
    • Muir WJ, Gosden CM, Brookes AJ, et al. Direct microdissection and microcloning of a translocation breakpoint region, t(1;11)(q42.2;q21), associated with schizophrenia. Cytogenet Cell Genet. 1995;70:35-40.
    • (1995) Cytogenet Cell Genet , vol.70 , pp. 35-40
    • Muir, W.J.1    Gosden, C.M.2    Brookes, A.J.3
  • 5
    • 0034702026 scopus 로고    scopus 로고
    • Disruption of two novel genes by a translocation co-segregating with schizophrenia
    • Millar JK, Wilson-Annan JC, Anderson S, et al. Disruption of two novel genes by a translocation co-segregating with schizophrenia. Hum Mol Genet. 2000;9:1415-1423.
    • (2000) Hum Mol Genet , vol.9 , pp. 1415-1423
    • Millar, J.K.1    Wilson-Annan, J.C.2    Anderson, S.3
  • 6
    • 0034235003 scopus 로고    scopus 로고
    • Chromosomal location and genomic structure of the human translin-associated factor X gene (TRAX; TSNAX) revealed by intergenic splicing to DISC1, a gene disrupted by a translocation segregating with schizophrenia
    • Millar JK, Christie S, Semple CA, Porteous DJ. Chromosomal location and genomic structure of the human translin-associated factor X gene (TRAX; TSNAX) revealed by intergenic splicing to DISC1, a gene disrupted by a translocation segregating with schizophrenia. Genomics. 2000;67:69-77.
    • (2000) Genomics , vol.67 , pp. 69-77
    • Millar, J.K.1    Christie, S.2    Semple, C.A.3    Porteous, D.J.4
  • 7
    • 0025277392 scopus 로고
    • Association within a family of a balanced autosomal translocation with major mental illness
    • St Clair D, Blackwood D, Muir W, et al. Association within a family of a balanced autosomal translocation with major mental illness. Lancet. 1990;336:13-16.
    • (1990) Lancet , vol.336 , pp. 13-16
    • St Clair, D.1    Blackwood, D.2    Muir, W.3
  • 8
    • 0034927864 scopus 로고    scopus 로고
    • Schizophrenia and affective disorders: Cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family
    • Blackwood DH, Fordyce A, Walker MT, St Clair DM, Porteous DJ, Muir WJ. Schizophrenia and affective disorders: cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family. Am J Hum Genet. 2001;69:428-433.
    • (2001) Am J Hum Genet , vol.69 , pp. 428-433
    • Blackwood, D.H.1    Fordyce, A.2    Walker, M.T.3    St Clair, D.M.4    Porteous, D.J.5    Muir, W.J.6
  • 9
    • 0037297443 scopus 로고    scopus 로고
    • Response to Amar J. Klar: The chromosome 1;11 translocation provides the best evidence supporting genetic etiology for schizophrenia and bipolar affective disorders
    • Millar JK, Thomson PA, Wray NR, Muir WJ, Blackwood DH, Porteous DJ. Response to Amar J. Klar: The chromosome 1;11 translocation provides the best evidence supporting genetic etiology for schizophrenia and bipolar affective disorders. Genetics. 2003;163:833-835.
    • (2003) Genetics , vol.163 , pp. 833-835
    • Millar, J.K.1    Thomson, P.A.2    Wray, N.R.3    Muir, W.J.4    Blackwood, D.H.5    Porteous, D.J.6
  • 11
    • 0028212541 scopus 로고
    • Segregation analysis of complex phenotypes: An application to schizophrenia and auditory P300 latency
    • Sham PC, Morton NE, Muir WJ, et al. Segregation analysis of complex phenotypes: an application to schizophrenia and auditory P300 latency. Psychiatr Genet. 1994;4:29-38.
    • (1994) Psychiatr Genet , vol.4 , pp. 29-38
    • Sham, P.C.1    Morton, N.E.2    Muir, W.J.3
  • 12
    • 0032778382 scopus 로고    scopus 로고
    • Genetic influence on auditory information processing in schizophrenia: P300 in monozygotic twins
    • Weisbrod M, Hill H, Niethammer R, Sauer H. Genetic influence on auditory information processing in schizophrenia: P300 in monozygotic twins. Biol Psychiatry. 1999;46:721-725.
    • (1999) Biol Psychiatry , vol.46 , pp. 721-725
    • Weisbrod, M.1    Hill, H.2    Niethammer, R.3    Sauer, H.4
  • 13
    • 27944502874 scopus 로고    scopus 로고
    • DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling
    • Millar JK, Pickard BS, Mackie S, et al. DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling. Science. 2005;310:1187-1191.
    • (2005) Science , vol.310 , pp. 1187-1191
    • Millar, J.K.1    Pickard, B.S.2    Mackie, S.3
  • 14
    • 23744517093 scopus 로고    scopus 로고
    • A frameshift mutation in Disrupted in Schizophrenia 1 in an American family with schizophrenia and schizoaffective disorder
    • Sachs NA, Sawa A, Holmes SE, Ross CA, Delisi LE, Margolis RL. A frameshift mutation in Disrupted in Schizophrenia 1 in an American family with schizophrenia and schizoaffective disorder. Mol Psychiatry. 2005;10:758-764.
    • (2005) Mol Psychiatry , vol.10 , pp. 758-764
    • Sachs, N.A.1    Sawa, A.2    Holmes, S.E.3    Ross, C.A.4    Delisi, L.E.5    Margolis, R.L.6
  • 16
    • 2542446307 scopus 로고    scopus 로고
    • Isolates and their potential use in complex gene mapping efforts
    • Varilo T, Peltonen L. Isolates and their potential use in complex gene mapping efforts. Curr Opin Genet Dev. 2004;14:316-323.
    • (2004) Curr Opin Genet Dev , vol.14 , pp. 316-323
    • Varilo, T.1    Peltonen, L.2
  • 17
    • 0033364825 scopus 로고    scopus 로고
    • A genomewide screen for schizophrenia genes in an isolated Finnish subpopulation, suggesting multiple susceptibility loci
    • Hovatta I, Varilo T, Suvisaari J, et al. A genomewide screen for schizophrenia genes in an isolated Finnish subpopulation, suggesting multiple susceptibility loci. Am J Hum Genet. 1999;65:1114-1124.
    • (1999) Am J Hum Genet , vol.65 , pp. 1114-1124
    • Hovatta, I.1    Varilo, T.2    Suvisaari, J.3
  • 18
    • 0035878561 scopus 로고    scopus 로고
    • Chromosome 1 loci in Finnish schizophrenia families
    • Ekelund J, Hovatta I, Parker A, et al. Chromosome 1 loci in Finnish schizophrenia families. Hum Mol Genet. 2001;10:1611-1617.
    • (2001) Hum Mol Genet , vol.10 , pp. 1611-1617
    • Ekelund, J.1    Hovatta, I.2    Parker, A.3
  • 19
    • 8744231685 scopus 로고    scopus 로고
    • Replication of 1q42 linkage in Finnish schizophrenia pedigrees
    • Ekelund J, Hennah W, Hiekkalinna T, et al. Replication of 1q42 linkage in Finnish schizophrenia pedigrees. Mol Psychiatry. 2004;9:1037-1041.
    • (2004) Mol Psychiatry , vol.9 , pp. 1037-1041
    • Ekelund, J.1    Hennah, W.2    Hiekkalinna, T.3
  • 20
    • 0028877463 scopus 로고
    • Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
    • Lander E, Kruglyak L. Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet. 1995;11:241-247.
    • (1995) Nat Genet , vol.11 , pp. 241-247
    • Lander, E.1    Kruglyak, L.2
  • 21
    • 0345530985 scopus 로고    scopus 로고
    • Haplotype transmission analysis provides evidence of association for DISC1 to schizophrenia and suggests sex-dependent effects
    • Hennah W, Varilo T, Kestila M, et al. Haplotype transmission analysis provides evidence of association for DISC1 to schizophrenia and suggests sex-dependent effects. Hum Mol Genet. 2003;12:3151-3159.
    • (2003) Hum Mol Genet , vol.12 , pp. 3151-3159
    • Hennah, W.1    Varilo, T.2    Kestila, M.3
  • 22
    • 0026410654 scopus 로고
    • A polydiagnostic application of operational criteria in studies of psychotic illness: Development and reliability of the OPCRIT system
    • McGuffin P, Farmer AE, Harvey I. A polydiagnostic application of operational criteria in studies of psychotic illness: development and reliability of the OPCRIT system. Arch Gen Psychiatry. 1991;48:764-770.
    • (1991) Arch Gen Psychiatry , vol.48 , pp. 764-770
    • McGuffin, P.1    Farmer, A.E.2    Harvey, I.3
  • 23
    • 0042780286 scopus 로고    scopus 로고
    • Genetic linkage and association between chromosome 1q and working memory function in schizophrenia
    • Gasperoni TL, Ekelund J, Huttunen M, et al. Genetic linkage and association between chromosome 1q and working memory function in schizophrenia. Am J Med Genet B Neuropsychiatr Genet. 2003;116B:8-16.
    • (2003) Am J Med Genet B Neuropsychiatr Genet , vol.116 B , pp. 8-16
    • Gasperoni, T.L.1    Ekelund, J.2    Huttunen, M.3
  • 24
    • 4444332521 scopus 로고    scopus 로고
    • Search for cognitive trait components of schizophrenia reveals a locus for verbal learning and memory on 4q and for visual working memory on 2q
    • Paunio T, Tuulio-Henriksson A, Hiekkalinna T, et al. Search for cognitive trait components of schizophrenia reveals a locus for verbal learning and memory on 4q and for visual working memory on 2q. Hum Mol Genet. 2004;13:1693-1702.
    • (2004) Hum Mol Genet , vol.13 , pp. 1693-1702
    • Paunio, T.1    Tuulio-Henriksson, A.2    Hiekkalinna, T.3
  • 25
    • 32844455739 scopus 로고    scopus 로고
    • A haplotype within the DISC1 gene is associated with visual memory functions in families with a high density of schizophrenia
    • Hennah W, Tuulio-Henriksson A, Paunio T, et al. A haplotype within the DISC1 gene is associated with visual memory functions in families with a high density of schizophrenia. Mol Psychiatry. 2005;10:1097-1103.
    • (2005) Mol Psychiatry , vol.10 , pp. 1097-1103
    • Hennah, W.1    Tuulio-Henriksson, A.2    Paunio, T.3
  • 26
    • 27744554247 scopus 로고    scopus 로고
    • Association of DISC1/TRAX haplotypes with schizophrenia, reduced prefrontal gray matter, and impaired short- and long-term memory
    • Cannon TD, Hennah W, van Erp TG, et al. Association of DISC1/TRAX haplotypes with schizophrenia, reduced prefrontal gray matter, and impaired short- and long-term memory. Arch Gen Psychiatry. 2005;62:1205-1213.
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 1205-1213
    • Cannon, T.D.1    Hennah, W.2    Van Erp, T.G.3
  • 27
    • 0037953124 scopus 로고    scopus 로고
    • Linkage of schizophrenia with chromosome 1q loci in Taiwanese families
    • Hwu HG, Liu CM, Fann CS, Ou-Yang WC, Lee SF. Linkage of schizophrenia with chromosome 1q loci in Taiwanese families. Mol Psychiatry. 2003;8:445-452.
    • (2003) Mol Psychiatry , vol.8 , pp. 445-452
    • Hwu, H.G.1    Liu, C.M.2    Fann, C.S.3    Ou-Yang, W.C.4    Lee, S.F.5
  • 28
    • 25844501532 scopus 로고    scopus 로고
    • Genome-wide linkage scan in schizoaffective disorder: Significant evidence for linkage at 1q42 close to DISC1, and suggestive evidence at 22q11 and 19p13
    • Hamshere ML, Bennett P, Williams N, et al. Genome-wide linkage scan in schizoaffective disorder: significant evidence for linkage at 1q42 close to DISC1, and suggestive evidence at 22q11 and 19p13. Arch Gen Psychiatry. 2005;62:1081-1088.
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 1081-1088
    • Hamshere, M.L.1    Bennett, P.2    Williams, N.3
  • 29
    • 12444256025 scopus 로고    scopus 로고
    • Genome scan of pedigrees multiply affected with bipolar disorder provides further support for the presence of a susceptibility locus on chromosome 12q23-q24, and suggests the presence of additional loci on 1p and 1q
    • Curtis D, Kalsi G, Brynjolfsson J, et al. Genome scan of pedigrees multiply affected with bipolar disorder provides further support for the presence of a susceptibility locus on chromosome 12q23-q24, and suggests the presence of additional loci on 1p and 1q. Psychiatr Genet. 2003;13:77-84.
    • (2003) Psychiatr Genet , vol.13 , pp. 77-84
    • Curtis, D.1    Kalsi, G.2    Brynjolfsson, J.3
  • 30
    • 11244302487 scopus 로고    scopus 로고
    • A genome scan and follow-up study identify a bipolar disorder susceptibility locus on chromosome 1q42
    • Macgregor S, Visscher PM, Knott SA, et al. A genome scan and follow-up study identify a bipolar disorder susceptibility locus on chromosome 1q42. Mol Psychiatry. 2004;9:1083-1090.
    • (2004) Mol Psychiatry , vol.9 , pp. 1083-1090
    • Macgregor, S.1    Visscher, P.M.2    Knott, S.A.3
  • 31
    • 13044281675 scopus 로고    scopus 로고
    • A high-density genome scan detects evidence for a bipolar-disorder susceptibility locus on 13q32 and other potential loci on 1q32 and 18p11.2
    • Detera-Wadleigh SD, Badner JA, Berrettini WH, et al. A high-density genome scan detects evidence for a bipolar-disorder susceptibility locus on 13q32 and other potential loci on 1q32 and 18p11.2. Proc Natl Acad Sci U S A. 1999;96:5604-5609.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 5604-5609
    • Detera-Wadleigh, S.D.1    Badner, J.A.2    Berrettini, W.H.3
  • 32
    • 6344255274 scopus 로고    scopus 로고
    • Disrupted in Schizophrenia 1 (DISC1): Association with schizophrenia, schizoaffective disorder, and bipolar disorder
    • Hodgkinson CA, Goldman D, Jaeger J, et al. Disrupted in Schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder. Am J Hum Genet. 2004;75:862-872.
    • (2004) Am J Hum Genet , vol.75 , pp. 862-872
    • Hodgkinson, C.A.1    Goldman, D.2    Jaeger, J.3
  • 33
    • 20844463251 scopus 로고    scopus 로고
    • Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia
    • Callicott JH, Straub RE, Pezawas L, et al. Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia. Proc Natl Acad Sci U S A. 2005;102:8627-8632.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 8627-8632
    • Callicott, J.H.1    Straub, R.E.2    Pezawas, L.3
  • 35
    • 21844435448 scopus 로고    scopus 로고
    • Association between the TRAX/DISC locus and both bipolar disorder and schizophrenia in the Scottish population
    • Thomson PA, Wray NR, Millar JK, et al. Association between the TRAX/DISC locus and both bipolar disorder and schizophrenia in the Scottish population. Mol Psychiatry. 2005;10:657-668, 616.
    • (2005) Mol Psychiatry , vol.10 , pp. 657-668
    • Thomson, P.A.1    Wray, N.R.2    Millar, J.K.3
  • 36
    • 24044449980 scopus 로고    scopus 로고
    • DISC1 and neurocognitive function in schizophrenia
    • Burdick KE, Hodgkinson CA, Szeszko PR, et al. DISC1 and neurocognitive function in schizophrenia. Neuroreport. 2005;16:1399-1402.
    • (2005) Neuroreport , vol.16 , pp. 1399-1402
    • Burdick, K.E.1    Hodgkinson, C.A.2    Szeszko, P.R.3
  • 38
    • 12344327212 scopus 로고    scopus 로고
    • Schizophrenia genes, gene expression, and neuropathology: On the matter of their convergence
    • Harrison PJ, Weinberger DR. Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence. Mol Psychiatry. 2005;10:40-68.
    • (2005) Mol Psychiatry , vol.10 , pp. 40-68
    • Harrison, P.J.1    Weinberger, D.R.2
  • 39
    • 4444315059 scopus 로고    scopus 로고
    • Association study of polymorphisms in the 5′ upstream region of human DISC1 gene with schizophrenia
    • Kockelkorn TT, Arai M, Matsumoto H, et al. Association study of polymorphisms in the 5′ upstream region of human DISC1 gene with schizophrenia. Neurosci Lett. 2004;368:41-45.
    • (2004) Neurosci Lett , vol.368 , pp. 41-45
    • Kockelkorn, T.T.1    Arai, M.2    Matsumoto, H.3
  • 40
    • 26844476910 scopus 로고    scopus 로고
    • Association study of the DISC1/TRAX locus with schizophrenia in a Japanese population
    • Zhang X, Tochigi M, Ohashi J, et al. Association study of the DISC1/TRAX locus with schizophrenia in a Japanese population. Schizophr Res. 2005;79:175-180.
    • (2005) Schizophr Res , vol.79 , pp. 175-180
    • Zhang, X.1    Tochigi, M.2    Ohashi, J.3
  • 41
    • 33846819016 scopus 로고    scopus 로고
    • Case-control association study of Disrupted-in-Schizophrenia-1 (DISC1) gene and schizophrenia in the Chinese population
    • doi:10.1016/j.jpsychires.2006.1001.1001. Accessed April 21, 2006
    • Chen QY, Chen Q, Feng GY, et al. Case-control association study of Disrupted-in-Schizophrenia-1 (DISC1) gene and schizophrenia in the Chinese population. J Psychiatr Res. 2006;doi:10.1016/j.jpsychires.2006.1001.1001. Accessed April 21, 2006.
    • (2006) J Psychiatr Res
    • Chen, Q.Y.1    Chen, Q.2    Feng, G.Y.3
  • 42
    • 0042622356 scopus 로고    scopus 로고
    • Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth
    • Miyoshi K, Honda A, Baba K, et al. Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth. Mol Psychiatry. 2003;8:685-694.
    • (2003) Mol Psychiatry , vol.8 , pp. 685-694
    • Miyoshi, K.1    Honda, A.2    Baba, K.3
  • 43
    • 0037422609 scopus 로고    scopus 로고
    • Disrupted-in-Schizophrenia-1 (DISC-1): Mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth
    • Ozeki Y, Tomoda T, Kleiderlein J, et al. Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth. Proc Natl Acad Sci U S A. 2003;100:289-294.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 289-294
    • Ozeki, Y.1    Tomoda, T.2    Kleiderlein, J.3
  • 44
    • 0037766786 scopus 로고    scopus 로고
    • DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: Regulation and loss of interaction with mutation
    • Morris JA, Kandpal G, Ma L, Austin CP. DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation. Hum Mol Genet. 2003;12:1591-1608.
    • (2003) Hum Mol Genet , vol.12 , pp. 1591-1608
    • Morris, J.A.1    Kandpal, G.2    Ma, L.3    Austin, C.P.4
  • 45
    • 2342539835 scopus 로고    scopus 로고
    • Disrupted in Schizophrenia 1 (DISC1) is a multi-compartmentalized protein that predominantly localizes to mitochondria
    • James R, Adams RR, Christie S, Buchanan SR, Porteous DJ, Millar JK. Disrupted in Schizophrenia 1 (DISC1) is a multi-compartmentalized protein that predominantly localizes to mitochondria. Mol Cell Neurosci. 2004;26:112-122.
    • (2004) Mol Cell Neurosci , vol.26 , pp. 112-122
    • James, R.1    Adams, R.R.2    Christie, S.3    Buchanan, S.R.4    Porteous, D.J.5    Millar, J.K.6
  • 46
    • 20144375954 scopus 로고    scopus 로고
    • Subcellular targeting of DISC1 is dependent on a domain independent from the Nudel binding site
    • Brandon NJ, Schurov I, Camargo LM, et al. Subcellular targeting of DISC1 is dependent on a domain independent from the Nudel binding site. Mol Cell Neurosci. 2005;28:613-624.
    • (2005) Mol Cell Neurosci , vol.28 , pp. 613-624
    • Brandon, N.J.1    Schurov, I.2    Camargo, L.M.3
  • 47
    • 27744442959 scopus 로고    scopus 로고
    • A functional link between Disrupted-In-Schizophrenia 1 and the eukaryotic translation initiation factor 3
    • Ogawa F, Kasai M, Akiyama T. A functional link between Disrupted-In-Schizophrenia 1 and the eukaryotic translation initiation factor 3. Biochem Biophys Res Commun. 2005;338:771-776.
    • (2005) Biochem Biophys Res Commun , vol.338 , pp. 771-776
    • Ogawa, F.1    Kasai, M.2    Akiyama, T.3
  • 48
    • 12844265300 scopus 로고    scopus 로고
    • A form of DISC1 enriched in nucleus: Altered subcellular distribution in orbitofrontal cortex in psychosis and substance/alcohol abuse
    • Sawamura N, Sawamura-Yamamoto T, Ozeki Y, Ross CA, Sawa A. A form of DISC1 enriched in nucleus: altered subcellular distribution in orbitofrontal cortex in psychosis and substance/alcohol abuse. Proc Natl Acad Sci U S A. 2005;102:1187-1192.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 1187-1192
    • Sawamura, N.1    Sawamura-Yamamoto, T.2    Ozeki, Y.3    Ross, C.A.4    Sawa, A.5
  • 49
    • 28344457312 scopus 로고    scopus 로고
    • Disrupted in Schizophrenia 1 (DISC1): Subcellular targeting and induction of ring mitochondria
    • Millar JK, James R, Christie S, Porteous DJ. Disrupted in Schizophrenia 1 (DISC1): subcellular targeting and induction of ring mitochondria. Mol Cell Neurosci. 2005;30:477-484.
    • (2005) Mol Cell Neurosci , vol.30 , pp. 477-484
    • Millar, J.K.1    James, R.2    Christie, S.3    Porteous, D.J.4
  • 50
    • 33645828206 scopus 로고    scopus 로고
    • Expression of DISC1 binding partners is reduced in schizophrenia and associated with DISC1 SNPs
    • Lipska BK, Peters T, Hyde TM, et al. Expression of DISC1 binding partners is reduced in schizophrenia and associated with DISC1 SNPs. Hum Mol Genet. 2006;15:1245-1258.
    • (2006) Hum Mol Genet , vol.15 , pp. 1245-1258
    • Lipska, B.K.1    Peters, T.2    Hyde, T.M.3
  • 51
    • 11244277000 scopus 로고    scopus 로고
    • Expression of Disrupted in Schizophrenia 1 (DISC1) protein in the adult and developing mouse brain indicates its role in neurodevelopment
    • Schurov IL, Handford EJ, Brandon NJ, Whiting PJ. Expression of Disrupted in Schizophrenia 1 (DISC1) protein in the adult and developing mouse brain indicates its role in neurodevelopment. Mol Psychiatry. 2004;9:1100-1110.
    • (2004) Mol Psychiatry , vol.9 , pp. 1100-1110
    • Schurov, I.L.1    Handford, E.J.2    Brandon, N.J.3    Whiting, P.J.4
  • 53
    • 28544453286 scopus 로고    scopus 로고
    • A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development
    • Kamiya A, Kubo KI, Tomoda T, et al. A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development. Nat Cell Biol. 2005;7:1067-1078.
    • (2005) Nat Cell Biol , vol.7 , pp. 1067-1078
    • Kamiya, A.1    Kubo, K.I.2    Tomoda, T.3
  • 55
    • 23844559241 scopus 로고    scopus 로고
    • Complete loss of Ndel1 results in neuronal migration defects and early embryonic lethality
    • Sasaki S, Mori D, Toyo-oka K, et al. Complete loss of Ndel1 results in neuronal migration defects and early embryonic lethality. Mol Cell Biol. 2005;25:7812-7827.
    • (2005) Mol Cell Biol , vol.25 , pp. 7812-7827
    • Sasaki, S.1    Mori, D.2    Toyo-oka, K.3
  • 56
    • 0031848149 scopus 로고    scopus 로고
    • Graded reduction of Pafah1b1 (Lis1) activity results in neuronal migration defects and early embryonic lethality
    • Hirotsune S, Fleck MW, Gambello MJ, et al. Graded reduction of Pafah1b1 (Lis1) activity results in neuronal migration defects and early embryonic lethality. Nat Genet. 1998;19:333-339.
    • (1998) Nat Genet , vol.19 , pp. 333-339
    • Hirotsune, S.1    Fleck, M.W.2    Gambello, M.J.3
  • 58
    • 33745599448 scopus 로고    scopus 로고
    • Effect of antipsychotic drugs on DISC1 and dysbindin expression in mouse frontal cortex and hippocampus
    • doi:10.1007/s00702-00005-00414-00701. Accessed April 21, 2006
    • Chiba S, Hashimoto R, Hattori S, et al. Effect of antipsychotic drugs on DISC1 and dysbindin expression in mouse frontal cortex and hippocampus. J Neural Transm. 2006; doi:10.1007/s00702-00005-00414-00701. Accessed April 21, 2006.
    • (2006) J Neural Transm
    • Chiba, S.1    Hashimoto, R.2    Hattori, S.3
  • 59
    • 20144374692 scopus 로고    scopus 로고
    • Inhibition of NUDEL (nuclear distribution element-like)-oligopeptidase activity by Disrupted-in-Schizophrenia 1
    • Hayashi MA, Portaro FC, Bastos MF, et al. Inhibition of NUDEL (nuclear distribution element-like)-oligopeptidase activity by Disrupted-in-Schizophrenia 1. Proc Natl Acad Sci U S A. 2005;102:3828-3833.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 3828-3833
    • Hayashi, M.A.1    Portaro, F.C.2    Bastos, M.F.3
  • 60
    • 7444263014 scopus 로고    scopus 로고
    • Association analysis of FEZ1 variants with schizophrenia in Japanese cohorts
    • Yamada K, Nakamura K, Minabe Y, et al. Association analysis of FEZ1 variants with schizophrenia in Japanese cohorts. Biol Psychiatry. 2004;56:683-690.
    • (2004) Biol Psychiatry , vol.56 , pp. 683-690
    • Yamada, K.1    Nakamura, K.2    Minabe, Y.3
  • 62
    • 5144222593 scopus 로고    scopus 로고
    • Mitotic spindle regulation by Nde1 controls cerebral cortical size
    • Feng Y, Walsh CA. Mitotic spindle regulation by Nde1 controls cerebral cortical size. Neuron. 2004;44:279-293.
    • (2004) Neuron , vol.44 , pp. 279-293
    • Feng, Y.1    Walsh, C.A.2
  • 63
    • 0029085025 scopus 로고
    • A mouse homolog of dunce, a gene important for learning and memory in Drosophila, is preferentially expressed in olfactory receptor neurons
    • Cherry JA, Davis RL. A mouse homolog of dunce, a gene important for learning and memory in Drosophila, is preferentially expressed in olfactory receptor neurons. J Neurobiol. 1995;28:102-113.
    • (1995) J Neurobiol , vol.28 , pp. 102-113
    • Cherry, J.A.1    Davis, R.L.2
  • 64
    • 0036790883 scopus 로고    scopus 로고
    • Antidepressant-like profile and reduced sensitivity to rolipram in mice deficient in the PDE4D phosphodiesterase enzyme
    • Zhang HT, Huang Y, Jin SL, et al. Antidepressant-like profile and reduced sensitivity to rolipram in mice deficient in the PDE4D phosphodiesterase enzyme. Neuropsychopharmacology. 2002;27:587-595.
    • (2002) Neuropsychopharmacology , vol.27 , pp. 587-595
    • Zhang, H.T.1    Huang, Y.2    Jin, S.L.3
  • 65
    • 1342264246 scopus 로고    scopus 로고
    • Antidepressant effects of inhibitors of cAMP phosphodiesterase (PDE4)
    • O'Donnell JM, Zhang HT. Antidepressant effects of inhibitors of cAMP phosphodiesterase (PDE4). Trends Pharmacol Sci. 2004;25:158-163.
    • (2004) Trends Pharmacol Sci , vol.25 , pp. 158-163
    • O'Donnell, J.M.1    Zhang, H.T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.