Neural mechanisms of a genome-wide supported psychosis variant

Science

Volumn 324, Issue 5927, 2009, Pages 605-

  Esslinger, Christine ^a   Walter, Henrik ^b   Kirsch, Peter ^a   Erk, Susanne ^b   Schnell, Knut ^b   Arnold, Claudia ^b   Haddad, Leila ^a   Mier, Daniela ^a   Boberfeld, Carola Opitz Von ^b   Raab, Kyeon ^a   Witt, Stephanie H ^a   Rietschel, Marcella ^a   Cichon, Sven ^b   Meyer Lindenberg, Andreas ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ETIOLOGY; GENETIC ANALYSIS; GENOME; GENOTYPE; NEUROLOGY; PHENOTYPE;

AMYGDALOID NUCLEUS; ARTICLE; BIPOLAR DISORDER; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HIPPOCAMPUS; HOMOZYGOTE; HUMAN; PHENOTYPE; PREFRONTAL CORTEX; PRIORITY JOURNAL; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM; ADULT; BRAIN MAPPING; EMOTIONAL DISORDER; FEMALE; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENETICS; MALE; MENTAL FUNCTION; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PHYSIOLOGY;

KRUPPEL LIKE FACTOR; ZNF804A PROTEIN, HUMAN;

ADULT; AFFECTIVE SYMPTOMS; BIPOLAR DISORDER; BRAIN MAPPING; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HIPPOCAMPUS; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MAGNETIC RESONANCE IMAGING; MALE; MENTAL PROCESSES; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; PREFRONTAL CORTEX; SCHIZOPHRENIA;

EID: 65549147665     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1167768     Document Type: Article

References (8)

1. K. E. Stephan, T. Baldeweg, K. J. Friston, Biol. Psychiatry 59, 929 (2006).
2. A. S. Meyer-Lindenberg et al., Arch. Gen. Psychiatry 62, 379 (2005).
3. M. C. O'Donovan et al., Nat. Genet. 40, 1053 (2008).
4. A. Meyer-Lindenberg, D. R. Weinberger, Nat. Rev. Neurosci. 7, 818 (2006).
5. Materials and methods are available as supporting material on Science Online.
6. R. Rasetti et al., Am. J. Psychiatry 166, 216 (2009).
7. A. Meyer-Lindenberg et al., Neuroimage 40, 655 (2008).
8. Funding was provided by Bundesministerium für Bildung und Forschung (Nationales Genomforschungsnetz plus MooDs) and Deutsche Forschungemeinschaft (SFB 636-B7). We thank T. Paul, B. Newport, D. Gass, O. Grimm, and C. Sauer for data acquisition; T. Demirakca and M. Ruf for technical support; and T. Schulze and M. Nöthen for helpful discussion.