A potentiator induces conformational changes on the recombinant CFTR nucleotide binding domains in solution

Cellular and Molecular Life Sciences

Volumn 69, Issue 21, 2012, Pages 3701-3713

  Galfre, Elena ^a   Galeno, Lauretta ^a   Moran, Oscar ^a  

^a CNR   (Italy)

Author keywords

ABC transporter; CFTR; Cystic fibrosis; Nucleotide binding domain; Potentiator; Protein stability; Protein structure; X ray scattering

Indexed keywords

2 PYRIMIDIN 7,8 BENZOFLAVONE; ADENOSINE TRIPHOSPHATE; BENZOFLAVONE DERIVATIVE; GUANIDINE; NUCLEOTIDE; RECOMBINANT PROTEIN; TRANSMEMBRANE CONDUCTANCE REGULATOR; UNCLASSIFIED DRUG;

ARTICLE; FLUORESCENCE ANALYSIS; HYDROLYSIS; MEASUREMENT; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN STABILITY; PROTEIN STRUCTURE; RADIATION SCATTERING;

ADENOSINE TRIPHOSPHATE; BENZOFLAVONES; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DIMERIZATION; GUANIDINE; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SCATTERING, SMALL ANGLE; SOLUTIONS; SPECTROMETRY, FLUORESCENCE; THERMODYNAMICS; X-RAY DIFFRACTION;

EID: 84867891696     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-012-1049-7     Document Type: Article

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